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List of works by Christopher Portier

A Mathematical Model of Production, Distribution, and Metabolism of Melatonin in Mammalian Systems ⬇️

scientific article published on November 1, 1997

A comprehensive analysis of the animal carcinogenicity data for glyphosate from chronic exposure rodent carcinogenicity studies

scientific article published on 12 February 2020

A discrete time model for the analysis of medium-throughput C. elegans growth data

scientific article

A mechanistic model of effects of dioxin on gene expression in the rat liver

scientific article published in May 1993

A mechanistic model of effects of dioxin on thyroid hormones in the rat

scientific article published on 01 January 1996

A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events

scientific article published in March 1998

A multistage model of carcinogenesis incorporating DNA damage and repair

scientific article published in September 1991

A signal-to-noise crossover dose as the point of departure for health risk assessment

scientific article published on 3 August 2011

A simple procedure for estimating pseudo risk ratios from exposure to non-carcinogenic chemical mixtures

scientific article published on 11 February 2015

A stem cell model for carcinogenesis

scientific article published on April 1994

ATSDR in the 21st century

scientific article published on March 1, 2012

Adverse effects in risk assessment: modeling polychlorinated biphenyls and thyroid hormone disruption outcomes in animals and humans

scientific article

AhR-mediated gene expression in the developing mouse telencephalon

scientific article published on 22 May 2009

Application of a mathematical model to describe the effects of chlorpyrifos on Caenorhabditis elegans development

scientific article

Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

scientific article

Association between traffic related air pollution exposure and direct health care costs in Northern California

scientific article published in 2022

Biological networks for predicting chemical hepatocarcinogenicity using gene expression data from treated mice and relevance across human and rat species

scientific article

Birth and death/differentiation rates of papillomas in mouse skin ⬇️

scientific article published on June 1, 1992

Blood lead level association with lower body weight in NHANES 1999-2006.

scientific article published on 4 October 2013

Building a robust 21st century chemical testing program at the U.S. Environmental Protection Agency: recommendations for strengthening scientific engagement

scientific article

Calculating tumor incidence rates in stochastic models of carcinogenesis

scientific article

Carcinoma formation in NMRI mouse skin painting studies is a process suggesting greater than two stages

scientific article published on January 1995

Cell proliferation and chemical carcinogenesis: a symposium overview

scientific article

Cell proliferation and chemical carcinogenesis: symposium overview

scientific article

Characterization of the Dose–Response of CYP1B1, CYP1A1, and CYP1A2 in the Liver of Female Sprague–Dawley Rats Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

scientific article published in February 1999

Characterization of the proneural gene regulatory network during mouse telencephalon development

scientific article

Characterizing Dose‐Response I: Critical Assessment of the Benchmark Dose Concept ⬇️

scientific article published on 01 February 1998

Characterizing Elevated Urban Air Pollutant Spatial Patterns with Mobile Monitoring in Houston, Texas

scientific article published on 29 January 2020

Characterizing uncertainty and variability in physiologically based pharmacokinetic models: state of the science and needs for research and implementation.

scientific article published on 4 May 2007

Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure

scientific article published on 24 April 2009

Comments on the International Symposium on Light, Endocrine Systems and Cancer.

scientific article published in July 2002

Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data

scientific article

Compound cytotoxicity profiling using quantitative high-throughput screening

scientific article

Comprehensive Environmental Public Health ⬇️

scientific article published on May 1, 2011

Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans

scientific article published on 01 January 2019

Concordance of carcinogenic response between rodent species: potency dependence and potential underestimation

scientific article published on March 1, 1992

Development of a biologically-based controlled growth and differentiation model for developmental toxicology

scientific article published in January 2003

Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA).

scientific article published on 03 March 2016

Distinguishing between models of carcinogenesis: the role of clonal expansion

scientific article published in October 1991

Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: histologic, biochemical, and cell proliferation endpoints

scientific article

Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds"

scientific article

Dose-response modeling of high-throughput screening data

scientific article

Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver ⬇️

scientific article (publication date: 15 June 1992)

Elucidating environmental dimensions of neurological disorders and disease: Understanding new tools from federal chemical testing programs

scientific article published on 28 March 2017

Employing a Mechanistic Model for the MAPK Pathway to Examine the Impact of Cellular all or None Behavior on Overall Tissue Response.

scientific article

Endocrine dismodulation and cancer.

scientific article

Environmental Predictors of US County Mortality Patterns on a National Basis

scientific article published on 2 December 2015

Estimating the global public health implications of electricity and coal consumption

scientific article (publication date: June 2011)

Evaluation of biomonitoring data from the CDC National Exposure Report in a risk assessment context: perspectives across chemicals

scientific article

Evaluation of toxic equivalency factors for induction of cytochromes P450 CYP1A1 and CYP1A2 enzyme activity by dioxin-like compounds

scientific article

Expression and function of 5-HT7 receptors in smooth muscle preparations from equine duodenum, ileum, and pelvic flexure

scientific article published on 11 April 2009

Expression and function of 5-hydroxytryptamine 4 receptors in smooth muscle preparations from the duodenum, ileum, and pelvic flexure of horses without gastrointestinal tract disease

scientific article published on December 2010

Eyes closed: simple, intuitive, statistically sound, and efficient methods for estimating parameters of clonal growth cancer models

scientific article published in October 1998

Gene expression networks

scientific article

Gene interaction network analysis suggests differences between high and low doses of acetaminophen

scientific article published on 15 May 2006

Gene interaction network suggests dioxin induces a significant linkage between aryl hydrocarbon receptor and retinoic acid receptor beta

scientific article

Genetic and environmental pathways to complex diseases

scientific article

Global gene expression profiling of a population exposed to a range of benzene levels

scientific article

Health, economy, and environment: sustainable energy choices for a nation

scientific article

Hepatocarcinogenesis in Female Sprague-Dawley Rats following Discontinuous Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin

scientific article published in April 2000

High-Resolution Air Pollution Mapping with Google Street View Cars: Exploiting Big Data

scientific article

High-resolution mapping of traffic related air pollution with Google street view cars and incidence of cardiovascular events within neighborhoods in Oakland, CA.

scientific article

Human Exposure Estimates for Phthalates

article

Human carcinogenic risk evaluation, Part V: The national toxicology program vision for assessing the human carcinogenic hazard of chemicals.

scientific article

Human consumption of methyleugenol and its elimination from serum

scientific article

Immunologic findings in workers formerly exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and its congeners

scientific article

Impact of physiologically based pharmacokinetic modeling on benchmark dose calculations for TCDD-induced biochemical responses

scientific article published in December 2002

In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows

scientific article published on March 2007

Inconclusive findings: now you see them, now you don't!

scientific article published on February 2014

Induction of lung lesions in female rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article

Inhibition of human and pig ureter motility in vitro and in vivo by the K(+) channel openers PKF 217-744b and nicorandil

scientific article

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

scientific article

Ligand/receptor binding for 2,3,7,8-TCDD: implications for risk assessment

scientific article published on 01 January 1993

Mapping Air Pollution with Google Street View Cars: Efficient Approaches with Mobile Monitoring and Land Use Regression

scholarly article by Kyle P Messier et al published 24 October 2018 in Environmental Science & Technology

Modeling the number and size of hepatic focal lesions following exposure to 2,3,7,8-TCDD.

scientific article published in May 1996

MtBE and cancer in animals: statistical issues with poly-3 survival adjustments for lifetime studies

scientific article published on 26 August 2007

Multiple organ carcinogenicity of inhaled chloroprene (2-chloro-1,3-butadiene) in F344/N rats and B6C3F1 mice and comparison of dose-response with 1,3-butadiene in mice

scientific article published on 01 May 1999

Multistage models of carcinogenesis: an approximation for the size and number distribution of late-stage clones

scientific article published in December 1994

NTP-CERHR expert panel report on the reproductive and developmental toxicity of methanol

scientific article published on May 2004

Pesticide testing on human subjects: weighing benefits and risks

scientific article

Pharmacokinetics of sodium nitrite-induced methemoglobinemia in the rat.

scientific article published in June 2002

Physiological modeling of a proposed mechanism of enzyme induction by TCDD.

scientific article published in May 2001

Qualitative and quantitative experimental models to aid in risk assessment for immunotoxicology

scientific article published on December 1, 1992

Quantitative analysis of multiple phenotype enzyme-altered foci in rat hepatocarcinogenesis experiments: the multipath/multistage model

scientific article published on October 1995

Re: Tarazona et al. (2017): Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5.

scientific article published on 15 June 2017

Report of an ISRTP workshop: progress and barriers to incorporating alternative toxicological methods in the U.S.

scientific article published on 28 July 2006

Risk factors for childhood leukaemia. Discussion and summary

scientific article

Signal-To-Noise Crossover Dose: Sand et al. Respond

scientific article published on 2 July 2012

Stochastic simulation of a multistage model of carcinogenesis

scientific article published in May 1996

Temperature, air pollution, and hospitalization for cardiovascular diseases among elderly people in Denver

scientific article

The Exact Formula for Tumor Incidence in the Two-Stage Model

article

The NIEHS and the National Toxicology Program: an integrated scientific vision

scientific article

The TAO-Gen algorithm for identifying gene interaction networks with application to SOS repair in E. coli

scientific article

The Use of Signal-Transduction and Metabolic Pathways to Predict Human Disease Targets from Electric and Magnetic Fields Using in vitro Data in Human Cell Lines

scientific article

The application of a multistage model that incorporates DNA damage and repair to the analysis of initiation/promotion experiments

scientific article published on July 1991

The association between biomarker-based exposure estimates for phthalates and demographic factors in a human reference population

scientific article

The forest for the trees: a systems approach to human health research

scientific article

The next generation of risk assessment multi-year study - highlights of findings, applications to risk assessment, and future directions

journal article published in 2016

The two-stage model of carcinogenesis: overcoming the nonidentifiability dilemma

scientific article published in June 1997

The use of animal tests in risk assessment for immunotoxicology ⬇️

scientific article published on October 1, 1994

Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview

scientific article published on August 2003

Toxicogenomics: the new frontier in risk analysis

scientific article published in June 2002

Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: identification of key issues.

scientific article published on 28 June 2008

Update to 'Re: Tarazona et al. (2017): glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5'.

scientific article published on 11 December 2017

Upstream adverse effects in risk assessment: a model of polychlorinated biphenyls, thyroid hormone disruption and neurological outcomes in humans

scientific article published on 7 July 2012

Using cell replication data in mathematical modeling in carcinogenesis

scientific article

Variation in the hepatic gene expression in individual male Fischer rats.

scientific article

What role for biologically based dose-response models in estimating low-dose risk?

scientific article

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