List of works - Lars Karlsson

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

scientific journal article

Antigen Presenting Cells as Drug Targets

Cathepsin S inhibitors as novel immunomodulators

scientific article

Clinical and preclinical characterization of the histamine H(4) receptor antagonist JNJ-39758979.

scientific article published on 18 February 2014

Cloning, expression, purification, and activity of dog (Canis familiaris) and monkey (Saimiri boliviensis) cathepsin S.

scientific article published in March 2003

Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

scientific article

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: part 1.

scientific article

Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

scientific article published on March 2005

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus

scientific article

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

scientific article published on May 2004

Histamine H4receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands

scientific article

Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor ⬇️

scientific article published on October 17, 2003

Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S.

scientific article published in September 2004

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists

scientific article published on December 2005

Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: optimization of cellular potency

scientific article published on 10 September 2009

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements

scientific article

Pyrazole-based cathepsin S inhibitors with improved cellular potency

scientific article published in 2007

TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders

scientific article published on December 2007

The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors

scientific article published on 3 February 2006

The first potent and selective non-imidazole human histamine H4 receptor antagonists

scientific article published on September 2003

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells

scientific article published in June 2006

Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors

scientific article

List of works by Lars Karlsson

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

Antigen Presenting Cells as Drug Targets

Cathepsin S inhibitors as novel immunomodulators

Clinical and preclinical characterization of the histamine H(4) receptor antagonist JNJ-39758979.

Cloning, expression, purification, and activity of dog (Canis familiaris) and monkey (Saimiri boliviensis) cathepsin S.

Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: part 1.

Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

Histamine H4receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands

Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor ⬇️

Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S.

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists

Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: optimization of cellular potency

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements

Pyrazole-based cathepsin S inhibitors with improved cellular potency

TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders

The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors

The first potent and selective non-imidazole human histamine H4 receptor antagonists

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells

Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors