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List of works by Andrew Zannettino

4 Adhesion molecules in haemopoiesis ⬇️

scientific article published on September 1, 1997

A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model

scientific article published on 01 April 2011

A method to isolate and purify human bone marrow stromal stem cells.

scientific article

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

scientific article published on 23 June 2016

A novel CD44 antibody identifies an epitope that is aberrantly expressed on acute lymphoblastic leukaemia cells

scientific article published on 01 August 2003

A novel epitope of CD59 expressed by primitive human hematopoietic progenitors ⬇️

scientific article published on December 1, 2001

A role for pericytes as microenvironmental regulators of human skin tissue regeneration

scientific article published on 03 August 2009

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

scientific article published on 12 April 2016

Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer

scientific article published on 16 November 2016

Allogeneic Mesenchymal Precursor Cells Promote Healing in Postero-lateral Annular Lesions and Improve Indices of Lumbar Intervertebral Disc Degeneration in an Ovine Model

scientific article

An Ovine Model of Toxic, Nonischemic Cardiomyopathy—Assessment by Cardiac Magnetic Resonance Imaging

article

An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration

scientific article published on 16 September 2013

Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo.

scientific article published on March 2011

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models

scientific article published on 9 January 2016

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

scientific article published on 10 August 2017

Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathy

scientific article published on 29 June 2010

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

scientific article published on 6 May 2015

Bisphosphonate guidelines for treatment and prevention of myeloma bone disease

scientific article published in August 2017

Bone Marrow Recovery by Morphometry during Induction Chemotherapy for Acute Lymphoblastic Leukemia in Children.

scientific article published on 11 May 2015

Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation

scientific article published on April 2015

CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor

scientific article published in July 2000

Cardiac magnetic resonance, transthoracic and transoesophageal echocardiography: a comparison of in vivo assessment of ventricular function in rats.

scientific article published on 8 July 2013

Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model.

scientific article published in June 2010

Circulating N-cadherin levels are a negative prognostic indicator in patients with multiple myeloma.

scientific article

Circulating levels of TWEAK correlate with bone erosion in multiple myeloma patients

scientific article published on 12 April 2010

Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data.

scientific article

Comparative Assessment of the Osteoconductive Properties of Different Biomaterials In Vivo Seeded with Human or Ovine Mesenchymal Stem/Stromal Cells

scientific article published on 30 August 2010

Concise review: mesenchymal stromal cells: potential for cardiovascular repair.

scientific article published on 03 July 2008

Current and future applications for stem cell therapies in spine surgery.

scientific article published on September 2013

Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma.

scientific article

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment.

scientific article published on 26 October 2017

Decidua Parietalis-Derived Mesenchymal Stromal Cells Reside in a Vascular Niche Within the Choriodecidua

scientific article published on 10 August 2012

Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells.

scientific article published in January 1999

Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis?

scientific article published on 01 June 2008

Dysregulation of bone remodeling by imatinib mesylate.

scientific article

EZH2 and KDM6A act as an epigenetic switch to regulate mesenchymal stem cell lineage specification.

scientific article published in March 2014

EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling.

scientific article published in December 2016

Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration.

scientific article published on 8 November 2013

Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients.

scientific article published on March 2005

Engineering interaction between bone marrow derived endothelial cells and electrospun surfaces for artificial vascular graft applications.

scientific article

Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations

scientific article published on 01 May 2010

EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation.

scientific article published on 14 December 2016

EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation.

scientific article published on 5 November 2010

EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.

scientific article

EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair

article

Evidence for reduced bone formation surface relative to bone resorption surface in female femoral fragility fracture patients.

scientific article published on 22 August 2006

Fabrication and characterisation of an electrospun tubular 3D scaffold platform of poly(vinylidene fluoride-co-hexafluoropropylene) for small-diameter blood vessel application.

scientific article published on 31 October 2014

Genomic profiling of mesenchymal stem cells.

scientific article published on 18 February 2009

HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1.

scientific article published on 30 August 2017

Histone deacetylases (HDAC) in physiological and pathological bone remodelling

scientific article published on 29 November 2016

Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45 /glycophorin-A-bone marrow cells

scientific article published on 01 December 2007

Human osteoblasts are resistant to Apo2L/TRAIL-mediated apoptosis

scientific article published on 01 October 2002

Human trabecular bone-derived osteoblasts support human osteoclast formation in vitro in a defined, serum-free medium.

scientific article

Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.

scientific article published on 29 April 2015

Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.

scientific article

Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells.

scientific article

Identification of Novel EZH2 Targets Regulating Osteogenic Differentiation in Mesenchymal Stem Cells

scientific article published on 10 May 2016

Identification of a common gene expression signature associated with immature clonal mesenchymal cell populations derived from bone marrow and dental tissues.

scientific article published in October 2010

Imatinib as a potential antiresorptive therapy for bone disease.

scientific article published on 31 January 2006

Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs

scientific article published on 09 March 2012

Impact of timing and dose of mesenchymal stromal cell therapy in a preclinical model of acute myocardial infarction.

scientific article published in May 2013

Implanted adult human dental pulp stem cells induce endogenous axon guidance.

scientific article

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

scientific article published on 04 April 2016

Incremental benefits of repeated mesenchymal stromal cell administration compared with solitary intervention after myocardial infarction

scientific article published on 8 October 2013

Inhibition of c-fms by imatinib: expanding the spectrum of treatment.

scientific article published on 28 July 2005

Interaction of platelets with poly(vinylidene fluoride-co-hexafluoropropylene) electrospun surfaces

scientific article published on 18 February 2014

Intramyocardial navigation and mapping for stem cell delivery.

scientific article published on 23 October 2009

Loss of EfnB1 in the osteogenic lineage compromises their capacity to support haematopoietic stem/ progenitor cell maintenance

article

Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development

scientific article published on 10 September 2016

MUC18, a member of the immunoglobulin superfamily, is expressed on bone marrow fibroblasts and a subset of hematological malignancies

scientific article published on 01 March 1998

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

scientific article

Management of systemic AL amyloidosis: recommendations of the Myeloma Foundation of Australia Medical and Scientific Advisory Group.

scientific article

Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium.

scientific article

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy

scientific article published on 18 October 2017

Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche

article

Metabolism of vitamin D3 in human osteoblasts: evidence for autocrine and paracrine activities of 1 alpha,25-dihydroxyvitamin D3.

scientific article published on 2 March 2007

Microarray expression analysis of genes and pathways involved in growth plate cartilage injury responses and bony repair.

scientific article

Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.

scientific article published in May 2003

Molecular cloning of the cell surface antigen identified by the osteoprogenitor-specific monoclonal antibody, HOP-26

scientific article published on 01 May 2003

Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity

article

Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo.

scientific article published in February 2008

Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells.

scientific article

Myeloma-induced alloreactive T cells arising in myeloma-infiltrated bones include double-positive CD8+CD4+ T cells: evidence from myeloma-bearing mouse model.

scientific article published on 9 September 2011

N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer

article

NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells.

scientific article published in October 2010

Near superhydrophobic fibrous scaffold for endothelialization: fabrication, characterization and cellular activities

scientific article published on 04 October 2013

Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration

scientific article

OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib

scientific article published on 04 April 2006

Optimization of the cardiovascular therapeutic properties of mesenchymal stromal/stem cells-taking the next step.

scientific article published on June 2013

Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance

scientific article

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.

scientific article

Osteonecrosis of the jaw complicating bisphosphonate treatment for bone disease in multiple myeloma: an overview with recommendations for prevention and treatment.

scientific article

Osteopontin in the pathophysiology of obesity: Is Opn a fat cell foe?

scientific article published on 01 May 2018

Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor

scientific article published on 01 August 2005

Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone

scientific article published on 01 April 2001

PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesis

scientific article published on 01 September 1999

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.

scientific article

Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: a novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis

scientific article published on 13 December 2017

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.

scientific article published on 8 November 2016

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

scientific article

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

scientific article

Potential applications for using stem cells in spine surgery.

scientific article published on December 2010

Potential roles of growth factor PDGF-BB in the bony repair of injured growth plate.

scientific article published on 5 February 2009

Prospective histomorphometric and DXA evaluation of bone remodeling in imatinib-treated CML patients: evidence for site-specific skeletal effects.

scientific article published on 8 November 2012

Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival

scientific article

RANK Expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone

scientific article published on 01 September 2006

RANKL expression is related to the differentiation state of human osteoblasts.

scientific article

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

scientific article published on 13 March 2020

Reparative Effects of Allogeneic Mesenchymal Precursor Cells Delivered Transendocardially in Experimental Nonischemic Cardiomyopathy

scientific article published on 01 September 2010

Reticulin fibres anchor leukaemic blasts in the marrow of patients with acute lymphoblastic leukaemia

scientific article published on 26 May 2011

SAMSN1 is a tumor suppressor gene in multiple myeloma

scientific article

Specificity and functional effects of antibodies to human stem cell factor.

scientific article

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.

scientific article published on 14 April 2017

Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells.

scientific article

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

scientific article published on 25 July 2018

Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion

scientific article published on 2 April 2012

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

scientific article published on 10 April 2015

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.

scientific article

Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo.

scientific article

The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70.

scientific article published on 27 December 2016

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

scientific article published on 17 February 2017

The effect of the PI3K inhibitor BKM120 on tumour growth and osteolytic bone disease in multiple myeloma.

scientific article published on 7 January 2015

The effect of the dual PI3K and mTOR inhibitor BEZ235 on tumour growth and osteolytic bone disease in multiple myeloma.

scientific article published on 17 September 2014

The efficacy of allogeneic mesenchymal precursor cells for the repair of an ovine tibial segmental defect ⬇️

scientific article published on January 11, 2011

The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma.

scientific article published on 03 June 2011

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints ⬇️

scientific article published on November 12, 2012

The mTORC1 complex in pre-osteoblasts regulates whole-body energy metabolism independently of osteocalcin

scientific article published on 08 February 2021

The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro.

scientific article published on January 2004

The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE).

scientific article published on January 2004

The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption

scientific article published in Scientific Reports

The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells

scientific article published on 15 July 2010

The proliferation and phenotypic expression of human osteoblasts on tantalum metal.

scientific article published in May 2004

The role of the chemokine CXCL12 in osteoclastogenesis.

scientific article published on 21 February 2007

The tyrosine kinase inhibitor dasatinib (SPRYCEL) inhibits chondrocyte activity and proliferation ⬇️

scientific article published on February 4, 2011

Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis.

scientific article

Therapeutic effects of human STRO-3-selected mesenchymal precursor cells and their soluble factors in experimental myocardial ischemia.

scientific article published on October 2011

Therapeutic targeting of N-cadherin is an effective treatment for multiple myeloma.

scientific article published on 20 July 2015

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group.

scientific article published in January 2017

Treatment of patients with multiple myeloma who are eligible for stem cell transplantation: position statement of the Myeloma Foundation of Australia Medical and Scientific Advisory Group.

scientific article published on January 2015

Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: position statement of the myeloma foundation of Australia Medical and Scientific Advisory Group

scientific article

Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

scientific article

Tumor angiogenesis is associated with plasma levels of stromal-derived factor-1alpha in patients with multiple myeloma.

scientific article published on December 2006

Twist-1 Enhances Bone Marrow Mesenchymal Stromal Cell Support of Hematopoiesis by Modulating CXCL12 Expression

scientific article published on 31 December 2015

Twist-1 induces Ezh2 recruitment regulating histone methylation along the Ink4A/Arf locus in mesenchymal stem cells.

scientific article published on 30 January 2012

Tyrosine kinase receptor c-ros-oncogene 1 inhibition alleviates aberrant bone formation of TWIST-1 haploinsufficient calvarial cells from Saethre-Chotzen syndrome patients.

scientific article published on 16 April 2018

Tyrosine kinase receptor c-ros-oncogene 1 mediates TWIST-1 regulation of human mesenchymal stem cell lineage commitment.

scientific article published on 23 September 2016

hTERT transcription is repressed by Cbfa1 in human mesenchymal stem cell populations.

scientific article published on June 2007

mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation

scientific article published on 9 January 2017

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

scientific article published in Scientific Reports

miRNA-376c-3p Mediates TWIST-1 Inhibition of Bone Marrow-Derived Stromal Cell Osteogenesis and Can Reduce Aberrant Bone Formation of TWIST-1 Haploinsufficient Calvarial Cells

scientific article published on 23 October 2018

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