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List of works by Jonathan Clayden

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The challenge of atropisomerism in drug discovery

scientific article
Transmission of stereochemical information over nanometre distances in chemical reactions

scientific article published on 08 December 2008
Asymmetric synthesis of tertiary thiols and thioethers

scientific article published on 10 May 2011
Quaternary centres bearing nitrogen (α-tertiary amines) as products of molecular rearrangements.

scientific article published on 07 March 2011
Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer

scientific article published in Science
Foldamer-Mediated Remote Stereocontrol: >1,60 Asymmetric Induction

scientific article (publication date: 8 November 2013)
Dynamic foldamer chemistry

scientific article
N-versus C-terminal control over the screw-sense preference of the configurationally achiral, conformationally helical peptide motif Aib(8)GlyAib(8).

scientific article published in April 2010
Ultra-remote stereocontrol by conformational communication of information along a carbon chain

scientific article published on 01 October 2004
Reproducibility of tract segmentation between sessions using an unsupervised modelling-based approach

scientific article
Length-Dependent Formation of Transmembrane Pores by 310-Helical α-Aminoisobutyric Acid Foldamers

scientific article published on 23 December 2015
Barriers to rotation about the chiral axis of tertiary aromatic amides

article by Anjum Ahmed et al published October 1998 in Tetrahedron
End-to-end conformational communication through a synthetic purinergic receptor by ligand-induced helicity switching

scientific article published on 15 September 2013
Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas

scientific article
The Twisted Amide 2-Quinuclidone: 60 Years in the Making

scientific article published on 01 November 2006
Left-handed helical preference in an achiral peptide chain is induced by an L-amino acid in an N-terminal type II β-turn

scientific article published on 22 January 2013
Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond

scientific article published on 14 January 2016
Helix persistence and breakdown in oligoureas of metaphenylenediamine: apparent diastereotopicity as a spectroscopic marker of helix length in solution

scientific article
Lithium-sulfoxide-lithium exchange for the asymmetric synthesis of atropisomers under thermodynamic control

scientific article
Atropisomeric Amides as Chiral Ligands: Using (−)-Sparteine-Directed Enantioselective Silylation to Control the Conformation of a Stereogenic Axis

scientific article published on 01 October 2000
Engineering the structure of an N-terminal β-turn to maximize screw-sense preference in achiral helical peptide chains

scientific article published on 24 April 2014
Anionic cyclisations of an N-benzyl naphthamide: a route to benzo[e]isoindolones

Diastereotopic fluorine substituents as 19F NMR probes of screw-sense preference in helical foldamers

scientific article published on 5 April 2013
Slow interconversion of enantiomeric conformers or atropisomers of anilide and urea derivatives of 2-substituted anilines.

scientific article published on 26 July 2005
Quantifying End-to-End Conformational Communication of Chirality through an Achiral Peptide Chain

scientific article published on 01 January 2009
Stereochemical relays: communication via conformation

scientific article published on 15 June 2006
Induction of Unexpected Left-Handed Helicity by an N-Terminal L-Amino Acid in an Otherwise Achiral Peptide Chain

scientific article published on 03 January 2012
The synthesis of (-)-isodomoic acid C.

scientific article
Flaws in foldamers: conformational uniformity and signal decay in achiral helical peptide oligomers

scientific article published on 21 January 2015
Substituted Diarylmethylamines by Stereospecific Intramolecular Electrophilic Arylation of Lithiated Ureas

scientific article published on 24 May 2007
Stereocontrol with Rotationally Restricted Amides

Atroposelectivity in the reactions of ortholithiated aromatic tertiary amides with aldehydes

article published in 1997
Asymmetric induction using atropisomers: Diastereoselective additions to 2-acyl-1-naphthamides

article
Thionoglycine as a multifunctional spectroscopic reporter of screw-sense preference in helical foldamers

scientific article published on 12 December 2013
Conformational Switching of a Foldamer in a Multicomponent System by pH-Filtered Selection between Competing Noncovalent Interactions

scientific article published on 14 May 2015
α-Pyridylation of Chiral Amines via Urea Coupling, Lithiation and Rearrangement

scientific article published on 22 July 2008
Non-Biaryl Atropisomers: New Classes of Chiral Reagents, Auxiliaries, and Ligands?

Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution.

scientific article published in April 2009
Dearomatising cyclisations of lithiated N-benzylbenzamides

Stereodynamics of bond rotation in tertiary aromatic amides

scientific article published in March 2002
Enantioselective Synthesis of Atropisomeric Amides by Dynamic Resolution: Thermodynamic Control with a Proline-Derived Diamine Resolving Agent

scientific article published on 01 September 1999
Biocatalytic desymmetrization of an atropisomer with both an enantioselective oxidase and ketoreductases.

scientific article published on September 2010
Conformationally Interlocked Amides: Remote Asymmetric Induction by Mechanical Transfer of Stereochemical Information

article by Jonathan Clayden et al published January 1998 in Tetrahedron Letters
Helical Foldamers Incorporating Photoswitchable Residues for Light-Mediated Modulation of Conformational Preference

scientific article published on 16 June 2016
Atroposelectivity in the Reactions of Laterally Lithiated Tertiary Amides

article by Jonathan Clayden & Jennifer H. Pink published April 1997 in Tetrahedron Letters
Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

scientific article published on 24 January 2014
Synthesis of (±)-kainic acid by dearomatising cyclisation of a lithiated N-benzyl p-anisamide

Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides

scientific article published on 14 October 2003
Measuring Screw-Sense Preference in a Helical Oligomer by Comparison of13C NMR Signal Separation at Slow and Fast Exchange

scientific article published on 25 February 2011
Nanometer-Range Communication of Stereochemical Information by Reversible Switching of Molecular Helicity

scientific article published on 01 September 2010

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