List of works by Agneta Nordberg

(S)-(-)-[11C]nicotine binding assessed by PET: a dual tracer model evaluated in the rhesus monkey brain

scientific article published in September 1998

A Cross-Validation of FDG- and Amyloid-PET Biomarkers in Mild Cognitive Impairment for the Risk Prediction to Dementia due to Alzheimer's Disease in a Clinical Setting

scientific article

A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

scientific article

A critical discussion of the role of neuroimaging in mild cognitive impairment

scientific article

A follow-up study of the family with the Swedish APP 670/671 Alzheimer's disease mutation.

scientific article published in November 1999

A muscarinic receptor type in human lymphocytes: a comparison of 3H-QNB binding to intact lymphocytes and lysed lymphocyte membranes.

scientific article published in April 1986

A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?

scientific article

A review of butyrylcholinesterase as a therapeutic target in the treatment of Alzheimer's disease

scientific article published on 07 March 2013

AMYPAD Diagnostic and Patient Management Study: Rationale and design

scientific article published on 16 October 2018

Abeta(25-35) attenuated SREBP level in nuclear extracts of serum-deprived human neuroblastoma cells.

scientific article

Abuse is in the eye of the beholder. Report by family members about abuse of demented persons in home care. A total population-based study

scientific article published on 01 December 1993

Acetylcholine synthesizing activity and nicotinic binding sites in rat hind limb muscles during reinnervation

scientific article published on 01 December 1982

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

scientific article

Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: inverse correlation with A beta levels.

scientific article published on 13 November 2006

Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels

scientific article

Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging

scientific article published on 2 July 2015

Amyloid plaque imaging in vivo: current achievement and future prospects.

scientific article published on March 2008

Amyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease

scientific article published on 28 September 2016

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.

scientific article published on 11 June 2013

Amyloid, tau, and astrocyte pathology in autosomal-dominant Alzheimer's disease variants: AβPParc and PSEN1DE9

scientific article published on 25 June 2020

Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

scientific article published on 01 November 2020

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs.

scientific article

Anatoxin-a a potent ligand for nicotinic cholinergic receptors in rat brain

scientific article published on 01 March 1987

Apolipoprotein E epsilon4 allele decreases functional connectivity in Alzheimer's disease as measured by EEG coherence

scientific article

Apolipoprotein E epsilon4 allele, skin vessel reactivity and vascular risk factors in Alzheimer's disease

scientific article

Apolipoprotein E varepsilon4 allele has an impact on vascular reactivity in Alzheimer's disease.

scientific article

Apolipoprotein ε4 modulates phenotype of butyrylcholinesterase in CSF of patients with Alzheimer's disease.

scientific article

Application of PET in dementia disorders.

scientific article published on January 1996

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Astrocyte Biomarkers in Alzheimer's Disease

scientific article published on 02 January 2019

Astrocytosis measured by ¹¹C-deprenyl PET correlates with decrease in gray matter density in the parahippocampus of prodromal Alzheimer's patients

scientific article published on 31 July 2014

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study.

scientific article published on 17 April 2015

Atropine modulates changes in striatal muscarinic receptor binding sites in barbital abstinence in the rat

scientific article published on 01 July 1982

Attempts to visualize nicotinic receptors in the brain of monkey and man by positron emission tomography

scientific article

Autoradiographic comparison of [3H](-)nicotine, [3H]cytisine and [3H]epibatidine binding in relation to vesicular acetylcholine transport sites in the temporal cortex in Alzheimer's disease

scientific article published on 01 January 1999

Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease

scientific article published in February 2012

Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.

scientific article

Beta-estradiol attenuate amyloid beta-peptide toxicity via nicotinic receptors.

scientific article published in November 1999

Biochemical changes in dementia disorders of Alzheimer type (AD/SDAT).

scientific article published in January 1983

Biological subtypes of Alzheimer disease: A systematic review and meta-analysis

scientific article published on 11 February 2020

Biomarkers for Alzheimer's disease therapeutic trials

scientific article published on 02 December 2010

Biphasic effect of tacrine on acetylcholine release in rat brain via M1 and M2 receptors

scientific article published in July 1996

Brain activation in young and older adults during implicit and explicit retrieval

scientific article published in May 1997

Brain regions associated with episodic retrieval in normal aging and Alzheimer's disease

scientific article published on June 1999

Case Report of Complex Amyotrophic Lateral Sclerosis with Cognitive Impairment and Cortical Amyloid Deposition

scientific article published in August 2015

Catecholamine topochemistry in human basal ganglia. Comparison between normal and Alzheimer brains

scientific article published in April 1985

Cerebral glucose metabolism, cerebrospinal fluid-beta-amyloid1-42 (CSF-Abeta42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients

scientific article

Change in nicotinic receptor subtypes in temporal cortex of Alzheimer brains

scientific article published in April 1988

Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease

scientific article published on 9 February 2015

Changes in brain 11C-nicotine binding sites in patients with mild Alzheimer's disease following rivastigmine treatment as assessed by PET.

