List of works - Donna Davies

"Velcro-type" crackles predict specific radiologic features of fibrotic interstitial lung disease.

scientific article

A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD

scientific article published on 04 June 2018

A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis.

scientific article

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

scientific article

A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells

scientific article

A new look at the pathogenesis of asthma

scientific article

ADAM33 expression in asthmatic airways and human embryonic lungs

scientific article

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

scientific article published on 5 July 2017

Artificial airways for the study of respiratory disease.

scientific article published on December 2011

Asthmatic and normal respiratory epithelial cells respond differently to mechanical apical stress

scientific article published on August 2014

Biocompatibility of poly(2-alkyl-2-oxazoline) brush surfaces for adherent lung cell lines.

scientific article published on 14 May 2015

Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches.

scientific article published on July 2009

Cellular crosstalk between airway epithelial and endothelial cells regulates barrier functions during exposure to double-stranded RNA

scientific article (publication date: March 2017)

Cellular localization of interleukin 13 receptor alpha2 in human primary bronchial epithelial cells and fibroblasts.

scientific article

Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation

scientific article

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development

scientific article

Contribution of eotaxin-1 to eosinophil chemotactic activity of moderate and severe asthmatic sputum.

scientific article published on 4 March 2004

Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts

scientific article published on 07 November 2006

Defective epithelial barrier function in asthma.

scientific article

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma

scientific article

Engineering multi-layered tissue constructs using acoustic levitation

scientific article published on 05 July 2019

Enhancement of neutrophil function by the bronchial epithelium stimulated by epidermal growth factor.

scientific article published on 19 December 2007

Epithelial barrier function and immunity in asthma.

scientific article published on December 2014

Epithelial injury and repair in airways diseases.

scientific article published on December 2013

Establishment of a pulmonary epithelial barrier on biodegradable poly-L-lactic-acid membranes

scientific article published in PLoS ONE

Expression of ErbB receptors and mucins in the airways of long term current smokers.

scientific article published on December 2004

Expression of c-erbB receptors and ligands in human nasal epithelium

scientific article published on 01 December 2000

Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease.

scientific article published on 07 December 2006

IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations

scientific article

IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit

scientific article published on 28 June 2016

Identification of host miRNAs that may limit human rhinovirus replication.

scientific article

Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease

scientific article

In vitro and ex vivo models of human asthma.

scientific article published on 09 January 2013

Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy

scientific article

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

scientific article

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

scientific article

Involvement of the epidermal growth factor receptor in IL-13-mediated corticosteroid-resistant airway inflammation

scientific article published on 24 February 2020

Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry.

scientific article published on 7 August 2009

Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms.

scientific article published on April 2007

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.

scientific article

Low molecular weight components of pollen alter bronchial epithelial barrier functions.

scientific article published on 15 July 2015

Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations

scientific article

Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma.

scientific article

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses

scientific article

Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma ⬇️

scientific article published on September 1, 2003

Medium-term culture of normal human oral mucosa: a novel three-dimensional model to study the effectiveness of drugs administration

scientific article

Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets

scientific article published on January 2012

Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections.

scientific article published on 03 August 2016

Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation.

scientific article published on 15 July 2014

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.

scientific article

Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.

scientific article

On the generation of allergic airway diseases: from GM-CSF to Kyoto.

scientific article

On-chip epithelial barrier function assays using electrical impedance spectroscopy.

scientific article published on 8 April 2010

Osteopontin is expressed and functional in human eosinophils.

scientific article

Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis.

scientific article published on 26 July 2018

Physicochemical characterization of airborne particulate matter at a mainline underground railway station.

scientific article published on 02 April 2013

Preliminary study of the cellular characteristics of primary bronchial fibroblasts in patients with asthma: expression of alpha-smooth muscle actin, fibronectin containing extra type III domain A, and smoothelin

scientific article published on 01 January 2012

Rhinovirus 2A is the key protease responsible for instigating the early block to gene expression in infected cells

scientific article published on 07 January 2020

Role of deficient type III interferon-λ production in asthma exacerbations

article

Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium

scientific article published on 01 November 2001

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life

scientific article

Solution structure of the mEGF/TGFalpha44-50 chimeric growth factor

scientific article

Sputum IL-6 concentrations in severe asthma and its relationship with FEV1

scientific article published on 29 September 2010

Squamous Metaplasia Is Increased in the Bronchial Epithelium of Smokers with Chronic Obstructive Pulmonary Disease

scientific article

Structure-mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model.

scientific article

Targeting the networks that underpin contiguous immunity in asthma and chronic obstructive pulmonary disease.

scientific article published on 30 November 2006

Temporal Monitoring of Differentiated Human Airway Epithelial Cells Using Microfluidics

scientific article published on 5 October 2015

The bronchial epithelium in asthma--much more than a passive barrier.

scientific article published in February 2001

The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma

scientific article published on 01 September 2001

The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial

scientific article

The effects on bronchial epithelial mucociliary cultures of coarse, fine, and ultrafine particulate matter from an underground railway station.

scientific article published on 10 February 2015

The innate antiviral response upregulates IL-13 receptor α2 in bronchial fibroblasts

scientific article published on 12 October 2012

The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma

scientific article published on 01 December 2001

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

scientific article published on 01 February 2003

The role of the epithelium in airway remodeling in asthma.

scientific article published on December 2009

The significance of valine 33 as a ligand-specific epitope of transforming growth factor alpha.

scientific article

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma

scientific article published on 14 April 2008

Thin Film Polycrystalline Silicon Nanowire Biosensors

scientific article published on 26 March 2012

Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis

scientific article

Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response ⬇️

scientific article published on September 6, 2012

Tumor necrosis factor alpha (TNF-α) autoregulates its expression and induces adhesion molecule expression in asthma

scientific article published on 13 March 2011

List of works by Donna Davies

"Velcro-type" crackles predict specific radiologic features of fibrotic interstitial lung disease.

A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD

A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis.

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells

A new look at the pathogenesis of asthma

ADAM33 expression in asthmatic airways and human embryonic lungs

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

Artificial airways for the study of respiratory disease.

Asthmatic and normal respiratory epithelial cells respond differently to mechanical apical stress

Biocompatibility of poly(2-alkyl-2-oxazoline) brush surfaces for adherent lung cell lines.

Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches.

Cellular crosstalk between airway epithelial and endothelial cells regulates barrier functions during exposure to double-stranded RNA

Cellular localization of interleukin 13 receptor alpha2 in human primary bronchial epithelial cells and fibroblasts.

Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development

Contribution of eotaxin-1 to eosinophil chemotactic activity of moderate and severe asthmatic sputum.

Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts

Defective epithelial barrier function in asthma.

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma

Engineering multi-layered tissue constructs using acoustic levitation

Enhancement of neutrophil function by the bronchial epithelium stimulated by epidermal growth factor.

Epithelial barrier function and immunity in asthma.

Epithelial injury and repair in airways diseases.

Establishment of a pulmonary epithelial barrier on biodegradable poly-L-lactic-acid membranes

Expression of ErbB receptors and mucins in the airways of long term current smokers.

Expression of c-erbB receptors and ligands in human nasal epithelium

Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease.

IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations

IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit

Identification of host miRNAs that may limit human rhinovirus replication.

Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease

In vitro and ex vivo models of human asthma.

Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

Involvement of the epidermal growth factor receptor in IL-13-mediated corticosteroid-resistant airway inflammation

Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry.

Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms.

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.

Low molecular weight components of pollen alter bronchial epithelial barrier functions.

Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations

Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma.

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses

Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma ⬇️

Medium-term culture of normal human oral mucosa: a novel three-dimensional model to study the effectiveness of drugs administration

Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets

Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections.

Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation.

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.

Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.

On the generation of allergic airway diseases: from GM-CSF to Kyoto.

On-chip epithelial barrier function assays using electrical impedance spectroscopy.

Osteopontin is expressed and functional in human eosinophils.

Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis.

Physicochemical characterization of airborne particulate matter at a mainline underground railway station.

Preliminary study of the cellular characteristics of primary bronchial fibroblasts in patients with asthma: expression of alpha-smooth muscle actin, fibronectin containing extra type III domain A, and smoothelin

Rhinovirus 2A is the key protease responsible for instigating the early block to gene expression in infected cells

Role of deficient type III interferon-λ production in asthma exacerbations

Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life

Solution structure of the mEGF/TGFalpha44-50 chimeric growth factor

Sputum IL-6 concentrations in severe asthma and its relationship with FEV1

Squamous Metaplasia Is Increased in the Bronchial Epithelium of Smokers with Chronic Obstructive Pulmonary Disease

Structure-mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model.

Targeting the networks that underpin contiguous immunity in asthma and chronic obstructive pulmonary disease.

Temporal Monitoring of Differentiated Human Airway Epithelial Cells Using Microfluidics

The bronchial epithelium in asthma--much more than a passive barrier.

The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma

The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial

The effects on bronchial epithelial mucociliary cultures of coarse, fine, and ultrafine particulate matter from an underground railway station.

The innate antiviral response upregulates IL-13 receptor α2 in bronchial fibroblasts

The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

The role of the epithelium in airway remodeling in asthma.

The significance of valine 33 as a ligand-specific epitope of transforming growth factor alpha.

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma

Thin Film Polycrystalline Silicon Nanowire Biosensors

Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis