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List of works by Rui-Hua Xu

A Coiled-Coil Domain Containing 50 Splice Variant Is Modulated by Serine/Arginine-Rich Splicing Factor 3 and Promotes Hepatocellular Carcinoma in Mice by the Ras Signaling Pathway

scientific article published on 22 December 2018

A New Role for PHD in Chemotherapy ⬇️

scientific article published on August 14, 2012

A circRNA signature predicts postoperative recurrence in stage II/III colon cancer

scientific article published on 02 September 2019

A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio.

scientific article published on 2 May 2015

A pilot study of oxaliplatin, fluorouracil and folinic acid (FOLFOX-6) as first-line chemotherapy in advanced or recurrent gastric cancer.

scientific article published on 18 June 2008

A plasma cytokine and angiogenic factor (CAF) analysis for selection of bevacizumab therapy in patients with metastatic colorectal cancer

scientific article

A relationship between ABO blood groups and clinicopathologic characteristics of patients with gastric adenocarcinoma in China

scientific article published on 04 November 2010

A two-microRNA-based signature predicts first-line chemotherapy outcomes in advanced colorectal cancer patients

scientific article published on 18 December 2018

ABO blood group, hepatitis B viral infection and risk of pancreatic cancer.

scientific article published on 30 November 2011

AMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation

scientific article published on 17 September 2019

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

scientific article published on 14 January 2019

ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2.

scientific article

Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer

scientific article

Adjuvant chemotherapy, p53, carcinoembryonic antigen expression and prognosis after D2 gastrectomy for gastric adenocarcinoma.

scientific article published on January 2014

Alteration in TET1 as potential biomarker for immune checkpoint blockade in multiple cancers

scientific article published on 17 October 2019

Applying chemical bile duct embolization to achieve chemical hepatectomy in hepatolithiasis: a further experimental study

scientific article

Appraisal of Prognostic Interaction between Sidedness and Mucinous Histology in Colon Cancer: A Population-Based Study Using Inverse Probability Propensity Score Weighting

scientific article published on 01 January 2019

Are Risk Factors Associated with Outcomes in Pancreatic Cancer? ⬇️

scientific article published on July 24, 2012

Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer

scientific article published on November 2011

CBX4 Suppresses Metastasis via Recruitment of HDAC3 to the Runx2 Promoter in Colorectal Carcinoma.

scientific article

CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer

scientific article published on 10 June 2013

CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis

scientific article published on 11 July 2018

Carcinoembryonic antigen surge in metastatic colorectal cancer patients responding to irinotecan combination chemotherapy.

scientific article published in May 2010

Chemotherapy plus bevacizumab versus chemotherapy plus cetuximab as first-line treatment for patients with metastatic colorectal cancer: Results of a registry-based cohort analysis.

scientific article published on December 2016

Circular RNA: metabolism, functions and interactions with proteins

scientific article published on 14 December 2020

Circulating Liver Function Markers and Colorectal Cancer Risk: A Prospective Cohort Study in the UK Biobank

scientific article published on 22 October 2020

Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer

scientific article published on 01 January 2020

Classification of gastric cancer by EBV status combined with molecular profiling predicts patient prognosis

scientific article published on 01 January 2020

Clinical and prognostic analysis of hepatitis B virus infection in diffuse large B-cell lymphoma.

scientific article

Clinical characterization and prognostic factors of primary lymphoma of bone in case of Chinese patients

scientific article published on 31 August 2010

Clinical outcomes of Chinese patients with metastatic colorectal cancer receiving first-line bevacizumab-containing treatment.

scientific article published on 13 January 2015

Clinicopathologic and prognostic relevance of ARID1A protein loss in colorectal cancer

scientific article

Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China.

scientific article

Clinicopathological characteristics and prognostic analysis of gastric cancer in the young adult in China.

scientific article published on 23 December 2010

Comparison of 6th and 7th AJCC TNM staging classification for carcinoma of the stomach in China

scientific article published on 19 January 2011

Comparison of HER2 and Lauren Classification between Biopsy and Surgical Resection Samples, Primary and Metastatic Samples of Gastric Cancer

scientific article published on 30 September 2017

Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients

scientific article

Comparison of prognostic nomograms based on different nodal staging systems in patients with resected gastric cancer.

scientific article

Comparison of survival between right-sided and left-sided colon cancer in different situations.

scientific article published on 13 March 2018

Comparison of the prognostic value of various preoperative inflammation-based factors in patients with stage III gastric cancer

scientific article published on 24 December 2011

Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer

scientific article published on 05 April 2012

Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC).

scientific article published on 3 February 2012

Correlation between immune signature and high-density lipoprotein cholesterol level in stage II/III colorectal cancer

scientific article published on 07 February 2019

DNA methylation markers for diagnosis and prognosis of common cancers.

