List of works by Monique L den Boer

A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells

scientific article

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations

scientific article published on 11 December 2012

Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis

scientific article published on 15 June 2017

Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia

scientific article

Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1 driven B-cell precursor acute lymphoblastic leukemia

scholarly article by Roel Polak et al published 31 October 2018 in Haematologica

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

scientific article published on 21 August 2015

BCR-ABL1-like acute lymphoblastic leukaemia: From bench to bedside

scientific article

Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective

scientific article

Clinical and molecular genetic characterization of wild-type MLL infant acute lymphoblastic leukemia identifies few recurrent abnormalities

scientific article published on 17 December 2015

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.

scientific article published on 11 February 2017

Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia

D-HPLC analysis of the entire FLT3 gene in MLL rearranged and hyperdiploid acute lymphoblastic leukemia.

scientific article published in November 2007

Dasatinib in children and adolescents with relapsed or refractory leukemia: results of the CA180-018 phase I dose-escalation study of the Innovative Therapies for Children with Cancer Consortium

scientific article published on 28 May 2013

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia

scientific article

Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis

scientific article

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia

scientific article

Disturbed CXCR4/CXCL12 axis in paediatric precursor B-cell acute lymphoblastic leukaemia.

scientific article published on 4 April 2014

Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

scientific article

Enhancer Hijacking Drives Oncogenic <i>BCL11B</i> Expression in Lineage-Ambiguous Stem Cell Leukemia

publication published on 08 June 2021

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia

scientific article

Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.

scientific article

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols

scientific article

Expression profiling of adult acute lymphoblastic leukemia identifies a BCR-ABL1-like subgroup characterized by high non-response and relapse rates

scientific article published on 13 March 2015

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia

scientific article published in Scientific Reports

Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells

scientific article

Gene expression profiles associated with pediatric relapsed AML.

scientific article

Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia

scientific article published on November 2005

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]

scientific article published on September 2008

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

scientific article published on 28 September 2006

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

scientific article

Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia

scientific article published in August 2005

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

scientific article

Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL.

scientific article

High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).

scientific article published on 2 November 2010

High PDGFRA expression does not serve as an effective therapeutic target in ERG-deleted B-cell precursor acute lymphoblastic leukemia

scientific article published on 23 November 2017

High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia

scientific article published on 12 January 2018

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.

scientific article published on 3 June 2010

Hydrocortisone does not influence glucocorticoid sensitivity of acute lymphoblastic leukemia cells

scientific article published on 25 November 2014

Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale ⬇️

scientific article published on November 30, 2010

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

scientific article

Identification of apolipoprotein A-II in cerebrospinal fluid of pediatric brain tumor patients by protein expression profiling

scientific article

Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia

scientific article

Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteome-wide analysis

scientific article

In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia

scientific article published in January 2006

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 16 September 2017

Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL ⬇️

scientific article published on November 1, 2003

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

scientific article published on 03 December 2001

MicroRNA signature in BCR-ABL1-like and BCR-ABL1-positive childhood acute lymphoblastic leukemia: similarities and dissimilarities.

scientific article

Microarray-based identification of new targets for specific therapies in pediatric leukemia

scientific article published on June 2007

Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia

scientific article published on 20 February 2017

Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein ⬇️

scientific article published on January 1, 2004

New genetic abnormalities and treatment response in acute lymphoblastic leukemia

scientific article published on January 2009

Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.

scientific article published in October 2007

Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia

scientific article published on 14 August 2003

Role of mutation independent constitutive activation of FLT3 in juvenile myelomonocytic leukemia

scientific article published in November 2007

STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia

scientific article published on 5 June 2013

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

scientific article published on 14 November 2002

TELAML1-positive ALL: a discordant genotype.

scientific article published on 23 August 2005

Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia

scientific article

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

scientific article published on 27 September 2005

The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.

scientific article published in September 2006

The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

scientific article published on 18 October 2013

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance

scientific article published on 5 December 2014

Towards targeted therapy for infant acute lymphoblastic leukaemia

scientific article

Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

scientific article

Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia.

scientific article published on 22 November 2016

Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia

scientific article published on 23 February 2006

Various components of the insulin-like growth factor system in tumor tissue, cerebrospinal fluid and peripheral blood of pediatric medulloblastoma and ependymoma patients

scientific article

miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221

scientific article

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