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List of works by Joseph DeSimone

2288. Adherence to Hepatitis B Screening and Treatment Guidelines in Oncology Patients Starting Anti-CD20 Therapy

332. Exploring the Prevalence and Characteristics of Weight Gain and other Metabolic Changes in Patients with HIV Infection Switching to Integrase Inhibitor Containing ART

3D Printed Absorber for Capturing Chemotherapy Drugs before They Spread through the Body

scientific article published on 09 January 2019

866. Increased Diagnosis of Varicella-Zoster Virus Infection of the Central Nervous System With the BioFire FilmArray Meningitis/Encephalitis Panel

979. BMI and ASCVD Risk Score Changes in Virologically Suppressed Patients with HIV Switching from TDF to TAF Containing ART

A Comprehensive Review of Manifestations of Novel Coronaviruses in the Context of Deadly COVID-19 Global Pandemic

scientific article published on 11 May 2020

A combined small-angle neutron and X-ray scattering study of block copolymers micellisation in supercritical carbon dioxide

scientific article published on 16 April 2003

A versatile acid-labile linker for antibody–drug conjugates

Additive manufacturing. Continuous liquid interface production of 3D objects

scientific article

Amorphous linear aliphatic polyesters for the facile preparation of tunable rapidly degrading elastomeric devices and delivery vectors

scientific article published on 01 October 2006

Amphiphilic Co-networks with Moisture-Induced Surface Segregation for High-Performance Nonfouling Coatings ⬇️

scientific article published on August 15, 2011

Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model

scientific article

Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles

scientific article

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

scientific article published on 26 June 2017

Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease

scientific article

Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells

scientific article

Biodistribution and trafficking of hydrogel nanoparticles in adult mosquitoes

scientific article published on 21 May 2015

Biomimetic microlens array with antireflective “moth-eye” surface

article by Doo-Hyun Ko et al published 2011 in Soft Matter

CO(2) Technology Platform: An Important Tool for Environmental Problem Solving A list of abbreviations can be found at the end of the article

scientific article published on 01 February 2001

CO2 Technology Platform: An Important Tool for Environmental Problem Solving

scientific article published in February 2001

CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice

scientific article

Calibration-quality cancer nanotherapeutics

scientific article published on January 2015

Challenging nature’s monopoly on the creation of well-defined nanoparticles

Clinical effectiveness of decitabine in severe sickle cell disease

scientific article published in April 2008

Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease

scientific article

Co-Opting Moore's Law: Vaccines and Medicines made from a Wafer

Co-opting Moore's law: Therapeutics, vaccines and interfacially active particles manufactured via PRINT®.

scientific article published on 13 July 2016

Compliant glass-polymer hybrid single ion-conducting electrolytes for lithium batteries

scientific article

Conductivity of carbonate- and perfluoropolyether-based electrolytes in porous separators

Continuous precipitation polymerization of vinylidene fluoride in supercritical carbon dioxide: A model for understanding the molecular-weight distribution

Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization

scientific article

Controlling release from 3D printed medical devices using CLIP and drug-loaded liquid resins

scientific article published on 27 March 2018

Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues.

scientific article published on 6 June 2009

Crosslinked perfluoropolyether solid electrolytes for lithium ion transport

DNA hypo-methylating agents and sickle cell disease

scientific article published in September 2004

Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription

scientific article

Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway

scientific article

Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer ⬇️

scientific article published on December 21, 2011

Design of asymmetric particles containing a charged interior and a neutral surface charge: comparative study on in vivo circulation of polyelectrolyte microgels

scientific article

Development of a nanoparticle-based influenza vaccine using the PRINT technology.

scientific article

Developmental changes in DNA methylation and covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin gene promoters in Papio anubis

scientific article published on 9 March 2006

Difference between approximate and rigorously measured transference numbers in fluorinated electrolytes

scientific article published on 27 March 2019

Direct fabrication and harvesting of monodisperse, shape-specific nanobiomaterials.

scientific article published in July 2005

Direct patterning of CdSe quantum dots into sub-100 nm structures

scientific article published in March 2010

Dispersion Polymerization of Methyl Methacrylate Stabilized with Poly(1,1-dihydroperfluorooctyl acrylate) in Supercritical Carbon Dioxide

Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted Delivery

scientific article

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

scientific article

Driving convergence with human diversity

scientific article published in May 2014

Drug delivery: Relieving PEGylation

scientific article published on 15 December 2011

Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis

scientific article published on 01 March 2006

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors ⬇️

scientific article published on May 31, 2012

Effect of Aspect Ratio and Deformability on Nanoparticle Extravasation through Nanopores ⬇️

scientific article published on May 29, 2012

Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease

scientific article published on 7 August 2003

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases

scientific article

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons

scientific article published in December 2016

Electron and mass transport in hybrid redox polyether melts contacted with carbon dioxide

scientific article published in August 2002

Engineering nanomedicines using stimuli-responsive biomaterials ⬇️

scientific article published on January 14, 2012

Etchant Solutions for the Removal of Cu(0) in a Supercritical CO2-Based “Dry” Chemical Mechanical Planarization Process for Device Fabrication ⬇️

scientific article published on April 30, 2003

Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle

scientific article published on 3 March 2015

Evaluation of the efficiency of tumor and tissue delivery of carrier-mediated agents (CMA) and small molecule (SM) agents in mice using a novel pharmacokinetic (PK) metric: relative distribution index over time (RDI-OT).

scientific article

Extending antigen release from particulate vaccines results in enhanced antitumor immune response

scientific article published on 13 November 2017

Fabrication of ultramicroelectrodes using a "teflon-like" coating material

scientific article published on 01 May 2005

Flexible biradicals in liquid and supercritical carbon dioxide: the exchange interaction, the chain dynamics, and a comparison with conventional solvents

scientific article published in February 2006

Formation of Perfluoropolyether Coatings by the Rapid Expansion of Supercritical Solutions (RESS) Process. Part 1: Experimental Results

Formation of Poly(1,1,2,2-tetrahydroperfluorodecyl acrylate) Submicron Fibers and Particles from Supercritical Carbon Dioxide Solutions

Formulation of High-Performance Dry Powder Aerosols for Pulmonary Protein Delivery

scientific article published on 23 August 2018

Future of the particle replication in nonwetting templates (PRINT) technology

scientific article

Generality of shear thickening in dense suspensions

scientific article published on 31 January 2010

Generation of a Library of Particles Having Controlled Sizes and Shapes via the Mechanical Elongation of Master Templates

scientific article published on 17 December 2010

Hemoglobinopathies

scientific article published on January 2003

Hierarchical Control of Polymer Composite Nano- and Micro-Structure with Lithography

High Modulus, Low Surface Energy, Photochemically Cured Materials from Liquid Precursors

High-Resolution PFPE-based Molding Techniques for Nanofabrication of High-Pattern Density, Sub-20 nm Features: A Fundamental Materials Approach

article published in 2010

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

scientific article published on January 2015

Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer.

scientific article published on 30 March 2018

Imparting size, shape, and composition control of materials for nanomedicine

scientific article published on 20 September 2006

In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.

scientific article published on 20 October 2011

Incipient microphase separation in short chain perfluoropolyether-block-poly(ethylene oxide) copolymers.

scientific article published on 18 May 2017

Incorporation and controlled release of silyl ether prodrugs from PRINT nanoparticles

scientific article

Influence of the fluid-to-film transition on photophysical properties of MLCT excited states in a polymerizable dimethacrylate fluid.

scientific article published on 14 December 2010

Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy

scientific article published on 29 October 2002

Ion atmosphere relaxation control of electron transfer dynamics in a plasticized carbon dioxide redox polyether melt

scientific article published on 01 January 2003

Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma

scientific article published on 8 February 2016

Joseph DeSimone: What if 3D printing was 100x faster?

