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List of works by Juan C Almagro

Analysis of antibodies of known structure suggests a lack of correspondence between the residues in contact with the antigen and those modified by somatic hypermutation

article

Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.

scientific article published on 7 December 2005

Antibody Engineering and Therapeutics Conference: The Annual Meeting of the Antibody Society, December 8–12, 2013, Huntington Beach, CA.

scientific article published on 19 September 2013

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA

scientific article published on 3 March 2014

Antibody modeling assessment

scientific article

Antibody-antigen recognition: a canonical structure paradigm

scientific article published on 01 December 1996

Antigen-binding site anatomy and somatic mutations in antibodies that recognize different types of antigens.

scientific article

Biologics and molecular recognition: Mike Brigham-Burke memorial issue.

scientific article published in March 2012

Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition

scientific article published on 01 December 1995

Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain.

scientific article

Crystal structure of human germline antibody 3-23/B3

scientific article published on 24 May 2011

De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins

scientific article

Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model ⬇️

scientific article published on September 1, 1998

Distributions of the use frequencies of amino acids in the hypervariable regions of immunoglobulins

scientific article published on 01 July 1995

Evolution of the structural repertoire of the human V(H) and Vkappa germline genes

scientific article published on 01 December 1997

Frequency analysis of amino acids in the recognition regions of T-cell receptors

scientific article published on 01 January 1996

Human framework adaptation of a mouse anti-human IL-13 antibody

scientific article published on 30 April 2010

Identification of Autoimmune Thrombocytopenic Purpura-Related Epitopes Using Phage-Display Peptide Library ⬇️

scientific article published on March 1, 1998

Identification of differences in the specificity-determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody repertoires.

scientific article published in March 2004

Isolation and characterization of high affinity and highly stable anti-Chikungunya virus antibodies using ALTHEA Gold Libraries™

scientific article published on 30 October 2021

Leveraging SBDD in protein therapeutic development: antibody engineering.

scientific article published on January 2012

Molecular modeling of a T-cell receptor bound to a major histocompatibility complex molecule: implications for T-cell recognition.

scientific article

Natural and man-made V-gene repertoires for antibody discovery.

scientific article

Patterns in the complementary determining regions of immunoglobulins (CDRs).

scientific article published on January 1994

Phage Display Libraries for Antibody Therapeutic Discovery and Development

scientific article published on 23 August 2019

Phage displayed biomolecules as preventive and therapeutic agents.

scientific article

Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy

scientific article

Second antibody modeling assessment (AMA-II).

scientific article published on 26 April 2014

Sequence variability in the fibroin-H intron of domesticated and wild silk moths.

scientific article

Structural differences between the repertoires of mouse and human germline genes and their evolutionary implications

scientific article published on 01 April 1998

Structural diversity in a human antibody germline library

scientific article

Structural insights into humanization of anti-tissue factor antibody 10H10.

scientific article published on 28 December 2017

Structural repertoire in VH pseudogenes of immunoglobulins: comparison with human germline genes and human amino acid sequences

scientific article published on 01 February 1995

Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge

scientific article

Synthetic antibody libraries focused towards peptide ligands.

scientific article

The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response

scientific article published on 01 November 1997

The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing

scientific article

Use of human germline genes in a CDR homology-based approach to antibody humanization.

scientific article published in May 2005

VIR.II: a new interface with the antibody sequences in the Kabat database

scientific article published on 01 July 2001

VIR: a computational tool for analysis of immunoglobulin sequences

scientific article published on 01 January 1995

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