scientific article published on 20 February 2007

Changes in cholinergic activity in human hippocampus following chronic alcohol abuse

scientific article published in January 1983

Changes in cholinergic function in rat brain late in abstinence after chronic barbital treatment

scientific article published on 01 February 1981

Changes in populations of cholinergic binding sites in brain after chronic exposure to barbital in rats

scientific article published in August 1982

Changes in the activity and protein levels of CSF acetylcholinesterases in relation to cognitive function of patients with mild Alzheimer's disease following chronic donepezil treatment.

scientific article published in August 2006

Characterization of muscarinic receptor subtypes in Alzheimer and control brain cortices by selective muscarinic antagonists

scientific article published on November 20, 1992

Characterization of the brain β-amyloid isoform pattern at different ages of Tg2576 mice.

scientific article published on 23 February 2011

Cholinergic activity in hippocampus in chronic alcoholism

scientific article

Cholinergic receptors in human hippocampus-- regional distribution and variance with age ⬇️

scientific article published on November 9, 1981

Cholinergic topography in Alzheimer brains: a comparison with changes in the monoaminergic profile

scientific article published on 01 January 1987

Chronic ethanol treatment decreases [3H]epibatidine and [3H]nicotine binding and differentially regulates mRNA levels of nicotinic acetylcholine receptor subunits expressed in M10 and SH-SY5Y neuroblastoma cells.

scientific article

Chronic fluoride toxicity decreases the number of nicotinic acetylcholine receptors in rat brain

scientific article published in November 2002

Chronic nicotine exposure in rat: A behavioural and biochemical study of tolerance ⬇️

scientific article published on 01 August 1981

Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw).

scientific article

Chronic treatments with tacrine and (-)-nicotine induce different changes of nicotinic and muscarinic acetylcholine receptors in the brain of aged rat.

scientific article published in March 2002

Clinical impact of 18F-FDG-PET among memory clinic patients with uncertain diagnosis

scientific article published on 31 July 2020

Clinical impact of [F]flutemetamol PET among memory clinic patients with an unclear diagnosis

Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

scientific article

Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

scientific article

Co-digestion of energy crops and the source-sorted organic fraction of municipal solid waste.

scientific article

Combination of 18F-FDG PET and cerebrospinal fluid biomarkers as a better predictor of the progression to Alzheimer's disease in mild cognitive impairment patients

scientific article published in January 2013

Comparability of [18F]THK5317 and [11C]PIB blood flow proxy images with [18F]FDG positron emission tomography in Alzheimer's disease

scientific article published on 22 April 2016

Comparative analysis of nicotine-like receptor-ligand interactions in rodent brain homogenate

scientific article published in July 1985

Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains.

scientific article published on 11 December 2017

Comparative in-vitro and in-vivo quantifications of pathological tau deposits and their association with neurodegeneration in tauopathy mouse models

scientific article

Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease.

scientific article

Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.

scientific article published on 20 December 2012

Comparison of subtyping methods for neuroimaging studies in Alzheimer's disease: a call for harmonization

scientific article published on 09 November 2020

Concordance and Diagnostic Accuracy of [11C]PIB PET and Cerebrospinal Fluid Biomarkers in a Sample of Patients with Mild Cognitive Impairment and Alzheimer's Disease

scientific article published in January 2015

Correction: Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels.

scientific article

Correlation of oxidative stress and the loss of the nicotinic receptor alpha 4 subunit in the temporal cortex of patients with Alzheimer's disease.

scientific article

Correlations between Alzheimer's Disease Cerebrospinal Fluid Biomarkers and Cerebral Glucose Metabolism after 12 Months of Phenserine Treatment.

scientific article published in August 2015

Cortical laminar tau deposits and activated astrocytes in Alzheimer's disease visualised by 3H-THK5117 and 3H-deprenyl autoradiography

scientific article published on 04 April 2017

Cortical microstructural correlates of astrocytosis in autosomal dominant Alzheimer disease

scientific article published on 14 April 2020

Coupling of muscarinic receptors to GTP proteins in postmortem human brain--alterations in Alzheimer's disease

scientific article published in February 1993

Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging

Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species

scientific article published on 19 August 2018

Decreased nicotinic receptors in PC12 cells and rat brains influenced by fluoride toxicity--a mechanism relating to a damage at the level in post-transcription of the receptor genes

scientific journal article

Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain

scientific article published on June 1999

Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease

scientific article

Decreased uptake and binding of 11C-nicotine in brain of Alzheimer patients as visualized by positron emission tomography

scientific article

Defeating Alzheimer's disease and other dementias: a priority for European science and society

scientific article published on April 2016

Degree of abnormality is associated with rate of change in measures of beta-amyloid, glucose metabolism and cognition in an autopsy-verified Alzheimer's disease case

scientific article published on 12 December 2014

Dementia in 2014. Towards early diagnosis in Alzheimer disease.

scientific article

Development of [11C]/[3H]THK-5351 - A potential novel carbon-11 tau imaging PET radioligand

scientific article

Development of ligands for in vivo imaging of cerebral nicotinic receptors

scientific article

Different Positron Emission Tomography Tau Tracers Bind to Multiple Binding Sites on the Tau Fibril: Insight from Computational Modeling.

scientific article published on 9 April 2018

Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients

scientific article

Different interactions of steric isomers of hexobarbital to muscarinic agonist and antagonist binding sites in brain ⬇️

scientific article published on September 17, 1984

Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity

scientific article published on 17 June 2011

Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE epsilon4 allele, in relation to cognitive function and cerebral glucose metabolism

scientific article published on 14 September 2006

Differential changes of nicotinic receptors in the rat brain following ibotenic acid and 192-IgG saporin lesions of the nucleus basalis magnocellularis

scientific article published on November 1998

Differential co-expression of nicotinic acetylcholine receptor alpha 4 and beta 2 subunit genes in various regions of rat brain

scientific article published in July 1996

Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo

scientific article

Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies.

scientific article published on 12 January 2017

Distribution of nicotinic receptors in human thalamus as visualized by 3H-nicotine and 3H-acetylcholine receptor autoradiography

scientific article published on 01 January 1988

Diurnal fluctuation in striatal choline acetyltransferase activity and strain difference in brain protein content of the rat

scientific article published on 01 April 1980

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease

scientific article published on 26 January 2016

Do tetrahydroaminoacridine (THA) and physostigmine restore acetylcholine release in Alzheimer brains via nicotinic receptors?

scientific article published on 01 January 1987

Dual effects of nicotine on oxidative stress and neuroprotection in PC12 cells.

scientific article published in August 2003

Dual tracer tau PET imaging reveals different molecular targets for C-THK5351 and C-PBB3 in the Alzheimer brain

Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease

scientific article

EEG regional changes during long-term treatment with tetrahydroaminoacridine (THA) in Alzheimer's disease

scientific article published in January 1993

Early astrocytosis in autosomal dominant Alzheimer's disease measured in vivo by multi-tracer positron emission tomography

scientific article

Early changes in Abeta levels in the brain of APPswe transgenic mice--implication on synaptic density, alpha7 neuronal nicotinic acetylcholine- and N-methyl-D-aspartate receptor levels.

scientific article published in October 2005

Early diagnosis of Alzheimer disease with positron emission tomography.

scientific article

Early warning of disturbances in a laboratory-scale MSW biogas process

scientific article published in January 2002

Effect of Alzheimer Familial Chromosomal Mutations on the Amyloid Fibril Interaction with Different PET Tracers: Insight from Molecular Modeling Studies.

scientific article published on 12 September 2017

Effect of denervation on acetylcholine synthesizing activity and nicotine-like binding sites in rat hind limb muscles

scientific article published on 01 March 1982

Effect of huprine X on β-amyloid, synaptophysin and α7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice

scientific article published on 4 August 2010

Effect of in vivo microdialysis of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on the extracellular concentration of acetylcholine in the striatum of anesthetized rats.

scientific article

Effect of long-term nicotine treatment on [3H]nicotine binding sites in the rats brain

scientific article published in September 1985

Effect of memantine on the alpha 7 neuronal nicotinic receptors, synaptophysin- and low molecular weight MAP-2 levels in the brain of transgenic mice over-expressing human acetylcholinesterase.

scientific article published on 14 September 2004

Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease

scientific article

Effect of subchronic galantamine treatment on neuronal nicotinic and muscarinic receptor subtypes in transgenic mice overexpressing human acetylcholinesterase.

scientific article published in September 2004

Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice

scientific article published on 14 December 2005

Effect of tacrine on in vivo release of dopamine and its metabolites in the striatum of freely moving rats.

scientific article

Effect of unilateral nucleus basalis lesion on cortical and striatal acetylcholine and dopamine release monitored in vivo with microdialysis

scientific article

Effects of IGF-1, truncated IGF-1 and the tripeptide Gly-Pro-Glu on acetylcholine release from parietal cortex of rat brain

scientific article published on 01 September 1993

Effects of chronic treatment with (+)- and (-)-nicotine on nicotinic acetylcholine receptors and N-methyl-D-aspartate receptors in rat brain

scientific article

Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells.

scientific article published on 15 February 2007

Electroencephalography and glucose metabolism (positron-emission tomography) in dementing disorders

scientific article

Elevated levels of Abeta1-40 and Abeta1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice.

scientific article published in August 2002

Encapsulated cell biodelivery of nerve growth factor to the Basal forebrain in patients with Alzheimer's disease

scientific article

Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains.

scientific article published on November 1995

Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.

scientific article published on January 2012

Expression of nicotinic acetylcholine receptors in human and rat adrenal medulla.

scientific article

Expression of nicotinic receptors on primary cultures of rat astrocytes and up-regulation of the alpha7, alpha4 and beta2 subunits in response to nanomolar concentrations of the beta-amyloid peptide(1-42).

scientific article published in September 2005

Expression of the alpha7, alpha4 and alpha3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and beta-amyloid

scientific article published on 30 March 2006

Extraneural cholinergic markers in Alzheimer's and Parkinson's disease.

scientific article published in January 1986

First administration of the Fc-attenuated anti-β amyloid antibody GSK933776 to patients with mild Alzheimer's disease: a randomized, placebo-controlled study

scientific article

Free Energy Profile for Penetration of Pittsburgh Compound-B into the Amyloid β Fibril

scientific article published on 11 February 2019

Functional interactions of fibrillar and oligomeric amyloid-β with alpha7 nicotinic receptors in Alzheimer's disease

scientific article published on January 2011

Functional studies of cholinergic activity in normal and Alzheimer disease states by imaging technique.

scientific article

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

scientific article published on 4 June 2013

Future prospects of research on central cholinergic mechanisms

scientific article published on January 1990

Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimer's Disease

scientific article published on 14 August 2014

Glucose metabolism and PIB binding in carriers of a His163Tyr presenilin 1 mutation

scientific article published on 30 September 2009

Harmonized diagnostic criteria for Alzheimer's disease: recommendations

scientific article

High PIB retention in Alzheimer's disease is an early event with complex relationship with CSF biomarkers and functional parameters

scientific article published in February 2010

High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques.

scientific article published in March 2005

Higher expression of alpha7 nicotinic acetylcholine receptors in human fetal compared to adult brain.

scientific article published in May 2003

Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach.

scientific article published in January 2018

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

scientific article (publication date: 21 January 2004)

Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm

scientific article published on 21 March 2016

Imaging markers for Alzheimer disease: which vs how

scientific article

Imaging of nicotinic and muscarinic receptors in Alzheimer's disease: effect of tacrine treatment

scientific article

Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography

scientific article published on November 2003

Imaging β-amyloid using [(18)F]flutemetamol positron emission tomography: from dosimetry to clinical diagnosis

scientific article published on 06 October 2015

Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment

scientific article published on March 2001

Impairment of neocortical metabolism predicts progression in Alzheimer's disease.

scientific article published in November 1999

In vitro binding of 3H-acetylcholine to nicotinic receptors in rodent and human brain

scientific article published on 01 January 1987

In vitro evaluation of 11C-labeled (S)-nicotine, (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole, and (R,S)-1-methyl-2-(3-pyridyl)azetidine as nicotinic receptor ligands for positron emission tomography studies

scientific article published in October 1998

In vivo amyloid imaging with PET in frontotemporal dementia.

scientific article published on 11 September 2007

In vivo positron emission tomography studies on the novel nicotinic receptor agonist [11C]MPA compared with [11C]ABT-418 and (S)(-)[11C]nicotine in rhesus monkeys

scientific article published on 01 August 1999

Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists

scientific article published on 01 February 2000

Increased number of muscarinic binding sites in brain following chronic barbiturate treatment to rat

scientific article published on 01 January 1980

Influence of age and gender on skin vessel reactivity to endothelium-dependent and endothelium-independent vasodilators tested with iontophoresis and a laser Doppler perfusion imager

scientific article published on March 1995

Influence of cholesterol and lovastatin on alpha-form of secreted amyloid precursor protein and expression of alpha7 nicotinic receptor on astrocytes

