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List of works by Malcolm Kohler

Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD

scientific article

Actigraphy of Wrist and Ankle for Measuring Sleep Duration in Altitude Travelers

scientific article

Acute exacerbated COPD: room for improvement in key elements of care

scientific article published on 10 October 2017

Adenocarcinoma of the gastrointestinal tract in lung transplanted patients with cystic fibrosis: case series and review of the literature

scientific article published on 31 July 2015

An official American Thoracic Society statement: continuous positive airway pressure adherence tracking systems. The optimal monitoring strategies and outcome measures in adults

scientific article published on September 2013

Analysis of hypoxia-induced noncoding RNAs reveals metastasis-associated lung adenocarcinoma transcript 1 as an important regulator of vascular smooth muscle cell proliferation

scientific article published on January 2017

Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity

scientific article published on 12 January 2017

Analysis of the exhalome: a diagnostic tool of the future

scientific article published on September 2013

Annual progression of endothelial dysfunction in patients with COPD.

scientific article published on 18 September 2017

Apnoea-associated intrathoracic pressure swings create a dynamic arrhythmogenic atrial substrate during sleep: author's reply

scientific article published on 14 October 2015

Are nocturnal breathing, sleep, and cognitive performance impaired at moderate altitude (1,630-2,590 m)?

scientific article published on December 2013

Ascent to moderate altitude impairs overnight memory improvements

scientific article published on 15 November 2014

Association between peripheral muscle strength, exercise performance, and physical activity in daily life in patients with Chronic Obstructive Pulmonary Disease

scientific article

Association of sleep-disordered breathing and disturbed cardiac repolarization in patients with ST-segment elevation myocardial infarction

scientific article published on 23 January 2017

Atherosclerosis and arterial stiffness in obstructive sleep apnea--a cardiovascular magnetic resonance study

scientific article published on 19 April 2012

Augmentation index and central aortic blood pressure in patients with abdominal aortic aneurysms

scientific article published on November 2010

Autoadjusted versus fixed CPAP for obstructive sleep apnoea: a multicentre, randomised equivalence trial

scientific article

Automatic Processing of Nasal Pressure Recordings to Derive Continuous Side-Selective Nasal Airflow and Conductance

Blood Pressure Variability in Obstructive Sleep Apnoea: Data from 4 Randomised Controlled CPAP Withdrawal Trials

scientific article

Breath analysis in real time by mass spectrometry in chronic obstructive pulmonary disease.

scientific article

CPAP holiday: are we there yet?

scientific article published in February 2015

CPAP improves endothelial function in patients with minimally symptomatic OSA: results from a subset study of the MOSAIC trial

scientific article

Cardiac Autonomic Function and Cardiovascular Response to Exercise in Patients with Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on January 25, 2012

Cardiac autonomic dysfunction and health‐related quality of life in patients with chronic obstructive pulmonary disease ⬇️

scientific article published on August 1, 2011

Cerebral oxygenation in patients with OSA: effects of hypoxia at altitude and impact of acetazolamide

scientific article

Cessation of extracorporeal photopheresis in chronic lung allograft dysfunction: effects on clinical outcome in adults

scientific article published on 10 May 2017

Challenges and Perspectives in Obstructive Sleep Apnoea: Report by an working group of the Sleep Disordered Breathing Group of the European Respiratory Society and the European Sleep Research Society

Chronic Obstructive Pulmonary Disease and Cardiac Repolarization: Data from a Randomized Controlled Trial

scientific article

Circulating levels of cell-derived microparticles are reduced by mild hypobaric hypoxia: data from a randomised controlled trial

scientific article

Comments on "Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea" by Sharples et al

scientific article published on 13 August 2015

Comparison of photoplethysmographic and arterial tonometry-derived indices of arterial stiffness

scientific article

Continuous positive airway pressure and liver enzymes in obstructive sleep apnoea: data from a randomized controlled trial

scientific article

Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial

scientific article

Continuous positive airway pressure treatment for obstructive sleep apnoea reduces resting heart rate but does not affect dysrhythmias: a randomised controlled trial

scientific article published on 22 June 2009

Coronary artery calcification, epicardial fat burden, and cardiovascular events in chronic obstructive pulmonary disease

scientific article published on 26 May 2015

CrossTalk proposal: Most of the cardiovascular consequences of OSA are due to increased sympathetic activity

scientific article published in June 2012

Deleterious systemic effects of OSA: how much evidence do we need?

