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List of works by Nicholas Furnham

Abstracting knowledge from the protein data bank ⬇️

scientific article published on September 29, 2012

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

scientific article

Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

scientific article published on 19 April 2018

CATH: comprehensive structural and functional annotations for genome sequences.

scientific article

Chopping and Changing: the Evolution of the Flavin-dependent Monooxygenases

scientific article

Comparative modelling by restraint-based conformational sampling

scientific article

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity

scientific article published on 29 October 2015

Complementary Sources of Protein Functional Information: The Far Side of GO.

scientific article published on January 2017

Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents

scientific article published on 22 October 2018

Conformer generation under restraints

scientific article

Current challenges in genome annotation through structural biology and bioinformatics ⬇️

scientific article published on 09 August 2012

Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening

scientific article

EC-BLAST: a tool to automatically search and compare enzyme reactions

scientific article

Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function

scientific article published on 01 January 2019

Exploring the biological and chemical complexity of the ligases

scientific article

Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies

scientific article

Extending CATH: increasing coverage of the protein structure universe and linking structure with function

scientific article

FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies

scientific article

FunTree: advances in a resource for exploring and contextualising protein function evolution

scientific article

Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis

scientific article

Knowledge-based real-space explorations for low-resolution structure determination.

scientific article

Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection

scientific article

Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies

scientific article published on 13 November 2015

Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites

scientific article published on 2 November 2017

Missing in action: enzyme functional annotations in biological databases

scientific article published on August 2009

Model-building strategies for low-resolution X-ray crystallographic data

scientific article

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

scientific article

QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni

scientific article published on 02 June 2016

Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence

publication published on 31 May 2021

Splice variants: a homology modeling approach

scientific article published in February 2004

Structural basis for inhibition of homologous recombination by the RecX protein

scientific article

Structure and mechanism of drug efflux machinery in Gram negative bacteria

scientific article published on September 2008

Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode

scientific article published on 18 January 2006

The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes

scientific article

The Classification and Evolution of Enzyme Function

scientific article

The NAD Binding Domain and the Short-Chain Dehydrogenase/Reductase (SDR) Superfamily

The evolution of enzyme function in the isomerases

scientific article

To what extent do structural changes in catalytic metal sites affect enzyme function?

scientific article published on 8 November 2017

Understanding enzyme function evolution from a computational perspective

scientific article published on 7 September 2017

Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis

scientific article published in Scientific Reports

Unveiling the Kinomes of and Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

scientific article published on 08 February 2019

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