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List of works by Kenneth W Mahaffey

2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials

scholarly article by Karen A. Hicks et al published July 2015 in Journal of the American College of Cardiology

2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Cardi

scientific article

2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways

scientific article published on 10 November 2017

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials

scientific article published in February 2018

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials

scientific article published in March 2018

5-year results of a randomized comparison of XIENCE V everolimus-eluting and TAXUS paclitaxel-eluting stents: final results from the SPIRIT III trial (clinical evaluation of the XIENCE V everolimus eluting coronary stent system in the treatment of p

scientific article

A 15-year review of the Stanford Internal Medicine Residency Program: predictors of resident satisfaction and dissatisfaction

scientific article

A comparison of the clinical impact of bleeding measured by two different classifications among patients with acute coronary syndromes

scientific article published on 26 January 2006

A novel approach to systematically implement the universal definition of myocardial infarction: insights from the CHAMPION PLATFORM trial

scientific article published on 23 February 2013

A perspective on trials comparing enoxaparin and unfractionated heparin in the treatment of non-ST-elevation acute coronary syndromes

scientific article published in April 2005

A subgroup analysis of the impact of prerandomization antithrombin therapy on outcomes in the SYNERGY trial: enoxaparin versus unfractionated heparin in non-ST-segment elevation acute coronary syndromes

scientific article published on 12 September 2006

A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes

scientific article

ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use.

scientific article published on 03 October 2008

ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents

scientific article

Absence of Oral Anticoagulation and Subsequent Outcomes Among Outpatients with Atrial Fibrillation

scientific article published on 22 November 2016

Academic health centers: integration of clinical research with healthcare and education. Comments on a workshop

article

Activated partial thromboplastin time measurement is not associated with clinical outcomes in patients with high-risk non-ST-segment elevation acute coronary syndromes treated with unfractionated heparin ⬇️

scientific article published on July 1, 2012

Acute coronary syndromes: what have we learned about what we still need to know?

scientific article

Adjuvant Antithrombotic Therapy in TAVR.

scientific article published on May 2017

Albuminuria and cardiovascular events in patients with acute coronary syndromes: Results from the TRACER trial

scientific article published on 27 April 2016

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

article

Alternative calculations of individual patient time in therapeutic range while taking warfarin: results from the ROCKET AF trial

scientific article

An examination of the relationship between serum uric acid level, a clinical history of gout, and cardiovascular outcomes among patients with acute coronary syndrome

scientific article published on 21 February 2017

Anticoagulant and antiplatelet therapy choices for patients with atrial fibrillation one year after coronary stenting or acute coronary syndrome

scientific article published on 24 January 2018

Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients

scientific article published on October 2012

Arterial access site and outcomes in patients undergoing percutaneous coronary intervention with and without vorapaxar

scientific article published on 23 December 2015

Assessing the treatment effect in a randomized controlled trial with extensive non-adherence: the EVOLVE trial

scientific article published on 6 April 2015

Association Between Atrial Fibrillation Symptoms, Quality of Life, and Patient Outcomes: Results From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

scientific article published on 9 June 2015

Association of Body Mass Index With Care and Outcomes in Patients With Atrial Fibrillation

Association of Multiple Biomarkers With Risk of All-Cause and Cause-Specific Mortality After Acute Coronary Syndromes: A Secondary Analysis of the PLATO Biomarker Study

scientific article published on 01 December 2018

Association of Myocardial Enzyme Elevation and Survival Following Coronary Artery Bypass Graft Surgery ⬇️

scientific article published on February 9, 2011

Association of aspirin dose and vorapaxar safety and efficacy in patients with non-ST-segment elevation acute coronary syndrome (from the TRACER Trial).

scientific article published on 25 December 2013

Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial

scientific article published on 18 January 2012

Atrial fibrillation: a spectrum of risk with a uniform treatment effect of novel anticoagulants? ⬇️

scientific article published on June 13, 2013

Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial

scientific article published in July 2012

Baseline Q-wave surpasses time from symptom onset as a prognostic marker in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention

scientific article

Baseline characteristics of subjects enrolled in the Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) trial

scientific article published on 23 April 2012

Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibi

scientific article published on 29 October 2013

Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal

scientific article published in January 2007

Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial

scientific article published on 16 November 2011

Blood pressure control and stroke or bleeding risk in anticoagulated patients with atrial fibrillation: Results from the ROCKET AF Trial

scientific article published on 6 May 2016

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

scientific article published on 12 June 2017

Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study).

scientific article published on 11 March 2018

Canagliflozin review – safety and efficacy profile in patients with T2DM

article

Cangrelor Versus Clopidogrel on a Background of Unfractionated Heparin (from CHAMPION PHOENIX).

scientific article

Cangrelor With and Without Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention

scientific article published in January 2017

Cangrelor compared with clopidogrel in patients with prior myocardial infarction - Insights from the CHAMPION trials

scientific article

Cangrelor in Older Patients Undergoing Percutaneous Coronary Intervention: Findings From CHAMPION PHOENIX.

