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List of works by Juliane Lokau

A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor

scientific article (publication date: 6 June 2014)

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

scientific article published on 22 February 2018

Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling

scientific article published on 13 May 2019

Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation

scientific article

Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.

scientific article published on 6 May 2016

Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.

scientific article

Enhancing Interleukin-6 and Interleukin-11 receptor cleavage.

scientific article

Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation

scientific article

Joint Reconstituted Signaling of the IL-6 Receptor via Extracellular Vesicles

scientific article published on 24 May 2020

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

scientific article published on 27 November 2019

Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling

scientific article published on 09 March 2017

Mutations in Craniosynostosis Patients Cause Defective Interleukin-11 Receptor Maturation and Drive Craniosynostosis-like Disease in Mice

scientific article published on 01 October 2018

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

scientific article published on 10 February 2016

Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation

scientific article

Proteolytic control of Interleukin-11 and Interleukin-6 biology

scientific article

Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35

scientific article

The SNP rs4252548 (R112H) which is associated with reduced human height compromises the stability of IL-11.

scientific article published on 10 December 2017

The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases

scientific article

The length of the interleukin-11 receptor stalk determines its capacity for classic signaling

scientific article published on 9 March 2018

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II

scientific article published on 21 March 2012

Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage

scientific article published on 14 December 2018

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