scientific article published on 14 July 2015

Detection and Quantification of Benzothiazoles in Exhaled Breath and Exhaled Breath Condensate by Real-Time Secondary Electrospray Ionization-High-Resolution Mass Spectrometry and Ultra-High Performance Liquid Chromatography

scientific article published on 21 September 2015

Determinants of outcome of solitary fibrous tumors of the pleura: an observational cohort study

scientific article

Diabetes in obstructive sleep apnea

scientific article published in July 2010

Diagnosis and management of haemoptysis

scientific article

Does continuous positive airway pressure therapy improve non-alcoholic fatty liver disease?

scientific article published in February 2016

Does nasal decongestion improve obstructive sleep apnea?

scientific article published on 15 August 2008

Dynamic microvesicle release and clearance within the cardiovascular system: triggers and mechanisms

scientific article published on December 2015

Effect of CPAP Withdrawal on myocardial perfusion in OSA: A randomized controlled trial

scientific article published on 20 April 2016

Effect of CPAP on blood pressure in patients with minimally symptomatic obstructive sleep apnoea: a meta-analysis using individual patient data from four randomised controlled trials

scientific article

Effect of OSA on hypoxic and inflammatory markers during CPAP withdrawal: Further evidence from three randomized control trials

scientific article published on 18 November 2016

Effect of acetazolamide and autoCPAP therapy on breathing disturbances among patients with obstructive sleep apnea syndrome who travel to altitude: a randomized controlled trial

scientific article published on December 2012

Effect of continuous positive airway pressure therapy on circadian patterns of cardiac repolarization in patients with obstructive sleep apnoea: data from a randomized trial

article published in 2018

Effect of simulated obstructive hypopnea and apnea on thoracic aortic wall transmural pressures

scientific article published on 13 June 2013

Effects of acute exposure to moderate altitude on vascular function, metabolism and systemic inflammation

scientific article

Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial

scientific article published in November 2011

Effects of obstructive sleep apnoea on heart rhythm

scientific article published on 20 December 2012

Efficacy of EPAP.

scientific article published on 11 January 2016

Elevated levels of endothelial cell-derived microparticles following short-term withdrawal of continuous positive airway pressure in patients with obstructive sleep apnea: data from a randomized controlled trial

scientific article

Endothelial function and arterial stiffness in minimally symptomatic obstructive sleep apnea

scientific article published on 24 July 2008

Established vascular effects of continuous positive airway pressure therapy in patients with obstructive sleep apnoea-an update

scientific article published on May 2015

Evaluation of Nickel Release from Endobronchial Valves as a Possible Cause of Hypersensitivity Pneumonitis in a Patient Treated with Bronchoscopic Lung Volume Reduction

scientific article published on 15 November 2017

Exhaled breath analysis in obstructive sleep apnea

scientific article published on 6 June 2017

Expanding metabolite coverage of real-time breath analysis by coupling a universal secondary electrospray ionization source and high resolution mass spectrometry--a pilot study on tobacco smokers

scientific article

Fatal liver failure with atorvastatin

scientific article

Feasibility, acceptability and effectiveness of integrated care for COPD patients: a mixed methods evaluation of a pilot community-based programme

scientific article published on 12 December 2017

Finger-in-glove sign in bronchial atresia ⬇️

scientific article published on August 2, 2010

Fire eater's lung: retrospective analysis of 123 cases reported to a National Poison Center

scientific article published on 21 June 2013

Guiding Ketogenic Diet with Breath Acetone Sensors

scientific article published on 28 October 2018

High prevalence of altered cardiac repolarization in patients with COPD.

