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List of works by William C. Knowler

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

scientific article

A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

scientific article published on 5 May 2017

A High-Carbohydrate, High-Fiber, Low-Fat Diet Results in Weight Loss among Adults at High Risk of Type 2 Diabetes

scientific article published on 27 September 2017

A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes

scientific article

A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

scientific article published on 10 September 2007

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians

scientific article published on 6 February 2015

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.

scientific article

A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes

scientific journal article

A genome-wide association study of BMI in American Indians

scientific article published on 23 June 2011

A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).

scientific article

A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping

scientific article published on June 2007

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

scientific article

Activity patterns of obese adults with type 2 diabetes in the look AHEAD study

scientific article

Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations

scientific article

Adiponectin and development of type 2 diabetes in the Pima Indian population

scientific article

Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes

scientific article

Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes

scientific article published on 8 September 2016

Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death

scientific article

Albuminuria within the "normal" range and risk of cardiovascular disease and death in American Indians: the Strong Heart Study

scientific article published on 01 February 2007

Alcohol consumption predicts hypertension but not diabetes.

scientific article

An epidemiologic study of trends in prevalence of rheumatoid factor seropositivity in Pima Indians: evidence of a decline due to both secular and birth-cohort influences

scientific article published on July 2002

An explanation for the increase in heart disease mortality rates in diabetic Pima Indians: effect of renal replacement therapy

scientific article

Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression

scientific article published on 20 October 2015

Antidepressant medicine use and risk of developing diabetes during the diabetes prevention program and diabetes prevention program outcomes study

scientific article

Arsenic exposure and incidence of type 2 diabetes in Southwestern American Indians

scientific article

Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians

scientific article

Assessing accuracy of genotype imputation in American Indians

scientific article

Assessing the Role of 98 Established Loci for BMI in American Indians

scientific article published on 18 March 2019

Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.

scientific article published on 8 November 2016

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians

scientific article published on 15 December 2015

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians

scientific article

Association of Serum Amyloid A with Kidney Outcomes and All-Cause Mortality in American Indians with Type 2 Diabetes

scientific article published on 22 September 2017

Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial

scientific article published on 30 August 2016

Association of variants in the carnosine peptidase 1 gene (CNDP1) with diabetic nephropathy in American Indians

scientific article published on February 19, 2011

Associations between persistent organic pollutants, type 2 diabetes, diabetic nephropathy and mortality.

scientific article published on 24 April 2017

Autoantibodies against PFDN2 are associated with an increased risk of type 2 diabetes: A case-control study.

scientific article

Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes

scientific article

Between-monitor differences in step counts are related to body size: implications for objective physical activity measurement

scientific article (publication date: 27 April 2011)

COVID-19 in People With Diabetes: Urgently Needed Lessons From Early Reports

scientific article published on 14 May 2020

Can New-Onset Diabetes After Kidney Transplant Be Prevented?

scientific article published on May 1, 2013

Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes

scientific article published on June 24, 2013

Change in the distribution of albuminuria according to estimated glomerular filtration rate in Pima Indians with type 2 diabetes

scientific article published on 10 July 2009

Changing Patterns of Type 2 Diabetes Incidence Among Pima Indians

scientific article published on 27 April 2007

Changing course of diabetic nephropathy in the Pima Indians.

scientific article published on 07 October 2008

Childhood obesity, other cardiovascular risk factors, and premature death

scientific article

Childhood predictors of adult acute insulin response and insulin action

scientific article published on 19 February 2009

Childhood predictors of young-onset type 2 diabetes.

scientific article published on 24 August 2007

Coffee consumption and the incidence of type 2 diabetes

scientific article published in July 2003

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children

scientific article

Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure

scientific article

Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program

scientific article published on 3 August 2010

Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program

scientific article

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians

scientific article published on 28 April 2009

Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects

scientific article (publication date: March 2007)

Comparison of serum cystatin C, serum creatinine, measured GFR, and estimated GFR to assess the risk of kidney failure in American Indians with diabetic nephropathy

scientific article published on 21 January 2013

Components of the "metabolic syndrome" and incidence of type 2 diabetes

scientific article published in October 2002

Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program

scientific article published on 26 October 2016

Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials

scientific article published on 8 September 2009

Depression as a predictor of weight regain among successful weight losers in the diabetes prevention program

scientific article published on September 21, 2012

Depression symptoms and antidepressant medicine use in Diabetes Prevention Program participants

scientific article

Depression, diabetes, and glycemic control in Pima Indians

scientific article published in February 2004

Depression, diabetes, and glycemic control in an American Indian community

scientific article published on May 2008

Depressive Symptoms, Antidepressant Medication Use, and Inflammatory Markers in the Diabetes Prevention Program

scientific article published on 10 October 2017

Depressive symptoms, antidepressant medication use, and new onset of diabetes in participants of the diabetes prevention program and the diabetes prevention program outcomes study

scientific article

Describing patterns of weight changes using principal components analysis: results from the Action for Health in Diabetes (Look AHEAD) research group

scientific article published on 22 July 2009

Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study

scientific article

Diabetes and oral disease: implications for health professionals

scientific article published on March 12, 2012

Diabetic kidneys do deserve a lifestyle change

scientific article published on 01 October 2014

Diabetic nephropathy in American Indians, with a special emphasis on the Pima Indians.

scientific article

Differential methylation of genes in individuals exposed to maternal diabetes in utero

scientific article published on 26 January 2017

Do Measures of Body Fat Distribution Provide Information on the Risk of Type 2 Diabetes in Addition to Measures of General Obesity?: Comparison of anthropometric predictors of type 2 diabetes in Pima Indians

article

Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study

scientific article

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians

article

Early Renal Function Decline in Type 2 Diabetes

scientific article published on November 10, 2011

Early excess weight gain of children in the Pima Indian population

scientific article published in February 2002

Early growth in offspring of diabetic mothers

scientific article published in March 2005

Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment

scientific article published on 26 April 2017

Effect of different methods of accounting for antihypertensive treatment when assessing the relationship between diabetes or obesity and systolic blood pressure

scientific article

Effect of intrauterine diabetes exposure on the incidence of end-stage renal disease in young adults with type 2 diabetes

scientific article

Effect of losartan on prevention and progression of early diabetic nephropathy in American Indians with type 2 diabetes.

scientific article published on April 2013

Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes

scientific article published on 01 February 2007

Effect of severe obesity in childhood and adolescence on risk of type 2 diabetes in youth and early adulthood in an American Indian population

scientific article published on 28 December 2017

Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians

scientific article published on 01 July 2006

Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial

scientific article

Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program

scientific article published on September 11, 2012

Effects of metformin and weight loss on serum alanine aminotransferase activity in the diabetes prevention program

scientific article

Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone

scientific article

Electrocardiographic abnormalities predict deaths from cardiovascular disease and ischemic heart disease in Pima Indians with type 2 diabetes.

scientific article

Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program

scientific article published on 10 December 2007

Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes.

scientific article

Endogenous glucose production, insulin sensitivity, and insulin secretion in normal glucose-tolerant Pima Indians with low birth weight

scientific article

Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project

scientific article

Erratum. Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes. Diabetes 2013;62:3224-3231.

scientific article published on 5 January 2018

Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668-1677.

scientific article

Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668-1677

article

Ethnic-difference markers for use in mapping by admixture linkage disequilibrium

scientific article published on 11 February 2002

Evaluation of A2BP1 as an obesity gene

scientific article

Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans

scholarly article by Michael T. Traurig et al published 22 June 2012 in Obesity

Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans

scientific article published on January 2013

Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program

scientific article published on 10 June 2008

Factors affecting the decline in incidence of diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS)

scientific article

Factors associated with diabetes onset during metformin versus placebo therapy in the diabetes prevention program

scientific article published on April 2007

Family and genetic studies of indices of insulin sensitivity and insulin secretion in Pima Indians

article

Follow-up report on the diagnosis of diabetes mellitus

scientific article published on November 2003

Four-Year Analysis of Cardiovascular Disease Risk Factors, Depression Symptoms, and Antidepressant Medicine Use in the Look AHEAD (Action for Health in Diabetes) Clinical Trial of Weight Loss in Diabetes

scientific article published on January 28, 2013

Four-year change in cardiorespiratory fitness and influence on glycemic control in adults with type 2 diabetes in a randomized trial: the Look AHEAD Trial

scientific article published on 6 December 2012

Functional variants in MBL2 are associated with type 2 diabetes and pre-diabetes traits in Pima Indians and the old order Amish

scientific article

Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program

scientific article published on December 16, 2011

Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials

scientific article

Genetic admixture and gallbladder disease in Mexican Americans

scientific article published in July 1998

Genetic ancestry markers and difference in A1c between African-American and White in the Diabetes Prevention Program

article

Genetic risk of progression to type 2 diabetes and response to intensive lifestyle or metformin in prediabetic women with and without a history of gestational diabetes mellitus

scientific article

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

scientific article published on 25 August 2015

Genome-Wide Linkage Analyses to Identify Loci for Diabetic Retinopathy

scientific article published on 01 April 2007

Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.

scientific article

Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of birth weight

scientific article published on 11 April 2002

Genome-wide linkage analysis of serum adiponectin in the Pima Indian population

scientific article published in September 2003

Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group

scientific article

Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND).

scientific article

Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND).

scientific article

Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study

scientific article

Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring

scientific article published in February 2006

Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians

scientific article published on 21 November 2011

Growth Tracking in Severely Obese or Underweight Children

scientific article

H. pylori seroprevalence and risk of diabetes: An ancillary case-control study nested in the diabetes prevention program

scientific article

Habitual physical activity in children: the role of genes and the environment

scientific article published on October 2005

HbA1c and the Prediction of Type 2 Diabetes in Children and Adults

scientific article

Hematocrit and the incidence of type 2 diabetes in the pima indians

scientific article

Heritability of the severity of diabetic retinopathy: the FIND-Eye study

scientific article published on September 2008

Homocysteine and vitamin B12 concentrations and mortality rates in type 2 diabetes

article

Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial

scientific article

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians

scientific article published on 22 February 2018

Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study

scientific journal article

Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes

scientific article published on 7 March 2013

Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation

scientific article

Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation

scientific article

Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes

scientific article

Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial

scientific article

Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial

scientific article published on 8 March 2016

Impact of weight loss on ankle-brachial index and interartery blood pressures

scientific article published on 24 February 2014

Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetes

scientific article

Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian.

scientific article published in June 2003

Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors

scientific article published on 21 October 2019

Interaction between an 11betaHSD1 gene variant and birth era modifies the risk of hypertension in Pima Indians

scientific article published on 27 September 2004

Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study

scientific article published on 05 October 2020

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

scientific article

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study

scientific article published on November 22, 2012

Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD.

scientific article

Lifestyle Interventions Limit Gestational Weight Gain in Women with Overweight or Obesity: LIFE-Moms Prospective Meta-Analysis

scholarly article by Alan M. Peaceman et al published September 2018 in Obesity

Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants

scientific article

Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial

scientific article published on 9 January 2018

Long-term Association of Depression Symptoms and Antidepressant Medication Use With Incident Cardiovascular Events in the Look AHEAD (Action for Health in Diabetes) Clinical Trial of Weight Loss in Type 2 Diabetes

scientific article published on 04 March 2019

Long-term Effect of Losartan on Kidney Disease in American Indians With Type 2 Diabetes: A Follow-up Analysis of a Randomized Clinical Trial

scientific article published on 9 September 2016

Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study

scientific article published on 22 February 2016

Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indians

scientific article

Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes

scientific article published in October 2003

Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults

scientific article published on 06 February 2020

Low plasma adiponectin concentrations do not predict weight gain in humans

scientific article published on October 2002

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts

scientific article published on 09 February 2011

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant

scientific article published on 03 October 2008

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation

scientific article published on 03 July 2013

MYH9 is associated with nondiabetic end-stage renal disease in African Americans

scientific article

Maternal influence, not diabetic intrauterine environment, predicts children's energy intake

scientific article

Measurement characteristics of the ankle-brachial index: results from the Action for Health in Diabetes study

scientific article published on August 2008

Meprin beta metalloprotease gene polymorphisms associated with diabetic nephropathy in the Pima Indians

scientific article published on 28 October 2005

Metabolic Risk Factors and Type 2 Diabetes Incidence in American Indian Children

scientific article published on 25 February 2016

Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program

scientific article published on 03 October 2019

Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study

scientific article

Mexican American ancestry-informative markers: examination of population structure and marker characteristics in European Americans, Mexican Americans, Amerindians and Asians

scientific article published on 20 November 2003

Optimal diet for glycemia and lipids

scientific article published on January 2006

Optimizing a proteomics platform for urine biomarker discovery

scientific article

Parental longevity and diabetes risk in the Diabetes Prevention Program

scientific article

Perinatal characteristics and risk of rheumatoid arthritis

scientific article published on May 17, 2003

Periodontal disease and mortality in type 2 diabetes

scientific article published in January 2005

Physical Function Following a Long-Term Lifestyle Intervention among Middle Aged and Older Adults with Type 2 Diabetes: the Look AHEAD Study

scientific article published on 19 October 2017

Physical activity, obesity, and the incidence of type 2 diabetes in a high-risk population

scientific article published in October 2003

Plasma glucose regulation and mortality in pima Indians

scientific article published on 10 December 2007

Potential epigenetic dysregulation of genes associated with MODY and type 2 diabetes in humans exposed to a diabetic intrauterine environment: an analysis of genome-wide DNA methylation

scientific article published on 21 January 2014

Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy

scientific article

Predictive power of sequential measures of albuminuria for progression to ESRD or death in Pima Indians with type 2 diabetes

scientific article published on 20 March 2008

Predictive value of albuminuria in American Indian youth with or without type 2 diabetes

scientific article

Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes

scientific article published on September 2005

Pretransplant risk score for new-onset diabetes after kidney transplantation

scientific article

Preventing Diabetes in American Indian Communities

scientific article published on July 1, 2013

Preventing diabetes in obese Latino youth with prediabetes: a study protocol for a randomized controlled trial

scientific article

Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program

scientific article

Prevention of type 2 diabetes: comment on "Lifestyle modification and prevention of type 2 diabetes in overweight Japanese with impaired fasting glucose levels".

scientific article published in August 2011

Progression to Type 2 Diabetes Characterized by Moderate Then Rapid Glucose Increases

article

Quantitative trait linkage studies of diabetes-related traits

scientific article published on April 1, 2003

Rationale and design of the Vitamin D and Type 2 Diabetes (D2d) study: a diabetes prevention trial

scientific article

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

scientific article

Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial

scientific article published on 15 March 2007

Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS)

scientific article published on 18 July 2019

Regression from pre-diabetes to normal glucose regulation in the diabetes prevention program

scientific article

Relationship between inpatient hyperglycemia and insulin treatment after kidney transplantation and future new onset diabetes mellitus

scientific article

Reliability of urinary albumin, total protein, and creatinine assays after prolonged storage: the Family Investigation of Nephropathy and Diabetes

scientific article published on 10 October 2007

Replication of the Association of BDNF and MC4R Variants With Dietary Intake in the Diabetes Prevention Program

scientific article published on 20 August 2016

Response to Comment on: Chakkera et al. Can New-Onset Diabetes After Kidney Transplant Be Prevented? Diabetes Care 2013;36:1406-1412.

scientific article published on October 2013

Response to Comment on: Chakkera et al. Pretransplant Risk Score for New-Onset Diabetes After Kidney Transplantation. Diabetes Care 2011;34:2141–2145.

scientific article published on 10 February 2012

Response to comment on knowler et Al. Preventing diabetes in american Indian communities. Diabetes care 2013;36:1820-1822.

