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List of works by Chad J Roy

A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates.

scientific article published on 9 December 2017

A Burkholderia pseudomallei outer membrane vesicle vaccine provides protection against lethal sepsis

scientific article

A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus.

scientific article published on 16 January 2013

A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection ⬇️

scientific article published on August 24, 2011

A smartphone-read ultrasensitive and quantitative saliva test for COVID-19

scientific article published on 11 December 2020

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

scientific article published on 01 May 2019

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.

scientific article

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

scientific article published on 19 April 2021

Adverse event following live attenuated chikungunya vaccine in a cynomolgus macaque with pre-existing chronic hydrocephalus

scientific article published on 03 April 2019

Aerobiology and inhalation exposure to biological select agents and toxins.

scientific article published on 03 August 2010

Aerogenic vaccination with a Burkholderia mallei auxotroph protects against aerosol-initiated glanders in mice.

scientific article published in March 2005

Aerosol-induced brucellosis increases TLR-2 expression and increased complexity in the microanatomy of astroglia in rhesus macaques

scientific article published on 02 December 2013

Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model.

scientific article published in March 2012

Aerosolized gentamicin reduces the burden of tuberculosis in a murine model.

scientific article published on 5 December 2011

Animal models for COVID-19

scientific article published on 23 September 2020

Animal models of ricin toxicosis

scientific article

CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.

scientific article published on 06 September 2016

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

scientific article published on 27 November 2020

Challenges and Practices in Building and Implementing Biosafety and Biosecurity Programs to Enable Basic and Translational Research with Select Agents.

scientific article

Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models

scientific article published on 6 March 2018

Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose.

scientific article

Chimeric plantibody passively protects mice against aerosolized ricin challenge

scientific article

Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin

scientific article published on 9 June 2015

Comparative dynamic aerosol efficiencies of three emergent coronaviruses and the unusual persistence of SARS-CoV-2 in aerosol suspensions

scientific article published on 18 April 2020

Comparative in vitro effectiveness of a novel contact lens multipurpose solution on Acanthamoeba castellanii

article

Comparative study of lung cytologic features in normal rhesus (Macaca mulatta), cynomolgus (Macaca fasicularis), and African green (Chlorocebus aethiops) nonhuman primates by use of bronchoscopy.

scientific article published in August 2004

Conservation of CD1 intracellular trafficking patterns between mammalian species.

scientific article published in December 2002

Design of an environmentally controlled rotating chamber for bioaerosol aging studies

scientific article

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin

scientific article published on 9 May 2016

Differential susceptibility of inbred mouse strains to Burkholderia thailandensis aerosol infection

scientific article

Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development

scientific article

Effective Treatment of Staphylococcal Enterotoxin B Aerosol Intoxication in Rhesus Macaques by Using Two Parenterally Administered High-Affinity Monoclonal Antibodies

scientific article published on 25 April 2019

Evaluation of a Burkholderia pseudomallei Outer Membrane Vesicle Vaccine in Nonhuman Primates

scientific article

Evaluation of inhaled cidofovir as postexposure prophylactic in an aerosol rabbitpox model.

scientific article

Genetic requirements for the survival of tubercle bacilli in primates

scientific article

High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation in Simian Immunodeficiency Virus-Infected Rhesus Macaques.

scientific article published on 8 February 2018

Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B

scientific article

Immunologic characterization of a rhesus macaque H1N1 challenge model for candidate influenza virus vaccine assessment.

scientific article

Immunospecific Responses to Bacterial Elongation Factor Tu during Burkholderia Infection and Immunization ⬇️

scientific article published on December 17, 2010

Impact of Inhalation Exposure Modality and Particle Size on the Respiratory Deposition of Ricin in BALB/c Mice ⬇️

scientific article published on May 1, 2003

Infectious disease aerobiology: miasma incarnate.

scientific article published on 19 December 2012

Intranasal administration of dry powder anthrax vaccine provides protection against lethal aerosol spore challenge.

scientific article

Lung Expression of Human ACE2 Sensitizes the Mouse to SARS-CoV-2 Infection

scientific article published on 29 September 2020

MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques

scientific article published on 27 February 2024

Mucosal bacterial dissemination in a rhesus macaque model of experimental brucellosis

scientific article published on 2 June 2017

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis

scientific article

Mucosal vaccines for biodefense.

scientific article published on January 2012

Neuropathogenesis of Chikungunya infection: astrogliosis and innate immune activation

scientific article published on 29 September 2015

Oropharyngeal aspiration of ricin as a lung challenge model for evaluation of the therapeutic index of antibodies against ricin A-chain for post-exposure treatment.

scientific article published on October 2007

Pathogenesis of aerosolized Eastern Equine Encephalitis virus infection in guinea pigs

scientific article published on 23 October 2009

Phenotypic and Kinetic Changes of Myeloid Lineage Cells in Innate Response to Chikungunya Infection in Cynomolgus Macaques

scientific article published in 2022

Pirfenidone blocks the in vitro and in vivo effects of staphylococcal enterotoxin B

scientific article

Post-exposure therapeutic efficacy of COX-2 inhibition against Burkholderia pseudomallei

scientific article (publication date: 2013)

Prevention and treatment of Clostridium perfringens epsilon toxin intoxication in mice with a neutralizing monoclonal antibody (c4D7) produced in Nicotiana benthamiana.

scientific article

Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens.

scientific article

Protection of non-human primates against glanders with a gold nanoparticle glycoconjugate vaccine

scientific article

Protective immunization against inhalational anthrax: a comparison of minimally invasive delivery platforms.

scientific article published on 15 December 2004

Rationally Attenuated Vaccines for Venezuelan Equine Encephalitis Protect Against Epidemic Strains with a Single Dose

scientific article published on 02 September 2020

Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus

scientific article published on August 2011

Recent advances in the development of vaccines against ricin

scientific article published on 25 January 2016

Rescue of rhesus macaques from the lethality of aerosolized ricin toxin

scientific article published on 10 January 2019

Reversion of Ebolavirus Disease from a Single Intramuscular Injection of a Pan-Ebolavirus Immunotherapeutic

scientific article published on 7 June 2022

Serial cultivation of normal human keratinocytes: a defined system for studying the regulation of growth and differentiation

scientific article published on June 1, 1992

Susceptibility of monkeypox virus aerosol suspensions in a rotating chamber.

scientific article published on 6 November 2012

Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndrome

scientific article

Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy.

scientific article

The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence

scientific article published on May 2015

The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

scientific article published on 16 June 2020

The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs.

scientific article published on 7 March 2012

The automated bioaerosol exposure system: preclinical platform development and a respiratory dosimetry application with nonhuman primates.

scientific article published in January 2004

Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection

scientific article

Wildfire Associated Health Risks Impacting Farmers and Ranchers

scientific article published on 26 February 2019

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