scientific article

Cangrelor reduces the risk of ischemic complications in patients with single-vessel and multi-vessel disease undergoing percutaneous coronary intervention: Insights from the CHAMPION PHOENIX trial

scientific article published on 6 March 2017

Cardiac troponin after percutaneous coronary intervention and 1-year mortality in non-ST-segment elevation acute coronary syndrome using systematic evaluation of biomarker trends

scientific article published on 15 May 2013

Cardiogenic shock and heart failure post-percutaneous coronary intervention in ST-elevation myocardial infarction: observations from "Assessment of Pexelizumab in Acute Myocardial Infarction".

scientific article published on July 2011

Cardiovascular Outcomes After Lower Extremity Endovascular or Surgical Revascularization: The EUCLID Trial

scientific article published on 01 October 2018

Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial

scientific article

Cardioversion and subsequent quality of life and natural history of atrial fibrillation

scientific article

Care Patterns and Outcomes in Atrial Fibrillation Patients With and Without Diabetes: ORBIT-AF Registry.

scientific article published in September 2017

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

scientific article

Causes of mortality with ticagrelor compared with clopidogrel in acute coronary syndromes

scientific article published on 23 June 2014

Centralized adjudication of cardiovascular end points in cardiovascular and noncardiovascular pharmacologic trials: a report from the Cardiac Safety Research Consortium

scientific article published on 10 November 2014

Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial

scientific article published on 07 November 2018

Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes

scientific article published on June 2005

Cinacalcet, Fibroblast Growth Factor-23, and Cardiovascular Disease in Hemodialysis: The Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial

scientific article published on 09 June 2015

Cinacalcet, dialysate calcium concentration, and cardiovascular events in the EVOLVE trial

scientific article published on 13 November 2015

Clinical Characteristics, Oral Anticoagulation Patterns, and Outcomes of Medicaid Patients With Atrial Fibrillation: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF I) Registry

scientific article published on 04 May 2016

Clinical Outcomes With Rivaroxaban in Patients Transitioned From Vitamin K Antagonist Therapy

article

Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial

scientific article

Clinical features and outcomes of patients with type 2 myocardial infarction: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial

scientific article published on 16 October 2017

Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention

scientific article (publication date: 1999)

Clinical use of enoxaparin in the management of non-ST segment elevation acute coronary syndromes

scientific article

Clopidogrel and PPI Interaction: Clinically Relevant or Not? ⬇️

scientific article published on February 1, 2012

Comparing classifications of death in the Mode Selection Trial: agreement and disagreement among site investigators and a clinical events committee

scientific article

Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial

scientific article published on April 2008

Comparison of clinical trial outcome patterns in patients following acute coronary syndromes and in patients with chronic stable atherosclerosis.

scientific article

Comparison of site-reported and core laboratory-reported creatine kinase-MB values in non-ST-segment elevation acute coronary syndrome (from the international trial SYNERGY).

scientific article published on 25 September 2009

Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction.

scientific article

Concerning the mechanism of pexelizumab's benefit in acute myocardial infarction

Consistent Reduction in Periprocedural Myocardial Infarction With Cangrelor as Assessed by Multiple Definitions: Findings From CHAMPION PHOENIX (Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition).

scientific article published on August 2016

Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: design and rationale of the SYNERGY Library

scientific article

Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predict

scientific article published on 21 February 2008

Creatine kinase-MB elevation after coronary artery bypass grafting surgery in patients with non-ST-segment elevation acute coronary syndromes predict worse outcomes: results from four large clinical trials

scientific article

Current perspectives on reperfusion therapy for acute ST-segment elevation myocardial infarction: integrating pharmacologic and mechanical reperfusion strategies

scientific article (publication date: December 2003)

Cytokines profile in hypertensive patients with left ventricular remodeling and dysfunction

scientific article published on 17 October 2015

Data monitoring committees: Promoting best practices to address emerging challenges

scientific article

Design and rationale for the Effects of Ticagrelor and Clopidogrel in Patients with Peripheral Artery Disease (EUCLID) trial

scientific article

Determinants of plasma vitamin D levels in patients with acute coronary syndromes ⬇️

scientific article published on May 25, 2011

Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome

scientific article

Digoxin Use and Subsequent Outcomes Among Patients in a Contemporary Atrial Fibrillation Cohort

scientific article published on June 2015

Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Tr

scientific article

Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study

scientific article

Disease understanding in patients newly diagnosed with atrial fibrillation

scientific article

Drivers of hospitalization for patients with atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)

scientific article

Dynamic modeling of 90-day mortality in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

scientific article published on 15 January 2013

Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation

scientific article

Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

scientific article published in November 2018

Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF]).

scientific article published on 16 March 2017

Effect of Cinacalcet on Cardiovascular Disease in Patients Undergoing Dialysis ⬇️

scientific article published on November 3, 2012

Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial

scientific article published on 9 June 2016

Effect of alirocumab, a monoclonal antibody to PCSK9, on long-term cardiovascular outcomes following acute coronary syndromes: rationale and design of the ODYSSEY outcomes trial

scientific article published on 7 August 2014

Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data

scientific article

Effect of pexelizumab on mortality in patients with acute myocardial infarction or undergoing coronary artery bypass surgery: A systematic overview

Effect of pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction: the COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial

scientific article published on 18 August 2003

Effect of platelet inhibition with cangrelor during PCI on ischemic events

scientific article

Effect of vorapaxar on myocardial infarction in the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome (TRA·CER) trial

scientific article published on 25 March 2013

Effects of Cinacalcet on Fracture Events in Patients Receiving Hemodialysis: The EVOLVE Trial

scientific article published on 11 December 2014

Effects of cinacalcet on atherosclerotic and nonatherosclerotic cardiovascular events in patients receiving hemodialysis: the EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) trial

scientific article

Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial

scientific article published on 21 July 2018

Efficacy and Safety of Canagliflozin Used in Conjunction with Sulfonylurea in Patients with Type 2 Diabetes Mellitus: A Randomized, Controlled Trial

scientific article published on 17 June 2015

Efficacy and Safety of Cangrelor in Preventing Periprocedural Complications in Patients With Stable Angina and Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: The CHAMPION PHOENIX Trial.

scientific article

Efficacy and Safety of Cangrelor in Women Versus Men During Percutaneous Coronary Intervention: Insights From the Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION PHOENIX) Trial

scientific article published on 13 January 2016

Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial).

scientific article

Efficacy and Safety of Rivaroxaban versus Warfarin in Patients with Nonvalvular Atrial Fibrillation and a History of Cancer: Observations from ROCKET AF

article by Sean T Chen et al published 14 September 2018 in European heart journal. Quality of care & clinical outcomes

Efficacy and Safety of Vorapaxar in Non-ST-Segment Elevation Acute Coronary Syndrome Patients Undergoing Noncardiac Surgery

scientific article published on 15 December 2015

Efficacy and bleeding complications among patients randomized to enoxaparin or unfractionated heparin for antithrombin therapy in non-ST-Segment elevation acute coronary syndromes: a systematic overview

scientific article published in July 2004

Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes

scientific article

Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin,

scientific article published in December 2006

Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Em

scientific article

Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF.

scientific article

Efficacy and safety of rivaroxaban in patients with diabetes and nonvalvular atrial fibrillation: The Rivaroxaban Once-daily, Oral, Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial F

article by Sameer Bansilal et al published October 2015 in American Heart Journal

Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF.

scientific article published on 30 May 2013

Efficacy and safety of rivaroxaban versus warfarin in patients from mainland China with nonvalvular atrial fibrillation: A subgroup analysis from the ROCKET AF trial

scientific article published on 13 April 2017

Efficacy and safety of the low-molecular weight heparin enoxaparin compared with unfractionated heparin across the acute coronary syndrome spectrum: a meta-analysis

scientific article published on 28 June 2007

Electrocardiographic infarct size assessment after thrombolysis: insights from the Acute Myocardial Infarction STudy ADenosine (AMISTAD) trial

scientific article

Elevated creatine kinase-MB with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: results from 4 large clinical trials

scientific article published in January 2006

End of study transition from study drug to open-label vitamin K antagonist therapy: the ROCKET AF experience

scientific article

Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: a subgroup analysis from the SYNERGY trial

scientific article published in May 2010

Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial

scientific article

Enzyme estimates of infarct size correlate with functional and clinical outcomes in the setting of ST-segment elevation myocardial infarction

scientific article

Evaluation of Cinacalcet Therapy to Lower Cardiovascular Events (EVOLVE): rationale and design overview

scientific article published on 16 August 2007

Evaluation of Ischemic and Bleeding Risks Associated With 2 Parenteral Antiplatelet Strategies Comparing Cangrelor With Glycoprotein IIb/IIIa Inhibitors: An Exploratory Analysis From the CHAMPION Trials

scientific article

Evaluation of a novel point-of-care enoxaparin monitor with central laboratory anti-Xa levels

scientific article published in January 2003

Experience with glycoprotein IIb/IIIa antagonists in patients with acute coronary syndromes

scientific article

Exploring the role of enoxaparin in the management of high-risk patients with non-ST-elevation acute coronary syndromes: the SYNERGY trial

scientific article (publication date: April 2005)

External validation of the TIMI risk score for secondary cardiovascular events among patients with recent myocardial infarction

scientific article published on 16 March 2018

Factors Contributing to the Lower Mortality With Ticagrelor Compared With Clopidogrel in Patients Undergoing Coronary Artery Bypass Surgery

article

Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation).

scientific article

Factors associated with non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II).

scientific article

Family history of atrial fibrillation is associated with earlier-onset and more symptomatic atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

scientific article

Forecasting mortality: dynamic assessment of risk in ST-segment elevation acute myocardial infarction

scientific article published on 11 January 2006

Fourth universal definition of myocardial infarction (2018)

article by Kristian Thygesen et al published 25 August 2018 in European Heart Journal

Frequency and Outcomes of Reduced Dose Non-Vitamin K Antagonist Anticoagulants: Results From ORBIT-AF II (The Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II).

scientific article published on 16 February 2018

Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials

scientific article published on 01 February 2019

Gastrointestinal Bleeding in Patients With Atrial Fibrillation Treated With Rivaroxaban or Warfarin: ROCKET AF Trial.

scientific article

Gastrointestinal ulcers, role of aspirin, and clinical outcomes: pathobiology, diagnosis, and treatment

scientific article

Glycoprotein IIb/IIIa Receptor Inhibitors in Combination With Vorapaxar, a Platelet Thrombin Receptor Antagonist, Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes (from the TRACER Trial).

scientific article published on 18 February 2015

Grade III ischemia on presentation with acute myocardial infarction predicts rapid progression of necrosis and less myocardial salvage with thrombolysis

scientific article

Guía de práctica clínica de la ESC para el manejo del infarto agudo de miocardio en pacientes con elevación del segmento ST

Heart failure complicating non-ST-segment elevation acute coronary syndrome: timing, predictors, and clinical outcomes

scientific article

Heart failure on admission and the risk of stroke following acute myocardial infarction: the VALIANT registry

scientific article published on 21 June 2005

Heart rate is associated with progression of atrial fibrillation, independent of rhythm

scientific article published on 2 March 2015

Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome ⬇️

scientific article published on February 1, 2011

High-degree atrioventricular block, asystole, and electro-mechanical dissociation complicating non-ST-segment elevation myocardial infarction

scientific article

High-risk patients with acute coronary syndromes treated with low-molecular-weight or unfractionated heparin: outcomes at 6 months and 1 year in the SYNERGY trial

scientific article

Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial

scientific article

Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil

scientific article published in August 2011

Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil

scientific article published in July 2013

Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF

scientific article published on 12 May 2016

How well does physician risk assessment predict stroke and bleeding in atrial fibrillation? Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

scientific article published on 27 August 2016

Impact of Cerebrovascular Events Older Than One Year on Ischemic and Bleeding Outcomes With Cangrelor in Percutaneous Coronary Intervention

scientific article published in January 2017

Impact of Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention

article

Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes

scientific article published on 12 September 2005

Impact of cangrelor overdosing on bleeding complications in patients undergoing percutaneous coronary intervention: insights from the CHAMPION trials

scientific article published on 30 May 2015

Impact of global geographic region on time in therapeutic range on warfarin anticoagulant therapy: data from the ROCKET AF clinical trial

scientific article

Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation-Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

scientific article published on 7 February 2015

Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV).

scientific article published on 2 July 2008

Impact of polyvascular disease on patients with atrial fibrillation: Insights from ROCKET AF

article by Sean T. Chen et al published June 2018 in American Heart Journal

Implications of different criteria for percutaneous coronary intervention-related myocardial infarction on study results of three large phase III clinical trials: The CHAMPION experience

scientific article published on 2 August 2016

Incidence and characteristics of stroke during 90-day follow-up in patients stabilized after an acute coronary syndrome

scientific article (publication date: September 2004)

Incidence, Predictors, and Outcomes of Acquired Thrombocytopenia After Percutaneous Coronary Intervention: A Pooled, Patient-Level Analysis of the CHAMPION Trials (Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibitio

scientific article published in April 2018

Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome

scientific article published on 28 March 2018

Incorporation of bleeding as an element of the composite end point in clinical trials of antithrombotic therapies in patients with non–ST-segment elevation acute coronary syndrome: Validity, pitfalls, and future approaches ⬇️

scientific article published on February 13, 2013

Increased Heart Rate Is Associated With Higher Mortality in Patients With Atrial Fibrillation (AF): Results From the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF)

scientific article

Independent data monitoring committees: preparing a path for the future

scientific article

Inference on treatment effects from a randomized clinical trial in the presence of premature treatment discontinuation: the SYNERGY trial ⬇️

scientific article published on August 25, 2010

Influence of Kidney Function Estimation Methods on Eligibility for Edoxaban Population Impact of the US Food and Drug Administration's Approach for Its Product Labeling

scientific article

Influence of body mass index on the efficacy of revascularization in patients with coronary artery disease

scientific article published on 04 March 2009

Influence of clinical trial participation on subsequent antithrombin use.

scientific article published in March 2010

Integrating ancillary studies in a large clinical trial: the design and rationale of the APEX library

scientific article

Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes

scientific article published on January 2004

International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Commi

scholarly article

International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries

scientific article published on 24 August 2017

Intracranial Hemorrhage Among Patients With Atrial Fibrillation Anticoagulated With Warfarin or Rivaroxaban

article

Intravenous platelet blockade with cangrelor during PCI.

