List of works - Takehito Uruno

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

scientific article published on 31 July 2018

DOCK family proteins: key players in immune surveillance mechanisms

scientific article published on 01 January 2020

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation

scientific article published on 9 February 2018

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

scientific article

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

scientific article

DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

scientific article published on 27 December 2016

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

scientific article

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

scientific article

Distinct regulation of myoblast differentiation by intracellular and extracellular fibroblast growth factor-1

scientific article published on 01 January 1999

Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization

scientific article

Interaction of cortactin and Arp2/3 complex is required for sphingosine-1-phosphate-induced endothelial cell remodeling.

scientific article published in August 2004

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

scientific article

Molecular basis for barbed end uncapping by CARMIL homology domain 3 of mouse CARMIL-1

scientific article

Purification of capping protein using the capping protein binding site of CARMIL as an affinity matrix

scientific article published on 08 May 2009

S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches

scientific article published on 01 November 2019

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

scientific article

Selective role of neurokinin B in IL-31-induced itch response in mice

scientific article published on 09 August 2019

Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation

scientific article

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

scientific article

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

scientific article

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production.

scientific article published on 16 February 2018

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

scientific article

Thymic epithelial cell-specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes.

scientific article published on 22 May 2017

List of works by Takehito Uruno

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

DOCK family proteins: key players in immune surveillance mechanisms

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

Distinct regulation of myoblast differentiation by intracellular and extracellular fibroblast growth factor-1

Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization

Interaction of cortactin and Arp2/3 complex is required for sphingosine-1-phosphate-induced endothelial cell remodeling.

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

Molecular basis for barbed end uncapping by CARMIL homology domain 3 of mouse CARMIL-1

Purification of capping protein using the capping protein binding site of CARMIL as an affinity matrix

S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

Selective role of neurokinin B in IL-31-induced itch response in mice

Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production.

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

Thymic epithelial cell-specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes.