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List of works by Sven-Erik Dahlén

A Topological Data Analysis Network Model of Asthma Based on Blood Gene Expression Profiles

article

A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED

scientific article published on 15 February 2017

A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze

scientific article published on 12 October 2016

A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig

scientific article published on 21 July 2020

A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma

scientific article published on 08 January 2009

Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung

scientific article published on 11 January 2016

Acute effects of beclomethasone on hyperpnea-induced bronchoconstriction

scientific article published in February 2010

Aggregates of ultrafine particles impair phagocytosis of microorganisms by human alveolar macrophages

scientific article published on 19 September 2005

Aggregates of ultrafine particles modulate lipid peroxidation and bacterial killing by alveolar macrophages.

scientific article published on 15 February 2007

An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells

article published in 2018

Antagonising EP1 and EP2 receptors reveal that the TP receptor mediates a component of antigen-induced contraction of the guinea pig trachea

scientific article

Application of 'omics technologies to biomarker discovery in inflammatory lung diseases

scientific article published on 08 February 2013

Application of Metabolomics Approaches to The Study of Respiratory Diseases ⬇️

scientific article published on September 1, 2012

Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B4 in saliva: effects of treatment with zileuton

scientific article published on 25 January 2007

Association of endopeptidases, involved in SARS-CoV-2 infection, with microbial aggravation in sputum of severe asthma

scientific article published on 07 January 2021

Asthma Treatment Guidelines Meet the Real World

scientific article published on 5 May 2011

Asthma research in Europe: a transformative agenda for innovation and competitiveness.

scientific article published in May 2017

AsthmaMap: an interactive knowledge repository for mechanisms of asthma

scientific article published on 09 December 2020

Back to the future: re-establishing guinea pig in vivo asthma models

scientific article published on 01 June 2020

Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib ⬇️

scientific article (publication date: May 2003)

Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation

scientific article published on 19 April 2014

Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle

scientific article published on 15 July 2014

Bronchial responsiveness to leukotriene D4 is resistant to inhaled fluticasone propionate

scientific article published on 30 May 2006

Challenge of isolated sputum cells supports in vivo origin of intolerance reaction to aspirin/non-steroidal anti-inflammatory drugs in asthma

scientific article published on 06 March 2012

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

scientific article published on 10 September 2015

Comparison of aerosol and intranasal challenge in a mouse model of allergic airway inflammation and hyperresponsiveness.

scientific article published on 19 May 2010

Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation

scientific article published on 19 December 2018

DNA methylation in the Neuropeptide S Receptor 1 (NPSR1) promoter in relation to asthma and environmental factors

scientific article

Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study

scientific article

Different effects of deep inspirations on central and peripheral airways in healthy and allergen-challenged mice.

scientific article published on 28 February 2008

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

scientific article

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

scientific article published in February 2010

Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes

scientific article published in October 2010

Effects of 5-lipoxygenase inhibitor zileuton on airway responses to inhaled swine house dust in healthy subjects

scientific article published on 4 June 2005

Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma

scientific article published on 22 January 2014

Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung

scientific article published in February 2008

Endothelium-dependent vascular responses induced by leukotriene B4.

scientific article published on 17 January 2007

Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100IU/ml

scientific article published on 13 November 2013

Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process

scientific article published on 07 January 2020

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

scientific article published on 27 June 2019

Exhaled volatile organic compounds as markers for medication use in asthma

scientific article published on 27 February 2020

Fixed airflow obstruction relates to eosinophil activation in asthmatics

scientific article published on 25 November 2018

Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis

scientific article published in May 2014

Food allergy-related concerns during the transition to self-management

scientific article published on 05 September 2019

Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants

scientific article published on 2 September 2017

Health-related quality of life in children and adolescents allergic to staple foods

scientific article published on 30 March 2015

Health-related quality of life, assessed with a disease-specific questionnaire, in Swedish adults suffering from well-diagnosed food allergy to staple foods

scientific article published on July 2013

High levels of urinary leukotriene E4 excretion in steroid treated patients with severe asthma

scientific article published on 01 November 2003

Higher risk of wheeze in female than male smokers. Results from the Swedish GA 2 LEN study

scientific article

Household costs associated with objectively diagnosed allergy to staple foods in children and adolescents

scientific article published on January 2015

Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69-CD56dim cells

scientific article published on 23 September 2016

Human tissue models for a human disease: what are the barriers?

scientific article published on 28 January 2015

IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

scientific article published on 02 December 2019

IL-17-high asthma with features of a psoriasis immunophenotype

scientific article published on 15 April 2019

Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma

scientific article published on 06 December 2018

Impaired health-related quality of life in adolescents with allergy to staple foods

scientific article

Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial

scientific article (publication date: 2002)

Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

scientific article published on 15 September 2015

Increased prevalence of symptoms of rhinitis but not of asthma between 1990 and 2008 in Swedish adults: comparisons of the ECRHS and GA²LEN surveys

scientific article

Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice

scientific article published on 19 January 2011

Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction

scientific article

Inhibition of nitric-oxide synthase enhances antigen-induced contractions and increases release of cysteinyl-leukotrienes in guinea pig lung parenchyma: nitric oxide as a protective factor

scientific article published on 15 July 2005

Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung

scientific article published on 3 September 2003

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

scientific article published on 12 December 2013

International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions

scientific article

International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor

scientific article (publication date: March 2004)

International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors

scientific article (publication date: March 2003)

International research collaboration: The way forward

scientific article published on 17 May 2018

Intranasal administration of poly(I:C) and LPS in BALB/c mice induces airway hyperresponsiveness and inflammation via different pathways

scientific article

Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

scientific article published on 8 May 2018

Late Breaking Abstract - Cluster analysis of treatable traits in the U-BIOPRED adult severe asthma cohort

article

Leukotriene E4 induces airflow obstruction and mast cell activation via the CysLT1 receptor

scientific article published on 5 March 2018

Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD.

scientific article published on 10 March 2016

Lipid Mediator Profiling in Pulmonary Disease ⬇️

scientific article published on July 1, 2011

Lipid Mediator Quantification in Isolated Human and Guinea Pig Airways: An Expanded Approach for Respiratory Research

scientific article published on 20 August 2018

Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids

scientific article published on 04 July 2013

Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers

scientific article published on 17 September 2018

Lipoxin A4 reduces house dust mite and TNFα-induced hyperreactivity in the mouse trachea

scientific article published on 15 February 2020

Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotection

scientific article published on 14 June 2019

Mast cell engraftment of the peripheral lung enhances airway hyperresponsiveness in a mouse asthma model ⬇️

scientific article published on 05 October 2012

Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma

scientific article published in December 2013

Mast cell mediators cause the early allergic bronchoconstriction in guinea pigs in vivo: a model of relevance to asthma

scientific article published on 14 August 2013

Modulation of antigen-induced responses by serotonin and prostaglandin E2 via EP1 and EP4 receptors in the peripheral rat lung

scientific article

No further increase of incidence of asthma: incidence, remission and relapse of adult asthma in Sweden

scientific article published on 28 August 2008

Pharmacological evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle

scientific article

Pharmacological modulation of the leukotriene pathway in allergic airway disease

scientific article published on 23 March 2007

Phenotypic predictors of response to oral glucocorticosteroids in severe asthma

scientific article published on 27 August 2013

Predicting asthma morbidity in children using proposed markers of Th2-type inflammation

scientific article published on 12 August 2015

Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model

scientific article published on 12 May 2018

Prostaglandin D2 induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig ⬇️

scientific article published on August 19, 2011

Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor

scientific article published on 9 May 2015

Prostaglandin E2 suppresses human group 2 innate lymphoid cell function.

scientific article published on 4 December 2017

Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant

scientific article published on 7 March 2010

Quality of life in relation to the traffic pollution indicators NO2 and NOx: results from the Swedish GA(2)LEN survey

scientific article

Quantification of lipid mediator metabolites in human urine from asthma patients by electrospray ionization mass spectrometry: controlling matrix effects.

scientific article

Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping

scientific article published on 06 March 2019

RNA-containing exosomes in induced sputum of asthmatic patients

scientific article published on 16 June 2017

Refractoriness to exercise challenge: a review of the mechanisms old and new.

scientific article published on 27 March 2013

Salbutamol but not ipratropium abolishes leukotriene D4-induced gas exchange abnormalities in asthma ⬇️

scientific article published on March 29, 2012

Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics

Severe asthma in adults: what are the important questions?

scientific article

Socio-economic impact of objectively-diagnosed allergy to staple foods in children and adolescents.

scientific article published on 30 March 2015

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study

Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution ⬇️

scientific article published on June 13, 2011

Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction

scientific article published on 04 June 2009

Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma

scientific article published on 07 January 2021

Sputum microbiome profiles identify severe asthma phenotypes of relative stability at 12-18 months

scientific article published on 27 April 2020

Stratification of asthma phenotypes by airway proteomic signatures

scientific article published on 28 March 2019

TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma.

scientific article

TSLP in asthma--a new kid on the block?

scientific article published on 20 May 2014

The European Respiratory Society fellowship programme: supporting young careers and building networks

scientific article published in September 2013

The European Respiratory Society spirometry tent: a unique form of screening for airway obstruction

scientific article published on 20 January 2012

The association between asthma and rhinitis is stable over time despite diverging trends in prevalence

scientific article published on 21 January 2015

The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea

scientific article published on 7 September 2012

The chitinase-like protein YKL-40: a possible biomarker of inflammation and airway remodeling in severe pediatric asthma

scientific article

The contractile action of leukotriene B4 in the guinea-pig lung involves a vascular component.

scientific article

The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release.

scientific article published in January 2002

The effect of omega-3 fatty acids on bronchial hyperresponsiveness, sputum eosinophilia, and mast cell mediators in asthma

scientific article

The influence of aspirin on release of eoxin C4, leukotriene C4 and 15-HETE, in eosinophilic granulocytes isolated from patients with asthma

scientific article

The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo

scientific article (publication date: September 2006)

The number needed to treat provides additional insight on the performance of detection points of asthma exacerbations in self-management plans: authors' response on behalf of the BIOAIR consortium

scientific article published on 22 June 2013

The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction.

scientific article published on 20 January 2011

Toll-like receptor (TLR) 7 decreases and TLR9 increases the airway responses in mice with established allergic inflammation

scientific article published on 13 September 2013

Toll-like receptor ligands LPS and poly (I:C) exacerbate airway hyperresponsiveness in a model of airway allergy in mice, independently of inflammation

scientific article

Toward clinically applicable biomarkers for asthma: An EAACI position paper

scientific article published on 01 October 2019

Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

scientific article published on 6 December 2012

Treatable Traits in the European U-BIOPRED Adult Asthma Cohorts

scientific article published on 12 November 2018

Treatment of asthma with antileukotrienes: first line or last resort therapy?

scientific article

Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites

scientific article

Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics

scientific article published on 31 August 2020

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

scientific article

Update of prevalence of self-reported allergic rhinitis and chronic nasal symptoms among adults in Sweden

scientific article published on 20 September 2011

Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7

scientific article

Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation

scientific article published on 15 July 2020

Urinary excretion of lipid mediators in response to repeated eucapnic voluntary hyperpnea in asthmatic subjects

scientific article published on 25 June 2015

Volatile Organic Compounds Breathprinting of U-BIOPRED Severe Asthma smokers/ex-smokers cohort

article

Which anti-inflammatory drug should we use in asthma?

scientific article published on 01 December 2011

Will recording of lung function fluctuation open the door to internet-guided treatment of asthma? ⬇️

scientific article published on August 19, 2011

YKL-40 is a proposed biomarker of inflammation and remodelling elevated in children with bronchopulmonary dysplasia compared to asthma

scientific article published on 08 August 2020

[Costs of asthma and allergies to society unknown. Cost studies can give better planning of health care and research]

scientific article published on 01 September 2007

[International guidelines for allergic rhinitis have been updated]

scientific article published on 01 March 2012

[Spirometry screening can identify new cases of asthma and COPD. Public lung function tests at the Stockholm's Central Station]

scientific article published on 01 June 2010

[TNF-blockade--new strategy in difficult-to-treat asthma]

scientific article published on 01 June 2008

[Wrong to discard antileukotrienes in the treatment of asthma]

scientific article published on 01 December 2007

eNose breathprints as a surrogate biomarker for classifying asthma patients by atopy

scientific article published on 09 June 2020

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