List of works - Susan W. Liebman

"Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+]

scientific article published on 25 October 2006

4OS ribosomal protein from a Saccharomyces cerevisiae antisuppressor mutant exhibiting a unique 2D gel pattern

scientific article published in April 1981

A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance

scientific article published on 18 October 2017

A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast

scientific article

A founder mutation in FLNC is likely a major cause of idiopathic dilated cardiomyopathy in Ashkenazi Jews

scientific article published on 14 August 2020

A mutator affecting the region of the iso-1-cytochrome c gene in yeast

scientific article published on July 1979

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion

scientific article

A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast

scientific article

A translational fidelity mutation in the universally conserved sarcin/ricin domain of 25S yeast ribosomal RNA.

scientific article published on March 1996

A ubiquitin-conjugating enzyme, RAD6, affects the distribution of Ty1 retrotransposon integration positions

scientific article published on March 1993

Allosuppressors that enhance the efficiency of omnipotent suppressors in Saccharomyces cerevisiae

scientific article

Alterations in ribosomal protein RPS28 can diversely affect translational accuracy in Saccharomyces cerevisiae.

scientific article

An accuracy center in the ribosome conserved over 2 billion years

scientific article

An antisuppressor that acts on omnipotent suppressors in yeast

scientific article published on May 1980

An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae

scientific article published on January 2006

Analysis of amyloid aggregates using agarose gel electrophoresis

scientific article

Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

scientific article

Analyzing the birth and propagation of two distinct prions, [PSI+] and [Het-s](y), in yeast

scientific article

Biochemical and genetic methods for characterization of [PIN+] prions in yeast

scientific article published in May 2006

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies

scientific article published on 07 August 2019

Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast

scientific article published in April 2000

Chimeric rRNAs containing the GTPase centers of the developmentally regulated ribosomal rRNAs of Plasmodium falciparum are functionally distinct ⬇️

scientific article published on May 1, 1998

Deletions extending from a single Ty1 element in Saccharomyces cerevisiae

scientific article published on December 1985

Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

scientific article

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

scientific article

Development and validation of a yeast high-throughput screen for inhibitors of Aβ₄₂ oligomerization

scientific article

Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro

scholarly article

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

scientific article published on October 1989

Exploring the basis of [PIN(+)] variant differences in [PSI(+)] induction

scientific article published on 14 June 2013

Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast ⬇️

scientific article published on September 1, 1979

Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae.

scientific article published on December 1996

Genetic and Environmental Factors Affecting the de novo Appearance of the [PSI + ] Prion in Saccharomyces cerevisiae ⬇️

scientific article published on October 1, 1997

Guanidine reduces stop codon read‐through caused by missense mutations in SUP35 or SUP45 ⬇️

scientific article published on May 1, 2003

Heterologous aggregates promote de novo prion appearance via more than one mechanism.

scientific article published on 8 January 2015

Heterologous cross-seeding mimics cross-species prion conversion in a yeast model.

scientific article

Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability

scientific article

Host genes that affect the target-site distribution of the yeast retrotransposon Ty1

scientific article

Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs

scientific article published on 20 January 2016

Inhibition of growth by amber suppressors in yeast ⬇️

scientific article published on February 1, 1976

Integration of an aberrant retrotransposon in Saccharomyces cerevisiae

scientific article published on September 1989

Interaction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae

scientific article

Interactions among prions and prion "strains" in yeast

scientific article

Isolation and characterization of amber suppressors in yeast ⬇️

scientific article published on February 1, 1976

Isolation and properties of an antisuppressor in Saccharomyces cerevisiae specific for an omnipotent suppressor

scientific article

Isolation of omnipotent suppressors in an [eta+] yeast strain

scientific article

Leucine insertion caused by a yeast amber suppressor ⬇️

scientific article published on January 5, 1977

Modulation of Abeta42 low-n oligomerization using a novel yeast reporter system

scientific article

Most, but not all, yeast strains in the deletion library contain the [PIN(+)] prion