scientific article published on 3 May 2006

Influence of development and aging on nicotinic receptor subtypes in rodent brain

scientific article published on 01 January 1990

Influence of lipid peroxidation on the nicotinic acetylcholine receptors in PC12 cells

scientific article published in June 2000

Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

scientific article published on 29 December 2006

Insulin-like growth factor 1 (IGF-1) receptors in the human brain: quantitative autoradiographic localization

scientific article published on 01 December 1989

Insulin-like growth factor 1 stimulates the release of acetylcholine from rat cortical slices

scientific article published on 01 May 1988

Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type ⬇️

scientific article published on January 1, 1993

Interaction of a muscarinic cholinergic agonist on acetylcholine and dopamine receptors in the monkey brain studied with positron emission tomography

scientific article

Interaction of the nicotinic agonist (R,S)-3-pyridyl-1-methyl-2-(3-pyridyl)-azetidine (MPA) with nicotinic acetylcholine receptor subtypes expressed in cell lines and rat cortex

scientific article published on May 1998

Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease

scientific article published in September 1998

Intracranial infusion of purified nerve growth factor to an Alzheimer patient: the first attempt of a possible future treatment strategy

scientific article

Investigation of the Binding Profiles of AZD2184 and Thioflavin T with Amyloid-β(1-42) Fibril by Molecular Docking and Molecular Dynamics Methods.

scientific article published on 12 August 2015

Is amyloid plaque imaging the key to monitoring brain pathology of Alzheimer's disease in vivo?

scientific article published on 15 September 2004

Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains--in vivo assessment using positron emission tomography.

scientific article published on January 1995

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia.

scientific article published in July 2001

Laminar distribution of nicotinic receptor subtypes in human cerebral cortex as determined by [3H](-)nicotine, [3H]cytisine and [3H]epibatidine in vitro autoradiography

scientific article published in August 1998

Learning deficits in aged rats pretreated chronically with barbital and tested late in abstinence: alleviation by tetrahydroaminoacridine.

scientific article published in January 1990

Ligands for in vivo imaging of nicotinic receptor subtypes in Alzheimer brain.

scientific article

Long-lasting acetylcholinesterase splice variations in anticholinesterase-treated Alzheimer's disease patients.

scientific article published in March 2004

Long-term effects of galantamine treatment on brain functional activities as measured by PET in Alzheimer's disease patients.

scientific article published in January 2011

Long-term tacrine treatment in three mild Alzheimer patients: effects on nicotinic receptors, cerebral blood flow, glucose metabolism, EEG, and cognitive abilities.

scientific article published in September 1998

Long-term treatment with tacrine (THA) in Alzheimer's disease--evaluation of neuropsychological data

scientific article published on January 1993

Longitudinal PET evaluation of cerebral glucose metabolism in rivastigmine treated patients with mild Alzheimer's disease.

scientific article published on 29 July 2005

Longitudinal association between astrocyte function and glucose metabolism in autosomal dominant Alzheimer's disease

scientific article published on 04 December 2018

Longitudinal changes in quantitative EEG during long-term tacrine treatment of patients with Alzheimer's disease.

scientific article published in September 1998

Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer's disease dementia

scientific article published on 16 May 2017

Longitudinal pathways of cerebrospinal fluid and positron emission tomography biomarkers of amyloid-β positivity

scientific article published on 11 December 2020

Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer's disease

Longitudinal uncoupling of cerebral perfusion, glucose metabolism, and tau deposition in Alzheimer's disease

scientific article published on 18 December 2017

Loss of nicotinic receptors induced by beta-amyloid peptides in PC12 cells: possible mechanism involving lipid peroxidation.

scientific article published in February 2003

Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein.

scientific article published on November 2005

Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers.

scientific article published on 13 June 2012

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

scientific article

Mechanisms of alcohol-nicotine interactions: alcoholics versus smokers.

scientific article published in May 2001

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression

scientific article

Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment

scientific article published in September 2004

Modulation of dopamine release by the nicotinic agonist epibatidine in the frontal cortex and the nucleus accumbens of naive and chronic nicotine treated rats.

scientific article published in December 2004

Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine.

scholarly article

Modulation of α7 nicotinic acetylcholine receptor and fibrillar amyloid-β interactions in Alzheimer's disease brain

scientific article published in January 2013

Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development.

scientific article published on 2 December 2011

Molecular imaging in sporadic Alzheimer's disease populations and those genetically at risk.

scientific article published on 09 January 2014

Molecular imaging markers in clinical trials in Alzheimer s disease.

scientific article published in April 2009

Monitoring of a biogas process using electronic gas sensors and near-infrared spectroscopy (NIR).

scientific article published in January 2000

Multiple actions of THA on cholinergic neurotransmission in Alzheimer brains.

scientific article published on January 1989

Muscarinic and nicotinic receptor changes in the cortex and thalamus of brains of chronic alcoholics

scientific article published in August 1993

Muscarinic binding sites in small homogenates and in autoradiographic sections from rat and human spinal cord

scientific article published in May 1984

Muscarinic receptor compensation in hippocampus of Alzheimer patients

scientific article published on 01 January 1983

Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type

scientific article

Muscarinic receptor subtypes in subpopulations of human blood mononuclear cells as analyzed by RT-PCR technique

scientific article published on August 1996

Muscarinic receptors in human SH-SY5Y neuroblastoma cell line: regulation by phorbol ester and retinoic acid-induced differentiation

scientific article published on 01 June 1987

Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report).

scientific article

Neural Stem Cell Transplant-Induced Effect on Neurogenesis and Cognition in Alzheimer Tg2576 Mice Is Inhibited by Concomitant Treatment with Amyloid-Lowering or Cholinergic α7 Nicotinic Receptor Drugs

scientific article

Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures.

scientific article published on March 2007

Neuronal nicotinic and muscarinic receptor subtypes at different ages of transgenic mice overexpressing human acetylcholinesterase.

scientific article published in April 2003

Neuronal nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation

scientific article published in March 1999

Neuronal nicotinic receptors in the human brain

scientific article (publication date: May 2000)

Neuroprotection and neuroregeneration in Alzheimer's disease

scientific article

Neuroprotection in Alzheimer's disease - new strategies for treatment.

scientific article published in January 2000

Neurotrophic and neuroprotective actions of (-)- and (+)-phenserine, candidate drugs for Alzheimer's disease

scientific article

Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons

scientific article published on 3 October 2009

New approaches to clinical and postmortem investigations of cholinergic mechanisms

scientific article published on January 1990

Nicotine deposition and body distribution from a nicotine inhaler and a cigarette studied with positron emission tomography

scientific article published on 01 May 1996

Nicotine exposure during a critical period of development leads to persistent changes in nicotinic acetylcholine receptors of adult rat brain.

scientific article

Nicotine receptors in the brain of patients with Alzheimer's disease. Studies with 11C-nicotine and positron emission tomography

scientific article published on January 1, 1991

Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice.

scientific article published on May 2004

Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain.

scientific article published in January 2001

Nicotinic and muscarinic subtypes in the human brain: changes with aging and dementia

scientific article published in January 1992

Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.

scientific article

Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes

scientific article published in August 1997

No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes.

scientific article

On-line NIR monitoring during anaerobic treatment of municipal solid waste ⬇️

scientific article published on January 1, 2003

Optimal timing of tau pathology imaging and automatic extraction of a reference region using dynamic [F]THK5317 PET

scientific article published on 22 January 2019

PET imaging of amyloid deposition in patients with mild cognitive impairment

scientific article

PET imaging of amyloid in Alzheimer's disease.

scientific article

PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease

scientific article published on 11 July 2006

PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD.

scientific article published on 26 March 2007

PET studies and cholinergic therapy in Alzheimer's disease

scientific article

Pharmacodynamics of cholinesterase inhibitors suggests add-on therapy with a low-dose carbamylating inhibitor in patients on long-term treatment with rapidly reversible inhibitors.

scientific article published in January 2014

Pharmacokinetic studies of cholinesterase inhibitors

scientific article

Pharmacological treatment of cognitive dysfunction in dementia disorders.

scientific article published on January 1996

Physostigmine restores 3H-acetylcholine efflux from Alzheimer brain slices to normal level

scientific article published on 01 January 1986

Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study

scientific article published on 07 July 2016

Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study

scientific article published on 20 March 2010

Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's disease

scientific article

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects.

scientific article published on 21 November 2014

Postnatal changes of nicotinic acetylcholine receptor alpha 2, alpha 3, alpha 4, alpha 7 and beta 2 subunits genes expression in rat brain

scientific article

Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice

scientific journal article

Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics

scientific article published on 31 January 2015

Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease

scientific article published on 6 February 2013

Preface

Preserved cognitive function after 12 months of treatment with rivastigmine in mild Alzheimer's disease in comparison with untreated AD and MCI patients.

scientific article published in April 2004

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

scientific article published in May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

scientific article published on 27 March 2018

Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset

scientific article published on 02 July 2019

Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment

scientific article

Promising two-photon probes for in vivo detection of β amyloid deposits

scientific article published on 01 October 2014

Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer's disease.

scientific article published in January 2003

Quantitative autoradiography of nicotinic receptors in large cryosections of human brain hemispheres

scientific article published on 01 July 1989

Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease

scientific article

Quantitative positron emission tomography in brain research

scientific article published on 23 June 2017

Rats exhibiting acute behavioural tolerance to nicotine have more [125I]alpha-bungarotoxin binding sites in brain than rats not exhibiting tolerance.

scientific article published in August 2000

Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia

scientific article

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

scientific article

Reduced expression of neuronal nicotinic acetylcholine receptors during the early stages of damage by oxidative stress in PC12 cells

scientific article published in November 2001

Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients

scientific article published in March 2004

Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains

scientific article published in December 1986

Reduced penetrance of the PSEN1 H163Y autosomal dominant Alzheimer mutation: a 22-year follow-up study.

scientific article published on 10 May 2018

Regional brain distribution and binding of the muscarinic receptor agonist CI-979 studied by positron emission tomography in the monkey

scientific article published in September 1997

Regional deposition of inhaled 11C-nicotine vapor in the human airway as visualized by positron emission tomography

scientific article published on 01 March 1995

Regional distribution of nicotinic receptor subunit mRNAs in human brain: comparison between Alzheimer and normal brain

scientific article (publication date: 20 March 1999)

Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord

scientific article

Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (+/-)-[3H]epibatidine

scientific article published in August 1998

Regional tau deposition measured by [(18)F]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer's disease

scientific article published on 29 September 2016

Regulation of alpha 4 beta 2 nicotinic acetylcholine receptors in M10 cells following treatment with nicotinic agents.

scientific article published on January 1995

Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway

scientific article published on 14 May 2007

Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells

scientific article published on 01 May 1998

Responder characteristics to a single oral dose of cholinesterase inhibitor: a double-blind placebo-controlled study with tacrine in Alzheimer patients

scientific article

Retinoic acid and nerve growth factor induce differential regulation of nicotinic acetylcholine receptor subunit expression in SN56 cells

scientific article published on February 2007

Role of growth factors in degeneration and regeneration in the central nervous system; clinical experiences with NGF in Parkinson's and Alzheimer's diseases.

scientific article

SNMMI Procedure Standard/EANM Practice Guideline for Amyloid PET Imaging of the Brain 1.0.

scientific article published in August 2016

Safety of lumbar puncture procedures in patients with Alzheimer's disease.

scientific article

Selective changes in expression of different nicotinic receptor subtypes in brain and adrenal glands of mice carrying human mutated gene for APP or over-expressing human acetylcholinestrase.

scientific article published in November 2004

Selective changes in the levels of nicotinic acetylcholine receptor protein and of corresponding mRNA species in the brains of patients with Parkinson's disease.

scientific article

Selective decreases of nicotinic acetylcholine receptors in PC12 cells exposed to fluoride.

scientific article

Selective nicotinic receptor consequences in APP(SWE) transgenic mice.

scientific article published in June 2002

Skin vessel reactivity is impaired in Alzheimer's disease

scientific article published on 01 July 1995

Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum

scientific article published in January 2005

Smoking during pregnancy: a way to transfer the addiction to the next generation?

scientific article

Spatial Normalization of 18F-Flutemetamol PET Images Using an Adaptive Principal-Component Template

scientific article published on 14 June 2018

Spatial pattern of cerebral glucose metabolism (PET) correlates with localization of intracerebral EEG-generators in Alzheimer's disease.

scientific article published in October 2000

Steady-state pharmacokinetics of tacrine in long-term treatment of Alzheimer patients.

scientific article published in March 1996

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

scientific article

Subchronic treatment of rats with nicotine: effects on tolerance and on [3H]acetylcholine and [3H]nicotine binding in the brain

scientific article published in May 1986

Substance P-like immunoreactivity, choline acetyltransferase activity and cholinergic muscarinic receptors in Alzheimer's disease and multi-infarct dementia ⬇️

scientific article published on June 25, 1990

Suppressed expression of nicotinic acetylcholine receptors by nanomolar beta-amyloid peptides in PC12 cells.

scientific article published in January 2001

Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months

scientific article published in August 2002

Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease

scientific article published in April 2008

Synthesis and characterization of binding of 5-[76Br]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain

scientific article published in September 1999

Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells.

scientific article published in May 1998

Tacrine interacts with an allosteric activator site on alpha 4 beta 2 nAChRs in M10 cells

scientific article published on September 1996

Tacrine restores cholinergic nicotinic receptors and glucose metabolism in Alzheimer patients as visualized by positron emission tomography

scientific article published on November 1, 1992

Target-specific PET probes for neurodegenerative disorders related to dementia

scientific article published on September 2010

Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device

scientific article published on 07 July 2016

Tau PET imaging in neurodegenerative tauopathies-still a challenge

scientific article published on 11 January 2019

Tau PET imaging: present and future directions

scientific article

Tau positron emission tomography imaging in tauopathies: The added hurdle of off-target binding.

scientific article published in 2018

Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences ⬇️

scientific article published on August 1, 1991

Tetrahydroaminoacridine induces opposite changes in muscarinic and nicotinic receptors in rat brain

scientific article published in September 1990

The Culprit Is in the Cave: The Core Sites Explain the Binding Profiles of Amyloid-Specific Tracers

scientific article

The alpha7 nicotinic receptors in human fetal brain and spinal cord

scientific article published in February 2002

The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase

scientific article published on 26 August 2009

The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the path

scientific article published on 8 April 2007

The contribution of small vessel disease to subtypes of Alzheimer's disease: a study on cerebrospinal fluid and imaging biomarkers

scientific article published on 30 May 2018

The future: new methods of imaging exploration in Alzheimer's disease.

scientific article published on 26 January 2009

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease

scholarly article by Daniel Twohig et al published 26 November 2018 in Acta neuropathologica communications

The risk of exaggerated risk aversion-a life and death struggle for molecular imaging

scientific article published on October 2009

The role of nicotinic receptors in the pathophysiology of Alzheimer's disease

scientific article published on January 1989

The use of PET in Alzheimer disease

scientific article published on February 2010

The use of PIB-PET as a dual pathological and functional biomarker in AD.

scientific article published on 13 November 2011

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey

scientific article published on 20 August 2014

Theoretical study of the binding profile of an allosteric modulator NS-1738 with a chimera structure of the α7 nicotinic acetylcholine receptor

scientific article published on 30 September 2016

Time course of glucose metabolism in relation to cognitive performance and postmortem neuropathology in Met146Val PSEN1 mutation carriers.

scientific article published in January 2011

Tolerance, physical dependence and changes in muscarinic receptor binding sites after chronic ethanol treatment in the rat

scientific article published on 01 July 1982

Topographic distribution of choline acetyltransferase activity and muscarinic and nicotinic receptors in Parkinson brains

scientific article

Tracer Kinetic Analysis of (S)-¹⁸F-THK5117 as a PET Tracer for Assessing Tau Pathology.

scientific article

Transgenic mice as a model for Alzheimer's disease

scientific article published on December 2011

Transgenic mice overexpressing human acetylcholinesterase and the Swedish amyloid precursor protein mutation: effect of nicotine treatment.

scientific article published in March 2008

Treatment of Alzheimer disease with tacrine: a cost-analysis model.

scientific article published in December 1997

Two-year follow-up of amyloid deposition in patients with Alzheimer's disease

scientific article published on 19 July 2006

Unidirectional Influx and Net Accumulation of PIB

scientific article

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice

scientific article published in May 2002

Upregulation of neuronal nicotinic receptor subunits alpha4, beta2, and alpha7 in transgenic mice overexpressing human acetylcholinesterase.

scientific article

Uptake and regional distribution of (+)-(R)- and (-)-(S)-N-[methyl-11C]-nicotine in the brains of rhesus monkey. An attempt to study nicotinic receptors in vivo

scientific article published in January 1989

Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study

scientific article published on 14 October 2015

Use of carbon-11 nicotine in PET studies

scientific article published in July 1997

Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

scientific article published on 2 July 2015

[(11)C]-PIB imaging in patients with Parkinson's disease: preliminary results.

scientific article

[(11)C]PIB-amyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients

scientific article published on 30 December 2008

[18F]THK5317 imaging as a tool for predicting prospective cognitive decline in Alzheimer's disease

scientific article published on 03 July 2020

[3H]acetylcholine nicotinic recognition sites in human brain: characterization of agonist binding

scientific article

[Administration of symptom-relieving drugs in Alzheimer disease is beneficial]

scientific article published on 01 February 2006

[Don't underestimate the value of transgenic animal models of Alzheimer disease].

scientific article published in March 2007

[More accurate diagnosis could identify patients suitable for tacrine therapy]

scientific article published on 01 March 1996

[New studies on Alzheimer's disease. Promising therapeutic results with tacrine]

scientific article published on 01 April 1993

³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain

scientific article

Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons

scientific article (publication date: 17 December 2010)

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