List of works - Anthony J Sadler

ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton.

scientific article published on 27 March 2013

Auto-phosphorylation Represses Protein Kinase R Activity

scientific article published on 10 March 2017

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

scientific article

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

scientific article

Dynamic Flexibility of Double-stranded RNA Activated PKR in Solution

scientific article published on 05 April 2006

Dynamiting Viruses with MxA

scientific article published on 01 October 2011

Fine-tuning of the innate immune response by microRNAs.

scientific article published on 10 July 2007

Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion

scientific article published on 18 October 2010

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

scientific article

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling

scientific article

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

scientific article published on September 2009

Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.

scientific article published on 17 November 2014

Orchestration of the activation of protein kinase R by the RNA-binding motif.

scientific article published on April 2010

Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity

scientific article published on 11 June 2009

Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA.

scientific article published on 14 July 2008

Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense ⬇️

scientific article published on May 25, 2012

Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.

scientific article

Structure and function of the protein kinase R.

scientific article published on January 2007

The 15:17 to Paris: The True Story of a Terrorist, a Train, and Three American Heroes

2016 book

The Role of Protein Kinase R in the Interferon Response ⬇️

scientific article published on December 19, 2010

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.

scientific article published on 13 April 2015

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

scientific article

The kinase activity of PKR represses inflammasome activity

scientific article published on 22 January 2016

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

scientific article

The role of MDA5 in the development of autoimmune disease.

scientific article published on 3 October 2017

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.

scientific article

List of works by Anthony J Sadler

ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton.

Auto-phosphorylation Represses Protein Kinase R Activity

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

Dynamic Flexibility of Double-stranded RNA Activated PKR in Solution

Dynamiting Viruses with MxA

Fine-tuning of the innate immune response by microRNAs.

Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.

Orchestration of the activation of protein kinase R by the RNA-binding motif.

Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity

Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA.

Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense ⬇️

Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.

Structure and function of the protein kinase R.

The 15:17 to Paris: The True Story of a Terrorist, a Train, and Three American Heroes

The Role of Protein Kinase R in the Interferon Response ⬇️

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

The kinase activity of PKR represses inflammasome activity

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

The role of MDA5 in the development of autoimmune disease.

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.