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List of works by Jonathan Dordick

3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity

scientific article published on 21 July 2021

A GFP complementation system for monitoring and directing nanomaterial mediated protein delivery to human cellular organelles

scientific article published in December 2010

A combinatorial biocatalysis approach to an array of cholic acid derivatives

scientific article

A purification process for heparin and precursor polysaccharides using the pH responsive behavior of chitosan

scientific article

A rewired green fluorescent protein: folding and function in a nonsequential, noncircular GFP permutant

scientific article published on 3 December 2010

A strategy for in vivo screening of subtilisin E reaction specificity in E. coli periplasm

scientific article

Active-site motions and polarity enhance catalytic turnover of hydrated subtilisin dissolved in organic solvents

scientific article

Addressing endotoxin issues in bioengineered heparin

scientific article published on 18 October 2012

Advancing Predictive Hepatotoxicity at the Intersection of Experimental, in Silico, and Artificial Intelligence Technologies

scientific article published on 10 May 2018

Analysis of E. coli K5 capsular polysaccharide heparosan

scientific article

Analysis of Heparins Derived From Bovine Tissues and Comparison to Porcine Intestinal Heparins

scientific article published on 14 April 2016

Analysis of glycosaminoglycans in stem cell glycomics ⬇️

scientific article published on January 1, 2011

Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol

scientific article published on 24 June 2015

Antistaphylococcal nanocomposite films based on enzyme-nanotube conjugates

scientific article (publication date: 27 July 2010)

Apocynin derivatives interrupt intracellular signaling resulting in decreased migration in breast cancer cells

scientific article published on January 2006

Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways

scientific article published on 23 November 2010

Artificial organelles: digital microfluidic platform for proteoglycan and glycoprotein biosynthesis.

scientific article

Assays for determining heparan sulfate and heparin O-sulfotransferase activity and specificity

scientific article published on 23 November 2013

Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform

scientific article published in November 2004

Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism

scientific article published on 23 March 2016

Binding domains of Bacillus anthracis phage endolysins recognize cell culture age-related features on the bacterial surface

scientific article

Biocatalyst activity in nonaqueous environments correlates with centisecond-range protein motions

scholarly article

Biocatalytic Polytransesterification of Inulin with Divinyladipate

scientific article published in October 2002

Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential

scientific article published on 29 October 2013

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels

scientific article published in March 2004

Bioinformatics-driven, rational engineering of protein thermostability

scientific article published on 26 September 2006

Bionanoconjugate‐based composites for decontamination of nerve agents ⬇️

scientific article published on September 21, 2010

Carbon nanotube-induced loss of multicellular chirality on micropatterned substrate is mediated by oxidative stress

scientific article published on 27 February 2014

Cell-Based Assay Design for High-Content Screening of Drug Candidates

scientific article

Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages

scientific article published on 09 January 2014

Characterization of AmiBA2446, a Novel Bacteriolytic Enzyme Active against Bacillus Species ⬇️

scientific article published on July 19, 2013

Characterization of the activity of the spore cortex lytic enzyme CwlJ1.

scientific article published on 25 February 2015

Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands

scientific article

Chip-based polyketide biosynthesis and functionalization

scientific article published in July 2006

Combinatorial formulation of biocatalyst preparations for increased activity in organic solvents: salt activation of penicillin amidase

scientific article published in March 2004

Combinatorial one-pot chemoenzymatic synthesis of heparin

scientific article

Comparative void-volume analysis of psychrophilic and mesophilic enzymes: Structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility ⬇️

scientific article published on October 20, 2011

Complete biosynthesis of a sulfated chondroitin in Escherichia coli

scientific article published in 2021

Compression-modulated tunable-pore carbon-nanotube membrane filters

scientific article published in April 2007

Conductive Cable Fibers with Insulating Surface Prepared by Coaxial Electrospinning of Multiwalled Nanotubes and Cellulose ⬇️

scientific article published on September 13, 2010

Control of the heparosan N-deacetylation leads to an improved bioengineered heparin ⬇️

scientific article published on April 12, 2011

Controlled hierarchical assembly of switchable DNA-multiprotein complexes

scientific article published in June 2006

Controlled photochemical depolymerization of K5 heparosan, a bioengineered heparin precursor ⬇️

scientific article published on August 1, 2011

Cytochrome C on silica nanoparticles: influence of nanoparticle size on protein structure, stability, and activity.

scientific article

Detection of cerebrospinal fluid leakage by specific measurement of transferrin glycoforms

scientific article published on 19 August 2015

Development of a fluorescence-based, ultra high-throughput screening platform for nanoliter-scale cytochrome p450 microarrays

scientific article

Direct solubilization of enzyme aggregates with enhanced activity in nonaqueous media

scientific article published in April 2007

Directed assembly of carbon nanotubes at liquid-liquid interfaces: nanoscale conveyors for interfacial biocatalysis

scientific article published in February 2006

E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor

scientific article

ENZYMATIC POLYMERIZATION OF PHENOLS IN ROOM TEMPERATURE IONIC LIQUIDS.

scientific article published on July 2009

Editorial overview: Nanobiotechnology

scientific article published in July 2014

Effect of eliminase gene (elmA) deletion on heparosan production and shedding in Escherichia coli K5 ⬇️

scientific article published on April 11, 2013

Effect of gold nanoparticle morphology on adsorbed protein structure and function ⬇️

scientific article published on June 25, 2011

Effect of gold nanoparticle structure on the conformation and function of adsorbed proteins ⬇️

scientific article published on August 17, 2012

Electrospinning of Nanomaterials and Applications in Electronic Components and Devices

scientific article published on September 1, 2010

Elmer L. Gaden, Jr. Tribute ⬇️

scientific article published on October 1, 2012

Engineered heparins as new anticoagulant drugs

scientific article published on 21 November 2016

Engineering of molecular and cellular biocatalysts: selected contributions by James E. Bailey

scientific article published on September 2002

Engineering of routes to heparin and related polysaccharides

scientific article

Enhanced stability of enzymes adsorbed onto nanoparticles

scientific article published in April 2007

Enhancing protein stability by adsorption onto raftlike lipid domains

scientific article published on May 2009

Enzymatic Reactions in Liquid and Solid Paraffins: Application for Enzyme–Based Temperature Abuse Sensors

scientific article published in November 1986

Enzymatic synthesis of dextran-containing hydrogels

scientific article published in October 2002

Enzymatic synthesis of glycosaminoglycan heparin

scientific article published on July 2007

Enzymatic synthesis of inulin-containing hydrogels

scientific article published in March 2002

Enzyme activation for nonaqueous media

scientific article

Enzyme activation for organic solvents made easy

scientific article

Enzyme-Based Listericidal Nanocomposites ⬇️

scientific article published on January 1, 2013

Enzyme-Immobilized Chitosan Nanoparticles as Environmentally Friendly and Highly Effective Antimicrobial Agents

scientific article published on 16 May 2019

Enzyme-based formulations for decontamination: current state and perspectives ⬇️

scientific article published on March 10, 2013

Enzyme-carbon nanotube conjugates in room-temperature ionic liquids

scientific article published in November 2007

Enzyme-driven Bacillus spore coat degradation leading to spore killing

scientific article published on 6 November 2013

Escherichia coliK5 heparosan fermentation and improvement by genetic engineering ⬇️

scientific article published on January 1, 2011

Expanding nature's small molecule diversity via in vitro biosynthetic pathway engineering ⬇️

scientific article published on 05 March 2012

Expanding the Scope of Biocatalysis: Oxidative Biotransformations on Solid‐Supported Substrates ⬇️

scientific article published on July 7, 2008

Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation

scientific article published in January 2005

Exploring embryonic stem cell fate using cellular microarrays

Exposure to carbon nanotubes leads to changes in the cellular biomechanics

journal article published in 2013

Expression of low endotoxin 3-O-sulfotransferase in Bacillus subtilis and Bacillus megaterium

scientific article published on 4 August 2013

FGF-FGFR signaling mediated through glycosaminoglycans in microtiter plate and cell-based microarray platforms

scientific article

Fabrication of enzyme-based coatings on intact multi-walled carbon nanotubes as highly effective electrodes in biofuel cells

scientific article

Fibroblast growth factor-based signaling through synthetic heparan sulfate blocks copolymers studied using high cell density three-dimensional cell printing

scientific article published on 22 February 2014

Finding melanoma drugs through a probabilistic knowledge graph

Finding melanoma drugs through a probabilistic knowledge graph

Flexible Peptide Linkers Enhance the Antimicrobial Activity of Surface Immobilized Bacteriolytic Enzymes

scientific article published on 16 October 2018

Functional nanoscale biomolecular materials ⬇️

scientific article published on November 29, 2012

Gene Delivery in Three-Dimensional Cell Cultures by Superparamagnetic Nanoparticles ⬇️

scientific article published on August 24, 2010

Glycosaminoglycan Compositional Analysis of Relevant Tissues in ZIKV Pathogenesis and in vitro Evaluation of Heparin as Antiviral Against ZIKV Infection

article

Glycosaminoglycans in infectious disease

scientific article published on 29 March 2013

Growth inhibition of Mycobacterium smegmatis by mycobacteriophage-derived enzymes

scientific article published on 9 May 2014

Heparin and anticoagulation.

scientific article published on June 2016

Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers

scientific article published on 01 October 2020

High cell density cultivation of a recombinant E. coli strain expressing a key enzyme in bioengineered heparin production ⬇️

scientific article published on January 15, 2013

High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin

scientific article

High sensitivity detection of active botulinum neurotoxin by glyco-quantitative polymerase chain-reaction

scientific article published on 24 February 2014

High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform

scientific article published on 27 October 2016

High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening

scientific article

High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research

scientific article published on 03 May 2009

High-throughput combinatorial screening reveals interactions between signaling molecules that regulate adult neural stem cell fate

scientific article published on 06 November 2018

High-throughput human metabolism and toxicity analysis

scientific article published on 12 October 2006

High-throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture

scientific article published on 27 October 2018

High-throughput screening and quantitative structure-efficacy relationship models of potential displacer molecules for ion-exchange systems

scientific article

High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction

scientific article published on 25 May 2007

Highly Enantioselective Oxidation of cis-Cyclopropylmethanols to Corresponding Aldehydes Catalyzed by Chloroperoxidase ⬇️

scientific article published on January 11, 2002

Highly active and stable DNAzyme-carbon nanotube hybrids

scientific article published in September 2005

High‐Throughput Transfection of Interfering RNA into a 3D Cell‐Culture Chip ⬇️

scientific article published on April 17, 2012

How interfaces affect hydrophobically driven polymer folding

scientific article published in April 2009

Human parvovirus B19 virus-like particles: In vitro assembly and stability ⬇️

scientific article published on December 14, 2011

Hydration of enzyme in nonaqueous media is consistent with solvent dependence of its activity

scientific article

Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins

scientific article published in May 2002

Identifying Specific Protein Residues That Guide Surface Interactions and Orientation on Silica Nanoparticles ⬇️

scientific article published on August 15, 2013

Immobilized enzymes to convert N-sulfo, N-acetyl heparosan to a critical intermediate in the production of bioengineered heparin ⬇️

scientific article published on 05 July 2013

Improved strategies for electrochemical 1,4-NAD(P)H2 regeneration: A new era of bioreactors for industrial biocatalysis

scientific article published on 10 October 2017

In vitro gene expression-coupled bacterial cell chip for screening species-specific antimicrobial enzymes

scientific article published on 28 March 2017

In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents

scientific article published on September 2009

In vitro transcription and protein translation from carbon nanotube-DNA assemblies

scientific article published in June 2006

Increasing protein stability through control of the nanoscale environment

scientific article

Influence of a three-dimensional, microarray environment on human Cell culture in drug screening systems ⬇️

scientific article published on September 19, 2012

Influence of circadian rhythm on drug metabolism in 3D hepatic spheroids

scientific article published in 2022

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

scientific article published in January 2002

Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols

scientific article published on 30 May 2009

Interaction of Zika Virus Envelope Protein with Glycosaminoglycans

scientific article

Investigation of DNA-binding properties of an aminoglycoside-polyamine library using quantitative structure-activity relationship (QSAR) models

scientific article published in November 2005

Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis

scientific article

Kinesin I ATPase Manipulates Biohybrids Formed from Tubulin and Carbon Nanotubes ⬇️

scientific article published on January 1, 2011

Laccase- and chloroperoxidase-nanotube paint composites with bactericidal and sporicidal activity ⬇️

scientific article published on February 24, 2012

Lipid-based nanotubes as functional architectures with embedded fluorescence and recognition capabilities

scientific article

Mass balance analysis of contaminated heparin product

scientific article

Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues ⬇️

scientific article published on May 17, 2013

Metabolic enzyme microarray coupled with miniaturized cell-culture array technology for high-throughput toxicity screening

scientific article (publication date: 2010)

Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses

scientific article

Metal-Organic Framework-Based Composite for Photocatalytic Detection of Prevalent Pollutant

scientific article published on 15 August 2019

Microarray platform affords improved product analysis in mammalian cell growth studies

scientific article

Microfluidic peroxidase biochip for polyphenol synthesis

scientific article

Modular Assembly of Unique Chimeric Lytic Enzymes on a Protein Scaffold Possessing Anti-Staphylococcal Activity

scientific article published on 26 September 2019

Molecular Mass Characterization of Glycosaminoglycans with Different Degrees of Sulfation in Bioengineered Heparin Process by Size Exclusion Chromatography ⬇️

scientific article published on October 1, 2012

Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase.

scientific article

Molecular imprinting of enzymes with water-insoluble ligands for nonaqueous biocatalysis

scientific article

Multienzyme catalysis in microfluidic biochips

scientific article published in July 2003

Multiplexed amino acid array utilizing bioluminescent Escherichia coli auxotrophs

scientific article

Nanoparticle-mediated cytoplasmic delivery of proteins to target cellular machinery

scientific article

Nanostructured glycan architecture is important in the inhibition of influenza A virus infection.

scientific article

Nanotubes in biological applications

scientific article

Newly identified bacteriolytic enzymes that target a wide range of clinical isolates of Clostridium difficile

scientific article published on 04 June 2016

Nonaqueous biocatalytic synthesis of new cytotoxic doxorubicin derivatives: exploiting unexpected differences in the regioselectivity of salt-activated and solubilized subtilisin

scientific article published on March 2002

Opportunities for broadening the application of cell wall lytic enzymes

scientific article published on 18 September 2020

Osmolyte trimethylamine-N-oxide does not affect the strength of hydrophobic interactions: origin of osmolyte compatibility

scientific article

Ozonolysis of the double bond of the unsaturated uronate residue in low-molecular-weight heparin and K5 heparosan ⬇️

scientific article published on June 22, 2011

Periplasmic expression as a basis for whole cell kinetic screening of unnatural enzyme reactivities

scientific article published in January 2004

Plasmonic activation of gold nanorods for remote stimulation of calcium signaling and protein expression in HEK 293T cells

scientific article

Polymer-nanotube-enzyme composites as active antifouling films

scientific article published in January 2007

Polyphenolic glycosides and aglycones utilize opposing pathways to selectively remodel and inactivate toxic oligomers of amyloid β.

scientific article published on 10 June 2011

Position-Specific Chemical Modification and Quantitative Proteomics Disclose Protein Orientation Adsorbed on Silica Nanoparticles ⬇️

scientific article published on February 9, 2012

Predicting amino acid residues responsible for enzyme specificity solely from protein sequences

scientific article

Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays

scientific article published on 22 November 2017

Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway

scientific article

Protein immobilization in hollow nanostructures and investigation of the adsorbed protein behavior.