scientific article

DNA polymerase η protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy

scientific article

Defeating cancer: the 150 most important questions in cancer research and clinical oncology.

scientific article published on 28 December 2016

Designing gene panels for tumor mutational burden estimation: the need to shift from 'correlation' to 'accuracy'

scientific article published on 06 August 2019

Detailed analysis of prognostic factors in primary esophageal small cell carcinoma

scientific article published on 14 April 2014

Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma

scientific article

Development and Validation of a Nomogram to Predict the Benefit of Adjuvant Radiotherapy for Patients with Resected Gastric Cancer.

scientific article published on 29 September 2017

EGFR fluorescence in situ hybridization pattern of chromosome 7 disomy predicts resistance to cetuximab in KRAS wild-type metastatic colorectal cancer patients

scientific article

Editorial announcement regarding title change of Chinese Journal of Cancer to Cancer Communications

scientific article published on 09 March 2018

Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer.

scientific article published on 28 July 2015

Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy ⬇️

scientific article published on January 1, 2013

Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial

scientific article

Efficacy and safety of capecitabine as maintenance treatment after first-line chemotherapy using oxaliplatin and capecitabine in advanced gastric adenocarcinoma patients: a prospective observation

scientific article published on 11 February 2014

Efficacy and safety of cisplatin-based versus nedaplatin-based regimens for the treatment of metastatic/recurrent and advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis.

scientific article published on 21 November 2016

Elevated CA19-9 as the Most Significant Prognostic Factor in Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy

scientific article

Elevated baseline serum lactate dehydrogenase indicates a poor prognosis in primary duodenum adenocarcinoma patients.

scientific article published in January 2018

Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer

scientific article published in 2021

Eukaryotic Initiation Factor 5A2 Contributes to the Maintenance of CD133(+) Hepatocellular Carcinoma Cells via the c-Myc/microRNA-29b Axis

scientific article published on 9 November 2017

Expert opinions on immunotherapy for patients with colorectal cancer

scientific article published on 18 September 2020

Expressions of hypoxia-inducible factor-1α and hexokinase-II in gastric adenocarcinoma: the impact on prognosis and correlation to clinicopathologic features.

scientific article published on 16 September 2010

Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial.

scientific article published on 22 December 2017

FcγRIIA and IIIA polymorphisms predict clinical outcome of trastuzumab-treated metastatic gastric cancer.

scientific article published on 19 October 2017

Fibrinogen promotes malignant biological tumor behavior involving epithelial-mesenchymal transition via the p-AKT/p-mTOR pathway in esophageal squamous cell carcinoma

scientific article published on 11 August 2017

Frequency and clinicopathological features of metastasis to liver, lung, bone, and brain from gastric cancer: A SEER-based study

scientific article published on 09 July 2018

Genome sequencing analysis identifies Epstein–Barr virus subtypes associated with high risk of nasopharyngeal carcinoma

scientific article published on 17 June 2019

HBV infection decreases risk of liver metastasis in patients with colorectal cancer: A cohort study ⬇️

scientific article published on February 14, 2011

HER2-positive patients receiving trastuzumab treatment have a comparable prognosis with HER2-negative advanced gastric cancer patients: a prospective cohort observation.

scientific article published on 8 November 2013

Healing time of incision infection after hepatobiliary surgery treated by needle-free incision suture closure

scientific article

Hepatitis B virus infection is associated with younger median age at diagnosis and death in cancers.

scientific article published on April 2017

High hepatitis B virus infection in B-cell lymphoma tissue and its potential clinical relevance.

scientific article published in May 2012

Hypermethylation of APC2 Is a Predictive Epigenetic Biomarker for Chinese Colorectal Cancer

scientific article published on 29 October 2018

Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2.

scientific article

Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression.

scientific article

Impact of body mass index on survival of esophageal squamous carcinoma patients in southern China.

scientific article

Impact of pretreatment hematologic profile on survival of colorectal cancer patients.

scientific article published on 25 March 2010

Impact ofKRASmutation and PTEN expression on cetuximab-treated colorectal cancer ⬇️

scientific article published on December 14, 2010

Incidence of anemia, leukocytosis, and thrombocytosis in patients with solid tumors in China.

scientific article published on 23 July 2010

Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer

scientific article published on 29 September 2018

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer

scientific article published on 02 December 2019

Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming

scientific article published on 20 March 2020

Long noncoding RNA XIST expedites metastasis and modulates epithelial-mesenchymal transition in colorectal cancer.

scientific article published on 24 August 2017

Low preoperative albumin-globulin score predicts favorable survival in esophageal squamous cell carcinoma.

scientific article published on 20 April 2016

Lymph node staging systems in patients with gastric cancer treated with D2 resection plus adjuvant chemotherapy.

scientific article published on 6 January 2018

ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis

scientific article published in April 2018

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

scientific article published on 24 June 2019

MUC4, MUC16, and TTN genes mutation correlated with prognosis, and predicted tumor mutation burden and immunotherapy efficacy in gastric cancer and pan-cancer

scientific article published on 01 August 2020

Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway

scientific article published on 27 October 2016

Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-κB activation.

scientific article published on 7 October 2015

Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism

scientific article

Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential

scientific article

Modified XELIRI (capecitabine plus irinotecan) versus FOLFIRI (leucovorin, fluorouracil, and irinotecan), both either with or without bevacizumab, as second-line therapy for metastatic colorectal cancer (AXEPT): a multicentre, open-label, randomised

scientific article published on 16 March 2018

Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.

scientific article

Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma

scientific article published on 24 February 2017

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response.

scientific article published on April 2016

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

scientific article published on 16 October 2019

NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications

scientific article published on 07 October 2020

Nutrition support can bring survival benefit to high nutrition risk gastric cancer patients who received chemotherapy

scientific article published on 11 December 2014

Outcomes of preoperative chemoradiotherapy followed by surgery in patients with unresectable locally advanced sigmoid colon cancer.

scientific article published on 07 July 2016

Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Propyl Ester ⬇️

scientific article published on February 18, 2012

Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor ⬇️

scientific article published on 06 June 2012

Overexpression of SGLT1 and EGFR in colorectal cancer showing a correlation with the prognosis

scientific article published on 17 November 2010

Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer

scientific article

Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer

scientific article

PIWI-interacting RNA-54265 is oncogenic and a potential therapeutic target in colorectal adenocarcinoma.

scientific article published on 6 October 2018

POLE/POLD1 mutation in non‐exonuclease domain matters for predicting efficacy of immune‐checkpoint‐inhibitor therapy

scientific article published in 2021

Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer

scientific article

Pathologic response after preoperative therapy predicts prognosis of Chinese colorectal cancer patients with liver metastases.

scientific article published on 2 October 2017

Pathological Assessment of the AJCC Tumor Regression Grading System After Preoperative Chemoradiotherapy for Chinese Locally Advanced Rectal Cancer

scientific article published on January 2016

Patients with old age or proximal tumors benefit from metabolic syndrome in early stage gastric cancer.

scientific article

Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation.

scientific article published on 2 February 2018

Phase 2 study of capecitabine and irinotecan combination chemotherapy (modified XELIRI regimen) in patients with advanced gastric cancer.

scientific article published on December 2011

Phase I study of high-dose ascorbic acid with mFOLFOX6 or FOLFIRI in patients with metastatic colorectal cancer or gastric cancer

scientific article published on 16 May 2019

Phase II Study of Biweekly Paclitaxel Plus Infusional 5-Fluorouracil and Leucovorin as First-Line Chemotherapy in Patients With Advanced Gastric Cancer ⬇️

scientific article published on 01 August 2011

Phase II clinical trial of S-1 plus nanoparticle albumin-bound paclitaxel in untreated patients with metastatic gastric cancer

scientific article published on 26 October 2018

Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway

scientific article

Phase II trial of XELOX as first-line treatment for patients with advanced gastric cancer.

scientific article published on 30 March 2010

Phase III randomized, placebo-controlled, double-blind study of monosialotetrahexosylganglioside for the prevention of oxaliplatin-induced peripheral neurotoxicity in stage II/III colorectal cancer

scientific article published on 13 November 2019

Predictive and prognostic biomarkers with therapeutic targets in advanced colorectal cancer.

scientific article published on April 2014

Predictive value of chemotherapy-related high-density lipoprotein cholesterol (HDL) elevation in patients with colorectal cancer receiving adjuvant chemotherapy: an exploratory analysis of 851 cases.

scientific article published on 17 June 2016

Primary small cell carcinoma of the esophagus: clinicopathological study of 44 cases

scientific article

Prognostic analysis in node-negative gastric cancer patients in China

scientific article published on 22 December 2010

Prognostic effect of high pretreatment neutrophil to lymphocyte ratio on survival of patients with gastric adenocarcinoma in China.

scientific article published on January 2015

Prognostic effects of 25-hydroxyvitamin D levels in gastric cancer ⬇️

scientific article published on January 27, 2012

Prognostic factors and survival in patients with neuroendocrine tumors of the pancreas.

scientific article published on 9 April 2011

Prognostic relevance of BRD7 expression in colorectal carcinoma.

scientific article

Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma ⬇️

scientific article published on August 31, 2012

Prognostic significance and therapeutic implications of peroxisome proliferator-activated receptor γ overexpression in human pancreatic carcinoma.

scientific article published on 17 October 2014

Prognostic value of preoperative serum lactate dehydrogenase levels for resectable gastric cancer and prognostic nomograms

scientific article published on 19 May 2016

Proposal for a New TNM Stage based on the 7 and 8 American Joint Committee on Cancer pTNM Staging Classification for Gastric Cancer

scientific article published on 08 September 2018

Ratio of metastatic to resected lymph nodes enhances to predict survival in patients with stage III colorectal cancer.

scientific article published on 5 January 2011

Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications

scientific article published on 23 May 2016

Reduced expression of p21-activated protein kinase 1 correlates with poor histological differentiation in pancreatic cancer.

scientific article

Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.

scientific article published on 24 May 2016

Relationship of HER2 Alteration and Microsatellite Instability Status in Colorectal Adenocarcinoma

scientific article published on 04 May 2021

Right-sided colon cancer and left-sided colorectal cancers respond differently to cetuximab

scientific article

Role of capecitabine in treating metastatic colorectal cancer in Chinese patients.

scientific article published on 02 April 2014

S-1-based chemotherapy versus capecitabine-based chemotherapy as first-line treatment for advanced gastric carcinoma: a meta-analysis.

scientific article

SPP1 rs4754 and its epistatic interactions with SPARC polymorphisms in gastric cancer susceptibility.

scientific article published on 26 September 2017

Salvage gemcitabine-vinorelbine chemotherapy in patients with metastatic nasopharyngeal carcinoma pretreated with platinum-based chemotherapy.

scientific article

Serum HER 2 extracellular domain level is correlated with tissue HER 2 status in metastatic gastric or gastro-oesophageal junction adenocarcinoma

scientific article

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.

scientific article published on 21 March 2018

Suppression of fumarate hydratase activity increases the efficacy of cisplatin-mediated chemotherapy in gastric cancer

scientific article published on 28 May 2019

The Clinical and Biomarker Association of Programmed Death Ligand 1 and its Spatial Heterogeneous Expression in Colorectal Cancer

scientific article published on 21 October 2018

The Efficacy of Adjuvant FOLFOX6 for Patients With Gastric Cancer after D2 Lymphadenectomy: A Propensity Score-matched Analysis

scientific article published on April 2016

The Immunoscore system predicts prognosis after liver metastasectomy in colorectal cancer liver metastases

scientific article

The Impact of Glucocorticoids for Cirrhosis Patients Performed Major Liver Resection: A Retrospective Control Study

scientific article published on June 1, 2012

The Predictive Value of Albumin-to-Alkaline Phosphatase Ratio for Overall Survival of Hepatocellular Carcinoma Patients Treated with Trans-Catheter Arterial Chemoembolization Therapy

scientific article published on 08 September 2018

The Role of Adjuvant Chemotherapy for Colorectal Liver Metastasectomy after Pre-Operative Chemotherapy: Is the Treatment Worthwhile?

scientific article

The clinicopathologic relevance and prognostic value of tumor deposits and the applicability of N1c category in rectal cancer with preoperative radiotherapy

scientific article published on 16 September 2016

The effect of ventricular fibrillation time and NYHA classification on defibrillation in intensive care unit patients

scientific article published in February 2013

The effectiveness of lamivudine in preventing hepatitis B viral reactivation in rituximab-containing regimen for lymphoma.

scientific article

The extramural metastasis might be categorized in lymph node staging for colorectal cancer.

scientific article

The genomic landscape of small cell carcinoma of the esophagus.

scientific article

The predictive value of alkaline phosphatase and lactate dehydrogenase for overall survival in patients with esophageal squamous cell carcinoma

scientific article published on September 2015

The prognostic impact of preoperative blood monocyte count in pathological T3N0M0 rectal cancer without neoadjuvant chemoradiotherapy

scientific article

The progress of targeted therapy in advanced gastric cancer

scientific article published on 11 December 2013

The role of non-curative surgery in incurable, asymptomatic advanced gastric cancer

scientific article

The status of HBV infection influences metastatic pattern and survival in Chinese patients with pancreatic cancer

scientific article published on 08 October 2013

The survival benefit of palliative gastrectomy and/or metastasectomy in gastric cancer patients with synchronous metastasis: a population-based study using propensity score matching and coarsened exact matching

scientific article published on 01 January 2019

The tumor-log odds of positive lymph nodes-metastasis staging system, a promising new staging system for gastric cancer after D2 resection in China

scientific article

Tumor deposits: markers of poor prognosis in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy

scientific article published on 18 December 2015

Universal screening for Lynch syndrome in a large consecutive cohort of Chinese colorectal cancer patients: High prevalence and unique molecular features

scientific article published on 09 January 2019

VDR-SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment

scientific article published on 09 September 2020

Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism

scientific article

YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis

scientific article published on 27 January 2017

microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer.

scientific article published on May 2015

qPhos: a database of protein phosphorylation dynamics in humans

scientific article published on 01 January 2019

β-phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype

scientific article published on 05 December 2012

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