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List of works by Chun-Wei Chen

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

scientific article published in February 2018

A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.

scientific article published in July 2017

A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens

scientific article published on 5 February 2024

ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner

scientific article published on 23 December 2022

An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia

scientific article published on 03 February 2022

Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

scientific article published on 22 May 2008

CAR T cells targeting BAFF-R can overcome CD19 antigen loss in B cell malignancies

scientific article published on 01 September 2019

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.

scientific article

Drugging Chromatin in Cancer: Recent Advances and Novel Approaches.

scientific article

Effects of culturing conditions on production of D-hydantoinase from recombinant Escherichia coli.

scientific article published in December 2004

High-resolution characterization of gene function using single-cell CRISPR tiling screen

scientific article published on 01 July 2021

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis

scientific article published on 15 February 2017

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

scientific article published on 04 November 2020

Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

scientific article published on 30 June 2020

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

scientific article published on 02 May 2016

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.

scientific article published on 15 November 2016

Nuclear phospholipid scramblase 1 prolongs the mitotic expansion of granulocyte precursors during G-CSF-induced granulopoiesis

scientific article

Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions

scientific article published on 15 May 2019

Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.

scientific article

Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond

scientific article

The role of DOT1L in the maintenance of leukemia gene expression.

scientific article published on 2 May 2016

Validation of a small molecule inhibitor of PDE6D-RAS interaction with favorable anti-leukemic effects

scientific article published on 14 April 2022

sAPPalpha enhances the transdifferentiation of adult bone marrow progenitor cells to neuronal phenotypes.

scientific article published in February 2006

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