List of works - Alexias Safi

A Region of the Nucleosome Required for Multiple Types of Transcriptional Silencing in Saccharomyces cerevisiae ⬇️

scientific article published on May 5, 2011

Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.

scientific article published on 15 February 2006

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

scientific article

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee.

scientific article published in March 2018

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

scientific article published on 15 December 2015

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

scientific article

Evolution of new function through a single amino acid change in the yeast repressor Sum1p

scientific article published on 11 February 2008

Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate.

scientific article

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

scientific article

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

scientific article published on 29 May 2015

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

scientific article

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

scientific article

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

article published in 2018

Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones

scientific article published on June 2003

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

scientific article

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

scientific article published on 12 March 2013

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

scientific article published on 6 April 2015

Role for the pleckstrin homology domain-containing protein CKIP-1 in phosphatidylinositol 3-kinase-regulated muscle differentiation.

scientific article published on February 2004

The accessible chromatin landscape of the human genome

scientific article

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription

scientific article published on 10 February 2018

Transcriptome and epigenome landscape of human cortical development modeled in organoids

scientific article

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice

scientific article

List of works by Alexias Safi

A Region of the Nucleosome Required for Multiple Types of Transcriptional Silencing in Saccharomyces cerevisiae ⬇️

Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee.

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Evolution of new function through a single amino acid change in the yeast repressor Sum1p

Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate.

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

Role for the pleckstrin homology domain-containing protein CKIP-1 in phosphatidylinositol 3-kinase-regulated muscle differentiation.

The accessible chromatin landscape of the human genome

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription

Transcriptome and epigenome landscape of human cortical development modeled in organoids

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice