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List of works by Karoly Toth

A fully replication-competent adenovirus vector with enhanced oncolytic properties

scientific article

A multitasking oncolytic adenovirus vector

article

Adenovirus immunoregulatory E3 proteins prolong transplants of human cells in immunocompetent mice.

scientific article published on March 2005

Adenovirus replication-competent vectors (KD1, KD3) complement the cytotoxicity and transgene expression from replication-defective vectors (Ad-GFP, Ad-Luc)

scientific article published on 01 August 2002

Adenovirus vectors for gene therapy, vaccination and cancer gene therapy

scientific article

Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters.

scientific article published on 8 July 2017

Characterization of an N-Terminal Non-Core Domain of RAG1 Gene Disrupted Syrian Hamster Model Generated by CRISPR Cas9.

scientific article

Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model

scientific article

Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.

scientific article

Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region

scientific article published on 01 September 2002

Cotton rat tumor model for the evaluation of oncolytic adenoviruses.

scientific article published on January 2005

Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters

scientific article

Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.

scientific article

Generation and characterization of an IL2RG knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients

scientific article published on 10 July 2020

HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.

scientific article

HEK? No!

scientific article

INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies.

scientific article

Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

scientific article

Immunosuppression enhances oncolytic adenovirus replication and antitumor efficacy in the Syrian hamster model.

scientific article

Increasing the Efficacy of Oncolytic Adenovirus Vectors

scientific article published on August 27, 2010

Male Syrian hamsters are more susceptible to intravenous infection with species C human adenoviruses than are females

scientific article published on 10 November 2017

New drug on the horizon for treating adenovirus

scientific article published on 2 September 2015

New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster.

scientific article

Oncolytic (replication-competent) adenoviruses as anticancer agents.

scientific article published on March 2010

Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus

article

Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model

scientific article

STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control

scientific article published on 20 August 2015

Specific recruitment of γδ regulatory T cells in human breast cancer.

scientific article published on 19 August 2013

Syrian Hamster Tumor Model to Study Oncolytic Ad5-Based Vectors

scientific article published on January 1, 2012

Syrian Hamster as an Animal Model to Study Oncolytic Adenoviruses and to Evaluate the Efficacy of Antiviral Compounds

scientific article published on January 1, 2012

Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors.

scientific article published on February 2006

The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors

scientific article published on 09 August 2013

Transcription factor TFIID is a direct functional target of the adenovirus E1A transcription-repression domain.

scientific article

Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters.

scientific article

Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

scientific article

Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters

scientific article

miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial–Mesenchymal Transition Signaling

scientific article published on March 8, 2012