scientific article published in December 2009

Investigator-Reported Bleeding Versus Post Hoc Adjudication of Bleeding

Ischaemic Events and Stent Thrombosis following Planned Discontinuation of Study Treatment with Ticagrelor or Clopidogrel in the PLATO Study

scientific article published on 29 January 2018

Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial

scientific article published on 15 October 2013

Lack of Concordance Between Local Investigators, Angiographic Core Laboratory, and Clinical Event Committee in the Assessment of Stent Thrombosis: Results From the TRACER Angiographic Substudy

scientific article published on May 2016

Lack of concordance between empirical scores and physician assessments of stroke and bleeding risk in atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

scientific article

Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes.

scientific article

Lessons Learned from EVOLVE for Planning of Future Randomized Trials in Patients on Dialysis

scientific article published on 27 November 2015

Letter by Matthews et al Regarding Article, "Class Effect for Sodium Glucose-Cotransporter-2 Inhibitors in Cardiovascular Outcomes: Implications for the Cardiovascular Disease Specialist"

scientific article published on 01 August 2018

Long-term outcomes associated with hospital acquired thrombocytopenia among patients with non-ST-segment elevation acute coronary syndrome

scientific article

Lost to Follow-up and Withdrawal of Consent in Contemporary Global Cardiovascular Randomized Clinical Trials

scientific article published on December 2015

Low-molecular-weight heparin compared with unfractionated heparin for patients with non-ST-segment elevation acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE initiative

scientific article published in June 2006

Magnitude of troponin elevation and long-term clinical outcomes in acute coronary syndrome patients treated with and without revascularization

scientific article published on June 2015

Management and outcomes of patients with atrial fibrillation and a history of cancer: the ORBIT-AF registry

scientific article published on July 2017

Management of Major Bleeding in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants Compared With Warfarin in Clinical Practice (from Phase II of the Outcomes Registry for Better Informed Treatment of Atrial F

scientific article published on 28 March 2017

Management of Patients With NSTE-ACS: A Comparison of the Recent AHA/ACC and ESC Guidelines

scientific article

Management of acute coronary syndromes in patients with renal dysfunction

scientific article published on July 2008

Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial

scientific article

Mechanical complications after percutaneous coronary intervention in ST-elevation myocardial infarction (from APEX-AMI).

scientific article published in January 2010

Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes

scientific article

Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: study design and conduct

scientific article

Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy

scientific article published on 2 May 2013

Mineralocorticoid Receptor Antagonism in Patients With Atrial Fibrillation: Findings From the ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) Registry

scientific article published on 13 April 2018

Misreporting of myocardial infarction end points: results of adjudication by a central clinical events committee in the PARAGON-B trial. Second Platelet IIb/IIIa Antagonist for the Reduction of Acute Coronary Syndrome Events in a Global Organization

scientific article

Mode of Death and Hospitalization from the Second Follow-Up Serial Infusions of Nesiritide (FUSION II) Trial and Comparison of Clinical Events Committee Adjudicated Versus Investigator Reported Outcomes ⬇️

scientific article published on September 3, 2011

Mortality implications of primary percutaneous coronary intervention treatment delays: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction trial

scientific article published on 08 February 2011

N-terminal pro-brain natriuretic peptide and the timing, extent and mortality in ST elevation myocardial infarction

scientific article published on April 2006

Native valve disease in patients with non-valvular atrial fibrillation on warfarin or rivaroxaban

scientific article published on 17 February 2016

Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference

scientific article

Net clinical benefit of rivaroxaban compared with warfarin in atrial fibrillation: Results from ROCKET AF.

scientific article published in April 2018

Noncentral Nervous System Systemic Embolism in Patients With Atrial Fibrillation: Results From ROCKET AF (Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atr

scientific article published in May 2017

North American Thrombosis Forum, AF Action Initiative Consensus Document

scientific article published on May 2016

Obesity in patients with non-ST-segment elevation acute coronary syndromes: results from the SYNERGY trial

scientific article

Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites

scientific article published on 7 April 2017

Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry

scientific article published on December 2016

On-Treatment Outcomes in Patients With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF.

scientific article published on July 2016

Optimizing the analysis strategy for the CANVAS Program: A prespecified plan for the integrated analyses of the CANVAS and CANVAS-R trials

scientific article published on 28 February 2017

Oral anticoagulation management in patients with atrial fibrillation undergoing cardiac implantable electronic device implantation

scientific article published on 19 May 2017

Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation

scientific article

Outcome of Patients Receiving Thrombolytic Therapy While on Rivaroxaban for Nonvalvular Atrial Fibrillation (from Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial i

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II: rationale and design of the ORBIT-AF II registry

scientific article

Outcomes after cardioversion and atrial fibrillation ablation in patients treated with rivaroxaban and warfarin in the ROCKET AF trial

scientific article published on 14 March 2013

Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial

scientific article published on 2 June 2008

Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial

scientific article published on 19 December 2017

Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Preven

scientific article published on February 2013

Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention o

scientific article

Outcomes registry for better informed treatment of atrial fibrillation: rationale and design of ORBIT-AF.

scientific article published in October 2011

Outcomes with cangrelor versus clopidogrel on a background of bivalirudin: insights from the CHAMPION PHOENIX (A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention [PCI]).

scientific article published on 18 February 2015

Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapy

scientific article published on 26 November 2007

Patients' time in therapeutic range on warfarin among US patients with atrial fibrillation: Results from ORBIT-AF registry

scientific article published on April 2015

Pattern of liver enzyme elevations in acute ST-elevation myocardial infarction.

scientific article

Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: A pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY ⬇️

scientific article published on December 1, 2010

Pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to primary percutaneous coronary intervention in acute myocardial infarction: the COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial

scientific article published on 18 August 2003

Pharmacotherapy for Atrial Fibrillation in Patients With Chronic Kidney Disease: Insights From ORBIT-AF

scientific article published on 01 September 2018

Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

scientific article

Platelet glycoprotein IIb/IIIa receptor antagonists in non-ST segment elevation acute coronary syndromes: a review and guide to patient selection

scientific article

Platelet inhibition with cangrelor in patients undergoing PCI.

scientific article published in December 2009

Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation

scientific article published on 16 December 2015

Polyvascular Disease and Risk of Major Adverse Cardiovascular Events in Peripheral Artery Disease: A Secondary Analysis of the EUCLID Trial

Pooled analysis of adverse event collection from 4 acute coronary syndrome trials

scientific article

Post-Discharge Bleeding and Mortality Following Acute Coronary Syndromes With or Without PCI

scientific article published on 01 July 2020

Predicting the risk of bleeding during dual antiplatelet therapy after acute coronary syndromes

scientific article published on 05 April 2017

Prediction of enzymatic infarct size in ST-segment elevation myocardial infarction

scientific article published on March 2012

Prediction of one-year survival in high-risk patients with acute coronary syndromes: results from the SYNERGY trial

scientific article published on 15 January 2008

Predictors and Prognostic Implications of Incident Heart Failure in Patients With Prevalent Atrial Fibrillation

scientific article

Prevalence, Characteristics, and Outcomes of Valvular Heart Disease in Patients With Atrial Fibrillation: Insights From the ORBIT-AF (Outcomes Registry for Better Informed Treatment for Atrial Fibrillation).

scientific article published on 22 December 2017

Prevalence, predictors, and impact of conservative medical management for patients with non-ST-segment elevation acute coronary syndromes who have angiographically documented significant coronary disease.

scientific article

Prognostic Significance of Bleeding Location and Severity Among Patients With Acute Coronary Syndromes ⬇️

scientific article published on July 1, 2013

Prognostic and Practical Validation of Current Definitions of Myocardial Infarction Associated With Percutaneous Coronary Intervention.

scientific article

Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention

scientific article published on 9 June 2014

Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study

scientific article

Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes

scientific article

Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy

scientific article published on 8 February 2013

Prognostic significance of blood markers of inflammation in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty and effects of pexelizumab, a C5 inhibitor: a substudy of the COMMA trial

article by Pierre Théroux et al published 4 May 2005 in European Heart Journal

Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction: results from the CARDINAL study

article by Abhinav Goyal et al published 12 April 2006 in European Heart Journal

Prognostic usefulness of white blood cell count and temperature in acute myocardial infarction (from the CARDINAL Trial).

scientific article

Prognostic utility of quantifying evolutionary ST-segment depression on early follow-up electrocardiogram in patients with non-ST-segment elevation acute coronary syndromes.

scientific article published on 23 December 2009

Promise of combined low-molecular-weight heparin and platelet glycoprotein IIb/IIIa inhibition: results from Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organization Network B (PARAGON B).

scientific article published on December 2002

Promise of factor Xa inhibition in atrial fibrillation

scientific article published on February 2012

Promises of PAR-1 inhibition in acute coronary syndrome

scientific article published on February 2012

Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry

scientific article published on 18 July 2013

Publication or presentation of results from multicenter clinical trials: evidence from an academic medical center

scientific article published on April 2007

Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: insights from the CHAMPION percutaneous coronary intervention trial

scientific article

Racial Differences Among High-Risk Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from the SYNERGY Trial)††Disclosure: Drs. Mahaffey, Cohen, Newby, Ferguson, and Califf have received honoria for speaking fro

article

Racial Differences in Quality of Anticoagulation Therapy for Atrial Fibrillation (from the TREAT-AF Study).

scientific article published on 22 October 2015

Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: Insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry

scientific article

Rate versus rhythm control for management of atrial fibrillation in clinical practice: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

scientific article

Rationale and design of a large-scale, app-based study to identify cardiac arrhythmias using a smartwatch: The Apple Heart Study

scientific article published on 08 September 2018

Rationale and design of the Cangrelor versus standard therapy to acHieve optimal Management of Platelet InhibitiON PHOENIX trial

article

Rationale and strategies for implementing community-based transfer protocols for primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction

scientific article published on June 2004

Rationale, design and baseline characteristics of the CANagliflozin cardioVascular Assessment Study-Renal (CANVAS-R): A randomized, placebo-controlled trial

scientific article published on 25 January 2017

Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS)--a randomized placebo-controlled trial

scientific article published on 24 June 2013

Reasons for warfarin discontinuation in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

scientific article published on 11 July 2014

Reduced immediate ischemic events with cangrelor in PCI: a pooled analysis of the CHAMPION trials using the universal definition of myocardial infarction

scientific article published in February 2012

Reduction in overall occurrences of ischemic events with vorapaxar: results from TRACER.

scientific article

Relation of Post-Coronary Artery Bypass Graft Creatine Kinase-MB Elevations and New Q Waves With Long-Term Cardiovascular Death in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

scientific article published on 30 August 2016

Relation of Risk of Stroke in Patients With Atrial Fibrillation to Body Mass Index (from Patients Treated With Rivaroxaban and Warfarin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention o

Relationship between renal function and outcomes in high-risk patients with non-ST-segment elevation acute coronary syndromes: results from SYNERGY.

scientific article published on 5 May 2009

Relationship between time in therapeutic range and comparative treatment effect of rivaroxaban and warfarin: results from the ROCKET AF trial

scientific article

Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin

scientific article published on 03 December 2012

Resolution of ST-segment depression: A new prognostic marker in ST-segment elevation myocardial infarction

scientific article published in December 2009

Response by Piccini et al to Letters Regarding Article, "Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation".

scientific article published in July 2016

Response to Letter Regarding Article, “Renal Dysfunction as a Predictor of Stroke and Systemic Embolism in Patients With Nonvalvular Atrial Fibrillation: Validation of the R 2 CHADS 2 Index in the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Fac

article by Jonathan P Piccini et al published 10 September 2013 in Circulation

Response to letter regarding article, "Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial".

scientific article

Results of a curtailed randomized controlled trial, evaluating the efficacy and safety of azimilide in patients with implantable cardioverter-defibrillators: The SHIELD-2 trial

scientific article

Results of a reevaluation of cardiovascular outcomes in the RECORD trial

scientific article

Review of the accumulated PLATO documentation supports reliable and consistent superiority of ticagrelor over clopidogrel in patients with acute coronary syndrome: Commentary on: DiNicolantonio JJ, Tomek A, Inactivations, deletions, non-adjudication

scientific article

Reviewing the role of healthy volunteer studies in drug development

article

Rhythm Control Versus Rate Control and Clinical Outcomes in Patients With Atrial Fibrillation

Risk factors for intracranial hemorrhage and nonhemorrhagic stroke after fibrinolytic therapy (from the GUSTO-i trial).

scientific article published in February 2004

Risks and Benefits of Anticoagulation in Atrial Fibrillation

Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF ⬇️

scientific article published on March 7, 2012

Rivaroxaban for stroke prevention in East Asian patients from the ROCKET AF trial

scientific article published on 24 April 2014

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

Rivaroxaban, an oral direct factor Xa inhibitor

scientific article published on 01 June 2008

ST-segment recovery and outcome after primary percutaneous coronary intervention for ST-elevation myocardial infarction: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial

scientific article

Safety and Efficacy of Rivaroxaban in Patients With Cardiac Implantable Electronic Devices: Observations From the ROCKET AF Trial

scientific article published on 14 June 2017

Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

scientific article published in March 2009

Safety of ticagrelor in patients with baseline conduction abnormalities: A PLATO (Study of Platelet Inhibition and Patient Outcomes) analysis

scientific article published on 07 May 2018

Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non-ST-Segment Elevation Acute Coronary Syndrome Patients: Insights From Clinical Trials Over 17 Years

scientific article published on 7 July 2015

Sharing Data from Cardiovascular Clinical Trials--A Proposal

scientific article

Short- and long-term mortality following bleeding events in patients undergoing percutaneous coronary intervention: insights from four validated bleeding scales in the CHAMPION trials

scientific article

Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT-AF Registry

scientific article published on 31 December 2015

Smoking status and antithrombin therapy in patients with non-ST-segment elevation acute coronary syndrome.

scientific article published on 3 April 2008

Statin use and sex-specific stroke outcomes in patients with vascular disease

scientific article (publication date: June 2006)

Stent Thrombosis With Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes

article

Strategic lessons from the clinical event classification process for the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial

scientific article published on 08 January 2011

Stroke Outcomes With Vorapaxar Versus Placebo in Patients With Acute Coronary Syndromes: Insights From the TRACER Trial

scientific article published on 01 December 2018

Stroke Risk and Treatment in Patients with Atrial Fibrillation and Low CHADS-VASc Scores: Findings From the ORBIT-AF I and II Registries

article published in 2018

Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome

scientific article published on April 2016

Systematic adjudication of myocardial infarction end-points in an international clinical trial

scientific article

Temporal changes in biomarkers and their relationships to reperfusion and to clinical outcomes among patients with ST segment elevation myocardial infarction

scientific article published on 20 June 2016

The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) Study Rationale, Design, and Baseline Characteristics

scientific article published on 13 December 2017

The Effects of Cinacalcet in Older and Younger Patients on Hemodialysis: The Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial

scientific article published on 20 February 2015

The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation

scientific article

The Project Baseline Health Study: a step towards a broader mission to map human health

scientific article published on 05 June 2020

The Systemic Inflammatory Response Syndrome in Patients With ST-Segment Elevation Myocardial Infarction*

article

The anticoagulant therapy with bivalirudin to assist in the performance of percutaneous coronary intervention in patients with heparin-induced thrombocytopenia (ATBAT) study: main results

scientific article published on November 1, 2003

The clinical course of treated hyperparathyroidism among patients receiving hemodialysis and the effect of cinacalcet: the EVOLVE trial

scientific article published on 9 October 2013

The effect of cangrelor and access site on ischaemic and bleeding events: insights from CHAMPION PHOENIX

scientific article published on 23 September 2015

The evaluation and management of dyslipidemia and impaired glucose metabolism during acute coronary syndromes

scientific article published on July 2004

The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations

scientific article published on 10 March 2015

The impact of postrandomization crossover of therapy in acute coronary syndromes care

scientific article published on 08 February 2011

Thrombin-receptor antagonist vorapaxar in acute coronary syndromes

scientific article

Ticagrelor Compared With Clopidogrel in Patients With Prior Lower Extremity Revascularization for Peripheral Artery Disease

scientific article

Ticagrelor Versus Clopidogrel in Elderly Patients With Acute Coronary Syndromes

scientific article published on 01 September 2012

Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery

article

Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial

scientific article published on 27 June 2011

Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial

scientific article published on 19 February 2014

Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

scientific article

Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial

scientific article published on 19 November 2007

Trade-off of myocardial infarction vs. bleeding types on mortality after acute coronary syndrome: lessons from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) randomized trial

scientific article published in March 2017

Treatment Consistency Across Levels of Baseline Renal Function With Rivaroxaban or Warfarin: A ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atr

scientific article

Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial

scientific article published on 03 April 2007

Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines: Findings From ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation).

scientific article published in November 2017

Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials

scientific article published on 8 March 2016

Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years

scientific article published on 17 February 2012

Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease

scientific article

Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients

scientific article

Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction

scientific article (publication date: 27 June 2002)

Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry

scientific article published on 16 July 2013

Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

scientific article

Use and outcomes of antiarrhythmic therapy in patients with atrial fibrillation receiving oral anticoagulation: results from the ROCKET AF trial

scientific article

Use of concomitant aspirin in patients with atrial fibrillation: Findings from the ROCKET AF trial

scientific article published on 22 June 2016

Use of evidence-based cardiac prevention therapy among outpatients with atrial fibrillation

scientific article

Use of thienopyridine prior to presentation with non-ST-segment elevation acute coronary syndrome and association with safety and efficacy of vorapaxar: insights from the TRACER trial

scientific article

Use of troponin assay 99th percentile as the decision level for myocardial infarction diagnosis

scientific article published on 16 June 2017

Usefulness and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention (from the TRACER Trial).

scientific article published on 18 June 2014

Validation of BARC Bleeding Criteria in Patients With Acute Coronary Syndromes: The TRACER Trial

scientific article

Variation in Patient Profiles and Outcomes in US and Non-US Subgroups of the Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION) PHOENIX Trial

scientific article published on June 2016

Vorapaxar in acute coronary syndrome patients undergoing coronary artery bypass graft surgery: subgroup analysis from the TRACER trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome).

scientific article published on 21 November 2013

Vorapaxar in patients with peripheral artery disease and acute coronary syndrome: insights from Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER).

scientific article published on 4 July 2014

Vorapaxar with or without clopidogrel after non-ST-segment elevation acute coronary syndromes: results from the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome trial

scientific article published on 16 September 2014

Vorapaxar, a platelet thrombin-receptor antagonist, in medically managed patients with non-ST-segment elevation acute coronary syndrome: results from the TRACER trial

scientific article published on 13 March 2014

Vorapaxar: emerging evidence and clinical questions in a new era of PAR-1 inhibition

scientific article

Warfarin use and outcomes in patients with atrial fibrillation complicating acute coronary syndromes

scientific article published in February 2010

“Off-Hours” Versus “On-Hours” Presentation in ST-Segment Elevation Myocardial Infarction

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