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List of works by Anirban Maitra

'Diseases Desperate Grown by Desperate Appliance Are Relieved, or Not at all' - Towards Finding a Cure for Pancreatic Cancer, Where Do We Stand Today?

scientific article published on 28 September 2018

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

scientific article

A Broad Survey of Cathepsin K Immunoreactivity in Human Neoplasms ⬇️

scientific article published on February 1, 2013

A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms

scientific article published on 28 June 2018

A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice

scientific article

A New Scalpel for the Treatment of Pancreatic Cancer: Targeting Stromal-Derived STAT3 Signaling

scientific article published on 22 October 2015

A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer ⬇️

scientific article published on 01 August 2020

A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer

scientific article published on 01 April 2019

A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer

scientific article published on 01 November 2018

A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma

scientific article published on 06 August 2018

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy ⬇️

scientific article published on June 1, 2012

A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.

scientific article

A draft map of the human proteome

scientific article (publication date: 29 May 2014)

A microfluidic device for label-free isolation of tumor cell clusters from unprocessed blood samples

scientific article published on 01 July 2019

A new mouse model of pancreatic cancer: PTEN gets its Akt together

scientific article published in September 2005

A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients

scientific article published in December 2017

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma

scientific article

A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination

scientific article published on 06 February 2019

A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists

scientific article

A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

scientific article

A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma

scientific article published on 16 October 2015

A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors ⬇️

scientific article published on March 1, 2011

A proteomic analysis of human bile

scientific article

A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells

scientific article

A subset of pancreatic adenocarcinomas demonstrates coamplification of topoisomerase IIalpha and HER2/neu: use of immunolabeling and multicolor FISH for potential patient screening andtreatment

scientific article published on 01 January 2005

AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health

scientific article published on 01 December 2018

Aberrant Hypermethylation of Tumor Suppressor Genes in Pancreatic Endocrine Neoplasms ⬇️

scientific article published on September 1, 2003

Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma

scientific article

Aberrant expression of maspin in idiopathic inflammatory bowel disease is associated with disease activity and neoplastic transformation

scientific article published on January 2005

Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms ⬇️

scientific article (publication date: September 2003)

Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines

scientific article (publication date: 20 June 2002)

Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy

scientific article published on 27 September 2008

Agents targeting the Hedgehog pathway for pancreatic cancer treatment

scientific article published on December 1, 2010

Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery

scientific article

Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways

scientific article published on 6 October 2017

Altered telomeres in tumors with ATRX and DAXX mutations

scientific article

An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.

scientific article published in December 2004

An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration

scientific article published on May 2014

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

scientific article

An in vivo platform for translational drug development in pancreatic cancer

scientific article published on 01 August 2006

An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome

scientific article published on September 2006

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

scientific article published on September 2008

Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays

scientific article published in March 2004

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

scientific article published on 29 March 2018

Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors

scientific article published on 13 October 2008

Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer

scientific article published on June 2005

Assessment of celecoxib pharmacodynamics in pancreatic cancer

scientific article published on 01 December 2006

Assessment of gefitinib- and CI-1040-mediated changes in epidermal growth factor receptor signaling in HuCCT-1 human cholangiocarcinoma by serial fine needle aspiration

scientific article published on July 2006

Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma

scientific article

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

scientific article

Bile Ducts and Ductules Are Positive for CD56 (N-CAM) in Most Cases of Extrahepatic Biliary Atresia ⬇️

scientific article published on 01 November 2003

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

scientific article

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

scientific article

CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target.

scientific article published on March 2005

CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesions

scientific article published on 01 March 2005

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations

scientific article published on 22 March 2018

Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma.

scientific article

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

scientific article published on 23 July 2019

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

preprint posted on 4 February 2019

Characterization and Comparison of GITR Expression in Solid Tumors

scientific article published on 29 July 2019

Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer

scientific article published on 19 September 2018

Circulating Tumor Cells and Transforming Growth Factor Beta in Resected Pancreatic Adenocarcinoma

scientific article published on 03 June 2019

Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions

scientific article published on 01 February 2006

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

scientific article

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

scientific article

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

scientific article published on 12 July 2013

Clinicopathological correlation of radiologic measurement of post-therapy tumor size and tumor volume for pancreatic ductal adenocarcinoma

scientific article published on 14 November 2020

Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer

scientific article published on 13 March 2020

Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.