scientific article

Protein-assisted solubilization of single-walled carbon nanotubes

scientific article published in February 2006

Proteoglycans in stem cells

scientific article published on 28 February 2012

Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice

scientific article

Rapid and quantitative measurement of metabolic stability without chromatography or mass spectrometry

scientific article

Recent advances in sulfotransferase enzyme activity assays

scientific article

Recent progress and applications in glycosaminoglycan and heparin research

scientific article published on 24 September 2009

Reducing Staphylococcus aureus resistance to lysostaphin using CRISPR-dCas9

scientific article published on 03 September 2019

Regulation of stem cell signaling by nanoparticle-mediated intracellular protein delivery ⬇️

scientific article published on February 5, 2011

Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles

scientific article

Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin ⬇️

scientific article published on September 10, 2011

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

scientific article published on 28 May 2010

Room temperature ionic liquids as emerging solvents for the pretreatment of lignocellulosic biomass ⬇️

scientific article published on June 1, 2011

Selective Killing of Pathogenic Bacteria by Antimicrobial Silver Nanoparticle-Cell Wall Binding Domain Conjugates.

scientific article published on 5 April 2018

Selective antimicrobial activity of cell lytic enzymes in a bacterial consortium

scientific article published on 15 June 2019

Selective characterization of proteins on nanoscale concave surfaces

scientific article published on 22 October 2015

Si nanocolumns as novel nanostructured supports for enzyme immobilization

scientific article published in December 2003

Signal Amplification by Glyco‐qPCR for Ultrasensitive Detection of Carbohydrates: Applications in Glycobiology ⬇️

scientific article published on October 16, 2012

Signal amplification of target protein on heparin glycan microarray

scientific article published on 06 August 2008

Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme.

scientific article

Silica-immobilized enzymes for multi-step synthesis in microfluidic devices

scientific article published in October 2007

Simultaneous in vitro protein synthesis using solid-phase DNA template

scientific article published in November 2004

Single enzyme nanoparticles armored by a thin silicate network: Single enzyme caged nanoparticles

Solid-phase chemoenzymatic synthesis of C-sialosides

scientific article published in October 2004

Solid-phase peptide synthesis by ion-paired alpha-chymotrypsin in nonaqueous media

scientific article

Spaceflight promotes biofilm formation by Pseudomonas aeruginosa

scientific article published in 2013

Stem cell behavior on tailored porous oxide surface coatings.

scientific article

Structural characterization of heparins from different commercial sources ⬇️

scientific article published on September 20, 2011

Structural diversity of peroxidase-catalyzed oxidation products of o-methoxyphenols

scientific article published in June 2004

Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells

scientific article published on 2 October 2012

Structure and function of enzymes adsorbed onto single-walled carbon nanotubes.

scientific article

Structure, function, and stability of enzymes covalently attached to single-walled carbon nanotubes

scientific article published on 18 October 2007

Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro

scientific article published on 24 July 2020

The lipase-catalyzed hydrolysis of lutein diesters in non-aqueous media is favored at extremely low water activities

article

Three dimensional cellular microarray platform for human neural stem cell differentiation and toxicology

scientific article

Three-dimensional cell culture microarray for high-throughput studies of stem cell fate

scientific article published on May 2010

Three-dimensional cellular microarray for high-throughput toxicology assays

scholarly article

Toward an artificial Golgi: redesigning the biological activities of heparan sulfate on a digital microfluidic chip

scientific article

Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase ⬇️

scientific article published on December 29, 2011

Two-Step Enzymatic Modification of Solid-Supported Bergenin in Aqueous and Organic Media

scientific article

Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis ⬇️

scientific article published on April 15, 2011

Unfolding of ribonuclease A on silica nanoparticle surfaces.

scientific article

Unnatural polyketide analogues selectively target the HER signaling pathway in human breast cancer cells

scientific article

Unprotonated Short-Chain Alkylamines Inhibit Staphylolytic Activity of Lysostaphin in a Wall Teichoic Acid-Dependent Manner

scientific article published on 02 July 2018

Wall Teichoic Acids Are Involved in the Medium-Induced Loss of Function of the Autolysin CD11 against Clostridium difficile

scientific article published on 19 October 2016

Water dynamics and salt-activation of enzymes in organic media: mechanistic implications revealed by NMR spectroscopy

scientific article published on 3 April 2006

Water-soluble carbon nanotube-enzyme conjugates as functional biocatalytic formulations

scientific article published in December 2006

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