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List of works by Joseph L Witztum

'LDL-C' = LDL-C + Lp(a)-C: implications of achieved ultra-low LDL-C levels in the proprotein convertase subtilisin/kexin type 9 era of potent LDL-C lowering

scientific article published on June 2015

4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E‐null mice ⬇️

scientific article published on September 27, 2010

846 TIME RESTRICTED FEEDING PROTECTS AGAINST ATHEROSCLEROSIS BY MODULATING LUMINAL GUT MICROBIOME RHYTHMS

scientific article published in 2021

A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice

scientific article published on 29 September 2020

A comprehensive classification system for lipids

scientific article

A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome

scientific article published on 25 January 2007

A method for localizing the early products of nonenzymatic glycosylation in fixed tissue

scientific article published on 01 September 1989

A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma

scientific article published on 18 December 2018

A natural antibody to oxidized cardiolipin binds to oxidized low-density lipoprotein, apoptotic cells, and atherosclerotic lesions

scientific article published on 22 June 2006

A new category inJLR: Patient-Oriented Research Articles

scientific article published in 2006

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

scientific article

A novel mechanism by which probucol lowers low density lipoprotein levels demonstrated in the LDL receptor-deficient rabbit

scientific article published on 01 November 1984

A novel method for generating region-specific monoclonal antibodies to modified proteins. Application to the identification of human glucosylated low density lipoproteins

scientific article published on October 1983

ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis

scientific article

ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis.

scientific article

Abnormal Iron Deposition Associated With Lipid Peroxidation in Transgenic Mice Expressing Interleukin-6 in the Brain ⬇️

scientific article published on March 1, 1998

Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice

scientific article

Abundant expression of apoprotein E by macrophages in human and rabbit atherosclerotic lesions.

scientific article published in September 1993

Actin Polymerization in Macrophages in Response to Oxidized LDL and Apoptotic Cells: Role of 12/15-Lipoxygenase and Phosphoinositide 3-Kinase ⬇️

scientific article published on July 11, 2003

Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia

scientific article published on 24 May 2012

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

scientific article

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up

scientific article published in September 2017

Alterations in plasma vitamin E distribution in type 2 diabetic patients with elevated plasma phospholipid transfer protein activity

scientific article published in October 2004

Altered apolipoprotein B metabolism in very low density lipoprotein from lovastatin-treated guinea pigs.

scientific article

Aminoguanidine has both pro-oxidant and antioxidant activity toward LDL.

scientific article

Aminoguanidine inhibits oxidative modification of low density lipoprotein protein and the subsequent increase in uptake by macrophage scavenger receptors ⬇️

scientific article published on August 1, 1992

An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

scientific article published on 01 February 2020

An animal model to study local oxidation of LDL and its biological effects in the arterial wall

scientific article published in June 1998

Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein

scientific article

Antioxidant vitamin supplements and cardiovascular disease

scientific article published in August 2004

Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial

scientific article published on 11 August 2003

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein

scientific article published on August 1996

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

scientific article published in July 2015

Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice

scientific article published on 28 July 2008

Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice

scientific article published in April 2011

Antisense oligonucleotides for the treatment of dyslipidaemia ⬇️

scientific article published on May 24, 2012

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

scientific article published on 21 September 2016

Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study

scientific article published on 22 July 2015

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

scientific article published in May 1990

ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance

scientific article published on 14 May 2019

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.

scientific article published on 11 July 2016

ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis

scientific article published on 13 February 2020

ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.

scientific article published on 26 January 2007

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

scientific article published in April 1994

Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia.

scientific article published on 4 June 2015

Apolipoprotein B allotypes MB19(1) and MB19(2) in subjects with coronary artery disease and hypercholesterolemia

scientific article published on 01 January 1987

Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study

scientific article published on 4 May 2017

Apolipoprotein Profiles in Very Preterm and Term-Born Preschool Children

scientific article published on 01 April 2019

Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis

scientific article

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

scientific article

Are immunological mechanisms relevant for the development of atherosclerosis?

scientific article published on 01 February 1999

Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus

scientific article

Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation

scientific article published on 12 March 2020

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress

scientific article

Atheroprotective Vaccination with MHC-II Restricted Peptides from ApoB-100.

scientific article published on 27 December 2013

Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine

scientific article

Atherosclerosis. the road ahead

scientific article (publication date: 23 February 2001)

Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial

scientific article published on 9 March 2017

Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice

scientific article

Autoantibodies to oxidized LDL and cardiovascular risk: the Framingham Offspring Study

scientific article published on 14 February 2006

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

scientific article published in The Lancet

B cells and humoral immunity in atherosclerosis

scientific article

B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis

scientific article published in 2022

B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis

scientific article

B-Cell Aortic Homing and Atheroprotection Depend on Id3 ⬇️

scientific article published on October 27, 2011

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

scientific article (publication date: 6 April 1989)

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

scientific article

Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 28 January 2016

C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids

scientific article

C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathw

scientific article published in February 2007

CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Ldlr-/- Mice

scientific article published on 03 July 2020

CEP Is an Important and Ubiquitous Oxidation Specific Epitope Recognized by Innate Pattern Recognition Receptors

scientific article

CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice

scientific article published on 02 December 2018

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

scientific article published on 24 May 2017

Changes in dietary fat intake alter plasma levels of oxidized low-density lipoprotein and lipoprotein(a).

scientific article

Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet

scientific article

Characterization of an abnormal species of apolipoprotein B, apolipoprotein B-37, associated with familial hypobetalipoproteinemia

scientific article

Characterizing familial chylomicronemia syndrome: Baseline data of the APPROACH study

scientific article published on 31 May 2018

Cholesterol Accumulation in CD11c+ Immune Cells Is a Causal and Targetable Factor in Autoimmune Disease

scientific article

Cholesterol awareness--key to preventing coronary artery disease

scientific article

Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein

scientific article published on 8 February 2008

Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig.

scientific article published in January 1985

Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice

scientific article

Circulating autoantibodies to oxidized LDL correlate with impaired coronary endothelial function after cardiac transplantation

scientific article published in December 2002

Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2alpha)-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation by vitamin E.

scientific article

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

scientific article

Circulating oxidized low-density lipoprotein is increased in hypertension

scientific article published on 01 November 2003

Clinical and biochemical features of different molecular etiologies of familial chylomicronemia

scientific article

Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma

scientific article published on August 1996

Colestipol-induced changes in LDL composition and metabolism. II. Studies in humans

scientific article

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions ⬇️

scientific article published on September 1, 1990

Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

scientific article published on June 2000

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

scientific article published on 5 October 2011

Conservation of the low density lipoprotein receptor-binding domain of apoprotein B. Demonstration by a new monoclonal antibody, MB47

scientific article published on 01 March 1986

Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis

scientific article published on 20 April 2009

Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation

scientific article published on 14 December 2001

Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation

scientific article published on 01 April 1994

Critical role of IL-17RA in immunopathology of influenza infection

scientific article

Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice

scientific article

Current approaches to drug therapy for the hypercholesterolemic patient

scientific article

Daniel Steinberg, 1922-2015.

scientific article published on 24 July 2015

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism

scientific article published in March 1987

Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice

scientific article

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice

scientific article

Deletion of the basement membrane heparan sulfate proteoglycan type XVIII collagen causes hypertriglyceridemia in mice and humans

scientific article

Design and Synthesis of a Stable Oxidized Phospholipid Mimic with Specific Binding Recognition for Macrophage Scavenger Receptors ⬇️

scientific article published on September 11, 2012

Detection of two apolipoprotein B species (apoBc and apoBg) by a monoclonal antibody

scientific article published in June 1987

Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a).

scientific article published on 04 July 2013

Development and application of a nonradioactive binding assay of oxidized low-density lipoprotein to macrophage scavenger receptors

scientific article published on 31 August 2013

Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions

scientific article

Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

scientific article

Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles

scientific article published on 11 October 2019

Direct gene transfer to the liver with herpes simplex virus type 1 vectors: transient production of physiologically relevant levels of circulating factor IX

scientific article published on March 1, 1992

Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study

scientific article

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits

scientific article published in May 1990

Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis

scientific article published on 24 September 2019

E06, A NATURAL ANTIBODY TARGETED TO OXIDIZED PHOSPHOLIPIDS, ATTENUATES CARDIAC ISCHEMIA REPERFUSION INJURY IN MICE

scholarly article published in March 2018

Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.

scientific article

Effect of probucol dosage on plasma lipid and lipoprotein levels and on protection of low density lipoprotein against in vitro oxidation in humans

scientific article

Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice ⬇️

scientific article published on May 1, 1998

Effect of the Antioxidant N,N′ -Diphenyl 1,4-Phenylenediamine (DPPD) on Atherosclerosis in ApoE-Deficient Mice ⬇️

scientific article published on October 1, 1995

Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a).

scientific article published on 8 March 2016

Effects of diet on apoprotein E levels and on the apoprotein E subspecies in human plasma lipoproteins

scientific article published on 01 March 1980

Effects of lovastatin therapy on guinea pig low density lipoprotein composition and metabolism

scientific article published in October 1989

Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects

scientific article

Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia ⬇️

scientific article published on November 8, 2012

Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial ⬇️

journal article from 'The Lancet Diabetes & Endocrinology' published in 2021

Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro

scientific article

Enhanced levels of lipoperoxides in low density lipoprotein incubated with murine fibroblast expressing high levels of human 15-lipoxygenase

scientific article published on March 1995

Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta

scientific article

Erratum: A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma

scientific article published on 01 November 2019

Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein

scientific article published on May 1985

Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium

scientific article published on December 2009

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

scientific article

Evidence mandating earlier and more aggressive treatment of hypercholesterolemia

scientific article published on August 2008

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

scientific article published on June 1991

Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

scientific article published on June 1998

Fat-soluble vitamin concentrations in hypercholesterolemic children treated with colestipol

scientific article published on 01 February 1980

Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans

scientific article

Fifty years of research on lipids

scientific article

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts

scientific article

Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein(a)

scientific article published on 08 July 2020

Genetic analysis of a kindred with familial hypobetalipoproteinemia. Evidence for two separate gene defects: one associated with an abnormal apolipoprotein B species, apolipoprotein B-37; and a second associated with low plasma concentrations of apo

scientific article

Glucosylation of low-density lipoproteins to an extent comparable to that seen in diabetes slows their catabolism

scientific article

Helix-loop-helix factor inhibitor of differentiation 3 regulates interleukin-5 expression and B-1a B cell proliferation

scientific article

Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease

scientific article

Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study

scientific article published on 7 May 2015

High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids ⬇️

scientific article published on June 13, 2011

High-density lipoproteins retard the progression of atherosclerosis and favorably remodel lesions without suppressing indices of inflammation or oxidation

scientific article

High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial

scientific article published on 7 September 2004

High-fat, high-cholesterol diet increases the incidence of gastritis in LDL receptor-negative mice

scientific article published in June 2001

High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins

scientific article published on 16 January 2005

Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy

scientific article published on August 2008

Human Oxidation-Specific Antibodies Reduce Foam Cell Formation and Atherosclerosis Progression ⬇️

scientific article published on October 11, 2011

Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo

scientific article

IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitope

scientific article

IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis

scientific article published on August 2004

INHIBITION OF APOLIPOPROTEIN C-III WITH GALNAC CONJUGATED ANTISENSE DRUG POTENTLY LOWERS FASTING SERUM APOLIPOPROTEIN C-III AND TRIGLYCERIDE LEVELS IN HEALTHY VOLUNTEERS WITH ELEVATED TRIGLYCERIDES

scholarly article published in March 2018

Imaging of oxidation-specific epitopes with targeted nanoparticles to detect high-risk atherosclerotic lesions: progress and future directions

scientific article

Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis

scientific article

Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes

scientific article published in December 1998

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis

scientific article

Immunochemical isolation and identification of glucosylated apolipoproteins

scientific article published in January 1986

Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: generation of antibodies specific for derivatized lysine

scientific article published on 01 October 1984

Immunological evidence for the presence of advanced glycosylation end products in atherosclerotic lesions of euglycemic rabbits

scientific article published in May 1995

Immunological responses to oxidized LDL.

scientific article

Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule

scientific article published on 23 October 2006

In Vivo Detection of Oxidation-Specific Epitopes in Atherosclerotic Lesions Using Biocompatible Manganese Molecular Magnetic Imaging Probes ⬇️

scientific article published on February 7, 2012

In memoriam: Roger A. Davis (1945-2008).

scientific article published in November 2008

In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression

scientific article published on March 2000

In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

scientific article published on 21 November 2011

Increased Expression of Oxidation-Specific Epitopes and Apoptosis Are Associated With Haptoglobin Genotype

scientific article published on 01 July 2012

Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression.

scientific article published on 2 November 2006

Influence of C3 deficiency on atherosclerosis

scientific article published in June 2002

Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

scientific article published on 28 November 2012

Inhibition of PCSK9: a powerful weapon for achieving ideal LDL cholesterol levels

scientific article

Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10.

scientific article published on January 2010

Inhibition of the renin-angiotensin system abolishes the proatherogenic effect of uremia in apolipoprotein E-deficient mice

scientific article published on 08 March 2007

Innate and acquired immunity in atherogenesis

scientific article

Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity

scientific article

Innate sensing of oxidation-specific epitopes in health and disease

scientific article published on 27 June 2016

Intensive combination drug therapy of familial hypercholesterolemia with lovastatin, probucol, and colestipol hydrochloride

scientific article published in January 1989

Intensive drug therapy of hypercholesterolemia

scientific article

Interleukin-1 genotypes modulate the long-term effect of lipoprotein(a) on cardiovascular events: The Ioannina Study

scientific article published on 19 December 2017

Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency

scientific article

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

scientific journal article

Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice

scientific article published on 29 August 2013

Intracranial arteries of human fetuses are more resistant to hypercholesterolemia-induced fatty streak formation than extracranial arteries

scientific article

Is atherosclerosis an allergic disease?

scientific article published on 01 October 2011

Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?

scientific article published in April 2002

Isolation, characterization and sequence analysis of five IgG monoclonal anti-beta 2-glycoprotein-1 and anti-prothrombin antigen-binding fragments generated by phage display.

scientific article published on October 1999

Journal of Lipid Research

scientific article published in 2003

LPA Gene, Ethnicity, and Cardiovascular Events

scientific article published on 9 November 2016

Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis

scientific article

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma

scientific article

Lipid metabolism in non-insulin-dependent diabetes: effects of long-term treatment with fructose-supplemented mixed meals.

scientific article published in November 1989

Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations

scientific article published on 27 September 2012

Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids?

scientific article published in September 2003

Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations

scientific article published in January 2005

Lipoperoxides in LDL incubated with fibroblasts that overexpress 15-lipoxygenase.

scientific article published in September 1995

Lipoprotein (a): Coming of Age at Last

scientific article published on 02 February 2016

Lipoprotein B37, a naturally occurring lipoprotein containing the amino-terminal portion of apolipoprotein B100, does not bind to the apolipoprotein B,E (low density lipoprotein) receptor

scientific article

Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake

scientific article published on 21 May 2009

Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation

scientific article published on April 2008

Lipoprotein management in patients with cardiometabolic risk: consensus statement from the American Diabetes Association and the American College of Cardiology Foundation

scientific article

Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis).

scientific article

Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

scientific article

Lipoprotein(a) Reduction in Persons with Cardiovascular Disease

scientific article published on 01 January 2020

Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography

scientific article published on 12 April 2019

Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study

scientific article published on 19 November 2008

Lipoproteins accumulate in immune deposits and are modified by lipid peroxidation in passive Heymann nephritis

scientific article published on October 1996

Lipoproteins in normal and atherosclerotic aorta

scientific article published on August 1990

Lipoproteins in pinnipeds: analysis of a high molecular weight form of apolipoprotein E.

scientific article published on June 1991

Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members

scientific article

Local expression of platelet-activating factor-acetylhydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic

scientific article

Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function

scientific article published in February 2004

Long-term mipomersen treatment is associated with a reduction in cardiovascular events in patients with familial hypercholesterolemia

scientific article

Long-term transgene expression from genetically modified hepatocytes grafted to the rat liver

scientific article published on March 1, 1992

Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis

scientific article

Low density lipoprotein undergoes oxidative modification in vivo

scientific article

Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia

scientific article

Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a).

scientific article published on 13 October 2003

MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma ⬇️

scientific article published on May 10, 2013

Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage

scientific article published on 23 March 2009

Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans ⬇️

scientific article published on February 1, 1992

Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts

scientific article

Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions ⬇️

scientific article published on November 15, 1991

Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.

scientific article

Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies

scientific article

Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits

scientific article published in November 2001

Maternal hypercholesterolemia enhances atherogenesis in normocholesterolemic rabbits, which is inhibited by antioxidant or lipid-lowering intervention during pregnancy: an experimental model of atherogenic mechanisms in human fetuses

scientific article published in November 2000

Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk

scientific article published on 01 April 2001

Mechanical aortic injury in apoE-deficient mice as a model for development of atherosclerosis: demonstration of leukocyte rolling early after injury

scientific article

Metabolic and immunological consequences of glycation of low density lipoproteins

scientific article

Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells

scientific article published on 6 November 2002

Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophages.

scientific article

Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials

scientific article

Mobilization of stored triglycerides from macrophages as free fatty acids

scientific article published on November 1984

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids

scientific article

Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway

scientific article

Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates

scientific article published in November 1992

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition

scientific article published on May 1999

Monoclonal antibody MB19 detects genetic polymorphism in human apolipoprotein B

scientific article published on February 1986

Monoclonal antibody detects Ag polymorphism of apolipoprotein B

scientific article published on 01 June 1986

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

scientific article

Murine models for study of lipoprotein metabolism and atherosclerosis

scientific article published on August 1993

Mycophenolate Mofetil Decreases Atherosclerotic Lesion Size by Depression of Aortic T-Lymphocyte and Interleukin-17–Mediated Macrophage Accumulation ⬇️

scientific article published on May 24, 2011

N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels

scientific article published on 01 September 2019

NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis

scientific article published in January 2018

Natural antibodies in murine atherosclerosis

scientific article published on March 2008

Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

scientific article

Neo-self antigens and the expansion of B-1 cells: lessons from atherosclerosis-prone mice

scientific article

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

scientific article published on 21 November 2019

Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice

scientific article published on 19 July 2021

New Commentary section to highlight significantJLRarticles

scientific article published in 2007

New therapeutic targets for calcific aortic valve stenosis: the lipoprotein(a)-lipoprotein-associated phospholipase A2-oxidized phospholipid axis

scientific article published on 23 October 2013

Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH

scientific article published on 27 February 2020

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

scientific article published on 28 April 2020

Nonenzymatic glucosylation of high-density lipoprotein accelerates its catabolism in guinea pigs

scientific article published on 01 November 1982

Nonenzymatic glucosylation of homologous low density lipoprotein and albumin renders them immunogenic in the guinea pig.

scientific article published on May 1983

Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activity

scientific article published in April 1982

Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100.

scientific article

Normalization on triglycerides in type IV hyperlipoproteinemia fails to correct low levels of high-density-lipoprotein cholesterol

scientific article published on 01 October 1980

Oxidation-specific biomarkers and risk of peripheral artery disease

scientific article published on 26 March 2013

Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events

scientific article published on September 2010

Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events

scientific article published on November 2012

Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis ⬇️

scientific article published on March 28, 2013

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity

scientific article published on January 2011

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

scientific article published on 13 April 2009

Oxidation-specific epitopes restrain bone formation.

scientific article published on 6 June 2018

Oxidative damage in multiple sclerosis lesions ⬇️

scientific article

Oxidized Low-Density Lipoprotein and Atherosclerosis ⬇️

scientific article published on December 1, 2010

Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease: The Copenhagen General Population Study

scientific article published in June 2017

Oxidized Phospholipids on Apolipoprotein B-100 and Recurrent Ischemic Events Following Stroke or Transient Ischemic Attack

scientific article published in January 2017

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans ⬇️

scientific article published on 05 August 2016

Oxidized Phospholipids on apoB-100-Containing Lipoproteins: a Biomarker Predicting Cardiovascular Disease and Cardiovascular Events ⬇️

scientific article published on October 1, 2011

Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis

scientific article published on September 2015

Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation

scientific article

Oxidized low density lipoprotein and innate immune receptors ⬇️

scientific article published on October 1, 2003

Oxidized low density lipoproteins in atherogenesis: role of dietary modification

scientific article published on January 1996

Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study

scientific article published on 30 May 2006

Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin

scientific article published on 17 April 2006

Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions

scientific article published in January 2002

Oxidized phospholipids and isoprostanes in atherosclerosis

scientific article published in October 1998

Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction

scientific article published in April 2012

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

scientific article published in Nature

Oxidized phospholipids impair pulmonary antibacterial defenses: Evidence in mice exposed to cigarette smoke ⬇️

scientific article published on August 22, 2012

Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study

scientific article

Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease

scientific article

Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors.

scientific article published on May 2000

Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study

scientific article

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis

scientific article published in January 2018

Parallel expression of the MB19 genetic polymorphism in apoprotein B-100 and apoprotein B-48. Evidence that both apoproteins are products of the same gene

scientific article published on 01 March 1986

Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease

scientific article

Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein

scientific article published on 7 June 2004

Phosphocholine as a pattern recognition ligand for CD36.

scientific article

Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses

scientific article

Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E.

scientific article published on 24 June 2002

Plasma Proteomics for Epidemiology: Increasing Throughput With Standard-Flow Rates

scientific article published in December 2017

Plasma triacylglycerol and HDL cholesterol concentrations confirm self-reported changes in carbohydrate and fat intakes in women in a diet intervention trial.

scientific article published in February 2004

Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.

scientific article published on 12 May 2003

Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages

scientific article

Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study

scientific article published on 31 January 2016

Post-transcriptional regulation of retroviral vector-transduced low density lipoprotein receptor activity.

scientific article published on December 1990

Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis

scientific article published on 24 September 2019

Pre-eclampsia and serum antibodies to oxidised low-density lipoprotein

scientific article published on 01 March 1994

Pro-inflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a).

scientific article

Probucol inhibits oxidative modification of low density lipoprotein

scientific article

Promise of immune modulation to inhibit atherogenesis

scientific article published on 23 July 2007

Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance

scientific article

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

scientific article published in Nature

RNA-Targeted Therapeutics

scientific article published on 01 April 2018

RNA-Targeted Therapeutics

scientific article published on 01 February 2019

Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

scientific article published in January 1994

Radioiodination of low density lipoprotein initiates lipid peroxidation: protection by use of antioxidants

scientific article published in September 1993

Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo

scientific article published on January 1999

Re-evaluation of the anticoagulant properties of high-density lipoprotein-brief report

scientific article published on 30 December 2014

Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits ⬇️

scientific article published on July 25, 1982

Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells

scientific article published on May 1999

Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization

scientific article published on 4 November 2004

Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling

scientific article

Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results

scientific article published on 4 February 2016

Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids

scientific article published on 01 January 2019

Relationship between "LDL-C", estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide

scientific article published on 01 March 2018

Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study

scientific article published in July 2008

Relationship of Autoantibodies to MDA-LDL and ApoB-Immune Complexes to Sex, Ethnicity, Subclinical Atherosclerosis, and Cardiovascular Events

scientific article published on 04 May 2017

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

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Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events

scientific article published on 8 November 2006

Relationship of a comprehensive panel of plasma oxidized low-density lipoprotein markers to angiographic restenosis in patients undergoing percutaneous coronary intervention for stable angina

scientific article published on 01 November 2005

Relationship of lipoprotein(a) molar concentrations and mass according to lipoprotein(a) thresholds and apolipoprotein(a) isoform size

scientific article published on 20 July 2018

Relationship of lipoprotein-associated apolipoprotein C-III with lipid variables and coronary artery disease risk: The EPIC-Norfolk prospective population study

scientific article published on 29 August 2018

Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myo

scientific article

Relationship of oxidized phospholipids on apolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study

scientific article published on 23 March 2009

Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial

scientific article

Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans

scientific article

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells

scientific article

Risk factors for cardiovascular disease in systemic lupus erythematosus

scientific article

Role of oxidised low density lipoprotein in atherogenesis

scientific article

Role of oxidized low density lipoprotein in atherogenesis

scientific article published on December 1991

Rosuvastatin: an independent analysis of risks and benefits

scientific article published on 14 June 2006

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL.