scientific article published on 30 April 2015

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

scientific article published on 5 September 2017

Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer

scientific article published on 04 June 2019

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

scientific article published on 11 January 2019

Comprehensive Proteomic Analysis of Human Pancreatic Juice

article

Computed Tomography-Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer

scientific article published on 23 August 2019

Conceptual framework for cutting the pancreatic cancer fuel supply

scientific article published on August 2012

Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications

scientific article

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

scientific article (publication date: July 2005)

Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma

scientific article

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

scientific article

Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma ⬇️

scientific article published on July 15, 2012

Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer

scientific article published in April 2008

Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification

scientific article published on 21 November 2008

Copy-number variants in patients with a strong family history of pancreatic cancer

article

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

scientific article

Correction: Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis

article

Cost-effectiveness of consensus guideline-based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective

scientific article published on 29 July 2020

Current Status and Future Directions for Screening Patients at High Risk for Pancreatic Cancer

scientific article

Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models ⬇️

scientific article published on October 1, 2011

Cyclooxygenase 2 expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia: an immunohistochemical analysis with automated cellular imaging

scientific article published on 01 August 2002

Cystic precursors to invasive pancreatic cancer ⬇️

scientific article published on March 1, 2011

Cytogenetic characterization and gene expression profiling in the rat reflux-induced esophageal tumor model.

scientific article published on March 2007

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

scientific article

DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer

scientific article published on 2 October 2013

DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma

scientific article

Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real World Endoscopic Aspiration Samples

scientific article published on 13 November 2020

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

scientific article

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

scientific article published in October 2002

Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer

scientific article

Diagnostic value of digital droplet polymerase chain reaction and digital multiplexed detection of single nucleotide varients in pancreatic cytology specimens collected by EUS-guided FNA

scientific article published on 12 October 2020

Differences in survival for patients with resectable versus unresectable metastases from pancreatic islet cell cancer

scientific article

Differential membrane proteomics using 18O-labeling to identify biomarkers for cholangiocarcinoma

scientific article published on 8 October 2008

Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression

scientific article

Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

scientific article published on 01 March 2019

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

scientific article published on July 2003

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

scientific article

Disputed Paternity: The Uncertain Ancestry of Pancreatic Ductal Neoplasia ⬇️

scientific article published on December 11, 2012

Dual mitogen-activated protein kinase and epidermal growth factor receptor inhibition in biliary and pancreatic cancer

scientific article published on March 2007

Dynamic changes during the treatment of pancreatic cancer

scientific article published on 13 February 2018

EMT and dissemination precede pancreatic tumor formation

scientific article (publication date: 20 January 2012)

EMT: Matter of Life or Death?

scientific article published on 01 February 2016

ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.

scientific article published on 15 June 2016

Early Detection of Pancreatic Cancer: Opportunities and Challenges

scientific article published on 02 February 2019

Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy ⬇️

scientific article published on 25 May 2020

Early Detection of Sporadic Pancreatic Ductal Adenocarcinoma: Problems, Promise, and Prospects

scientific article published on 17 March 2020

Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas

scientific article

Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma

scientific article

Emerging molecular biology of pancreatic cancer

scientific article published on July 2008

Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model

scientific journal article

Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents

scientific article

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth

scientific article published on May 2014

Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer

scientific article published on 29 April 2009

Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line

scientific article published on 4 November 2008

Establishment and validation of real-time polymerase chain reaction method for CDH1 promoter methylation

scientific article published on August 2002

Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma.

scientific article published in March 2004

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

scientific article

Evolution of cellular morpho-phenotypes in cancer metastasis.

scientific article

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

scientific article

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

scientific article

Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

scientific article published in Nature Communications

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

scientific article published on 20 October 2016

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

scientific article (publication date: April 2003)

Expression and Clinical Significance of Protein Kinase RNA-Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2α in Pancreatic Ductal Adenocarcinoma

scientific article published on 01 March 2019

Expression and prognostic significance of 14-3-3sigma and ERM family protein expression in periampullary neoplasms

scientific article published on 13 May 2005

Expression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma

scientific article published on 01 November 2019

Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract

scientific article published on March 2004

Expression of novel markers of pancreatic ductal adenocarcinoma in pancreatic nonductal neoplasms: additional evidence of different genetic pathways

scientific article published on 01 June 2005

Expression of the caudal-type homeodomain transcription factors CDX 1/2 and outcome in carcinomas of the ampulla of Vater

scientific article published in March 2005

Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma

scientific article published on 17 January 2019

Fatal toxicity of chloroquine or hydroxychloroquine with metformin in mice

scientific article published on 05 April 2020

First-Line Gemcitabine and Nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma

article

Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma

scientific article published on June 2002

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

scientific article

Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts ⬇️

scientific article published on October 1, 2011

Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.

scientific article published in July 2003

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

scientific article

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

scientific article published on March 2014

GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling

scientific article published on 22 August 2018

Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review

scientific article published on December 2007

Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

scientific article

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

scientific article

Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas

scientific article

Gene expression profiling identifies markers of ampullary adenocarcinoma

scientific article

Generation and testing of clinical-grade exosomes for pancreatic cancer.

scientific article

Genetic mutations associated with cigarette smoking in pancreatic cancer

scientific article

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

scientific article

Genetics and biology of pancreatic ductal adenocarcinoma

scientific article

Genetics and pathology of pancreatic cancer

scientific article

Genome-wide aberrations in pancreatic adenocarcinoma.

scientific article

Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis.

scientific article published in July 2007

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

scientific article published on 16 July 2013

Genomic alterations in cultured human embryonic stem cells

scientific article published on 4 September 2005

Genomic analyses identify molecular subtypes of pancreatic cancer

scientific article published on 24 February 2016

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

scientific article

Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer

scientific article

Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.

scientific article published on December 2003

HLA-G upregulation in pre-malignant and malignant lesions of the gastrointestinal tract

scientific article published on 01 January 2005

HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma

scientific article

HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma

scientific article published on 29 August 2008

Hear Pancreatic Cancer Stem Cells ROR

scientific article published on 01 April 2019

Hedgehog signaling is required for effective regeneration of exocrine pancreas

scientific article published on 16 April 2008

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

scientific article published on 12 September 2004

Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer

scientific article published on 20 January 2020

Hepatocellular carcinomas show abnormal expression of fibronectin protein

scientific article published on 01 August 2002

Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics

scientific article

High prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer

scientific article published on 01 October 2018

Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.

scientific article

Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy

scientific article

Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

scientific article published on December 2005

Human Correlates of Provocative Questions in Pancreatic Pathology ⬇️

scientific article published on November 1, 2012

Human embryonic stem cells have a unique epigenetic signature

scientific article

Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas

scientific article published on 16 October 2012

Hypermutation In Pancreatic Cancer

scientific article

Identification and Analysis of Precursors to Invasive Pancreatic Cancer ⬇️

scientific article published on 01 January 2013

Identification and analysis of precursors to invasive pancreatic cancer.

scientific article

Identification and characterization of membralin, a novel tumor-associated gene, in ovarian carcinoma

scientific article

Identification of novel cellular targets in biliary tract cancers using global gene expression technology

scientific article published on July 2003

Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags

scientific article published on 12 November 2004

Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma.

scientific article published on 17 February 2015

Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays

scientific article published on August 2006

Imaging Axl expression in pancreatic and prostate cancer xenografts

scientific article published on 11 December 2013

Imaging pancreatic cancer using bioconjugated InP quantum dots

scientific article

Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection

scientific article published on 02 December 2020

Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy

scientific article

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells

scientific article published on 28 March 2018

Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions

scientific article published on 01 April 2003

Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47

scientific article published on 01 July 2002

Immunotherapy for Pancreatic Cancer: More Than Just a Gut Feeling

scientific article

Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth

scientific article

Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma

scientific article published on 31 May 2016

In vitro models of pancreatic cancer for translational oncology research

scientific article published on April 2009

In vivo and in vitro propagation of intraductal papillary mucinous neoplasms

scientific article

In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities

scientific article

In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video).

scientific article

Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer

scientific article

Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients

scientific article published on December 2009

Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation ⬇️

scientific article published on November 1, 2003

Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater

scientific article published on 25 January 2017

Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling

scientific article

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

scientific article

Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer

scientific article published on 05 August 2013

Intercepting Pancreatic Cancer: Our Dream Team's Resolve to Stop Pancreatic Cancer

scholarly article published in Pancreas

Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer

scientific article

Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk

scientific article published in March 2018

Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk popul

scientific article published on 25 July 2012

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

scientific article published on 16 June 2016

Isolation and mutational assessment of pancreatic cancer extracellular vesicles using a microfluidic platform

scientific article published on 11 March 2020

Johns Hopkins course: 8th annual Current Topics in Gastrointestinal and Liver Pathology

scientific article published in February 2009

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

scientific article published on 01 November 2019

Lead-time trajectory of CA19-9 as an anchor marker for pancreatic cancer early detection

scientific article published on 10 December 2020

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer

scientific article

Liquid biopsies in pancreatic cancer

scientific article published on 26 September 2019

Liver metastases arising from well-differentiated pancreatic endocrine neoplasms demonstrate increased VEGF-C expression

scientific article published on 01 July 2003

Long interspersed element-1 protein expression is a hallmark of many human cancers

scientific article published on 06 March 2014

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

scientific article

Loss of ARID1A promotes epithelial-mesenchymal transition and sensitizes pancreatic tumors to proteotoxic stress

scientific article published on 06 November 2020

Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors

scientific article published on 11 May 2012

Loss of HNF6 expression correlates with human pancreatic cancer progression

scientific article published on 17 March 2014

Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms

scientific article published on 01 July 2003

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas

scientific article published on 21 September 2011

Loss of heterozygosity analysis of cutaneous melanoma and benign melanocytic nevi: laser capture microdissection demonstrates clonal genetic changes in acquired nevocellular nevi

scientific article published on February 2002

Loss of p27 Nuclear Expression in a Prognostically Favorable Subset of Well-Differentiated Pancreatic Endocrine Neoplasms

scientific article published on 01 November 2003

MAGE1 is expressed by a subset of pancreatic endocrine neoplasms and associated lymph node and liver metastases

scientific article published on 01 January 2003

MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts

scientific article published on 9 March 2011

MKK4 status predicts survival after resection of gastric adenocarcinoma

scientific article published on November 2006

Mac-2-binding protein is a diagnostic marker for biliary tract carcinoma

scientific article published on 01 October 2004

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.

scientific article published in February 2013

Melanoma hyperpigmentation is strongly associated with KIT alterations

scientific article published in October 2009

Mesothelin is a specific biomarker of invasive cancer in the Barrett-associated adenocarcinoma progression model: translational implications for diagnosis and therapy

scientific article

Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms

scientific article published in September 2004

MicroRNA miR-155 is a biomarker of early pancreatic neoplasia

scientific article

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.

scientific article

Mitochondrial DNA as a cancer biomarker

scientific article published on May 2005

Mitochondrial DNA mutations in pancreatic cancer

scientific article (publication date: 2006)

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer

scientific article published on 13 December 2006

Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer

scientific article published on 23 July 2019

Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer

scientific article published in December 2007

Molecular Characteristics of Pancreatic Ductal Adenocarcinoma ⬇️

scientific article published on March 27, 2011

Molecular Determinants of Retinoic Acid Sensitivity in Pancreatic Cancer ⬇️

scientific article published on October 18, 2011

Molecular and Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May be Clinically Relevant?

scientific article published on April 2016

Molecular genetics of pancreatic ductal adenocarcinomas and recent implications for translational efforts

scientific article

Molecular genetics of pancreatic intraepithelial neoplasia

scientific article published on 29 May 2007

Molecular pathogenesis of pancreatic cancer

scientific article published on 01 April 2006

Morphogenesis of pancreatic cancer: role of pancreatic intraepithelial neoplasia (PanINs)

scientific article published on 19 February 2008

Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon.

scientific article published on 26 April 2012

Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray

scientific article

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

scientific article published on 19 July 2020

Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.

scientific article published on September 2006

Mutant proteins as cancer-specific biomarkers

scientific article

Neuroprotective and Neurorescue Effects of a Novel Polymeric Nanoparticle Formulation of Curcumin (NanoCurc™) in the Neuronal Cell Culture and Animal Model: Implications for Alzheimer's disease ⬇️

scientific article published on January 1, 2011

New insights into plasticity of pancreatic cancer: cancer to acinar cell reprogramming by the basic helix-loop-helix transcription factor E47.

scientific article published in July 2015

New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.

scientific article

Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis

scientific article published on 01 June 2003

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.

scientific article published on 10 February 2013

Novel markers of pancreatic adenocarcinoma in fine-needle aspiration: mesothelin and prostate stem cell antigen labeling increases accuracy in cytologically borderline cases

scientific article

Obesity, Intrapancreatic Fatty Infiltration, and Pancreatic Cancer

scientific article published on 20 May 2015

Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas.

scientific article published on 5 March 2008

Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment

scientific article published on 11 February 2020

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia

scientific article

Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays

scientific article published on 01 February 2007

Overexpression of ankyrin1 promotes pancreatic cancer cell growth.

scientific article published on 26 April 2016

Overexpression of claudin proteins in esophageal adenocarcinoma and its precursor lesions

scientific article published on 01 March 2006

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

scientific article

Pancreatic Cancer Database: an integrative resource for pancreatic cancer

scientific article published on 19 May 2014

Pancreatic cancer

journal article published in 2002

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Pancreatic cancer in 2017: Rebooting pancreatic cancer knowledge and treatment options

scientific article published on 10 January 2018

Pancreatic cancer.

scientific article

Pancreatic carcinogenesis

scientific article published on April 2008

Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production?

scientific article

Pancreatic intraepithelial neoplasia

scientific article published in April 2004

Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: of mice and men.

scientific article published on March 2009

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

scientific article

Pdx1 expression in pancreatic precursor lesions and neoplasms

scientific article

Performance of mitochondrial DNA mutations detecting early stage cancer

scientific article

Personalized chemotherapy profiling using cancer cell lines from selectable mice

scientific article

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer ⬇️

scientific article published on December 6, 2010

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma

scientific article published on 20 December 2019

Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer ⬇️

scientific article published on January 29, 2013

Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas

scientific article published on 02 May 2020

Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy

scientific article

Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma ⬇️

scientific article published on August 25, 2011

Positive immunohistochemical staining of KIT in solid-pseudopapillary neoplasms of the pancreas is not associated with KIT/PDGFRA mutations

scientific article published on 16 June 2006

Potentially Curable Pancreatic Adenocarcinoma: ASCO Clinical Practice Guideline Update

scientific article published on 10 June 2019

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

Precursor lesions of pancreatic cancer: molecular pathology and clinical implications

scientific article published on 18 April 2007

Precursors to invasive pancreatic cancer

scientific article

Precursors to pancreatic cancer

scientific article

Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience

scientific article published on 24 October 2016

Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic Cancer ⬇️

scientific article published on 01 March 2011

Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer

scientific article

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

scientific article published on 5 January 2012

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

scientific article

Prognostic Significance of New AJCC Tumor Stage in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Therapy

scientific article published on 13 June 2017

Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemotherapy

scientific article

Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer

scientific article

Prognostic significance of maspin in pancreatic ductal adenocarcinoma: tissue microarray analysis of 223 surgically resected cases

scientific article published on 30 March 2007

Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma

scientific article

Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms.

scientific article

Progression of Gene Hypermethylation in Gallstone Disease Leading to Gallbladder Cancer ⬇️

scientific article published on October 1, 2003

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma

scientific article

Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation

scientific article published on March 2016

Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization

scientific article

Quality of life impact of EUS in patients at risk for developing pancreatic cancer

scientific article published on 01 January 2020

Quantitative imaging to evaluate malignant potential of IPMNs

scientific article published on 31 August 2016

Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer

scientific article published on 01 March 2007

Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer

scientific article published on 01 February 2020

Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs).

scientific article

Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers

scientific article published on 02 March 2019

Recent advances in genomic profiling of adenosquamous carcinoma of the pancreas

scientific article published on 17 August 2017

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

scientific article

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

scientific article

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

scientific journal article

Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice.

scientific article published on 27 May 2011

Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

scientific article

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

scientific article

SMURF1 amplification promotes invasiveness in pancreatic cancer

scientific article

Selected topics in the evaluation of pediatric gastrointestinal mucosal biopsies

scientific article published on May 2009

Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer

scientific article published on 01 May 2019

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer

scientific article published on 4 August 2015

Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer

scientific article published in April 2017

Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer

scientific article

Sialofucosylated podocalyxin is a functional E- and L-selectin ligand expressed by metastatic pancreatic cancer cells

scientific article

Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy.

scientific article published on 9 January 2018

Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression

scientific article published on 01 November 2018

Smad4 overexpression in hepatocellular carcinoma is strongly associated with transforming growth factor beta II receptor immunolabeling

scientific article published on 01 September 2002

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors

scientific article published on February 2012

Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer

scientific article published on 27 November 2017

Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration

scientific article

Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum

scientific article

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

scientific article

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

scholarly article

Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma

scientific article

Subtyping Pancreatic Cancer

scientific article published in October 2015

Superior Mesenteric Artery Margin of Posttherapy Pancreaticoduodenectomy and Prognosis in Patients With Pancreatic Ductal Adenocarcinoma

scientific article published on 21 July 2015

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer ⬇️

scientific article published on November 1, 2012

Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer

scientific article published on 21 July 2016

Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making?

scientific article published on 28 August 2018

Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institution

scientific article published in May 2005

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

scientific article published on 27 March 2019

Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.

scientific article

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

scientific article published on 8 February 2017

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.

scientific article published on 20 July 2010

Systemic delivery of curcumin: 21st century solutions for an ancient conundrum

scientific article published on September 2009

Target discovery and validation in pancreatic cancer

scientific article published on January 2007

Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer

scientific article published on 11 January 2008

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas

scientific article

Targeting chemokine pathways in esophageal adenocarcinoma

scientific article

Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein

scientific article

Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma

scientific article published on 01 June 2006

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

scientific article published on November 2002

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.

scientific article

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

scientific article published on 22 April 2009

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

scientific article

The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma ⬇️

scientific article published on May 29, 2012

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

scientific article

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

scientific article published on May 2004

The V599E BRAF mutation is uncommon in biliary tract cancers

scientific article

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer

scientific article published in November 2009

The emerging roles of F-box proteins in pancreatic tumorigenesis

scientific article published on 15 September 2015

The epidermal growth factor receptor HER2 is not a major therapeutic target in Ewing sarcoma

scientific article published on June 2003

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma

scientific article published on 10 July 2017

The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models

scientific article

The hedgehog pathway and pancreatic cancer

scientific article published on 01 November 2009

The microRNAs, MiR-31 and MiR-375, as candidate markers in Barrett's esophageal carcinogenesis

scientific article

The number and ratio of positive lymph nodes affect pancreatic cancer patient survival after neoadjuvant therapy and pancreaticoduodenectomy

scientific article

The role of stromal cancer-associated fibroblasts in pancreatic cancer.

scientific article published on 28 March 2017

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

scientific article

Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin.

scientific article published on 13 June 2017

Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.

scientific article published on 8 July 2011

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

scientific article (publication date: 27 February 2016)

Tumor targeting and imaging in live animals with functionalized semiconductor quantum rods

scientific article

Tumor-initiating cells are rare in many human tumors

scientific article

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer

scientific article (publication date: 29 April 2011)

Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology

scientific article published on 08 October 2009

Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM).

scientific article published in December 2008

Update on pancreatic intraepithelial neoplasia.

scientific article

Upfront molecular profiling of pancreatic cancer patients - An idea whose time has come

scientific article published on 05 February 2020

Utility of bile duct brushings for the early detection of cholangiocarcinoma in patients with primary sclerosing cholangitis

scientific article published on 01 April 2006

Validation of a Proposed Tumor Regression Grading Scheme for Pancreatic Ductal Adenocarcinoma After Neoadjuvant Therapy as a Prognostic Indicator for Survival

scientific article published on 14 September 2016

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

scientific article

Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy ⬇️

scientific article published on 07 February 2012

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

scientific article published on 8 December 2011

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

scientific article

Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis ⬇️

scientific article published on March 31, 2011

Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia

scientific article

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours ⬇️

scientific article (publication date: 23 October 2003)

YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

scientific article published on 01 November 2019

miR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo

scientific article

miRNA Biomarkers in Cyst Fluid Augment the Diagnosis and Management of Pancreatic Cysts ⬇️

scientific article published on June 21, 2012

microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1 ⬇️

scientific article published on June 11, 2013

p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.

scientific article published on 31 March 2016

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas

scientific article published on 16 December 2014

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

scientific article published on 01 February 2019

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis

scientific article published on 20 July 2015

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