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List of works by Krisztina M Papp-Wallace

"Switching Partners": Piperacillin-Avibactam Is a Highly Potent Combination against Multidrug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli Cystic Fibrosis Isolates

scientific article published on 26 July 2019

2385. Ceftazidime–Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa

687. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Acinetobacter spp

698. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Multidrug-Resistant Gram-Negative Bacilli

698. Nacubactam Inhibits Class A β-lactamases

<i>In vitro</i> antibacterial activity and <i>in vivo</i> efficacy of sulbactam-durlobactam against pathogenic <i>Burkholderia</i> species

scientific article published on 14 December 2020

A 17-Year Nationwide Study of Burkholderia cepacia Complex Bloodstream Infections Among Patients in the United States Veterans Health Administration

scientific article published in October 2017

A Standard Numbering Scheme for Class C β-Lactamases

scientific article published on 21 February 2020

A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenems

scientific article

A γ-Lactam Siderophore Antibiotic Effective Against Multidrug-Resistant Gram-Negative Bacilli

scientific article published on 18 May 2020

AAI101, a Novel β-Lactamase Inhibitor: Microbiological and Enzymatic Profiling.

scientific article published on 4 October 2017

Activities of ceftazidime, ceftaroline, and aztreonam alone and combined with avibactam against isogenic Escherichia coli strains expressing selected single β-lactamases

scientific article published on 14 February 2015

Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV β-lactamases with single amino acid substitutions in the Ω-loop

scientific article published on 8 May 2015

Avibactam Restores the Susceptibility of Clinical Isolates of Stenotrophomonas maltophilia to Aztreonam

scientific article published on 7 August 2017

Avibactam and inhibitor-resistant SHV β-lactamases

scientific article published on 17 February 2015

Bacterial homologs of eukaryotic membrane proteins: the 2-TM-GxN family of Mg(2+) transporters

scientific article published on September 2007

Beyond Piperacillin-Tazobactam: Cefepime and AAI101 as a Potent β-Lactam-β-Lactamase Inhibitor Combination

scientific article published on 25 April 2019

Boronic Acid Transition State Inhibitors Active against KPC and Other Class A β-Lactamases: Structure-Activity Relationships as a Guide to Inhibitor Design

scientific article published on 4 January 2016

Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

scientific article

Carbapenems: past, present, and future

scientific article

Ceftazidime-Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa

scientific article published on 01 July 2019

Characterization of the AmpC β-Lactamase from Burkholderia multivorans.

scientific article published on 24 September 2018

Crystal Structures of KPC-2 β-Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226 ⬇️

scientific article published on February 13, 2012

Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa

scientific article published in 2018

Design and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-Lactamase

scientific article

Early Insights into the Interactions of Different β-Lactam Antibiotics and β-Lactamase Inhibitors against Soluble Forms of Acinetobacter baumannii PBP1a and Acinetobacter sp. PBP3 ⬇️

scientific article published on August 20, 2012

Elucidating the role of Trp105 in the KPC-2 β-lactamase

scientific article

Exploring the Landscape of Diazabicyclooctane (DBO) Inhibition: Avibactam Inactivation of PER-2 β-Lactamase

scientific article published on 27 March 2017

Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases

scientific article

Exploring the Role of the Ω-Loop in the Evolution of Ceftazidime Resistance in the PenA β-Lactamase from Burkholderia multivorans, an Important Cystic Fibrosis Pathogen

scientific article

Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems

scientific article

Exploring the role of a conserved class A residue in the Ω-Loop of KPC-2 β-lactamase: a mechanism for ceftazidime hydrolysis ⬇️

scientific article published on July 26, 2012

Exposing a β-Lactamase "Twist": the Mechanistic Basis for the High Level of Ceftazidime Resistance in the C69F Variant of the Burkholderia pseudomallei PenI β-Lactamase

scientific article published on 23 November 2015

Following drug uptake and reactions inside Escherichia coli cells by Raman microspectroscopy

scientific article

Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress

scientific article published on 21 November 2019

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone ⬇️

scientific article published on December 2, 2011

Inactivation of the Pseudomonas-Derived Cephalosporinase-3 (PDC-3) by Relebactam

scientific article published on 26 April 2018

Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study

scientific article published on 4 September 2015

Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase

scientific article

Insights into  -Lactamases from Burkholderia Species, Two Phylogenetically Related yet Distinct Resistance Determinants

scientific article

Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering

scientific article published on 31 October 2017

Magnesium Transport and Magnesium Homeostasis

scientific article published on September 2008

Manganese transport and the role of manganese in virulence

scientific article

Membrane-Bound PenA β-Lactamase of Burkholderia pseudomallei

scientific article published on 28 December 2015

Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei ⬇️

scientific article published on January 1, 2011

Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC

scientific article published on 25 July 2019

New β-Lactamase Inhibitors in the Clinic

scientific article

New β-lactamase inhibitors: a therapeutic renaissance in an MDR world

scientific article

Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae

scientific article

Novel β-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance

scientific article published on 24 December 2013

Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients

scientific article published on 6 March 2017

Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States

scientific article published on 02 July 2019

Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates

scientific article published on 28 August 2017

Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam

scientific article published on 12 February 2018

Reclaiming the efficacy of β-lactam-β-lactamase inhibitor combinations: avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime

scientific article

Regulation of CorA Mg2+ channel function affects the virulence of Salmonella enterica serovar typhimurium

scientific article published on August 2008

Relebactam is a Potent Inhibitor of the KPC-2 β-Lactamase and Restores the Susceptibility of Imipenem Against KPC-Producing Enterobacteriaceae

scientific article published on 2 April 2018

Reply to Frère: Covalent trapping and bacterial resistance to ceftazidime

scientific article published on September 2013

Resistance to Novel β-Lactam-β-Lactamase Inhibitor Combinations: The "Price of Progress"

scientific article published on 30 September 2020

Resurrecting Old β-Lactams: Potent Inhibitory Activity of Temocillin against Multidrug-Resistant Burkholderia Species Isolates from the United States

scientific article published on 27 March 2019

Sequence heterogeneity of the PenA carbapenemase in clinical isolates of Burkholderia multivorans

scientific article published on 18 June 2018

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.

scientific article published on 7 April 2018

Structural Analysis of The OXA-48 Carbapenemase Bound to A "Poor" Carbapenem Substrate, Doripenem

scientific article published on 11 September 2019

Structural Insights into the Inhibition of the Extended-Spectrum β-Lactamase PER-2 by Avibactam

scientific article published on 23 August 2019

Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum β-Lactamase and Its Inhibition by Avibactam

scientific article published on 18 March 2021

Structural insights into ceftobiprole inhibition of Pseudomonas aeruginosa penicillin-binding protein 3

scientific article published on 09 March 2020

Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors

scientific article published on 27 April 2020

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase

scientific article

Targeting Multidrug-Resistant spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent

scientific article published on 12 March 2019

The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium

scientific article published on August 2008

The Novel β-Lactamase Inhibitor, ETX-2514, in Combination with Sulbactam Effectively Inhibits Acinetobacter baumannii.

scientific article

The latest advances in β-lactam/β-lactamase inhibitor combinations for the treatment of Gram-negative bacterial infections

scientific article published on 09 September 2019

Treatment options for infections caused by carbapenem-resistant Enterobacteriaceae: can we apply "precision medicine" to antimicrobial chemotherapy?

scientific article published on 22 January 2016

Understanding the Molecular Determinants of Substrate and Inhibitor Specificities in the Carbapenemase KPC-2: Exploring the Roles of Arg220 and Glu276 ⬇️

scientific article published on June 11, 2012

Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa

scientific article

Variants of β-lactamase KPC-2 that are resistant to inhibition by avibactam

scientific article published on 9 February 2015

WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones

scientific article published on 13 March 2017

Whole Genome Sequence Analysis of Burkholderia contaminans FFH2055 Strain Reveals the Presence of Putative β-Lactamases

scientific article published on 19 February 2019

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