List of works - Kyle J Roux

A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton

scientific journal article

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells ⬇️

scientific article published on March 12, 2012

BioID Identification of Lamin-Associated Proteins.

scientific article published on 26 September 2015

BioID as a Tool for Protein-Proximity Labeling in Living Cells

scientific article published on 01 January 2019

BioID: A Method to Generate a History of Protein Associations

scientific article published on 24 May 2019

BioID: A Screen for Protein-Protein Interactions.

scientific article

BioID: a screen for protein-protein interactions.

scientific article published on 5 November 2013

Blurring the boundary: the nuclear envelope extends its reach.

scientific article

Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1

scientific article published in Scientific Reports

Chromosome 17 loss-of-heterozygosity studies in benign and malignant tumors in neurofibromatosis type 1

scientific article published on 01 August 2000

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

scientific article published on 25 April 2020

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell.

scientific article published on 21 April 2015

Diverse cellular functions of barrier-to-autointegration factor and its roles in disease

scientific article published on 17 August 2020

Dynamics of lamin-A processing following precursor accumulation

scientific article

Elastin region deletions in Williams syndrome

scientific article published on 01 January 1999

Exon 10b of the NF1 gene represents a mutational hotspot and harbors a recurrent missense mutation Y489C associated with aberrant splicing.

scientific article

Filling the Void: Proximity-Based Labeling of Proteins in Living Cells.

scientific article published on 22 September 2016

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria ⬇️

scientific article published on September 14, 2010

Functional association of Sun1 with nuclear pore complexes

scientific article

Identification of Redox and Glucose-Dependent Txnip Protein Interactions

scientific article published on 29 June 2016

Identifying Protein-Protein Associations at the Nuclear Envelope with BioID.

scientific article

MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.

scientific article published on 15 March 2018

Making the LINC: SUN and KASH protein interactions

scientific article

Marked by association: techniques for proximity-dependent labeling of proteins in eukaryotic cells.

scientific article published on 19 February 2013

Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex

scientific article published on 08 August 2019

Molecular alterations resulting from frameshift mutations in peripheral myelin protein 22: implications for neuropathy severity.

scientific article published in December 2005

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

scientific article

Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome.

scientific article published on 29 March 2017

Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation.

scientific article published on 21 December 2012

Nuclear envelope defects in muscular dystrophy.

scientific article published on 7 June 2006

Nuclear forces and cell mechanosensing.

scientific article

Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia

scientific journal article

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

scientific article

Repair of nuclear ruptures requires barrier-to-autointegration factor

scientific article published on 30 May 2019

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton ⬇️

scientific article published on June 7, 2011

The LINC complex is essential for hearing

scientific article

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

scientific article published on December 2016

The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts.

scientific article published on 23 April 2015

UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice

scientific article published on 26 September 2018

VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF.

scientific article published on 21 June 2017

List of works by Kyle J Roux

A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells ⬇️

BioID Identification of Lamin-Associated Proteins.

BioID as a Tool for Protein-Proximity Labeling in Living Cells

BioID: A Method to Generate a History of Protein Associations

BioID: A Screen for Protein-Protein Interactions.

BioID: a screen for protein-protein interactions.

Blurring the boundary: the nuclear envelope extends its reach.

Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1

Chromosome 17 loss-of-heterozygosity studies in benign and malignant tumors in neurofibromatosis type 1

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell.

Diverse cellular functions of barrier-to-autointegration factor and its roles in disease

Dynamics of lamin-A processing following precursor accumulation

Elastin region deletions in Williams syndrome

Exon 10b of the NF1 gene represents a mutational hotspot and harbors a recurrent missense mutation Y489C associated with aberrant splicing.

Filling the Void: Proximity-Based Labeling of Proteins in Living Cells.

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria ⬇️

Functional association of Sun1 with nuclear pore complexes

Identification of Redox and Glucose-Dependent Txnip Protein Interactions

Identifying Protein-Protein Associations at the Nuclear Envelope with BioID.

MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.

Making the LINC: SUN and KASH protein interactions

Marked by association: techniques for proximity-dependent labeling of proteins in eukaryotic cells.

Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex

Molecular alterations resulting from frameshift mutations in peripheral myelin protein 22: implications for neuropathy severity.

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome.

Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation.

Nuclear envelope defects in muscular dystrophy.

Nuclear forces and cell mechanosensing.

Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

Repair of nuclear ruptures requires barrier-to-autointegration factor

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton ⬇️

The LINC complex is essential for hearing

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts.

UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice

VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF.