Search filters

List of works by Mamadou Daffé

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone

scientific article

A deficiency in arabinogalactan biosynthesis affects Corynebacterium glutamicum mycolate outer membrane stability

scientific article

A glycosyltransferase involved in biosynthesis of triglycosylated glycopeptidolipids in Mycobacterium smegmatis: impact on surface properties

scientific article

A lipid profile typifies the Beijing strains of Mycobacterium tuberculosis: identification of a mutation responsible for a modification of the structures of phthiocerol dimycocerosates and phenolic glycolipids

scientific journal article

A monoacylglycerol lipase from Mycobacterium smegmatis Involved in bacterial cell interaction

scientific journal article

A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

scholarly article

A single-step sequencing method for the identification of Mycobacterium tuberculosis complex species

scientific article

Anti-mycobacterial activities of some cationic and anionic calix[4]arene derivatives ⬇️

scientific article published on February 2, 2012

Assay Development for Identifying Inhibitors of the Mycobacterial FadD32 Activity ⬇️

scientific article published on January 30, 2013

Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13 ⬇️

scientific article published on July 23, 2012

Biochemical and immunological characterization of a cpn60.1 knockout mutant of Mycobacterium bovis BCG.

scientific article published on 2 December 2010

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

scientific journal article

Cell Wall Peptidolipids of Mycobacterium avium: From Genetic Prediction to Exact Structure of a Nonribosomal Peptide

scientific article published on 30 May 2017

Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism

scientific article

Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex

scientific journal article

Click-chemistry approach to study mycoloylated proteins: Evidence for PorB and PorC porins mycoloylation in Corynebacterium glutamicum

scientific article

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

scientific article

Comparative structural analyses of the alpha-glucan and glycogen from Mycobacterium bovis

scientific article

Cord factor (trehalose 6,6′-dimycolate) forms fully stable and non-permeable lipid bilayers required for a functional outer membrane ⬇️

scientific article published on May 1, 2013

Corynebacterium diphtheriae: identification and characterization of a channel-forming protein in the cell wall

scientific article

Current knowledge on mycolic acids in Corynebacterium glutamicum and their relevance for biotechnological processes

scientific article published on 11 October 2013

Deciphering the genetic bases of the structural diversity of phenolic glycolipids in strains of the Mycobacterium tuberculosis complex

scientific article published on 4 April 2008

Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis

scientific journal article

Design, Synthesis, and Biological Evaluation of New Cinnamic Derivatives as Antituberculosis Agents ⬇️

scientific article published on February 10, 2011

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

scientific article

Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state

scientific article

Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane

scientific article published on 9 October 2017

Elionurus tristis Essential Oil: GC-MS Analysis and Antioxidant and Antituberculosis Activities

Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis

scientific article

Evolution of Mycolic Acid Biosynthesis Genes and Their Regulation during Starvation in Mycobacterium tuberculosis

scientific article

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

scientific article

Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence

scientific article

Functional Characterisation of Three O-methyltransferases Involved in the Biosynthesis of Phenolglycolipids in Mycobacterium tuberculosis ⬇️

scientific article published on March 11, 2013

Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG

scientific article published on 2 March 2007

Functional expression of the PorAH channel from Corynebacterium glutamicum in cell-free expression systems: implications for the role of the naturally occurring mycolic acid modification

scientific article

Further insight into S-adenosylmethionine-dependent methyltransferases: structural characterization of Hma, an enzyme essential for the biosynthesis of oxygenated mycolic acids in Mycobacterium tuberculosis

scientific journal article

Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface

scientific article

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

scientific journal article

Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids

scientific article

Genomics of glycopeptidolipid biosynthesis in Mycobacterium abscessus and M. chelonae

scientific article

Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluations

scientific article

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness

scientific article published on 16 April 2018

I3-Ag85 effect on phthiodiolone dimycocerosate synthesis

scientific article published on 24 October 2017

Identification of a Mycoloyl Transferase Selectively Involved in O-Acylation of Polypeptides in Corynebacteriales ⬇️

scientific article published on July 12, 2013

Identification of a cell-wall channel in the corynemycolic acid-free Gram-positive bacterium Corynebacterium amycolatum.

scientific article

Identification of a stress-induced factor of Corynebacterineae that is involved in the regulation of the outer membrane lipid composition

scientific article published on 02 October 2009

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation

scientific article published on 25 September 2009

Identification of specific posttranslational O-mycoloylations mediating protein targeting to the mycomembrane

scientific article published on 3 April 2017

Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival

scientific article

Identification of the missing trans-acting enoyl reductase required for phthiocerol dimycocerosate and phenolglycolipid biosynthesis in Mycobacterium tuberculosis

scientific journal article

Identification of the polyketide synthase involved in the biosynthesis of the surface-exposed lipooligosaccharides in mycobacteria

scientific article

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria

scientific article published on 22 February 2018

Importance of mycoloyltransferases on the physiology of Corynebacterium glutamicum

scientific article

In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid

scientific article published on January 2004

Increased Vancomycin Susceptibility in Mycobacteria: a New Approach To Identify Synergistic Activity against Multidrug-Resistant Mycobacteria

scientific article published on June 2015

Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis

scientific journal article

Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria

scientific article

Lack of fusion of azurophil granules with phagosomes during phagocytosis of Mycobacterium smegmatis by human neutrophils is not actively controlled by the bacterium

scientific article

Lipid and lipoarabinomannan isolation and characterization

scientific article published on January 2015

LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis

scientific journal article

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model

scientific article

MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II

scientific journal article

Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis

scientific article

Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex

scientific journal article

Multidrug resistance of a porin deletion mutant of Mycobacterium smegmatis

scientific article published on November 2004

Mycobacteria use their surface-exposed glycolipids to infect human macrophages through a receptor-dependent process

scientific article published in December 2004

Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes

scientific article

Mycobacterium tuberculosis Cpn60.2 and DnaK are located on the bacterial surface, where Cpn60.2 facilitates efficient bacterial association with macrophages

scientific journal article

Mycobacterium tuberculosis lineage influences innate immune response and virulence and is associated with distinct cell envelope lipid profiles

scientific article

Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system

scientific article

Mycobacterium tuberculosis proteins involved in mycolic acid synthesis and transport localize dynamically to the old growing pole and septum

scientific article

Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice

scientific article (publication date: 2012)

Mycolic acids: structures, biosynthesis, and beyond

scientific article published on 26 December 2013

NMR localization of the O-mycoloylation on PorH, a channel forming peptide from Corynebacterium glutamicum

scientific article

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system

scientific article published on 27 July 2011

New insights into the biogenesis of the cell envelope of corynebacteria: identification and functional characterization of five new mycoloyltransferase genes in Corynebacterium glutamicum

scientific article published in July 2003

Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus

scientific article

O-mycoloylated proteins from Corynebacterium: an unprecedented post-translational modification in bacteria

scientific article

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

scientific article published on 5 January 2011

Partial redundancy in the synthesis of the D-arabinose incorporated in the cell wall arabinan of Corynebacterineae

scientific article published on August 2008

Priming and activation of mouse macrophages by trehalose 6,6'-dicorynomycolate vesicles from Corynebacterium glutamicum

scientific article published in January 2002

Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery

scientific article

Protein-protein interactions within the Fatty Acid Synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability

scientific journal article

Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer

scientific article published on 8 January 2007

Revisiting the assignment of Rv0241c to fatty acid synthase type II of Mycobacterium tuberculosis

scientific journal article

Revisiting the structure of the anti-neoplastic glucans of Mycobacterium bovis Bacille Calmette-Guerin. Structural analysis of the extracellular and boiling water extract-derived glucans of the vaccine substrains

scientific article

Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frame

scientific journal article

Rv3389C from Mycobacterium tuberculosis, a member of the (R)-specific hydratase/dehydratase family

scientific article published on 6 December 2006

S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases

scientific journal article

Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis

scientific article published on 2 September 2016

SigF controls carotenoid pigment production and affects transformation efficiency and hydrogen peroxide sensitivity in Mycobacterium smegmatis

scientific article published on 19 September 2008

Specificities and functions of the recA and pps1 intein genes of Mycobacterium tuberculosis and application for diagnosis of tuberculosis

scientific journal article

Spontaneous transposition of IS1096 or ISMsm3 leads to glycopeptidolipid overproduction and affects surface properties in Mycobacterium smegmatis

scientific article published on 25 April 2008

Structural elucidation and genomic scrutiny of the C60–C100 mycolic acids of Segniliparus rotundus ⬇️

scientific article published on November 15, 2012

Structure and antigenicity of the major glycolipid from Taenia solium cysticerci ⬇️

scientific article published on January 1, 2002

Synthesis and evaluation of a novel series of pseudo-cinnamic derivatives as antituberculosis agents

scientific article

Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimyc

scientific article published on October 15, 2011

Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring

scientific article published on October 2010

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes

scientific article

The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatis

scientific article published on 23 December 2015

The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis

scientific article published on 12 May 2009

The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth: identification of the carboxylation product and determination of the acyl-CoA carboxylase co

scientific journal article

The biosynthesis of mycolic acids in Mycobacterium tuberculosis relies on multiple specialized elongation complexes interconnected by specific protein-protein interactions

scientific journal article

The cell envelope of tubercle bacilli

scientific article published on 13 March 2015

The cell envelope structure and properties of Mycobacterium smegmatis mc(2)155: is there a clue for the unique transformability of the strain?

scientific article published in June 2005

The cell surface-exposed glycopeptidolipids confer a selective advantage to the smooth variants of Mycobacterium smegmatis in vitro

scientific article

The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.

scientific article

The crucial role of trehalose and structurally related oligosaccharides in the biosynthesis and transfer of mycolic acids in Corynebacterineae

scientific article published on 18 May 2005

The dual function of the Mycobacterium tuberculosis FadD32 required for mycolic acid biosynthesis.

scientific article published in May 2009

The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis

scientific article published in October 2002

The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis

scientific journal article

The polyketide synthase Pks13 catalyzes a novel mechanism of lipid transfer in mycobacteria

scientific article

The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

scientific journal article

Trafficking pathways of mycolic acids: structures, origin, mechanism of formation, and storage form of mycobacteric acids

scientific article

Transport assays and permeability in pathogenic mycobacteria

scientific article published in January 2009

mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis

scientific article

p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis

scientific journal article

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

scientific article published on 27 January 2016

Paulina is supported by:

About Paulina

Help