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List of works by Thierry Defrance

A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

scientific article published on 18 August 2015

A role for the VLA-4 integrin in the activation of human memory B cells

scientific article published in November 1997

Activation of human B lymphocytes through CD40 and interleukin 4

scientific article published on 01 August 1989

Activation sensitizes human memory B cells to B-cell receptor-induced apoptosis

scientific article published on September 1999

Am"B"valent: anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis.

scientific article published on 25 March 2010

Analysis of the B-cell growth-promoting activity of human IL-4, the co-stimulatory assay with anti-immunoglobulin antibodies. Comparison with the B-cell growth-promoting activity of other lymphokines

scientific article published on 01 June 1989

Antigen receptor-induced apoptosis of human germinal center B cells is targeted to a centrocytic subset

scientific article published in February 1997

Antiproliferative effects of interleukin-4 on freshly isolated non-Hodgkin malignant B-lymphoma cells

scientific article

B Cells Loaded with Synthetic Particulate Antigens: A Versatile Platform To Generate Antigen-Specific Helper T Cells for Cell Therapy.

scientific article

B cell growth-promoting activity of recombinant human interleukin 4

scientific article published on 01 August 1987

BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially

scientific article (publication date: 15 March 2002)

CD1d-restricted peripheral T cell lymphoma in mice and humans

scientific article published on 11 April 2016

CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression.

scientific article published on 19 February 2018

Cell therapy to induce allograft tolerance: time to switch to plan B?

scientific article

Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells

scientific article

Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis

scientific article

Death-receptor contribution to the germinal-center reaction.

scientific article

Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.

scientific article published on 20 November 2017

Expression and function of DRC-1 antigen

scientific article published on 01 January 1994

Expression of macrophage inflammatory protein-3alpha, stromal cell-derived factor-1, and B-cell-attracting chemokine-1 identifies the tonsil crypt as an attractive site for B cells

scientific article published on 01 June 2001

FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis

scientific article

Fas-dependent and Fas-independent mechanisms for selection of the mature human B cell repertoire.

scientific article published on April 1997

Growth factor requirements for the stimulation of germinal center B cells: evidence for an IL-2-dependent pathway of development

scientific article published on 01 December 1991

Highly Variable Sialylation Status of Donor-Specific Antibodies Does Not Impact Humoral Rejection Outcomes

scientific article published on 20 March 2019

Human interferon-gamma acts as a B cell growth factor in the anti-IgM antibody co-stimulatory assay but has no direct B cell differentiation activity.

scientific article published in December 1986

Human interleukin 4 down-regulates the surface expression of CD5 on normal and leukemic B cells

scientific article published on 01 February 1989

Human interleukin 4.

scientific article

Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM

scientific article published on 01 September 1988

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

scientific article published on June 1987

Human recombinant interleukin 4 induces normal B cells to produce soluble CD23/IgE-binding factor analogous to that spontaneously released by lymphoblastoid B cell lines

scientific article published on 01 January 1988

Identification of a tonsil IgD+ B cell subset with phenotypical and functional characteristics of germinal center B cells

scientific article published on 01 August 1996

In vitro Activation of B-CLL Cells

scientific article published on 01 January 1991

Interleukin (IL) 4 counteracts the helper effect of IL2 on antigen-activated human B cells

scientific article published on 01 April 1989

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

scientific article

Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

scientific article

Interleukin 13 is a B cell stimulating factor

scientific article

Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2.

scientific article published on October 1988

Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway.

scientific article published on 22 September 2003

Mature B cells: apoptosis checkpoints.

scientific article

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

scientific article (publication date: 7 December 2016)

Measles Virus Nucleocapsid Protein Binds to FcγRII and Inhibits Human B Cell Antibody Production ⬇️

scientific article published on July 21, 1997

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

scientific article published on 25 November 2019

Mitochondria connects the antigen receptor to effector caspases during B cell receptor-induced apoptosis in normal human B cells

scientific article published in November 1999

Moabs MAS516 and 5B5, two fibroblast markers, recognize human follicular dendritic cells

scientific article published on 01 September 1994

Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation.

scientific article published in November 1998

Modulation of B lymphocyte proliferation inside the germinal center

scientific article published on 01 January 1995

Mouse and Human Liver Contain Immunoglobulin A-Secreting Cells Originating From Peyer's Patches and Directed Against Intestinal Antigens

scientific article published on 27 April 2016

Phenotypic and functional heterogeneity of the IgD- B cell compartment: identification of two major tonsillar B cell subsets

scientific article published on 01 October 1993

Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo

scientific article published on 31 October 2015

Proliferation and differentiation of human CD5+ and CD5- B cell subsets activated through their antigen receptors or CD40 antigens

scientific article published on 01 November 1992

Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma

scientific article published on 01 April 1988

Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule

scientific article published on June 1995

Regulation of the Fas death pathway by FLICE-inhibitory protein in primary human B cells

scientific article published on 01 September 2000

Residual Activatability of Circulating Tfh17 Predicts Humoral Response to Thymodependent Antigens in Patients on Therapeutic Immunosuppression

scientific article published on 01 January 2018

Response of LFA-1-deficient B cells to interleukin 4 (BSF-1) and low molecular weight B cell growth factor (BCGFlow).

scientific article

Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors

scientific article published on December 1992

T cell-independent B cell memory

scientific article published on 07 April 2011

TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses

scientific article published on 01 June 2007

The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent.

scientific article published in March 1996

The endoplasmic reticulum is a key component of the plasma cell death pathway

scientific article

The influence of follicular dendritic cells on B-cell proliferation depends on the activation of B cells and the mitogen used

scientific article published on 01 January 1996

The origin of the plasma-cell heterogeneity.

scientific article published on 23 January 2015

The response of selected human B cell lines to B cell growth and differentiation factors.

scientific article published on April 1987

The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells

scientific article published on 18 September 2009

The vitronectin receptor (alpha v beta 3) is implicated, in cooperation with P-selectin and platelet-activating factor, in the adhesion of monocytes to activated endothelial cells

scientific article published on December 1994

Toll-like receptor agonists allow generation of long-lasting antipneumococcal humoral immunity in response to a plain polysaccharidic vaccine

scientific article published in August 2010

Towards identification of memory B cells in human tonsils.

scientific article published in January 1994

Transforming growth factor beta (TGF beta) directs IgA1 and IgA2 switching in human naive B cells

scientific article published on 01 January 1995

Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells.

scientific article published in August 1998

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