List of works - Shigenobu Shibata

2,2,2-Tribromoethanol phase-shifts the circadian rhythm of the liver clock in Per2::Luciferase knockin mice: lack of dependence on anesthetic activity

scientific article published on 13 December 2011

A balanced diet is necessary for proper entrainment signals of the mouse liver clock

scientific article

A low-protein diet eliminates the circadian rhythm of serum insulin and hepatic lipid metabolism in mice

scientific article published on 11 October 2018

A role of nociceptin in the entrainment mechanism of the biological clock

scientific article published in October 2005

A single daily meal at the beginning of the active or inactive period inhibits food deprivation-induced fatty liver in mice

scientific article published on 13 June 2014

Abnormal tuning of the hepatic circadian metabolic rhythms in lung cancer

scientific article published on 10 December 2016

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

scientific article

Adrenergic regulation of clock gene expression in mouse liver

scientific article

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.

scientific article published on 4 August 2017

Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation

scientific article

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice

scientific article published on 28 March 2005

Anatomical cross-sectional area of the quadriceps femoris and sit-to-stand test score in middle-aged and elderly population: development of a predictive equation

scientific article published on 29 June 2016

Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model

scientific article

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

scientific article

Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

scientific article published on 7 December 2016

Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice

scientific article (publication date: 9 March 2011)

Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet

scientific article published in August 2007

Basic and applied science of chrononutrition

scientific article published on March 2011

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1.

scientific article published on 11 July 2014

Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin

scientific article

Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver

scientific article

Chrono-biology, chrono-pharmacology, and chrono-nutrition

scientific article published on 27 February 2014

Chrono-nutrition and n-3 polyunsaturated fatty acid

scientific article published in January 2018

Circadian Clock mutation in dams disrupts nursing behavior and growth of pups

scientific article published on 26 January 2006

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice

scientific article

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.

scientific article published on 13 June 2018

Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.

scientific article

Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

scientific article published on 18 August 2017

Circadian regulation of allergic reactions by the mast cell clock in mice

scientific article

Circadian rhythms in the CNS and peripheral clock disorders: preface

scientific article published on 14 February 2007

Circadian rhythms in the CNS and peripheral clock disorders: the circadian clock and hyperlipidemia

scientific article published on 14 February 2007

Circadian rhythms of liver physiology and disease: experimental and clinical evidence

scientific article published on 24 February 2016

Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet

scientific article published on 30 October 2007

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

scientific article published on 2 March 2017

Combination of meal and exercise timing with a high-fat diet influences energy expenditure and obesity in mice.

scientific article published on 9 July 2014

Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice

scientific article

Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.

scientific article published in July 2014

Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.

scientific article published on 14 April 2010

Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse

scientific article

Dietary intake is associated with human chronotype as assessed by both morningness-eveningness score and preferred midpoint of sleep in young Japanese women

scientific article

Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation

scientific article published on 9 March 2016

Differential effect of lithium on the circadian oscillator in young and old hamsters

scientific article

Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism

scientific article published on 15 May 2012

Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice

scientific article published on 17 April 2014

Eating meals before wheel-running exercise attenuate high fat diet-driven obesity in mice under two meals per day schedule.

scientific article published on 2 June 2015

Effect of chronic ethanol exposure on the liver of Clock-mutant mice

scientific article published on April 2009

Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei

scientific article published in April 2004

Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus

scientific article published on 25 June 2014

Effects of Meal Timing on Postprandial Glucose Metabolism and Blood Metabolites in Healthy Adults

Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice

scientific article

Effects of medial hypothalamic lesions on feeding-induced entrainment of locomotor activity and liver Per2 expression in Per2::luc mice

scientific article published in February 2010

Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions

scientific article

Entrainment of the mouse circadian clock by sub-acute physical and psychological stress

scientific article published on 15 June 2015

Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition

scientific article published on 22 December 2017

Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis

scientific article

Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice

scientific article

Facilitation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents ⬇️

scientific article published on May 1, 2003

Feeding and adrenal entrainment stimuli are both necessary for normal circadian oscillation of peripheral clocks in mice housed under different photoperiods

scientific article published on 6 October 2014

Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120.

scientific article published on 10 July 2015

Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al.

scientific article published on 10 August 2009

Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2::LUC mice

scientific article published on 8 June 2016

Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet

scientific article published on 26 January 2018

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

scientific article published on 4 December 2007

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

scientific article published on 23 January 2018

Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice

scientific article published on 27 May 2015

Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise

scientific article

In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress

scientific article published on 26 April 2016

In vivo monitoring of peripheral circadian clocks in the mouse

scientific article

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock

scientific article published on 7 November 2015

Inhibitory action of 5-HT1A agonist MKC-242 on triazolam-induced phase advances in hamster circadian activity rhythms

scientific article published on 7 May 2005

Involvement of 5-HT₃ and 5-HT₄ receptors in the regulation of circadian clock gene expression in mouse small intestine.

scientific article published on 4 February 2014

Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock

scientific article published on 20 January 2012

Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress.

scientific article published on 26 December 2015

MAP kinase‐dependent induction of clock gene expression by α1‐adrenergic receptor activation ⬇️

scientific article published on May 8, 2003

Meal frequency patterns determine the phase of mouse peripheral circadian clocks

scientific article

Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice

scientific article

Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse

scientific article published in September 2002

Modulation of rat behaviour by using a rat-like robot

scientific article published on 4 October 2013

Motor discoordination in mutant mice lacking junctophilin type 3

scientific journal article

Multifactorial regulation of daily rhythms in expression of the metabolically responsive gene spot14 in the mouse liver

scientific article published in August 2007

Neural regulation of the hepatic circadian rhythm

scientific article published in September 2004

Night eating model shows time-specific depression-like behavior in the forced swimming test

scientific article published on 18 January 2018

Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats

scientific article published on September 2005

ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle

scientific article published on 28 December 2006

Optimization of dosing schedule of daily inhalant dexamethasone to minimize phase shifting of clock gene expression rhythm in the lungs of the asthma mouse model

scientific article published on 5 April 2007

PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders

scientific article published on 9 April 2007

PPARα is a potential therapeutic drug target of circadian rhythm sleep disorders

Phase shifts in circadian peripheral clocks caused by exercise are dependent on the feeding schedule in PER2::LUC mice

scientific article published on 28 April 2016

Phase-delay in the light-dark cycle impairs clock gene expression and levels of serotonin, norepinephrine, and their metabolites in the mouse hippocampus and amygdala

scientific article published on 11 August 2015

Phase-resetting response to (+)8-OH-DPAT, a serotonin 1A/7 receptor agonist, in the mouse in vivo

scientific article published in September 2004

Polyporus and Bupleuri radix effectively alter peripheral circadian clock phase acutely in male mice

scientific article published on 18 May 2017

Positive association between physical activity and PER3 expression in older adults

scientific article published on 03 January 2017

Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblasts

scientific article

Potent synchronization of peripheral circadian clocks by glucocorticoid injections in PER2::LUC-Clock/Clock mice

scientific article published on 13 July 2017

Prednisolone causes anxiety- and depression-like behaviors and altered expression of apoptotic genes in mice hippocampus

scientific article published on 30 October 2009

Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice

scientific article

Refeeding after fasting elicits insulin-dependent regulation of Per2 and Rev-erbα with shifts in the liver clock

scientific article published in June 2011

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress

scientific article published on 11 January 2017

Restricted feeding induces daily expression of clock genes and Pai-1 mRNA in the heart of Clock mutant mice

scientific article

Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood

scientific article published on 31 October 2009

Social jetlag and menstrual symptoms among female university students

scientific article published on 05 November 2018

Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice

scientific article published on 26 March 2009

Synthesis of a new [6]-gingerol analogue and its protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet

scientific article published on 26 August 2011

The Role of Circadian Rhythms in Muscular and Osseous Physiology and Their Regulation by Nutrition and Exercise

scientific article published on 14 February 2017

The adjustment and manipulation of biological rhythms by light, nutrition, and abused drugs

scientific article published on 23 June 2010

The circadian clock controls fluctuations of colonic cell proliferation during the light/dark cycle via feeding behavior in mice.

scientific article published on 16 September 2015

The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice.

scientific article

The mammalian circadian clock and its entrainment by stress and exercise

scientific article

The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women

scientific article published on 5 February 2011

The role of Clock in the plasticity of circadian entrainment

scientific article published in June 2004

The role of GABAergic neuron on NMDA- and SP-induced phase delays in the suprachiasmatic nucleus neuronal activity rhythm in vitro

scientific article published on 13 November 2009

Time of day and nutrients in feeding govern daily expression rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liver

scientific article

Time-dependent effect of glutamate on long-term potentiation in the suprachiasmatic nucleus of rats

scientific article published in October 2002

Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver

scientific article published in January 2010

Two distinct serotonin receptors co-mediate non-photic signals to the circadian clock

scientific article published on 29 November 2013

Two-peaked Synchronization in Day/Night Expression Rhythms of the Fibrinogen Gene Cluster in the Mouse Liver ⬇️

scientific article published on May 14, 2003

Warm water bath stimulates phase-shifts of the peripheral circadian clocks in PER2::LUCIFERASE mouse

scientific article

[Chrono-nutrition and chrono-exercise].

scientific article published in December 2013

l-Ornithine affects peripheral clock gene expression in mice

scientific article published on 5 October 2016

γ-oryzanol ameliorates the acute stress induced by behavioral anxiety testing in mice

scientific article published on 07 June 2018

List of works by Shigenobu Shibata

2,2,2-Tribromoethanol phase-shifts the circadian rhythm of the liver clock in Per2::Luciferase knockin mice: lack of dependence on anesthetic activity

A balanced diet is necessary for proper entrainment signals of the mouse liver clock

A low-protein diet eliminates the circadian rhythm of serum insulin and hepatic lipid metabolism in mice

A role of nociceptin in the entrainment mechanism of the biological clock

A single daily meal at the beginning of the active or inactive period inhibits food deprivation-induced fatty liver in mice

Abnormal tuning of the hepatic circadian metabolic rhythms in lung cancer

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

Adrenergic regulation of clock gene expression in mouse liver

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.

Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice

Anatomical cross-sectional area of the quadriceps femoris and sit-to-stand test score in middle-aged and elderly population: development of a predictive equation

Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice

Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet

Basic and applied science of chrononutrition

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1.

Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin

Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver

Chrono-biology, chrono-pharmacology, and chrono-nutrition

Chrono-nutrition and n-3 polyunsaturated fatty acid

Circadian Clock mutation in dams disrupts nursing behavior and growth of pups

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.

Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.

Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

Circadian regulation of allergic reactions by the mast cell clock in mice

Circadian rhythms in the CNS and peripheral clock disorders: preface

Circadian rhythms in the CNS and peripheral clock disorders: the circadian clock and hyperlipidemia

Circadian rhythms of liver physiology and disease: experimental and clinical evidence

Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

Combination of meal and exercise timing with a high-fat diet influences energy expenditure and obesity in mice.

Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice

Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.

Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.

Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse

Dietary intake is associated with human chronotype as assessed by both morningness-eveningness score and preferred midpoint of sleep in young Japanese women

Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation

Differential effect of lithium on the circadian oscillator in young and old hamsters

Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism

Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice

Eating meals before wheel-running exercise attenuate high fat diet-driven obesity in mice under two meals per day schedule.

Effect of chronic ethanol exposure on the liver of Clock-mutant mice

Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei

Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus

Effects of Meal Timing on Postprandial Glucose Metabolism and Blood Metabolites in Healthy Adults

Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice

Effects of medial hypothalamic lesions on feeding-induced entrainment of locomotor activity and liver Per2 expression in Per2::luc mice

Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions

Entrainment of the mouse circadian clock by sub-acute physical and psychological stress

Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition

Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis

Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice

Facilitation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents ⬇️

Feeding and adrenal entrainment stimuli are both necessary for normal circadian oscillation of peripheral clocks in mice housed under different photoperiods

Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120.

Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al.

Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2::LUC mice

Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice

Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise

In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress

In vivo monitoring of peripheral circadian clocks in the mouse

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock

Inhibitory action of 5-HT1A agonist MKC-242 on triazolam-induced phase advances in hamster circadian activity rhythms

Involvement of 5-HT₃ and 5-HT₄ receptors in the regulation of circadian clock gene expression in mouse small intestine.

Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock

Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress.

MAP kinase‐dependent induction of clock gene expression by α1‐adrenergic receptor activation ⬇️

Meal frequency patterns determine the phase of mouse peripheral circadian clocks

Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice

Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse

Modulation of rat behaviour by using a rat-like robot

Motor discoordination in mutant mice lacking junctophilin type 3