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List of works by Petr Kuzmic

A broad spectrum Kunitz type serine protease inhibitor secreted by the hookworm Ancylostoma ceylanicum.

scientific article published in September 2000

A detailed physical map of the 6p reading disability locus, including new markers and confirmation of recombination suppression

scientific article published on 13 August 2002

A generalized numerical approach to rapid-equilibrium enzyme kinetics: application to 17beta-HSD.

scientific article published on 20 December 2005

A generalized numerical approach to steady-state enzyme kinetics: applications to protein kinase inhibition.

scientific article published on 28 August 2009

A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin ⬇️

scientific article published on April 11, 2011

A steady state mathematical model for stepwise "slow-binding" reversible enzyme inhibition.

scientific article published on 28 November 2007

An algebraic model for the kinetics of covalent enzyme inhibition at low substrate concentrations

scientific article published on 27 November 2014

An algebraic model to determine substrate kinetic parameters by global nonlinear fit of progress curves.

scientific article published on 4 November 2016

Analysis of a dual domain phosphoglycosyl transferase reveals a ping-pong mechanism with a covalent enzyme intermediate.

scientific article

Application of the Van Slyke-Cullen irreversible mechanism in the analysis of enzymatic progress curves.

scientific article published on 21 July 2009

CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.

scientific article published in November 2013

CYP2E1 substrate inhibition. Mechanistic interpretation through an effector site for monocyclic compounds

scientific article published on 4 December 2007

Complexation between methyl viologen (paraquat) bis(hexafluorophosphate) and dibenzo[24]crown-8 revisited.

scientific article

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

scientific article published on 17 December 2013

DynaFit--a software package for enzymology.

scientific article

Effect of ribavirin and amantadine on early hepatitis C virus RNA rebound and clearance in serum during daily high-dose interferon.

scientific article published in January 2003

Fixed-point methods for computing the equilibrium composition of complex biochemical mixtures ⬇️

scientific article published on April 15, 1998

Fluorescence displacement method for the determination of receptor-ligand binding constants

scientific article published on August 15, 1992

Global analysis of protein-protein interactions reveals multiple CYP2E1-reductase complexes.

scientific article published on 09 August 2007

High-throughput screening of enzyme inhibitors: simultaneous determination of tight-binding inhibition constants and enzyme concentration

scientific article published on 01 November 2000

Homotropic cooperativity from the activation pathway of the allosteric ligand-responsive regulatory trp RNA-binding attenuation protein.

scientific article

Increase in fluorescence upon the hydrolysis of tyrosine peptides: application to proteinase assays

scientific article published on 01 May 1995

Inhibition of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis: Mechanism Revealed by Pre-Steady-State Kinetics

scientific article published on 19 August 2016

Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody

scientific article

Kinetic assay for HIV proteinase subunit dissociation.

scientific article published in March 1993

Kinetic determination of tight-binding impurities in enzyme inhibitors.

scientific article published in August 2003

Mechanical effects on the kinetics of the HIV proteinase deactivation

scientific article published on 01 April 1996

Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex.

scientific article published on 10 November 2003

Mixed-type noncompetitive inhibition of anthrax lethal factor protease by aminoglycosides

scientific article published on 01 July 2006

Mixtures of tight-binding enzyme inhibitors. Kinetic analysis by a recursive rate equation

scientific article published on January 1, 1992

Molecular characterization of Ancylostoma ceylanicum Kunitz-type serine protease inhibitor: evidence for a role in hookworm-associated growth delay.

scientific article published on April 2004

Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo.

scientific article published on 7 December 2001

Optimal design for the dose–response screening of tight-binding enzyme inhibitors ⬇️

scientific article published on July 25, 2011

Practical robust fit of enzyme inhibition data

scientific article

Sabellastarte magnifica Carboxypeptidase Inhibitor: The first Kunitz inhibitor simultaneously interacting with carboxypeptidases and serine proteases

scientific article published on 03 May 2018

Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases.

scientific article

Stabilization of HIV proteinase dimer by bound substrate.

scientific article published in July 1993

Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases

scientific article

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

scientific article published on 19 June 2017

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