scientific article published on February 2014

Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin

scientific article

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

scientific article published on 7 August 2011

Secular trends in treatment and control of type 2 diabetes in an American Indian population: a 30-year longitudinal study

scientific article

Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).

scientific article

Self-Reported Gastrointestinal Symptoms in Type 2 Diabetes Improve With an Intensive Lifestyle Intervention: Results From the Action for Health in Diabetes (Look AHEAD) Clinical Trial

scientific article

Serum lipids and mortality in an American Indian population: A longitudinal study

scientific article published on 3 October 2017

Simple anthropometrics are more correlated with health variables than are estimates of body composition in Yup'ik people

scientific article published on May 10, 2013

Stability of body weight in type 2 diabetes: Response to Chaudhry et al.

scientific article published in August 2006

Stabilization of glucose in blood samples: why it matters

scientific article published on 12 March 2009

Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians

scientific article published on 29 April 2013

Structural Predictors of Loss of Renal Function in American Indians with Type 2 Diabetes

scientific article published on 20 January 2016

Study design of the Maycoba Project: obesity and diabetes in Mexican Pimas

scientific article published on May 2014

Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions

scientific article published on 9 February 2015

TCF7L2 Polymorphism, Weight Loss and Proinsulin∶Insulin Ratio in the Diabetes Prevention Program

scientific article published on July 26, 2011

TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals

scientific article

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

scientific article published on July 2006

The Association of Arsenic Exposure and Metabolism With Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study

scientific article

The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program

scientific article published on June 29, 2012

The Diabetes Prevention Program: recruitment methods and results

scientific article

The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial

scientific article

The Family Investigation of Nephropathy and Diabetes (FIND): design and methods

scientific article

The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

scientific article published on 08 May 2008

The Long-term Effectiveness of a Lifestyle Intervention in Severely Obese Individuals

scientific article published on March 1, 2013

The Look AHEAD study: a missed opportunity--authors' reply

scientific article published on 01 October 2014

The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program

scientific article

The association of plasma fibrinogen concentration with diabetic microvascular complications in young adults with early-onset of type 2 diabetes

scientific article

The diabetes prevention program and its global implications

scientific article published on July 2003

The effect of differing patterns of childhood body mass index gain on adult physiology in American Indians.

scientific article

The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function

scientific article

The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population

scientific article published in January 2003

The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.

scientific article published on 14 February 2003

The prevention of type 2 diabetes

scientific article

The relationship between insulin sensitivity and maximal oxygen uptake is confounded by method of adjustment for body composition.

scientific article published on 22 September 2013

The separate and joint effects of prolonged QT interval and heart rate on mortality

article

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

scientific article published on August 10, 1995

Treatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort

scientific article published on 27 August 2015

Trends in heart disease death rates in diabetic and nondiabetic Pima Indians

scientific article

Tumor necrosis factor receptors 1 and 2 are associated with early glomerular lesions in type 2 diabetes

scientific article published on 23 September 2015

Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program

scientific article

Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program

scientific article

Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus

scientific article

Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion

scientific article

Validation of a pretransplant risk score for new-onset diabetes after kidney transplantation

scientific article published on 05 September 2013

Value of urinary albumin-to-creatinine ratio as a predictor of type 2 diabetes in pre-diabetic individuals

scientific article published on 16 September 2008

Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.

scientific article

Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians

scientific article

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

scientific article

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article (publication date: December 2007)

Variants in the LEPR gene are nominally associated with higher BMI and lower 24-h energy expenditure in Pima Indians

scientific article

Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q

article

Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program

scientific article

Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention

scientific article published on 27 April 2017

Weight maintenance from young adult weight predicts better health outcomes

scientific article

White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes

scientific article published on 18 July 2017

Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.

scientific article published on 05 December 2013

Within-Trial Cost-Effectiveness of a Structured Lifestyle Intervention in Adults With Overweight/Obesity and Type 2 Diabetes: Results From the Action for Health in Diabetes (Look AHEAD) Study

scientific article published on 09 November 2020