scientific article published on March 2010

Mutations in RAD6, a yeast gene encoding a ubiquitin-conjugating enzyme, stimulate retrotransposition

scientific article published on March 1990

Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics

scientific article

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome

scientific article

Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon

scientific article published in August 1976

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins

scientific article published on 8 January 2018

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis

scientific article

Overexpression of theSUP45gene encoding a Sup35p-binding protein inhibits the induction of thede novoappearance of the[PSI+]prion ⬇️

scientific article published on March 3, 1998

P2-350: Yeast cell–based genetic and chemical screens for inhibitors of Aβ42 oligomerization

PSI+ prion variant establishment in yeast ⬇️

scientific article published on September 24, 2012

Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes ⬇️

scientific article published on May 19, 2011

Prion-prion interactions

scientific article published on 06 July 2007

Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity

scientific article

Prions affect the appearance of other prions: the story of [PIN(+)].

scientific article

Prions in yeast

scientific article

Progress toward an ultimate proof of the prion hypothesis

scientific article

Propagation of the [PIN+] prion by fragments of Rnq1 fused to GFP

scientific article published on 06 April 2007

Protein folding: sticky N17 speeds huntingtin pile-up

scientific article

Rearrangements occurring adjacent to a single Ty1 yeast retrotransposon in the presence and absence of full-length Ty1 transcription ⬇️

scientific article published on August 1, 1992

Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration

scientific article published on 21 March 2019

Retrospective. Fred Sherman (1932-2013).

scientific article

Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

scientific article (publication date: 12 May 1995)

Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein

scientific article published on December 1990

Sequestration of essential proteins causes prion associated toxicity in yeast

scientific article published on 11 August 2009

Serine substitutions caused by an ochre suppressor in yeast ⬇️

scientific article published on June 5, 1975

Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast

scientific article published on 30 September 2004

Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates

scientific article published on 5 May 2009

The DEL1 mutator gene in Saccharomyces cerevisiae does not act in trans

scientific article published in January 1985

The Sup35 domains required for maintenance of weak, strong or undifferentiated yeast [PSI+] prions

scientific article published in March 2004

The Ubiquitin-Conjugating Enzyme Rad6 (Ubc2) Is Required for Silencing in Saccharomyces cerevisiae ⬇️

scientific article published on November 1, 1997

The accuracy center of a eukaryotic ribosome

scientific article published on November 1995

The relationship between visible intracellular aggregates that appear after overexpression of Sup35 and the yeast prion-like elements [PSI(+)] and [PIN(+)].

scientific article

The shape of a species barrier

scientific article published in Nature

The story of stolen chaperones: how overexpression of Q/N proteins cures yeast prions

scientific article published on July 2013

The translational function of nucleotide C1054 in the small subunit rRNA is conserved throughout evolution: genetic evidence in yeast

scientific article (publication date: 19 March 1996)

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

scientific article published on 15 February 2009

The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3.

scientific article

The yeast omnipotent suppressor SUP46 encodes a ribosomal protein which is a functional and structural homolog of the Escherichia coli S4 ram protein

scientific article

The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension.

scientific article

Tracking the elusive prion

scientific article

Variant-specific prion interactions: Complicating factors

scientific article published on January 2013

Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins

scientific article

List of works by Susan W. Liebman

"Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+]

4OS ribosomal protein from a Saccharomyces cerevisiae antisuppressor mutant exhibiting a unique 2D gel pattern

A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance

A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast

A founder mutation in FLNC is likely a major cause of idiopathic dilated cardiomyopathy in Ashkenazi Jews

A mutator affecting the region of the iso-1-cytochrome c gene in yeast

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion

A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast

A translational fidelity mutation in the universally conserved sarcin/ricin domain of 25S yeast ribosomal RNA.

A ubiquitin-conjugating enzyme, RAD6, affects the distribution of Ty1 retrotransposon integration positions

Allosuppressors that enhance the efficiency of omnipotent suppressors in Saccharomyces cerevisiae

Alterations in ribosomal protein RPS28 can diversely affect translational accuracy in Saccharomyces cerevisiae.

An accuracy center in the ribosome conserved over 2 billion years

An antisuppressor that acts on omnipotent suppressors in yeast

An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae

Analysis of amyloid aggregates using agarose gel electrophoresis

Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

Analyzing the birth and propagation of two distinct prions, [PSI+] and [Het-s](y), in yeast

Biochemical and genetic methods for characterization of [PIN+] prions in yeast

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies

Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast

Chimeric rRNAs containing the GTPase centers of the developmentally regulated ribosomal rRNAs of Plasmodium falciparum are functionally distinct ⬇️

Deletions extending from a single Ty1 element in Saccharomyces cerevisiae

Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

Development and validation of a yeast high-throughput screen for inhibitors of Aβ₄₂ oligomerization

Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

Exploring the basis of [PIN(+)] variant differences in [PSI(+)] induction

Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast ⬇️

Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae.

Genetic and Environmental Factors Affecting the de novo Appearance of the [PSI + ] Prion in Saccharomyces cerevisiae ⬇️

Guanidine reduces stop codon read‐through caused by missense mutations in SUP35 or SUP45 ⬇️

Heterologous aggregates promote de novo prion appearance via more than one mechanism.

Heterologous cross-seeding mimics cross-species prion conversion in a yeast model.

Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability

Host genes that affect the target-site distribution of the yeast retrotransposon Ty1

Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs

Inhibition of growth by amber suppressors in yeast ⬇️

Integration of an aberrant retrotransposon in Saccharomyces cerevisiae

Interaction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae

Interactions among prions and prion "strains" in yeast

Isolation and characterization of amber suppressors in yeast ⬇️

Isolation and properties of an antisuppressor in Saccharomyces cerevisiae specific for an omnipotent suppressor

Isolation of omnipotent suppressors in an [eta+] yeast strain

Leucine insertion caused by a yeast amber suppressor ⬇️

Modulation of Abeta42 low-n oligomerization using a novel yeast reporter system

Most, but not all, yeast strains in the deletion library contain the [PIN(+)] prion

Mutations in RAD6, a yeast gene encoding a ubiquitin-conjugating enzyme, stimulate retrotransposition

Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome

Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis

Overexpression of theSUP45gene encoding a Sup35p-binding protein inhibits the induction of thede novoappearance of the[PSI+]prion ⬇️

P2-350: Yeast cell–based genetic and chemical screens for inhibitors of Aβ42 oligomerization

PSI+ prion variant establishment in yeast ⬇️

Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes ⬇️

Prion-prion interactions

Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity

Prions affect the appearance of other prions: the story of [PIN(+)].

Prions in yeast

Progress toward an ultimate proof of the prion hypothesis

Propagation of the [PIN+] prion by fragments of Rnq1 fused to GFP

Protein folding: sticky N17 speeds huntingtin pile-up

Rearrangements occurring adjacent to a single Ty1 yeast retrotransposon in the presence and absence of full-length Ty1 transcription ⬇️

Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration

Retrospective. Fred Sherman (1932-2013).

Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein

Sequestration of essential proteins causes prion associated toxicity in yeast

Serine substitutions caused by an ochre suppressor in yeast ⬇️

Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast

Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates

The DEL1 mutator gene in Saccharomyces cerevisiae does not act in trans

The Sup35 domains required for maintenance of weak, strong or undifferentiated yeast [PSI+] prions

The Ubiquitin-Conjugating Enzyme Rad6 (Ubc2) Is Required for Silencing in Saccharomyces cerevisiae ⬇️

The accuracy center of a eukaryotic ribosome

The relationship between visible intracellular aggregates that appear after overexpression of Sup35 and the yeast prion-like elements [PSI(+)] and [PIN(+)].