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List of works by Daniel Peeper

A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis

scientific article published on 04 May 2009

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence

scientific article

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma

scientific article published on 10 October 2019

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

scientific article published on 19 May 2013

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis

scientific article

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in non-small cell lung cancer

scientific article published on 24 May 2019

Antagonistic TSC22D1 variants control BRAFE600-induced senescence ⬇️

scientific article published on March 29, 2011

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

scientific article published on 11 July 2019

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

scientific article published on 01 January 2020

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

correction of a scholarly article

Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence

scientific article published on 8 September 2015

B cells and tertiary lymphoid structures promote immunotherapy response

scientific article published on 15 January 2020

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts

scientific article published on 16 June 2016

BRAFE600-associated senescence-like cell cycle arrest of human naevi

scientific article (publication date: 4 August 2005)

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

scientific article published on 4 October 2017

Cellular senescence in vivo: a barrier to tumorigenesis

scientific article published on 18 March 2008

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux

scientific article published on 26 November 2019

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

scientific article published on 01 June 2020

Comment on “Absence of Senescence-Associated β-Galactosidase Activity in Human Melanocytic Nevi In Vivo”

scientific article published in June 2008

Comprehensive analysis of cutaneous and uveal melanoma liver metastases

scientific article published on 01 December 2020

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

scientific article

Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors.

scientific article published on 15 January 2018

CopywriteR: DNA copy number detection from off-target sequence data

scientific article

Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis

scientific article published on 01 July 2007

Cross-species oncogenomics in cancer gene identification

scientific article

Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib

scientific article

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest

scientific article published on July 2002

Erratum: Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

scientific article published in Nature

Evidence of oncogene-induced senescence in thyroid carcinogenesis.

scientific article published in December 2011

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice

scientific article published on 01 March 2020

Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival

scientific article published on 3 December 2015

Frequent clonal relations between metastases and non-index prostate cancer lesions

article

Functional Characterization of Human Cancer-Derived TRKB Mutations ⬇️

scientific article published on February 17, 2011

Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.

scientific article

Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma

scientific article published on 17 April 2013

High-Throughput Assessment of Kinome-wide Activation States

scientific article published on 11 September 2019

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis ⬇️

scientific article published on March 12, 2013

Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial

scientific article published on 31 May 2019

If you can’t beat me, join me: collaborating oncogenes circumventing senescence and causing cancer ⬇️

scientific article published on August 1, 2011

Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

scientific article published on 22 June 2016

Interrogating open issues in cancer medicine with patient-derived xenografts

scientific article published on 15 September 2017

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

scientific article published on 20 January 2017

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts

scientific article

KLF4, p21 and context-dependent opposing forces in cancer

scientific article

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

scientific article published on 15 December 2014

MITF: More Interesting Traits, Folks!

scientific article published on 31 March 2016

Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities

scientific article published on 03 June 2019

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence

scientific article published on 15 September 2017

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma

scientific article published on 14 May 2014

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma

scientific article published on 22 December 2021

Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation.

scientific article published on 25 April 2016

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma

scientific article published on 08 October 2018

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

scientific article

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

scientific article published in November 2017

Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition.

scientific article published on 6 November 2014

Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy.

scientific article

Phenotypic diversity drives paracrine drug tolerance.

scientific article published on 10 July 2017

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

scientific article published on 28 August 2015

Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence

scientific article

Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4

scientific article published on 06 July 2021

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

scientific article

Proteomics and Phosphoproteomics Profiling of Drug-Addicted BRAFi-Resistant Melanoma Cells

scientific article published on 03 August 2021

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

scientific article

Rational Cancer Treatment Combinations: An Urgent Clinical Need

scientific article published on 01 June 2020

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

scientific article published on 07 August 2020

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

scientific article published on 20 March 2015

SUMOylation of DRIL1 directs its transcriptional activity towards leukocyte lineage-specific genes

scientific article

Senescence-messaging secretome: SMS-ing cellular stress

scientific article published on 09 January 2009

Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

scientific article published on 2 June 2015

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

scientific journal article

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

scientific article

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

scientific article published on 5 March 2018

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

scientific article published on 01 April 2018

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

scientific article published in February 2018

The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

scientific article

The essence of senescence

scientific article

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

scientific article

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

scientific article published on 11 March 2008

The neurotrophic receptor TrkB in anoikis resistance and metastasis: a perspective

scientific article

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

scientific article published on 09 March 2022

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling

scientific article published on 08 April 2022

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter s

scientific article published on 15 September 2017

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

scholarly article by Roelof J C Kluin published in October 2018

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