List of works - Gregory E. Crawford

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

scientific article

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

scientific article published on April 2013

A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function

scientific article

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

scientific article (publication date: May 2012)

Abstract B44: Chromatin structure impacts androgen receptor transcriptional specificity in prostate cancer cell lines

Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

scientific article published on February 2007

Allele-specific and heritable chromatin signatures in humans

scientific article published on 16 September 2010

An encyclopedia of mouse DNA elements (Mouse ENCODE).

scientific article

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression

scientific article

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

scientific article

Case conferencing for palliative care patients - a survey of South Australian general practitioners

scientific article published on 26 September 2017

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

scientific article

Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma

scientific article

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

scientific article

Combined reflectance spectroscopy and stochastic modeling approach for noninvasive hemoglobin determination via palpebral conjunctiva

scientific article

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee

scientific article published in March 2018

Correction: Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

scientific article published on 28 April 2015

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

scientific article published on November 2016

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

scientific article published in December 2017

DNA methylation and differentiation: HOX genes in muscle cells ⬇️

scientific article published on 02 August 2013

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

scientific article

DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types

scientific article published on 8 May 2013

DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells

scientific article

DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2

scientific article

DNase I sensitivity QTLs are a major determinant of human expression variation

scientific article

Defining functional DNA elements in the human genome

scientific article

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

scientific article published on 9 January 2014

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

scientific article published on 15 December 2015

Digital imaging, spectroscopy, and liquid crystals in a hand-held, non-invasive device to determine hemoglobin concentration

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

scientific article

Dissecting the regulatory architecture of gene expression QTLs

scientific article published on 31 January 2012

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

scientific article (publication date: March 2007)

Dynamic DNA methylation across diverse human cell lines and tissues

scientific article published on 16 January 2013

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

scientific article

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

scientific article published on 2 February 2012

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

scientific article published on 13 May 2010

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

scientific article

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection

scientific article

F-Seq: a feature density estimator for high-throughput sequence tags

scientific article

Gene expression during normal and FSHD myogenesis ⬇️

scientific article published on September 27, 2011

Genetic and epigenetic determinants of inter-individual variability in responses to toxicants

article

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

scientific article

Genome accessibility is widely preserved and locally modulated during mitosis

scientific article

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide identification of regulatory elements in Sertoli cells

scientific article published on 13 January 2017

Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)

scientific article

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

scientific article published on 29 May 2015

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

scientific article

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

scientific article published on 27 February 2009

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

scientific article

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites ⬇️

scientific article published on May 28, 2012

HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells

scientific article published on 16 April 2016

Heritable individual-specific and allele-specific chromatin signatures in humans

scientific article

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

scientific article

High-resolution mapping and characterization of open chromatin across the genome

scientific article

High-resolution mapping of open chromatin in the rice genome

scientific article published on 22 November 2011

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

scientific article

Histone modifications at human enhancers reflect global cell-type-specific gene expression

scientific article (publication date: 7 May 2009)

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

article published in 2018

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

scientific article published in June 2007

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

scientific article

Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites

scientific article

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

scientific article

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

scientific article

Interferon regulatory factors are transcriptional regulators of adipogenesis

scientific article published on January 2008

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

scholarly article

Major mental illness and violence history as predictors of institutional misconduct and recidivism: main and interaction effects

scientific article published on 14 October 2013

Mapping nucleosome positions using DNase-seq

scientific article published on 15 January 2016

Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip).

scientific article published in January 2009

Mesoscale Three Dimensional Lattices Formed in Polymer Dispersed Liquid Crystals: A Diamond-Like Face Centered Cubic

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

scientific article

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

scientific article

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

scientific article published on July 2010

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes

scientific article

Non-invasive determination of hemoglobin by digital photography of palpebral conjunctiva

scientific article

Noninvasive optical, electrical, and acoustic methods of total hemoglobin determination

scientific article published on 10 December 2007

Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine

scientific article

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

scientific article

Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function

scientific article

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

scientific article published on 12 March 2013

Photonics-based in vivo total hemoglobin monitoring and clinical relevance

scientific article published on May 2009

Point-of-care noninvasive hemoglobin determination using fiber optic reflectance spectroscopy

scientific article published in January 2007

Predicting cell-type-specific gene expression from regions of open chromatin

scientific article published on September 2012

Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

scientific article

Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9.

scientific article

Reflectance spectrometry of normal and bruised human skins: experiments and modeling

scientific article published on January 19, 2012

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

scientific article published on 6 April 2015

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease

scientific article published on August 2014

Retroviral DNA integration: viral and cellular determinants of target-site selection

scientific article published on 23 June 2006

Roles of the state asthma program in implementing multicomponent, school-based asthma interventions

scientific article

Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing

scientific article published in January 2018

Site-specific silencing of regulatory elements as a mechanism of X inactivation

scientific article

Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays

scientific article published on January 2006

Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation

scientific article

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

scientific article published on 3 February 2013

The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes ⬇️

scientific article published on July 16, 2012

The PsychENCODE project

scientific article

The accessible chromatin landscape of the human genome

scientific article

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

scientific article published on 29 June 2016

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription

scientific article published on 10 February 2018

Tolerance of the skull to blunt ballistic temporo-parietal impact

scientific article published on 11 August 2009

Using Positive Organizational Scholarship in Healthcare and Video Reflexive Ethnography to Examine Positive Deviance to New Public Management in Healthcare

scientific article published in February 2018

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice

scientific article

List of works by Gregory E. Crawford

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

Abstract B44: Chromatin structure impacts androgen receptor transcriptional specificity in prostate cancer cell lines

Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

Allele-specific and heritable chromatin signatures in humans

An encyclopedia of mouse DNA elements (Mouse ENCODE).

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Case conferencing for palliative care patients - a survey of South Australian general practitioners

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

Combined reflectance spectroscopy and stochastic modeling approach for noninvasive hemoglobin determination via palpebral conjunctiva

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee

Correction: Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

DNA methylation and differentiation: HOX genes in muscle cells ⬇️

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types

DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells

DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2

DNase I sensitivity QTLs are a major determinant of human expression variation

Defining functional DNA elements in the human genome

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Digital imaging, spectroscopy, and liquid crystals in a hand-held, non-invasive device to determine hemoglobin concentration

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Dissecting the regulatory architecture of gene expression QTLs

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Dynamic DNA methylation across diverse human cell lines and tissues

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection

F-Seq: a feature density estimator for high-throughput sequence tags

Gene expression during normal and FSHD myogenesis ⬇️

Genetic and epigenetic determinants of inter-individual variability in responses to toxicants

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

Genome accessibility is widely preserved and locally modulated during mitosis

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Genome-wide identification of regulatory elements in Sertoli cells

Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites ⬇️

HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells

Heritable individual-specific and allele-specific chromatin signatures in humans

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

High-resolution mapping and characterization of open chromatin across the genome

High-resolution mapping of open chromatin in the rice genome

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Histone modifications at human enhancers reflect global cell-type-specific gene expression

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

Interferon regulatory factors are transcriptional regulators of adipogenesis

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

Major mental illness and violence history as predictors of institutional misconduct and recidivism: main and interaction effects

Mapping nucleosome positions using DNase-seq

Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip).

Mesoscale Three Dimensional Lattices Formed in Polymer Dispersed Liquid Crystals: A Diamond-Like Face Centered Cubic

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes

Non-invasive determination of hemoglobin by digital photography of palpebral conjunctiva