List of works by Kurt Zatloukal

24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

scientific article published in February 2006

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

A New Technology for Stabilization of Biomolecules in Tissues for Combined Histological and Molecular Analyses

A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

scientific article

A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis

scientific article (publication date: 21 December 2016)

A lymphotoxin-driven pathway to hepatocellular carcinoma

scientific article published on October 2009

A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis

scientific article

Accelerating the Development and Validation of New Value-Based Diagnostics by Leveraging Biobanks

scientific article published on June 2016

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

scientific article

Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous normal-appearing endometrial and myometrial tissues

scientific article published on 01 December 2004

Alterations in Human Liver Metabolome during Prolonged Cryostorage

scientific article

Analysis of biomedical data with multilevel glyphs

scientific article

Animal models of NAFLD from the pathologist's point of view

scientific article published on 08 May 2018

Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner

scientific article

Automatic classification of histopathological diagnoses for building a large scale tissue catalogue.

scientific article published on 22 December 2016

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

scientific article

Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis

scientific article published on 22 February 2008

Bile acid-induced Mallory body formation in drug-primed mouse liver

scientific article published on December 2002

Biobanking for Europe

scientific article

Biobanks for life sciences and personalized medicine: importance of standardization, biosafety, biosecurity, and data management

scientific article published on 30 December 2019

Biobanks: transnational, European and global networks

scientific article published on September 2007

Bridging the translational innovation gap through good biomarker practice.

scientific article published on 28 April 2017

Bringing the cell nucleus in the focus of NAFLD

scientific article published on 26 March 2018

CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice

scientific article published in August 2005

Caleydo: connecting pathways and gene expression

scientific article published on 20 July 2009

Causability and explainability of artificial intelligence in medicine

scientific article published on 02 April 2019

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

scientific article

Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.

scientific article

Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis

scientific article published on 19 October 2016

Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis

scientific article published on 20 October 2016

Characterization of iPSCs derived from dermal fibroblasts from a healthy 19year old female

scientific article published on 19 October 2016

Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation.

scientific article published in December 2017

Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro

scientific article

Clusterin expression in cholestasis, hepatocellular carcinoma and liver fibrosis

scientific article

Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains

scientific article

Comprehensive catalog of European biobanks

scientific article published on 8 September 2011

Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.

scientific article published on 27 May 2011

Current trends in biobanking for rare diseases: a review [Corrigendum]

scientific article published in March 2015

Cytokeratins as targets for bile acid-induced toxicity

scientific article published on February 2002

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

scientific article

Effects of intra- and post-operative ischemia on the metabolic profile of clinical liver tissue specimens monitored by NMR.

scientific article published on 29 October 2013

Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling

scientific article

Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): potential basis for a new therapeutic approach

scientific article

Enhancing Reuse of Data and Biological Material in Medical Research: From FAIR to FAIR-Health

scientific article published on 23 January 2018

Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells

scientific article

Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype

scientific article published on 25 July 2018

Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype

scientific article published on 27 July 2018

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial

scientific article published on 2 August 2014

Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis

scientific article published on September 2007

FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors

scientific article published on 25 February 2015

Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts

scientific article

From Mallory to Mallory-Denk bodies: what, how and why?

scientific article published on 27 April 2007

From the evaluation of existing solutions to an all-inclusive package for biobanks

scientific article published on 12 January 2017

Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis

scientific article

Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model

scientific article published on 26 March 2012

Genetic deletion of keratin 8 corrects the altered bone formation and osteopenia in a mouse model of cystic fibrosis

scientific article published on 13 January 2016

Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copy-number- and mutation-analysis

scientific article published on 14 May 2009

Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy

scientific article published on 25 August 2011

Hepatobiliary transporter expression in human hepatocellular carcinoma.

scientific article published in April 2005

Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress

scientific article published on 18 June 2007

Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis

scientific article published on 25 November 2016

Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase

scholarly article

High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications

scientific article (publication date: 2013)

Histological assessment of PAXgene tissue fixation and stabilization reagents

scientific article (publication date: 2011)

Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo

scientific article

Human tissue biobanks as instruments for drug discovery and development: impact on personalized medicine

article

ITFoM – The IT Future of Medicine

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

scientific article published on December 2006

Immunofluorescence and Immunohistochemical Detection of Keratins

scientific article published on 24 October 2015

Immunohistochemical analysis of Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis

scientific article

Impact of storage conditions on the quality of nucleic acids in paraffin embedded tissues

scientific article published in PLoS ONE

Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma.

scientific article published on 19 August 2016

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

scientific article published on 26 October 2009

In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.

scientific article published on September 2007

Inactivation of Influenza A virus, Adenovirus, and Cytomegalovirus with PAXgene tissue fixative and formalin

scientific article

Individual Human Metabolic Phenotype Analyzed by (1)H NMR of Saliva Samples.

scientific article published on 3 May 2016

Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice

scientific article published in January 2002

Insights into molecular mechanisms contributing to individual susceptibility to steatohepatitis: lessons learned from mouse models

scientific article published on 01 June 2012

Interaction of stress proteins with misfolded keratins

scientific article published in March 2005

Intermediate filament protein inclusions.

scientific article published in January 2004

Inverse correlation of secreted frizzled-related protein 4 and beta-catenin expression in endometrial stromal sarcomas

scientific article

JAZF1/JJAZ1 gene fusion in endometrial stromal sarcomas: molecular analysis by reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded tissue

scientific article published on August 2005

Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.

scientific article published on 28 September 2016

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells

scientific article published on January 2013

Limiting factors for wearing personal protective equipment (PPE) in a health care environment evaluated in a randomised study

scientific article published in PLoS ONE

Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.