TED2015

Layerless fabrication with continuous liquid interface production

scientific article published on 26 September 2016

Liquid perfluoropolyether electrolytes with enhanced ionic conductivity for lithium battery applications

article

Local iontophoretic administration of cytotoxic therapies to solid tumors

scientific article

Long-term survival of dialysis patients after coronary bypass grafting

scientific article published in August 2002

Low modulus biomimetic microgel particles with high loading of hemoglobin

scientific article

Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia

scientific article

Mechanism of ion transport in perfluoropolyether electrolytes with a lithium salt.

scientific article published on 12 July 2017

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location

scientific article published on 13 March 2017

Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer

scientific article

Microfabricated particles for engineered drug therapies: elucidation into the mechanisms of cellular internalization of PRINT particles

scientific article published on July 2008

Micromolding for the fabrication of biological microarrays.

scientific article

Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A.

scientific article published on 19 February 2004

Molded, high surface area polymer electrolyte membranes from cured liquid precursors

scientific article published on 01 October 2006

Molding block copolymer micelles: a framework for molding of discrete objects on surfaces

scientific article published on 08 October 2008

More Effective Nanomedicines through Particle Design ⬇️

scientific article published on June 22, 2011

Multifunctional shape and size specific magneto-polymer composite particles

scientific article

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

scholarly article by Stefan W Metz et al published September 2018 in PLoS Neglected Tropical Diseases

Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy

scientific article published on 27 July 2013

Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells

scientific article published on December 2015

Nanoparticulate immunotherapy for cancer

scientific article published on 29 September 2015

National Trends and Geographic Variation in Bilateral Internal Mammary Artery Use in the United States

scientific article published in November 2017

New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis

scientific article published on 01 August 2020

New phosphate fluorosurfactants for carbon dioxide

scientific article published on 01 March 2002

Nonflammable perfluoropolyether-based electrolytes for lithium batteries

scientific article published on 10 February 2014

Novel materials

scientific article published on October 2016

Novel platforms for vascular carriers with controlled geometry ⬇️

scientific article published on June 30, 2011

Optically transparent, amphiphilic networks based on blends of perfluoropolyethers and poly(ethylene glycol).

scientific article published on 4 October 2008

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses

article

Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons

scientific article published on 17 August 2018

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

scientific article published on 7 September 2017

Organic Polymer Chemistry in the Context of Novel Processes

scientific article

Oxidative dissolution of copper and zinc metal in carbon dioxide with tert-butyl peracetate and a beta-diketone chelating agent

scientific article published in January 2005

PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics ⬇️

scientific article published on September 5, 2012

PKCδ-targeted intervention relieves chronic pain in a murine sickle cell disease model

scientific article published on 27 June 2016

Palette-PrintAR: augmented reality design and simulation for multicolor resin 3D printing

scientific article published on 11 May 2024

Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity

scientific article published on 24 February 2014

Particles for Local Delivery of Proteins Using Intra-Articular Route

scientific article published on 2 February 2016

Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease

scientific article published on 23 February 2017

Phase Behavior and Electrochemical Characterization of Blends of Perfluoropolyether, Poly(ethylene glycol), and a Lithium Salt

article

Photochemically Cross-Linked Perfluoropolyether-Based Elastomers: Synthesis, Physical Characterization, and Biofouling Evaluation

Photocurable Amphiphilic Perfluoropolyether/Poly(ethylene glycol) Networks for Fouling-Release Coatings

article

Photonic Crystal Geometry for Organic Solar Cells

article

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft ⬇️

scientific article published on December 6, 2012

Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents

scientific article published on 01 December 2002

Polymerizations in Supercritical Carbon Dioxide

scientific article published on 01 February 1999

Potent Engineered PLGA Nanoparticles by Virtue of Exceptionally High Chemotherapeutic Loadings ⬇️

scientific article published on January 25, 2011

Practical approaches to green solvents

scientific article published in August 2002

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

scientific article

Preoperative white blood cell count and mortality and morbidity after coronary artery bypass grafting

scientific article published on 01 September 2003

Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity

scientific article

Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung

scientific article published on 24 March 2016

Pulmonary Delivery of Nanoparticle-Bound Toll-Like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer

scientific article published on 28 May 2020

RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model

scientific article published on 27 April 2015

RNA replicon delivery via lipid-complexed PRINT protein particles.

scientific article published on 21 August 2013

Rapid and Persistent Delivery of Antigen by Lymph Node Targeting PRINT Nanoparticle Vaccine Carrier To Promote Humoral Immunity

scientific article

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs

scientific article published on 23 August 2016

Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo

scientific article published on 19 August 2015

Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing ⬇️

scientific article published on April 19, 2012

Reductively labile PRINT particles for the delivery of doxorubicin to HeLa cells

scientific article published on 20 March 2008

Relationship between Conductivity, Ion Diffusion, and Transference Number in Perfluoropolyether Electrolytes

Rendering protein-based particles transiently insoluble for therapeutic applications.

scientific article

Retinoic Acid-Loaded Poly(lactic-co-glycolic acid) Nanoparticle Formulation of ApoB-100-Derived Peptide 210 Attenuates Atherosclerosis

scientific article published on 01 April 2020

Role of Linker Length and Antigen Density in Nanoparticle Peptide Vaccine

scientific article published on 19 March 2019

S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)

scientific article published on 8 October 2010

Scalable, shape-specific, top-down fabrication methods for the synthesis of engineered colloidal particles

scientific article

Self-assembly of phosphate fluorosurfactants in carbon dioxide

scientific article published on 01 February 2004

Shape-specific, monodisperse nano-molding of protein particles

scientific article

Shear thickening and jamming in densely packed suspensions of different particle shapes ⬇️

scientific article published on September 28, 2011

Should Diabetes be a Contraindication to Bilateral Internal Mammary Artery Grafting?

scientific article published on 6 December 2017

Silylated precision particles for controlled release of proteins

scientific article

Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production

scientific article

Solvent-resistant photocurable liquid fluoropolymers for microfluidic device fabrication [corrected].

scientific article published in March 2004

Spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery

scientific article published on 09 June 2018

Standard clinical practice underestimates the role and significance of erythropoietin deficiency in sickle cell disease ⬇️

scientific article published on March 21, 2011

Strategies in the design of nanoparticles for therapeutic applications

scientific article published on 09 July 2010

Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

scientific article

Supramolecular nanomimetics: replication of micelles, viruses, and other naturally occurring nanoscale objects

scientific article published on 01 May 2007

Synthesis and characterization of monodisperse uniformly shaped respirable aerosols

article published in 2013

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation

scientific article

The Carolina Center of Cancer Nanotechnology Excellence: past accomplishments and future perspectives

scientific article published on January 2011

The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice

scientific article published in June 2015

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).

scientific article published on 8 February 2016

The Patterning of Sub-500 nm Inorganic Oxide Structures

scientific article published on 02 June 2008

The effect of particle design on cellular internalization pathways

scholarly article

The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles ⬇️

scientific article published on June 15, 2012

The evolving role of DNA demethylating agents in the treatment of sickle cell disease and thalassemia

scientific article published on 01 October 2004

The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow

scientific article published in January 2007

Top-down particle fabrication: control of size and shape for diagnostic imaging and drug delivery

scientific article published on July 2009

Towards programming immune tolerance through geometric manipulation of phosphatidylserine.

scientific article

Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.

scientific article

Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance

scientific article published on 23 November 2015

Tuning Multiphase Amphiphilic Rods to Direct Self-Assembly ⬇️

scientific article published on October 25, 2011

Ultrathin Cross-Linked Perfluoropolyether Film Coatings from Liquid CO2and Subsequent UV Curing

Use of iontophoresis for the treatment of cancer

scientific article published on 15 June 2018

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

scientific article

Voltammetry and electron-transfer dynamics in a molecular melt of a 1.2 nm metal quantum dot

scientific article published on 01 February 2003

Weak surface anchoring energy of 4-cyano-4'-pentyl-1,1'-biphenyl on perfluoropolyether Langmuir-Blodgett films

scientific article published on 01 June 2007

siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)−dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures ⬇️

scientific article published on October 23, 2010

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