Search filters

List of works by Tong Ying Shun

Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome ⬇️

scientific article published on October 4, 2012

Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z

scientific article

Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library

scientific article published in June 2009

Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.

scientific article

Designing, optimizing, and implementing high-throughput siRNA genomic screening with glioma cells for the discovery of survival genes and novel drug targets

scientific article

Development and Validation of a High-Content Screening Assay to Identify Inhibitors of Cytoplasmic Dynein-Mediated Transport of Glucocorticoid Receptor to the Nucleus ⬇️

scientific article published on July 25, 2012

Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors

scientific article

Development and implementation of a miniaturized high-throughput time-resolved fluorescence energy transfer assay to identify small molecule inhibitors of polo-like kinase 1.

scientific article

Development and optimization of high-throughput in vitro protein phosphatase screening assays

scientific article

Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents

scientific article published on August 2008

Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity

scientific article

Functional genomic analysis of glioblastoma multiforme through short interfering RNA screening: a paradigm for therapeutic development

scientific article

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines

scientific article

HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus

scientific article

High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

scientific article published in January 2018

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines

scientific article

Identification of Chemosensitivity Nodes for Vinblastine through Small Interfering RNA High-Throughput Screens ⬇️

scientific article published on August 31, 2011

Identification of survival genes in human glioblastoma cells by small interfering RNA screening

scientific article published on 25 September 2009

Identifying actives from HTS data sets: practical approaches for the selection of an appropriate HTS data-processing method and quality control review

scientific article

Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits

scientific article

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments

scientific article

Paulina is supported by:

About Paulina

Help