List of works - Michael Schumacher

3beta-Hydroxysteroid dehydrogenase/5-ene-4-ene isomerase mRNA expression in rat brain: effect of pseudopregnancy and traumatic brain injury

scientific article

A Comparison of Different Dosages of a Continuous Preperitoneal Infusion and Systemic Administration of Ropivacaine After Laparotomy in Rats ⬇️

scientific article published on May 19, 2011

A Role of Endogenous Progesterone in Stroke Cerebroprotection Revealed by the Neural-Specific Deletion of Its Intracellular Receptors.

scientific article published on 6 October 2017

Binding of [3H]cholecystokinin in the ventromedial hypothalamus modulated by an afferent brainstem projection but not by ovarian steroids ⬇️

scientific article published on November 8, 1991

Cellular basis for progesterone neuroprotection in the injured spinal cord.

scientific article

Cerebroprotection by progesterone following ischemic stroke: Multiple effects and role of the neural progesterone receptors

scientific article published on 19 July 2018

Changes in serum concentrations of steroids during embryonic and post-hatching development of male and female Japanese quail (Coturnix coturnix japonica) ⬇️

scientific article published on 01 July 1988

Changes in testosterone metabolism by the brain and cloacal gland during sexual maturation in the Japanese quail (Coturnix coturnix japonica) ⬇️

scientific article published on January 1, 1984

Control of cell survival and proliferation of postnatal PSA-NCAM(+) progenitors

scientific article published in February 2003

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

article

Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain.

scientific article

Differential effects of the 18-kDa translocator protein (TSPO) ligand etifoxine on steroidogenesis in rat brain, plasma and steroidogenic glands: Pharmacodynamic studies

scientific article published on 3 June 2017

Differential recruitment of p160 coactivators by glucocorticoid receptor between Schwann cells and astrocytes

scientific journal article

Downregulation of steroidogenic acute regulatory protein (StAR) gene expression by cyclic AMP in cultured Schwann cells.

scientific article

Early activation of transcription factor expression in Schwann cells by progesterone

scientific journal article

Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury

scientific journal article

Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis

scientific article published on 28 August 2014

Estrogen-regulated synaptogenesis in the hippocampus: Sexual dimorphism in vivo but not in vitro ⬇️

scientific article published on November 25, 2011

Expression and functional state of the corticosteroid receptors and 11 beta-hydroxysteroid dehydrogenase type 2 in Schwann cells

scientific journal article

Genomic and membrane actions of progesterone: implications for reproductive physiology and behavior

scientific article

Immunocytochemical evidence for a progesterone receptor in neurons and glial cells of the rat spinal cord

scientific journal article

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.

scientific article published in April 2003

Induction of Type 3 Iodothyronine Deiodinase by Nerve Injury in the Rat Peripheral Nervous System ⬇️

scientific article published on December 1, 2001

Interplay between LXR and Wnt/ -Catenin Signaling in the Negative Regulation of Peripheral Myelin Genes by Oxysterols ⬇️

scientific article published on June 29, 2011

Intranasal administration of progesterone: A potential efficient route of delivery for cerebroprotection after acute brain injuries

scientific article published on 06 June 2018

Light-dark differences in behavioral sensitivity to oxytocin ⬇️

scientific article published on June 1, 1991

Lithium enhances remyelination of peripheral nerves ⬇️

scientific article published on February 21, 2012

Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

scientific article

Nestorone<sup>®</sup> , a 19nor-progesterone derivative boosts remyelination in an animal model of demyelination

scientific article published on 24 December 2020

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies.

scientific article published on 8 November 2016

Neuroprotection by steroids after neurotrauma in organotypic spinal cord cultures: a key role for progesterone receptors and steroidal modulators of GABA(A) receptors

scientific article published on 28 March 2013

Neuroprotective Effects of Testosterone in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis

scientific article published on 07 January 2021

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

scientific article published in November 2002

Neurosteroids, with special reference to the effect of progesterone on myelination in peripheral nerves ⬇️

scientific article published on April 1, 1997

Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system

scientific article

Ontogeny of testosterone-inducible brain aromatose activity ⬇️

scientific article published on February 16, 1988

Progesterone Attenuates Several Hippocampal Abnormalities of the Wobbler Mouse ⬇️

scientific article published on March 1, 2013

Progesterone Protective Effects in Neurodegeneration and Neuroinflammation ⬇️

scientific article published on November 1, 2013

Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex

scientific article

Progesterone and the oligodendroglial lineage: Stage‐dependent biosynthesis and metabolism ⬇️

scientific article published on December 1, 2001

Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination

scientific article (publication date: 2000)

Progesterone as a neurosteroid: synthesis and actions in rat glial cells

scientific article

Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury

scientific article published on 17 June 2011

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in rats with acute spinal cord injury

scientific article

Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord

scientific article published in February 2006

Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons.

scientific article published on 17 October 2006

Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease.

scientific article published in December 2002

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration.

scientific article published on 24 March 2009

Progesterone neuroprotection: The background of clinical trial failure.

scientific article

Progesterone receptors: a key for neuroprotection in experimental stroke.

scientific article published on 25 May 2012

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease

scientific article published in October 2005

Progesterone: therapeutic opportunities for neuroprotection and myelin repair.

scientific article published on 18 June 2007

Promoter activity and gene structure of rabbit FKBP52.

scientific article published on August 2003

Protective effects of the neurosteroid allopregnanolone in a mouse model of spontaneous motoneuron degeneration

scientific article

Rapid membrane effects of steroid hormones: an emerging concept in neuroendocrinology ⬇️

scientific article published on September 1, 1990

Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat ⬇️

scientific article published on September 1, 1991

Sex differences in the regulation of oxytocin receptors by ovarian steroids in the ventromedial hypothalamus of the rat

scientific article published on March 1, 1992

Steroid Profiling in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis

scientific article published on 29 August 2016

Steroid Regulation and Sex Differences in [3H]Muscimol Binding in Hippocampus, Hypothalamus and Midbrain in Rats ⬇️

scientific article published on August 1, 1992

Steroid profiling in preeclamptic women: evidence for aromatase deficiency

scientific article published on August 5, 2010

Steroid receptors in various glial cell lines expression and functional studies

scientific article published on November 2002

Steroids in Stroke with Special Reference to Progesterone

article

The membrane-associated progesterone-binding protein 25-Dx is expressed in brain regions involved in water homeostasis and is up-regulated after traumatic brain injury.

scientific article

The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors.

scientific article published on 2 March 2006

Therapeutic effects of progesterone in animal models of neurological disorders.

scientific article

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

scientific article

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

scientific article published on December 2010

Type 2 deiodinase in the peripheral nervous system: induction in the sciatic nerve after injury ⬇️

scientific article published on January 1, 2001

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

scientific article

List of works by Michael Schumacher

3beta-Hydroxysteroid dehydrogenase/5-ene-4-ene isomerase mRNA expression in rat brain: effect of pseudopregnancy and traumatic brain injury

A Comparison of Different Dosages of a Continuous Preperitoneal Infusion and Systemic Administration of Ropivacaine After Laparotomy in Rats ⬇️

A Role of Endogenous Progesterone in Stroke Cerebroprotection Revealed by the Neural-Specific Deletion of Its Intracellular Receptors.

Binding of [3H]cholecystokinin in the ventromedial hypothalamus modulated by an afferent brainstem projection but not by ovarian steroids ⬇️

Cellular basis for progesterone neuroprotection in the injured spinal cord.

Cerebroprotection by progesterone following ischemic stroke: Multiple effects and role of the neural progesterone receptors

Changes in serum concentrations of steroids during embryonic and post-hatching development of male and female Japanese quail (Coturnix coturnix japonica) ⬇️

Changes in testosterone metabolism by the brain and cloacal gland during sexual maturation in the Japanese quail (Coturnix coturnix japonica) ⬇️

Control of cell survival and proliferation of postnatal PSA-NCAM(+) progenitors

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain.

Differential effects of the 18-kDa translocator protein (TSPO) ligand etifoxine on steroidogenesis in rat brain, plasma and steroidogenic glands: Pharmacodynamic studies

Differential recruitment of p160 coactivators by glucocorticoid receptor between Schwann cells and astrocytes

Downregulation of steroidogenic acute regulatory protein (StAR) gene expression by cyclic AMP in cultured Schwann cells.

Early activation of transcription factor expression in Schwann cells by progesterone

Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury

Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis

Estrogen-regulated synaptogenesis in the hippocampus: Sexual dimorphism in vivo but not in vitro ⬇️

Expression and functional state of the corticosteroid receptors and 11 beta-hydroxysteroid dehydrogenase type 2 in Schwann cells

Genomic and membrane actions of progesterone: implications for reproductive physiology and behavior

Immunocytochemical evidence for a progesterone receptor in neurons and glial cells of the rat spinal cord

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.

Induction of Type 3 Iodothyronine Deiodinase by Nerve Injury in the Rat Peripheral Nervous System ⬇️

Interplay between LXR and Wnt/ -Catenin Signaling in the Negative Regulation of Peripheral Myelin Genes by Oxysterols ⬇️

Intranasal administration of progesterone: A potential efficient route of delivery for cerebroprotection after acute brain injuries

Light-dark differences in behavioral sensitivity to oxytocin ⬇️

Lithium enhances remyelination of peripheral nerves ⬇️

Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

Nestorone<sup>®</sup> , a 19nor-progesterone derivative boosts remyelination in an animal model of demyelination

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies.

Neuroprotection by steroids after neurotrauma in organotypic spinal cord cultures: a key role for progesterone receptors and steroidal modulators of GABA(A) receptors

Neuroprotective Effects of Testosterone in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

Neurosteroids, with special reference to the effect of progesterone on myelination in peripheral nerves ⬇️

Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system

Ontogeny of testosterone-inducible brain aromatose activity ⬇️

Progesterone Attenuates Several Hippocampal Abnormalities of the Wobbler Mouse ⬇️

Progesterone Protective Effects in Neurodegeneration and Neuroinflammation ⬇️

Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex

Progesterone and the oligodendroglial lineage: Stage‐dependent biosynthesis and metabolism ⬇️

Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination

Progesterone as a neurosteroid: synthesis and actions in rat glial cells

Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in rats with acute spinal cord injury

Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord

Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons.

Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease.

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration.

Progesterone neuroprotection: The background of clinical trial failure.

Progesterone receptors: a key for neuroprotection in experimental stroke.

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease

Progesterone: therapeutic opportunities for neuroprotection and myelin repair.

Promoter activity and gene structure of rabbit FKBP52.

Protective effects of the neurosteroid allopregnanolone in a mouse model of spontaneous motoneuron degeneration

Rapid membrane effects of steroid hormones: an emerging concept in neuroendocrinology ⬇️

Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat ⬇️

Sex differences in the regulation of oxytocin receptors by ovarian steroids in the ventromedial hypothalamus of the rat

Steroid Profiling in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis

Steroid Regulation and Sex Differences in [3H]Muscimol Binding in Hippocampus, Hypothalamus and Midbrain in Rats ⬇️

Steroid profiling in preeclamptic women: evidence for aromatase deficiency

Steroid receptors in various glial cell lines expression and functional studies

Steroids in Stroke with Special Reference to Progesterone

The membrane-associated progesterone-binding protein 25-Dx is expressed in brain regions involved in water homeostasis and is up-regulated after traumatic brain injury.

The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors.

Therapeutic effects of progesterone in animal models of neurological disorders.

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Type 2 deiodinase in the peripheral nervous system: induction in the sciatic nerve after injury ⬇️

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?