scientific article

Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.

scientific article

Machine Learning and Knowledge Extraction in Digital Pathology Needs an Integrative Approach

scholarly article by Andreas Holzinger et al published 2017 in Lecture Notes in Computer Science

Machine learning enhanced virtual autopsy

scientific article published in October 2017

Mallory body formation in primary biliary cirrhosis is associated with increased amounts and abnormal phosphorylation and ubiquitination of cytokeratins

scientific article published on 01 April 2003

Mallory body--a disease-associated type of sequestosome

scientific article published in May 2002

Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway

scientific article published on 6 September 2016

Molecular mechanisms of endometrial stromal sarcoma and undifferentiated endometrial sarcoma as premises for new therapeutic strategies

scientific article

Molecularly characterised xenograft tumour mouse models: valuable tools for evaluation of new therapeutic strategies for secondary liver cancers

scientific article published on 15 March 2009

Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes

scientific article

Murine Genetic Background Overcomes Gut Microbiota Changes to Explain Metabolic Response to High-Fat Diet

scientific article published on 21 January 2020

Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers

scientific article published on July 2002

Oncosis represents the main type of cell death in mouse models of cholestasis

scientific article published in March 2005

Pathogen Inactivating Properties and Increased Sensitivity in Molecular Diagnostics by PAXgene, a Novel Non-Crosslinking Tissue Fixative

scientific article

Pathology as the cornerstone of human tissue banking: European consensus expert group report

scientific article published on September 2009

Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth

scientific article published on June 2005

Pre-analytical processes in medical diagnostics: New regulatory requirements and standards

scientific article published on 15 May 2019

Profiles of chemokine receptors in melanocytic lesions: de novo expression of CXCR6 in melanoma

scientific article published on 15 February 2007

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

scientific article published on 6 November 2008

Proteomic analysis of PAXgene-fixed tissues

scientific article

Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation

scientific article published on 25 December 2017

Protocol for HER2 FISH determination on PAXgene-fixed and paraffin-embedded tissue in breast cancer

scientific article published on 08 June 2016

Public-private relationships in biobanking: a still underestimated key component of open innovation

scientific article published on 14 December 2013

Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking

scientific article

Quality control of RNA preservation and extraction from paraffin-embedded tissue: implications for RT-PCR and microarray analysis

scientific article

Quality management at the national biobanking level - establishing a culture of mutual trust and support: the BBMRI.at example

scientific article published on 01 November 2019

RD-Connect: an integrated platform connecting databases, registries, biobanks and clinical bioinformatics for rare disease research

scientific article

Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

scientific article published in July 2004

Role of Academic Biobanks in Public-Private Partnerships in the European Biobanking and BioMolecular Resources Research Infrastructure Community

scientific article published on 30 November 2018

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

scientific article published in September 2003

Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

scientific article published in October 2003

Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver

scientific article published on 7 July 2005

Safeguarding donors' personal rights and biobank autonomy in biobank networks: the CRIP privacy regime

scientific article published on 15 July 2010

Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies

scientific article

Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice

scientific article published on 20 June 2016

Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma

scientific article published on 15 April 2019

Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice

scientific article

Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis

scientific article

State-of-the-Art and Future Challenges in the Integration of Biobank Catalogues

scientific article published in 2015

Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration

scientific article published on 23 October 2019

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

scientific article published on 23 November 2017

TAMEE: data management and analysis for tissue microarrays

scientific article

The EuroBioBank Network: 10 years of hands-on experience of collaborative, transnational biobanking for rare diseases

scientific article

The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.

scientific article published on 6 October 2010

The PAXgene(®) tissue system preserves phosphoproteins in human tissue specimens and enables comprehensive protein biomarker research

scientific article

The PPARα Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity

scientific article published in Scientific Reports

The differentiation antigen NY-BR-1 is a potential target for antibody-based therapies in breast cancer

scientific article

The impact of crosslinking and non-crosslinking fixatives on antigen retrieval and immunohistochemistry

scientific article published on 11 May 2019

The impact of free or standardized lifestyle and urine sampling protocol on metabolome recognition accuracy

scientific article

The keratin cytoskeleton in liver diseases

scientific article published in November 2004

The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.

scientific article published in September 2009

The role of the pathologist in tissue banking: European Consensus Expert Group Report

scientific article

The tumor-associated shift in immunoglobulin G1/G2 is expressed at the messenger RNA level of peripheral blood B lymphocytes in patients with gynecologic malignancies

scientific article published on 01 January 2000

Toward a roadmap in global biobanking for health

scientific article (publication date: November 2012)

Transition between acute and chronic hepatotoxicity in mice is associated with impaired energy metabolism and induction of mitochondrial heme oxygenase-1.

scientific article

Transnational access to large prospective cohorts in Europe: current trends and unmet needs

scientific article published on 17 October 2018

Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles

scientific article published in October 2002

Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells

scientific article published on September 2006

Variability of protein and phosphoprotein levels in clinical tissue specimens during the preanalytical phase

scientific article published on 16 November 2012

Virtual autopsy: Machine Learning and AI provide new opportunities for investigating minimal tumor burden and therapy resistance by cancer patients

scientific article published in January 2018

What are the next steps to overcoming roadblocks to transnational biobank collaboration?

scientific article published on 01 February 2012

miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis

scientific article

p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

scientific article published on January 2002

p62 protein is expressed in pancreatic beta cells

scientific article published on 01 August 2005

p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies

scientific article (publication date: 2016)

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