List of works - Stephen M Todryk

A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine

scientific article

A natural immunization process prevents malaria.

scientific article published on 26 February 2010

A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens.

scientific article

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

scientific article

A protein fragment of streptococcal cell surface antigen I/II which prevents adhesion of Streptococcus mutans.

scientific article

A synthetic peptide adhesion epitope as a novel antimicrobial agent.

scientific article

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

scientific article published on 14 January 2019

Adoptive transfer of immature dendritic cells with autologous or allogeneic tumor cells generates systemic antitumor immunity

scientific article published on 01 June 1999

Allogeneic whole-tumour cell vaccination in the rat model of prostate cancer

scientific article published on 01 October 2000

An Intelligent Decision Support System for Leukaemia Diagnosis using Microscopic Blood Images.

scientific article

An adjuvant-modulated vaccine response in human whole blood

scientific article published on 12 June 2017

Anti-bacterial antibody and T cell responses in bronchiectasis are differentially associated with lung colonization and disease.

scientific article

Antibody and T cell responses against avian and microbial antigens associate with hypersensitivity pneumonitis disease parameters in pigeon breeders

scientific article published on 13 December 2019

Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships

scientific article

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.

scientific article published in June 2005

Building better T-cell-inducing malaria vaccines.

scientific article

CD40 ligation for immunotherapy of solid tumours

scientific article published on 01 February 2001

Can immunotherapy by gene transfer tip the balance against colorectal cancer?

scientific article

Characteristics of antibody responses in Pigeon Fanciers' Lung

scientific article published on 04 January 2013

Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector

scientific article published on 24 January 2012

Comparing human T cell and NK cell responses in viral-based malaria vaccine trials

scientific article

Correction: Correlation of Memory T Cell Responses against TRAP with Protection from Clinical Malaria, and CD4+ CD25high T Cells with Susceptibility in Kenyans.

scientific article published on 26 February 2011

Correction: Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial.

scientific article published on 26 February 2011

Corrigendum to “MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines” [J. Immunol. Methods 340 (2009) 33–41].

scientific article published in May 2011

Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class I expression in human prostate cancer cell lines: implications for gene therapy strategies.

scientific article published in January 2003

Cytokine gene transfection for autologous and allogeneic melanoma vaccines

scientific article published on 01 January 2001

Cytoplasmic delivery of antigens, by Bacillus subtilis enhances Th1 responses

scientific article published on 20 September 2008

Dendritic cells in Plasmodium infection.

scientific article published on June 2008

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells

scientific article published in September 2004

Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion.

scientific article published on March 2015

Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria

scientific article published on November 2005

Effect of route of immunisation and adjuvant on T and B cell epitope recognition within a streptococcal antigen.

scientific article published in January 1998

Efficacy of cytokine gene transfection may differ for autologous and allogeneic tumour cell vaccines.

scientific article published on February 2001

Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial

scientific article

Exercise-conditioned plasma attenuates nuclear concentrations of DNA methyltransferase 3B in human peripheral blood mononuclear cells

scientific article published on December 2015

Experimental mucosal induction of uveitis with the 60-kDa heat shock protein-derived peptide 336-351

scientific article published on 01 August 1998

Facets of heat shock protein 70 show immunotherapeutic potential.

scientific article

Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake

scientific article published on 01 August 1999

Heat shock protein derived from a non-autologous tumour can be used as an anti-tumour vaccine

scientific article published on 01 September 2003

Heat shock protein peptides reactive in patients with Behçet's disease are uveitogenic in Lewis rats

scientific article published on 01 August 1994

Heat shock proteins refine the danger theory

scientific article published on 01 March 2000

Heat-shock proteins as dendritic cell-targeting vaccines--getting warmer.

scientific article published on August 2013

Heated tumour cells of autologous and allogeneic origin elicit anti-tumour immunity.

scientific article

Hepatic expression of IL-15 mRNA is associated with liver graft acceptance.

scientific article

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area

scientific article published on 31 March 2006

Immunotherapeutic potential of whole tumour cells.

scientific article

Induction of immune responses to functional determinants of a cell surface streptococcal antigen

scientific article published on 01 January 1996

Innate lymphoid cells and fibrotic regulation

scientific article published on 24 August 2017

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

scientific article published in February 2016

MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines

scientific article published on 24 October 2008

MicroRNAs in the skin: role in development, homoeostasis and regeneration

scientific article

Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients

scientific article

Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity

scientific article

Potency assays for novel T-cell-inducing vaccines against malaria.

scientific article published on February 2009

Preclinical evaluation of "whole" cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes.

scientific article published in March 2000

Reduction of Glucocorticoid Receptor Function in Chronic Fatigue Syndrome.

scientific article

Safety, immunogenicity, and efficacy of prime-boost immunization with recombinant poxvirus FP9 and modified vaccinia virus Ankara encoding the full-length Plasmodium falciparum circumsporozoite protein

scientific article published on May 2006

Screening vaccine formulations for biological activity using fresh human whole blood

scientific article

Selective Expansion and Partial Activation of Human NK Cells and NK Receptor-Positive T Cells by IL-2 and IL-15

scientific article published on 01 September 2001

Significance of immunity against lung pathogens in untreated Parkinson's disease

scientific article published on 31 October 2013

Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells

scientific article published on July 2006

T Cell Memory to Vaccination

scientific article published on 14 December 2018

T-cell, adhesion, and B-cell epitopes of the cell surface Streptococcus mutans protein antigen I/II ⬇️

scientific article published on September 1, 1995

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.

scientific article

The biological effects of syngeneic and allogeneic cytokine-expressing prophylactic whole cell vaccines and the influence of irradiation in a murine melanoma model.

scientific article published on 13 September 2005

The immunotherapy of prostate cancer.

scientific article published in December 2000

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum

scientific article published on September 2007

The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming

scientific article published on September 2009

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression ⬇️

scientific article published on May 1, 1998

Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony-stimulating factor induces a local antitumour response and may generate systemic protective immunity.

scientific article

Viral vector vaccines make memory T cells against malaria.

scientific article published on June 2007

List of works by Stephen M Todryk

A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine

A natural immunization process prevents malaria.

A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens.

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

A protein fragment of streptococcal cell surface antigen I/II which prevents adhesion of Streptococcus mutans.

A synthetic peptide adhesion epitope as a novel antimicrobial agent.

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

Adoptive transfer of immature dendritic cells with autologous or allogeneic tumor cells generates systemic antitumor immunity

Allogeneic whole-tumour cell vaccination in the rat model of prostate cancer

An Intelligent Decision Support System for Leukaemia Diagnosis using Microscopic Blood Images.

An adjuvant-modulated vaccine response in human whole blood

Anti-bacterial antibody and T cell responses in bronchiectasis are differentially associated with lung colonization and disease.

Antibody and T cell responses against avian and microbial antigens associate with hypersensitivity pneumonitis disease parameters in pigeon breeders

Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.

Building better T-cell-inducing malaria vaccines.

CD40 ligation for immunotherapy of solid tumours

Can immunotherapy by gene transfer tip the balance against colorectal cancer?

Characteristics of antibody responses in Pigeon Fanciers' Lung

Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector

Comparing human T cell and NK cell responses in viral-based malaria vaccine trials

Correction: Correlation of Memory T Cell Responses against TRAP with Protection from Clinical Malaria, and CD4+ CD25high T Cells with Susceptibility in Kenyans.

Correction: Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial.

Corrigendum to “MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines” [J. Immunol. Methods 340 (2009) 33–41].

Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class I expression in human prostate cancer cell lines: implications for gene therapy strategies.

Cytokine gene transfection for autologous and allogeneic melanoma vaccines

Cytoplasmic delivery of antigens, by Bacillus subtilis enhances Th1 responses

Dendritic cells in Plasmodium infection.

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells

Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion.

Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria

Effect of route of immunisation and adjuvant on T and B cell epitope recognition within a streptococcal antigen.

Efficacy of cytokine gene transfection may differ for autologous and allogeneic tumour cell vaccines.

Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial

Exercise-conditioned plasma attenuates nuclear concentrations of DNA methyltransferase 3B in human peripheral blood mononuclear cells

Experimental mucosal induction of uveitis with the 60-kDa heat shock protein-derived peptide 336-351

Facets of heat shock protein 70 show immunotherapeutic potential.

Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake

Heat shock protein derived from a non-autologous tumour can be used as an anti-tumour vaccine

Heat shock protein peptides reactive in patients with Behçet's disease are uveitogenic in Lewis rats

Heat shock proteins refine the danger theory

Heat-shock proteins as dendritic cell-targeting vaccines--getting warmer.

Heated tumour cells of autologous and allogeneic origin elicit anti-tumour immunity.

Hepatic expression of IL-15 mRNA is associated with liver graft acceptance.

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area

Immunotherapeutic potential of whole tumour cells.

Induction of immune responses to functional determinants of a cell surface streptococcal antigen

Innate lymphoid cells and fibrotic regulation

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines

MicroRNAs in the skin: role in development, homoeostasis and regeneration

Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients

Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity

Potency assays for novel T-cell-inducing vaccines against malaria.

Preclinical evaluation of "whole" cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes.

Reduction of Glucocorticoid Receptor Function in Chronic Fatigue Syndrome.

Safety, immunogenicity, and efficacy of prime-boost immunization with recombinant poxvirus FP9 and modified vaccinia virus Ankara encoding the full-length Plasmodium falciparum circumsporozoite protein

Screening vaccine formulations for biological activity using fresh human whole blood

Selective Expansion and Partial Activation of Human NK Cells and NK Receptor-Positive T Cells by IL-2 and IL-15

Significance of immunity against lung pathogens in untreated Parkinson's disease

Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells

T Cell Memory to Vaccination

T-cell, adhesion, and B-cell epitopes of the cell surface Streptococcus mutans protein antigen I/II ⬇️

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.

The biological effects of syngeneic and allogeneic cytokine-expressing prophylactic whole cell vaccines and the influence of irradiation in a murine melanoma model.

The immunotherapy of prostate cancer.

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum

The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression ⬇️

Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony-stimulating factor induces a local antitumour response and may generate systemic protective immunity.

Viral vector vaccines make memory T cells against malaria.