List of works - Jim Selfridge

53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin.

scientific article

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

scientific article published on 24 April 2015

A mutation-led search for novel functional domains in MeCP2

A mutation-led search for novel functional domains in MeCP2.

scientific article published in July 2018

A one-step gene amplification system for use in cultured mammalian cells and transgenic animals

scientific article published on 01 April 2001

A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells

scientific article published on 01 December 1992

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

scientific article published on February 2014

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

scientific article published on 01 August 2018

Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil

scientific article

Comparative analysis of potential broad-spectrum neuronal Cre drivers

scientific article published on 08 July 2022

Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene.

scientific article

CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

scientific article published on April 2010

Domains of methylated CAC and CG target MeCP2 to tune transcription in the brain

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

scientific journal article

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

scientific article

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

scientific article published in October 2016

Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: inactivation of the mouse ERCC-1 gene

scientific article published on July 1, 1992

Kaiso-deficient mice show resistance to intestinal cancer

scientific article

Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice

scientific article

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.

scientific article

Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease

scientific article published on 01 April 2010

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.

scientific article published on 11 October 2017

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

scientific journal article

Stability of HPRT marker gene expression at different gene-targeted loci: observing and overcoming a position effect.

scientific article

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

scientific article published on 8 December 2015

The role of MeCP2 in the brain.

scientific article published on 29 June 2011

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

article

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

scientific article

List of works by Jim Selfridge

53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin.

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

A mutation-led search for novel functional domains in MeCP2

A mutation-led search for novel functional domains in MeCP2.

A one-step gene amplification system for use in cultured mammalian cells and transgenic animals

A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil

Comparative analysis of potential broad-spectrum neuronal Cre drivers

Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene.

CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

Domains of methylated CAC and CG target MeCP2 to tune transcription in the brain

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: inactivation of the mouse ERCC-1 gene

Kaiso-deficient mice show resistance to intestinal cancer

Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.

Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Stability of HPRT marker gene expression at different gene-targeted loci: observing and overcoming a position effect.

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

The role of MeCP2 in the brain.

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome