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List of works by Willem J.M. Mulder

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

scientific article

A fluorescent, paramagnetic and PEGylated gold/silica nanoparticle for MRI, CT and fluorescence imaging

scientific article published on July 2010

A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets

scientific article published in July 2004

A modular approach toward producing nanotherapeutics targeting the innate immune system

scientific article published in 2021

A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting

scientific article

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation

scientific article published on January 2014

A systematic comparison of clinically viable nanomedicines targeting HMG-CoA reductase in inflammatory atherosclerosis

scientific article published on 09 July 2017

A versatile and tunable coating strategy allows control of nanocrystal delivery to cell types in the liver

scientific article published on March 2011

An 89Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor

scientific article published on 16 August 2019

An ApoA-I mimetic peptide high-density-lipoprotein-based MRI contrast agent for atherosclerotic plaque composition detection

scientific article

An iterative sparse deconvolution method for simultaneous multicolor 19 F-MRI of multiple contrast agents

scientific article published on 23 August 2019

Anginex-conjugated liposomes for targeting of angiogenic endothelial cells

scientific article published on 23 March 2007

Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells.

scientific article published in July 2006

Annexin A5-functionalized bimodal lipid-based contrast agents for the detection of apoptosis

scientific article published in May 2006

Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques

scientific article

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

scientific article published on 29 August 2020

Applying nanomedicine in maladaptive inflammation and angiogenesis

scientific article published on 12 May 2017

Atherosclerosis Immunoimaging by Positron Emission Tomography

scientific article published on 06 February 2020

Atherosclerotic plaque composition: analysis with multicolor CT and targeted gold nanoparticles

scientific article

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging

scientific article

Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy

scientific article published on 13 April 2016

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

scientific article published on 01 August 2018

Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published in 2021

Cancer Immunotherapy: From local to global.

scientific article published in September 2017

Cardiovascular Immunotherapy and the Role of Imaging.

scientific article published in November 2017

Cellular compartmentalization of internalized paramagnetic liposomes strongly influences both T1and T2relaxivity

scientific article published on 01 May 2009

Collagen-specific peptide conjugated HDL nanoparticles as MRI contrast agent to evaluate compositional changes in atherosclerotic plaque regression.

scientific article published on 20 February 2013

Combination nanotherapy penetrates atherosclerosis

scientific article published on 17 December 2015

Comparison of synthetic high density lipoprotein (HDL) contrast agents for MR imaging of atherosclerosis

scientific article published on May 2009

Conformational Changes in High-Density Lipoprotein Nanoparticles Induced by High Payloads of Paramagnetic Lipids

scientific article published on 26 September 2016

Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque.

scientific article published on 29 September 2010

Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis

scientific article published on 01 December 2018

Defining trained immunity and its role in health and disease

scientific article published on 04 March 2020

Development and Multiparametric Evaluation of Experimental Atherosclerosis in Rabbits

scientific article published on 01 January 2018

Diagnostic and therapeutic strategies for small abdominal aortic aneurysms

scientific article published on 08 February 2011

Early in vivo assessment of angiostatic therapy efficacy by molecular MRI.

scientific article published on 3 January 2007

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

scientific article

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

scientific article published on 16 April 2018

Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging

scientific article published on 3 May 2012

Erratum: A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation

scientific article published in Nature Communications

Fluorescent nanoparticles for the accurate detection of drug delivery

scientific article published on 21 August 2015

Gold nanocrystal labeling allows low-density lipoprotein imaging from the subcellular to macroscopic level.

scientific article published on 17 October 2013

HDL as a contrast agent for medical imaging

scientific article

HDL mimetic CER-001 targets atherosclerotic plaques in patients

scientific article

HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages

scientific article published on 13 February 2015

High-Density Lipoprotein Nanobiologics for Precision Medicine.

scientific article published on 27 December 2017

High-density lipoprotein is a nanoparticle, but not all nanoparticles are high-density lipoprotein.

scientific article published on 31 July 2013

High-density lipoprotein-based contrast agents for multimodal imaging of atherosclerosis.

scientific article published on 08 October 2009

High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents

scientific article

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

scientific article

Hybrid PET- and MR-driven attenuation correction for enhanced 18F-NaF and 18F-FDG quantification in cardiovascular PET/MR imaging

scientific article published on 30 October 2019

Hybrid PET/MR Kernelised Expectation Maximisation Reconstruction for Improved Image-Derived Estimation of the Input Function from the Aorta of Rabbits

scientific article published on 16 January 2019

Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons

scientific article published on 10 November 2020

Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs

scientific article published on 20 October 2020

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis

scientific article

Imaging Tropoelastin in Atherosclerosis

scientific article published on 01 August 2018

Imaging and nanomedicine in inflammatory atherosclerosis

scientific article

Imaging and quantifying the morphology of an organic–inorganic nanoparticle at the sub-nanometre level

article

Imaging neuroinflammation after stroke: current status of cellular and molecular MRI strategies

scientific article

Imaging of angiogenesis

scientific article published on 01 June 2010

Imaging systemic inflammatory networks in ischemic heart disease

scientific article

Imaging the efficacy of anti-inflammatory liposomes in a rabbit model of atherosclerosis by non-invasive imaging

scientific article published on January 2012

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species

scientific article published on 01 August 2019

Imaging-guided revival of nanomedicine?

scientific article published on 23 November 2016

Immune cell screening of a nanoparticle library improves atherosclerosis therapy

scientific article

Improved biocompatibility and pharmacokinetics of silica nanoparticles by means of a lipid coating: a multimodality investigation

scientific article

Improved magnetic resonance molecular imaging of tumor angiogenesis by avidin-induced clearance of nonbound bimodal liposomes.

scientific article

In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging

scientific article published on December 2011

In vivo imaging of enhanced leukocyte accumulation in atherosclerotic lesions in humans

scientific article published on 01 September 2014

Incorporation of an apoE-derived lipopeptide in high-density lipoprotein MRI contrast agents for enhanced imaging of macrophages in atherosclerosis

scientific article

Influence of cell-internalization on relaxometric, optical and compositional properties of targeted paramagnetic quantum dot micelles

article

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance

scientific article published on 06 November 2018

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

scientific article

Inorganic nanocrystals as contrast agents in MRI: synthesis, coating and introduction of multifunctionality

scientific article

Integrating nanomedicine and imaging

scientific article published in November 2017

Investigating supramolecular systems using Förster resonance energy transfer

scientific article published on 01 September 2018

Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging

scientific article

In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.

scientific article published on 13 May 2016

Iron oxide core oil-in-water emulsions as a multifunctional nanoparticle platform for tumor targeting and imaging

scientific article published on 23 September 2009

Kinetics of avidin-induced clearance of biotinylated bimodal liposomes for improved MR molecular imaging

scientific article published in December 2008

Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging

scientific article

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.

scientific article

Liposome-enhanced MRI of neointimal lesions in the ApoE-KO mouse.

scientific article published in May 2006

MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle.

scientific article

MRI contrast agents: current status and future perspectives.

scientific article

MRI of ICAM-1 upregulation after stroke: the importance of choosing the appropriate target-specific particulate contrast agent

scientific article published on August 2013

Magnetic and fluorescent nanoparticles for multimodality imaging.

scientific article published on June 2007

Magnetic quantum dots for multimodal imaging

scientific article published on September 2009

Magnetic resonance imaging of vulnerable atherosclerotic plaques: current imaging strategies and molecular imaging probes

scientific article published on September 2007

Magnetic resonance molecular imaging contrast agents and their application in atherosclerosis.

scientific article published on October 2007

Magnetic resonance molecular imaging of thrombosis in an arachidonic acid mouse model using an activated platelet targeted probe.

scientific article

Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices

scientific article

Modified natural nanoparticles as contrast agents for medical imaging.

scientific article

Molecular imaging of macrophages in atherosclerotic plaques using bimodal PEG-micelles.

scientific article published in December 2007

Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots

scientific article

Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3)

scientific article published on 01 October 2018

Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.

scientific article

Morphology, binding behavior and MR-properties of paramagnetic collagen-binding liposomes

scientific article

Multifunctional gold nanoparticles for diagnosis and therapy of disease

scientific article

Multifunctional imaging nanoprobes

scientific article published on March 2010

Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

scientific article

Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall

scientific article published on 07 June 2019

Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis

scientific article

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis

scientific article published on 01 November 2020

Multimodality nanotracers for cardiovascular applications.

scientific article published on August 2008

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis

scientific article published on 17 October 2018

Nanoclusters of iron oxide: effect of core composition on structure, biocompatibility, and cell labeling efficacy

scientific article

Nanocrystal Core Lipoprotein Biomimetics for Imaging of Lipoproteins and Associated Diseases

scientific article published on February 2013

Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform

scientific article published on 22 October 2008

Nanoemulsion based delivery of fluorescent PARP inhibitors in mouse models of small cell lung cancer

scientific article published on 07 November 2018

Nanoimmunotherapy to treat ischaemic heart disease

scientific article published on 01 January 2019

Nanomedical Theranostics in Cardiovascular Disease.

scientific article published on 29 November 2011

Nanomedicine captures cardiovascular disease.

scientific article published in May 2008

Nanomedicines for Endothelial Disorders

scientific article published on December 2015

Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy

scientific article published on 10 July 2019

Nanoparticles as magnetic resonance imaging contrast agents for vascular and cardiac diseases

scientific article published on 21 October 2010

Nanoparticulate assemblies of amphiphiles and diagnostically active materials for multimodality imaging

scientific article published on July 2009

Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy.

scientific article published on 20 June 2016

Nanotechnology in medical imaging: probe design and applications.

scientific article published on 04 December 2008

Near-Infrared Quantum Dot and 89Zr Dual-Labeled Nanoparticles for in Vivo Cerenkov Imaging

scientific article

Near-infrared fluorescence energy transfer imaging of nanoparticle accumulation and dissociation kinetics in tumor-bearing mice

scientific article published on 24 October 2013

Neutrophil derived CSF1 induces macrophage polarization and promotes transplantation tolerance.

scientific article

Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.

scientific article

Nuclear imaging approaches facilitating nanomedicine translation

scientific article published on 25 July 2020

PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles

scientific article published on 25 June 2015

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis

scientific article published in January 2018

Paramagnetic and fluorescent liposomes for target-specific imaging and therapy of tumor angiogenesis.

scientific article published on June 2010

Paramagnetic lipid-coated silica nanoparticles with a fluorescent quantum dot core: a new contrast agent platform for multimodality imaging

scientific article

Periodicity in tumor vasculature targeting kinetics of ligand-functionalized nanoparticles studied by dynamic contrast enhanced magnetic resonance imaging and intravital microscopy

scientific article

Perspectives and opportunities for nanomedicine in the management of atherosclerosis.

scientific article

Pharmaceutical development and preclinical evaluation of a GMP-grade anti-inflammatory nanotherapy.

scientific article published on 17 March 2015

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

scientific article published on 16 January 2017

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration

scientific article

Preparation and stability of lipid-coated nanocapsules of cisplatin: anionic phospholipid specificity

scientific article published on May 2004

Probing lipid coating dynamics of quantum dot core micelles via Förster resonance energy transfer

scientific article published on 16 December 2013

Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging

scientific article published on 20 April 2020

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis.

scientific article published on 06 January 2014

Prosaposin mediates inflammation in atherosclerosis

scientific article published in 2021

Protein-liposome conjugates using cysteine-lipids and native chemical ligation.

scientific article

Quantum dot and Cy5.5 labeled nanoparticles to investigate lipoprotein biointeractions via Förster resonance energy transfer

scientific article published on 18 November 2010

Quantum dots for multimodal molecular imaging of angiogenesis.

scientific article published on 16 June 2010

Quantum dots with a paramagnetic coating as a bimodal molecular imaging probe

scientific article published in January 2006

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

scientific article published on 20 December 2017

RGD peptide functionalized and reconstituted high-density lipoprotein nanoparticles as a versatile and multimodal tumor targeting molecular imaging probe

scientific article

Radiolabeled antibodies in renal cell carcinoma

scientific article

Real-Time Monitoring of Nanoparticle Formation by FRET Imaging

scientific article published on 23 January 2017

Regulating trained immunity with nanomedicine

scientific article published in 2022

Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study.

scientific article published on 11 January 2017

Relaxivity of liposomal paramagnetic MRI contrast agents.

scientific article

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

scientific article published in 2023

Reversible Electroporation-Mediated Liposomal Doxorubicin Delivery to Tumors Can Be Monitored With 89Zr-Labeled Reporter Nanoparticles

scientific article published in January 2018

Science to Practice: Versatile Method to Track Transplanted Encapsulated Islet Cells with Multiple Imaging Modalities

scientific article published in January 2011

Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics.

scientific article

Smart cancer nanomedicine

scientific article published on 06 November 2019

Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer

scientific article published on 18 May 2018

Specific Binding of Liposomal Nanoparticles through Inverse Electron-Demand Diels-Alder Click Chemistry

scientific article published on 7 August 2017

Synergistic targeting of alphavbeta3 integrin and galectin-1 with heteromultivalent paramagnetic liposomes for combined MR imaging and treatment of angiogenesis

scientific article published on 01 January 2010

Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform

scientific article published on October 2013

Synthesis of polymer-lipid nanoparticles for image-guided delivery of dual modality therapy

scientific article published on 21 August 2013

Systems Biology and Noninvasive Imaging of Atherosclerosis.

scientific article published on February 2016

Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes

scientific article published on 9 June 2008

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

scientific article

Targeting Trained Innate Immunity With Nanobiologics to Treat Cardiovascular Disease

scientific article published in 2021

Targeting myeloperoxidase in inflammatory atherosclerosis

scientific article published on 01 September 2018

The biological properties of iron oxide core high-density lipoprotein in experimental atherosclerosis.

scientific article published on January 2011

The complex fate in plasma of gadolinium incorporated into high-density lipoproteins used for magnetic imaging of atherosclerotic plaques

scientific article published on 10 May 2013

The effect of nanoparticle polyethylene glycol surface density on ligand-directed tumor targeting studied in vivo by dual modality imaging.

scientific article

The evolution of MRI probes: from the initial development to state-of-the-art applications

article

Therapeutic targeting of trained immunity

scientific article published on 01 July 2019

Three-dimensional dynamic contrast-enhanced MRI for the accurate, extensive quantification of microvascular permeability in atherosclerotic plaques

scientific article published on 30 August 2015

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

scientific article published on 01 October 2020

Trained immunity in organ transplantation

scientific article published on 28 October 2019

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published on 08 December 2020

Trained immunity: adaptation within innate immune mechanisms

scientific article published in 2023

Tumor Targeting by αvβ3-Integrin Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking

scientific article published on 15 May 2020

Tumor angiogenesis phenotyping by nanoparticle-facilitated magnetic resonance and near-infrared fluorescence molecular imaging.

scientific article

Tyrosine polyethylene glycol (PEG)-micelle magnetic resonance contrast agent for the detection of lipid rich areas in atherosclerotic plaque

scientific article published on November 2009

Ultra-high resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T

scientific article published on 14 December 2020

Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging.

scientific article

Whole-Body Atherosclerosis Imaging by Positron Emission Tomography/Magnetic Resonance Imaging: From Mice to Nonhuman Primates

scientific article published on 02 April 2020

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