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List of works by Sebastian Bauer

5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model: preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic Oncology

scientific article published on 15 January 2022

A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor.

scientific article published on 5 October 2010

A phase II study of a human anti-PDGFRα monoclonal antibody (olaratumab, IMC-3G3) in previously treated patients with metastatic gastrointestinal stromal tumors.

scientific article published in March 2017

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE'.

scientific article published on 18 September 2017

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 ‘CREATE’

scientific article published on 01 February 2019

Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3. European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 "CREATE".

scientific article published on 5 December 2017

Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes.

scientific article published on 19 September 2011

Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial

scientific article published on 2 November 2015

Adjuvant chemotherapy for soft tissue sarcoma? a clear no - well - yes-ish

scientific article

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

scientific article published in 2024

Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial

scholarly article by Christophe Le Tourneau et al published 22 October 2018 in Journal for Immunotherapy of Cancer

Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial

scientific article published on 16 January 2019

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

scientific article published on 22 February 2019

Correlation of CTNNB1 Mutation Status with Progression Arrest Rate in RECIST Progressive Desmoid-Type Fibromatosis Treated with Imatinib: Translational Research Results from a Phase 2 Study of the German Interdisciplinary Sarcoma Group (GISG-01).

scientific article published on 9 February 2016

Covalent-Allosteric Kinase Inhibitors.

scientific article published on 25 June 2015

Cytomegalovirus induces apoptosis in acute leukemia cells as a virus-versus-leukemia function.

scientific article

DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors.

scientific article published on 10 April 2013

Desmoplastic small round cell tumors: Multimodality treatment and new risk factors

scientific article published on 16 January 2019

Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib: An Exploratory Analysis of a Randomized Clinical Trial

scientific article published on 23 March 2017

Eltrombopag for thrombocytopenia in patients with advanced solid tumors receiving gemcitabine-based chemotherapy: a randomized, placebo-controlled phase 2 study.

scientific article published in September 2017

Emerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future Directions

scientific article (publication date: August 2015)

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

scientific article published on 10 February 2016

Evaluation of 47 soft tissue sarcoma resection specimens after isolated limb perfusion with TNF-alpha and melphalan: histologically characterized improved margins correlate with absence of recurrences

scientific article published on 06 January 2009

Gastrointestinal stromal tumours (GIST)--development in pathology, surgery and medical therapy. Developed during the 10th German GIST-meeting, Göttingen

scientific article

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in October 2018

Gemcitabine in the treatment of soft tissue sarcomas.

scientific article published on April 2004

Growth patterns of lung metastases from sarcoma: prognostic and surgical implications from histology.

scientific article

Growth patterns of lung metastases from sarcomas

scientific article published on 06 July 2011

Head and Neck Kaposi Sarcoma: Clinicopathological Analysis of 11 Cases

scientific article published on 05 March 2018

Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.

scientific article published on September 2006

Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: Final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG).

scientific article published on 7 March 2017

Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.

scientific article published in September 2002

Inhibition of KIT-glycosylation by 2-deoxyglucose abrogates KIT-signaling and combination with ABT-263 synergistically induces apoptosis in gastrointestinal stromal tumor.

scientific article

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

scientific article published on 04 October 2019

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

scientific article published on 04 May 2016

Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.

scientific article

Integrative genomic and transcriptomic analysis of leiomyosarcoma.

scientific article published on 10 January 2018

Intimal sarcoma of the pulmonary artery with unusual findings: a case report

scientific article published on 24 February 2012

Isolated limb perfusion for liposarcoma : Histopathological response and subgroup analysis after TNF melphalan-based ILP

scientific article published in May 2017

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

scientific article published on 15 July 2019

Locally advanced and metastatic sarcoma (adult type) including gastrointestinal stromal tumors.

scientific article published on September 2006

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

scientific article published on 15 January 2014

Long-term outcome of dasatinib first-line treatment in gastrointestinal stromal tumor: A multicenter, 2-stage phase 2 trial (Swiss Group for Clinical Cancer Research 56/07).

scientific article published on 9 January 2018

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

scientific article

Lower limb function and quality of life after ILP for soft-tissue sarcoma

scientific article

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation.

scientific article published on 08 March 2017

Mammalian target of rapamycin pathway activity in alveolar soft part sarcoma.

scientific article published on 17 July 2013

Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments.

scientific article published on 9 May 2016

Multimodality treatment including surgery for primary pulmonary sarcoma: Size does matter

scientific article published on 14 May 2020

Needle biopsy through the abdominal wall for the diagnosis of gastrointestinal stromal tumour - Does it increase the risk for tumour cell seeding and recurrence?

scientific article published on 28 March 2016

Neoadjuvant treatment improves capsular integrity and the width of the fibrous capsule of high-grade soft-tissue sarcomas

scientific article published on 25 October 2012

One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.

scientific article

Optimal Avapritinib Treatment Strategies for Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors

scientific article published on 10 December 2020

Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing.

scientific article published on June 2005

Options for treating different soft tissue sarcoma subtypes

scientific article published on 01 May 2018

Pemetrexed in patients with refractory soft tissue sarcoma: A non-comparative multicenter phase II study of the German Sarcoma Group AIO-STS 005 ⬇️

scientific article published on July 5, 2012

Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

scientific article

Plastic Surgery in Palliative Care - Report on the Consensus Workshop of the 37th Annual Meeting of the German-language Group for Microsurgery of the Peripheral Nerves and Vessels (DAM) 2016 in Bochum

scientific article published on 29 December 2016

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.

scientific article

Postoperative FDG-PET/CT staging in GIST: Is there a benefit following R0 resection? ⬇️

scientific article published on October 22, 2010

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey.

scientific article published on 30 November 2017

Preclinical models for translational sarcoma research

scientific article

Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells

scientific article

Prognostic relevance of soluble human leukocyte antigen–G and total human leukocyte antigen class I molecules in lung cancer patients

scientific article published on 10 March 2010

Pulmonary metastasectomy for sarcoma-Essen experience.

scientific article published in October 2017

Rational promoter selection for gene transfer into cardiac cells.

scientific article published on July 2003

Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

scientific article published on 26 February 2018

Resection of residual disease in patients with metastatic gastrointestinal stromal tumors responding to treatment with imatinib.

scientific article published in November 2005

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain

scientific article published on 24 September 2020

Results for patients with sarcoma not otherwise specified and other diagnoses than Ewing sarcoma treated according to the Euro-EWING 99 trial

scientific article published on 24 April 2017

Risk factors for gastrointestinal stromal tumor recurrence in patients treated with adjuvant imatinib.

scientific article

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Somatostatin receptor scintigraphy in advanced renal cell carcinoma. Results of a phase II-trial of somatostatine analogue therapy in patients with advanced RCC.

scientific article published in January 2008

Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis.

scientific article

Survivin is a novel transcription regulator of KIT and is downregulated by miRNA-494 in gastrointestinal stromal tumors.

scientific article published on 26 December 2017

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors.

scientific article published on 20 July 2016

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

scientific article published on 30 September 2015

Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design ⬇️

scientific article published on July 10, 2013

The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15.

scientific article published on 17 February 2016

Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age ⬇️

scientific article published on 02 May 2013

Translational insights into gastrointestinal stromal tumor and current clinical advances

scientific article published on 01 October 2018

Treatment of gastrointestinal stromal tumor after imatinib and sunitinib.

scientific article published on July 2011

Tumor vascularization and histopathologic regression of soft tissue sarcomas treated with isolated limb perfusion with TNF-α and melphalan

scientific article published on 01 April 2011

[Individualized tumor therapy and status quo in melanoma].

scientific article

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