List of works by Jérôme Nigou

A glycomic approach reveals a new mycobacterial polysaccharide

scientific article

A lipomannan variant with strong TLR-2-dependent pro-inflammatory activity in Saccharothrix aerocolonigenes

scientific article

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

scientific journal article

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria

scientific article

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan

scientific article (publication date: 7 September 2007)

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

scientific article published on 04 August 2009

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

scientific article published on 5 November 2015

Asymmetric Total Synthesis and Structural Revision of DAT₂, an Antigenic Glycolipid from Mycobacterium tuberculosis

scientific article published on 3 April 2024

Bacterial cell wall macroamphiphiles: pathogen-/microbe-associated molecular patterns detected by mammalian innate immune system

scientific article published on 15 June 2012

Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

scientific article published on 2 April 2013

Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis

scientific article published on 11 January 2017

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

scientific journal article

C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

scientific article published on 09 January 2017

Characterization and regulation of inositol monophosphatase activity in Mycobacterium smegmatis

scientific article

Characterization of a truncated lipoarabinomannan from the Actinomycete Turicella otitidis

scientific article

Characterization of mycobacterial protein glycosyltransferase activity using synthetic peptide acceptors in a cell-free assay

scientific article

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

scientific article

Cytidine diphosphate-diacylglycerol synthesis in Mycobacterium smegmatis

scientific article published in October 2002

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

scientific article published on December 2005

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

scientific article published in Scientific Reports

Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+

scientific article

Disruption of Cg-Ppm1, a polyprenyl monophosphomannose synthase, and the generation of lipoglycan-less mutants in Corynebacterium glutamicum

scientific article published on 6 August 2003

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

scientific article published on 05 December 2016

Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2

scientific article

Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea

scientific article

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation

scientific article published on 25 September 2009

Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells

scientific article published on 23 January 2007

Lipid and lipoarabinomannan isolation and characterization

scientific article published on January 2015

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

scientific article published on 21 November 2012

Lipoarabinomannans: from structure to biosynthesis

scientific article

Lipoglycans contribute to innate immune detection of mycobacteria

scientific article

Lipoteichoic acid in Streptomyces hygroscopicus: structural model and immunomodulatory activities

scientific article

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

scientific article published on 24 May 2016

Manipulation of the endocytic pathway and phagocyte functions by Mycobacterium tuberculosis lipoarabinomannan

scientific article

Mannan chain length controls lipoglycans signaling via and binding to TLR2.

scientific article

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

scientific article published on 13 May 2013

Mass spectrometry analysis of intact Francisella bacteria identifies lipid A structure remodeling in response to acidic pH stress

scientific article published on 11 August 2017

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response

scientific article

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan ⬇️

scientific article

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

scientific article published on 2 October 2017

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

scientific article published on 5 January 2011

Purification and biochemical characterization of Mycobacterium tuberculosis SuhB, an inositol monophosphatase involved in inositol biosynthesis

scientific journal article

Rational design of adjuvants targeting the C-type lectin Mincle

scientific article published on 21 February 2017

Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm

scientific article

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages

scientific article published on 9 October 2006

Structural analysis of mycobacterial lipoglycans

scientific article

Structural and functional features of Rhodococcus ruber lipoarabinomannan

scientific article published on June 2003

The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.

scientific article

The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan

scientific article

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

scientific article published on 09 June 2008

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

scientific article published on 14 May 2015

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans

scientific article published in April 2004

Tsukamurella paurometabola lipoglycan, a new lipoarabinomannan variant with pro-inflammatory activity

scientific article

Tuberculosis 2012: biology, pathogenesis and intervention strategies; an update from the city of light

scholarly article by Alexandre Gouzy et al published April 2013 in Research in Microbiology

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