scientific article

Human breath analysis may support the existence of individual metabolic phenotypes

scientific article

Impact of acetazolamide and CPAP on cortical activity in obstructive sleep apnea patients

scientific article

Impact of comorbidities on physical activity in COPD.

scientific article published on 6 January 2015

Impact of sedation technique on the diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration

scientific article

Impaired postural control in healthy men at moderate altitude (1630 m and 2590 m): data from a randomized trial

scientific article

Indices of hypoxic stress in sleep apnea

scientific article published on November 2009

Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study

scientific article

Is continuous positive airway pressure necessarily an everyday therapy in patients with obstructive sleep apnoea?

scientific article published on 31 January 2014

Is obstructive sleep apnea a risk factor for diabetes?

scientific article published on July 1, 2011

Isolation of Stenotrophomonas maltophilia in asymptomatic lung transplant recipients: effects of treatment on eradication and outcome

scientific article

Kinetics of microRNA Expression in Bronchoalveolar Lavage Fluid Samples

scientific article published on 21 March 2015

Leukoaraiosis on MRI in patients with minimally symptomatic obstructive sleep apnoea

scientific article published on 30 April 2013

Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura

scientific article

Lung Volume Reduction Surgery and Improvement of Endothelial Function and Blood Pressure in Patients with Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial

scientific article published in August 2015

Mass-Spectrometric Detection of Omega-Oxidation Products of Aliphatic Fatty Acids in Exhaled Breath

scientific article published on 31 August 2017

Mechanisms of vascular damage in obstructive sleep apnea

scientific article published on December 2010

Metabolic effects of inhaled salbutamol determined by exhaled breath analysis

scientific article published on 13 September 2017

MicroRNA-223 controls the expression of histone deacetylase 2: a novel axis in COPD.

scientific article

Monitoring diurnal changes in exhaled human breath

scientific article published on 17 December 2012

Monitoring of ventilation during exercise by a portable respiratory inductive plethysmograph

scientific article published in September 2005

Non-invasive, side-selective nasal airflow monitoring

scientific article published in February 2005

OSA and hypertension: do we know all the answers?

scientific article

Obstructive sleep apnea in patients with abdominal aortic aneurysms: highly prevalent and associated with aneurysm expansion

scientific article published on 9 July 2010

Paradoxical decrease in isoprostane and increase in superoxide dismutase following CPAP withdrawal in OSA.

scientific article published in March 2016

Patients with obstructive sleep apnea syndrome benefit from acetazolamide during an altitude sojourn: a randomized, placebo-controlled, double-blind trial

scientific article

Pharmacological approaches to the treatment of obstructive sleep apnoea

article

Physical inactivity and arterial stiffness in COPD.

scientific article

Physiological consequences of CPAP therapy withdrawal in patients with obstructive sleep apnoea-an opportunity for an efficient experimental model

scientific article published in January 2018

Pitfalls of clinical trials on pharmacological treatment for obstructive sleep apnoea: future directions

scientific article published on 02 June 2011

Predicting daily physical activity in patients with chronic obstructive pulmonary disease

scientific article

Predictive factors for exacerbation and re-exacerbation in chronic obstructive pulmonary disease: an extension of the Cox model to analyze data from the Swiss COPD cohort

article

Predictors of long-term compliance with continuous positive airway pressure

scientific article published in September 2010

Predictors of the overlap syndrome and its association with comorbidities in patients with chronic obstructive pulmonary disease

scientific article

Prevalence of acute mountain sickness at 3500 m within and between families: a prospective cohort study

Procoagulant and platelet-derived microvesicle absolute counts determined by flow cytometry correlates with a measurement of their functional capacity

scientific article published on 30 September 2014

Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study

scientific article published on 16 December 2017

Quality of life, physical disability, and respiratory impairment in Duchenne muscular dystrophy

scientific article published on 16 June 2005

Quantifying the speed of fluctuations in systolic blood pressure

scientific article

Quantitative changes in the sleep EEG at moderate altitude (1630 m and 2590 m).

scientific article

Rapid identification of bacteria in blood cultures by mass-spectrometric analysis of volatiles.

scientific article

Real-time exhaled breath analysis in patients with cystic fibrosis and controls.

scientific article published on 20 March 2018

Real-world asthma management with inhaler devices in Switzerland-results of the asthma survey

scientific article published on November 2016

Relationship of aortic stiffness measured by cardiovascular magnetic resonance to arterial stiffness estimates by tonometry

article

Repeated lung volume reduction surgery is successful in selected patients

scientific article published on 29 December 2014

SKUP3 trial: comment

scientific article published on 21 October 2013

SafAIRway: an airway training for pulmonologists performing a flexible bronchoscopy with nonanesthesiologist administered propofol sedation: A prospective evaluation

scientific article

Severe metabolic acidosis in adult patients with Duchenne muscular dystrophy

scientific article published on 30 April 2014

Severe pneumonitis after fire eating

scientific article

Severity of peripheral arterial disease is associated with aortic pressure augmentation and subendocardial viability ratio

scientific article published on 27 August 2012

Side-selective, unobtrusive monitoring of nasal airflow and conductance

scientific article published on 13 July 2006

Simulated Obstructive Sleep Apnea Increases P-Wave Duration and P-Wave Dispersion

scientific article

Sleep respiratory disturbances and arousals at moderate altitude have overlapping electroencephalogram spectral signatures

scientific article

Sympathetic overactivity and cardiovascular disease in patients with chronic obstructive pulmonary disease (COPD).

scientific article published on December 2012

Target-controlled versus fractionated propofol sedation in flexible bronchoscopy: A randomized noninferiority trial

scientific article

The ADO index as a predictor of two-year mortality in general practice-based chronic obstructive pulmonary disease cohorts

scientific article published on 7 August 2014

The effect of continuous positive airway pressure on metabolic variables in patients with obstructive sleep apnoea

scientific article published on February 2014

The effect of continuous positive airway pressure treatment on physical activity in patients with obstructive sleep apnoea: A randomised controlled trial

scientific article published on 7 May 2009

The effect of simulated obstructive apnea and hypopnea on aortic diameter and BP.

scientific article published on 10 March 2011

The effects of Provent on moderate to severe obstructive sleep apnoea during continuous positive airway pressure therapy withdrawal: a randomised controlled trial

scientific article published on 30 May 2013

The effects of continuous positive airway pressure therapy withdrawal on cardiac repolarization: data from a randomized controlled trial

scientific article

The effects of controlled breathing during pulmonary rehabilitation in patients with COPD.

scientific article published on 7 April 2011

The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects

scientific article published on 18 July 2012

The impact of obstructive sleep apnea on aortic disease in Marfan's syndrome

scientific article published on 20 September 2012

The role of the nose in the pathogenesis of obstructive sleep apnea

scientific article published on February 2009

The speed of blood pressure fluctuations in patients with chronic obstructive pulmonary disease.

scientific article published in September 2013

Translating secondary electrospray ionization-high-resolution mass spectrometry to the clinical environment

scientific article published on 7 February 2018

Understanding effects of obstructive sleep apnoea and its treatment on the brain and autonomic regulation needs further research

Vascular dysfunction in chronic obstructive pulmonary disease: current evidence and perspectives ⬇️

scientific article published on February 1, 2012

Why should we care about upper airway inflammation in obstructive sleep apnoea?

scientific article published in October 2016

Withdrawal of Continuous Positive Airway Pressure Therapy for 2 Weeks in Obstructive Sleep Apnoea Patients Results in Increased Circulating Platelet and Leucocyte-Derived Microvesicles

scientific article published on 12 May 2016

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