scientific article published in January 2015

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein

scientific article published in September 2001

Scavenger receptors, oxidized LDL, and atherosclerosis

scientific article

Secretion of lipoprotein lipase by macrophages in culture

scientific article published on 01 July 1981

Selective alpha-blockade versus angiotensin-converting enzyme inhibition as initial antihypertensive therapy. Effects on circulating lipoproteins

scientific article published in January 1989

Shared Mechanisms between Cardiovascular Disease and NAFLD ⬇️

scientific article published on 25 August 2022

Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century

scientific article published on 01 December 2002

Short-term feeding of atherogenic diet to mice results in reduction of HDL and paraoxonase that may be mediated by an immune mechanism

scientific article published on August 2000

Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells

scientific article

Splenic immunity and atherosclerosis: a glimpse into a novel paradigm?

scientific article

Statin therapy increases lipoprotein(a) levels

scientific article published on 20 May 2019

Statins and increases in Lp(a): an inconvenient truth that needs attention

scientific article published on 01 January 2020

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo

scientific article

Structure, immunology, and cell reactivity of low density lipoprotein from umbilical vein of a newborn type II homozygote

scientific article published on July 1980

Studies on the ability of dietary supplementation with beta-carotene to protect low-density lipoprotein from oxidative modification

scientific article published in December 1993

Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice

scientific article

T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses

scientific article

Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes

scientific article published on 9 June 2008

Targeting APOC3 in the familial chylomicronemia syndrome

scientific article published on December 2014

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes

scientific article published in February 2003

Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)Rx and IONIS-APO(a)-LRx antisense oligonucleotide clinical trials.

scientific article published on 2 November 2017

The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68

scientific article

The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis

scientific article published on 29 March 2012

The Effects of 2'-O-Methoxyethyl Containing Antisense Oligonucleotides on Platelets in Human Clinical Trials

scientific article

The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles

scientific article published on 12 October 2009

The Oxidative Modification Hypothesis of Atherosclerosis Does It Hold for Humans? ⬇️

scientific article published on April 1, 2001

The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis

scientific article published in 2022

The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells

scientific article

The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein

scientific journal article

The burden of familial chylomicronemia syndrome: Results from the global IN-FOCUS study

scientific article published on 26 April 2018

The burden of familial chylomicronemia syndrome: interim results from the IN-FOCUS study

scientific article published on 24 March 2017

The influence of innate and adaptive immune responses on atherosclerosis

scientific article

The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans

scientific article published on April 2008

The inhibitory FcγRIIb modulates the inflammatory response and influences atherosclerosis in male apoE−/− mice ⬇️

scientific article published on October 20, 2010

The role of innate immunity in atherogenesis

scientific article published on 22 December 2008

The role of lipoprotein lipase in the metabolism of triglyceride-rich lipoproteins by macrophages.

scientific article published on August 1983

The role of natural antibodies in atherogenesis

scientific article

The role of oxidized LDL in atherogenesis: immunological response and anti-phospholipid antibodies

scientific article published on April 1997

The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis

scientific article

The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity

scientific article

To E or not to E--how do we tell?

scientific article published on 01 December 1998

Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages.

scientific article

Turnover and tissue sites of degradation of glucosylated low density lipoprotein in normal and immunized rabbits.

scientific article published in September 1987

Type III hyperlipoproteinemia: development of a VLDL ApoE gel isoelectric focusing technique and application in family studies

scientific article published on April 1, 1979

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia

scientific article published on 11 February 2020

Uptake and degradation of human chylomicrons by macrophages in culture. Role of lipoprotein lipase

scientific article published on 01 September 1983

Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish

scientific article

Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III.

scientific article

Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

scientific article published on 01 August 2019

Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia

scholarly article

Volanesorsen, Familial Chylomicronemia Syndrome, and Thrombocytopenia. Reply

scientific article published on 01 December 2019

Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia

scientific article published on 29 August 2020

When monocytes come (too) close to our hearts

scientific article published on 01 April 2010

You are right too!

scientific article

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