List of works by Andrea M Hujer

"Double carbapenem" and oral fosfomycin for the treatment of complicated urinary tract infections caused by blaNDM -harboring Enterobacteriaceae in kidney transplantation

scientific article published on 24 October 2017

"Silent" dissemination of Klebsiella pneumoniae isolates bearing K. pneumoniae carbapenemase in a long-term care facility for children and young adults in Northeast Ohio

scientific article

"Swimming in resistance": Co-colonization with carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii or Pseudomonas aeruginosa

scientific article

1348. In vitro Activity of Plazomicin, a Next-Generation Aminoglycoside, Against Carbapenemase-Producing Klebsiella pneumoniae

article published in 2018

1351. In vitro Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, Against Enterobacteriaceae With Defined Extended-Spectrum Β-Lactamases and Carbapenemases

2336. Resistance Mechanisms and Factors Associated With CTX-M-9 Group Extended-Spectrum β-Lactamase (ESBL)-Producing Enterobacteriaceae Infections in Children

article

2558. Predicting β-Lactam Resistance Using Whole Genome Sequencing (WGS) in Klebsiella pneumoniae: The Challenge of β-Lactam Inhibitors

608Can Rapid Molecular Diagnostics Assist in the Choice of b-Lactam Antibiotics? An Analysis of Data from PRIMERS-II of the Antibiotic Resistance Leadership Group (ARLG).

scientific article published in December 2014

A Nosocomial Outbreak of Extensively Drug Resistant (XDR) Acinetobacter baumannii Isolates Containing blaOXA-237 Encoded on a Plasmid

scientific article published on 11 September 2017

A Prospective Observational Study of the Epidemiology, Management, and Outcomes of Skin and Soft Tissue Infections Due to Carbapenem-Resistant Enterobacteriaceae

scientific article published on 27 July 2017

A clinical strain of Escherichia coli possessing CMY-2 plasmid-mediated amp C beta-lactamase: an emerging concern in pediatrics?

scientific article published in January 2002

A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenems

scientific article

ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates

scientific article published on October 2009

Acinetobacter baumannii isolates from pets and horses in Switzerland: molecular characterization and clinical data

scientific article

Acinetobacter baumannii rOmpA vaccine dose alters immune polarization and immunodominant epitopes

scientific article published on 12 November 2012

Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins

scientific article

Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center

scientific article

Analysis of β-Lactamase Resistance Determinants in Enterobacteriaceae from Chicago Children: a Multicenter Survey

scientific article published on 28 March 2016

Antibiotic collateral sensitivity is contingent on the repeatability of evolution

scientific article published in Nature Communications

Antibiotic resistance determinants in Acinetobacter spp and clinical outcomes in patients from a major military treatment facility

scientific article

Antibiotic resistance in the institutionalized elderly

scientific article published on June 2004

Antibody mapping of the linear epitopes of CMY-2 and SHV-1 beta-lactamases

scientific article

Application of "Precision Medicine" Through the Molecular Characterization of Extensively Drug-Resistant Klebsiella pneumoniae in a Multivisceral Transplant Patient

scientific article published on August 2017

Are Staphylococcus intermedius Infections in Humans Cases of Mistaken Identity? A Case Series and Literature Review

scientific article

Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia?

scientific article

A Multicenter Study of the Clinical and Molecular Epidemiology of TEM- and SHV-type Extended- Spectrum β-Lactamase producing (ESBL) Enterobacteriaceae (Ent) Infections in Children

scientific article published on 4 October 2017

Benefit-risk Evaluation for Diagnostics: A Framework (BED-FRAME).

scientific article

Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

scientific article

Can Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis  -Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of  -Lactam- -Lactamase Inhibitor Combinations

scientific article

Carbapenem-resistant Enterobacter cloacae isolates producing KPC-3, North Dakota, USA.

scientific article published on September 2014

Cefotaxime-resistant bacteria colonizing older people admitted to an acute care hospital

scientific article

Characterisation and clinical features of Enterobacter cloacae bloodstream infections occurring at a tertiary care university hospital in Switzerland: is cefepime adequate therapy?

scientific article

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA.

scientific article published on 20 January 2009

Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition

scientific article

Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality

scientific article published on 10 December 2016

Collateral sensitivity is contingent on the repeatability of evolution

Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii

scientific article published on 17 October 2008

Correction for Evans et al., "Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III".

scientific article published on June 2017

Culture negative empyema in a critically ill child: an opportunity for rapid molecular diagnostics

scientific article

Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa

scientific article published in 2018

Detection of SHV beta-lactamases in Gram-negative bacilli using fluorescein-labeled antibodies

scientific article

Detection of extended-spectrum β-lactamase and Klebsiella pneumoniae Carbapenemase genes directly from blood cultures by use of a nucleic acid microarray

scientific article

Development of a sensitive and specific enzyme-linked immunosorbent assay for detecting and quantifying CMY-2 and SHV beta-lactamases

scientific article published on June 2002

Emergence of Resistance to Colistin During the Treatment of Bloodstream Infection Caused by Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae.

scientific article published on 23 April 2018

Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system

scientific article published on 09 September 2009

Emergence of linezolid-resistant Staphylococcus aureus after prolonged treatment of cystic fibrosis patients in Cleveland, Ohio

scientific article

Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.

scientific article

Erratum for Wright et al., Population Structure of KPC-Producing Klebsiella pneumoniae Isolates from Midwestern U.S. Hospitals.

scientific article published in October 2014

Evaluation of Sensititre Broth Microdilution Plate for determining the susceptibility of carbapenem-resistant Klebsiella pneumoniae to polymyxins

scientific article

Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates

scientific article

Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae

scientific article

Evaluation of updated interpretative criteria for categorizing Klebsiella pneumoniae with reduced carbapenem susceptibility

scientific article

Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition

scientific article published in May 2004

Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems

scientific article

Exploring the role of a conserved class A residue in the Ω-Loop of KPC-2 β-lactamase: a mechanism for ceftazidime hydrolysis

scientific article

Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type beta-lactamases

scientific article

Extensively drug-resistant pseudomonas aeruginosa isolates containing blaVIM-2 and elements of Salmonella genomic island 2: a new genetic resistance determinant in Northeast Ohio

scientific article

Failure to Communicate: Transmission of Extensively Drug-Resistant bla OXA-237-Containing Acinetobacter baumannii-Multiple Facilities in Oregon, 2012-2014.

scientific article published on 5 September 2017

Following the Reactions of Mechanism-Based Inhibitors with β-Lactamase by Raman Crystallography ⬇️

scientific article published on November 25, 2003

Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae

scientific article

Global challenge of multidrug-resistant Acinetobacter baumannii

scientific article

Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes

scientific article

Identification of occult Fusobacterium nucleatum central nervous system infection by use of PCR-electrospray ionization mass spectrometry

scientific article

In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii

scientific article published on 13 February 2011

Increasing prevalence and dissemination of NDM-1 metallo-β-lactamase in India: data from the SMART study (2009)

scientific article

Infections caused by fluoroquinolone-resistant Escherichia coli following transrectal ultrasound-guided biopsy of the prostate

scientific article

Infections with nontyphoidal Salmonella species producing TEM-63 or a novel TEM enzyme, TEM-131, in South Africa

scientific article

Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III.

scientific article published on 26 October 2016

Inhibition of Class A β-Lactamases by Carbapenems: Crystallographic Observation of Two Conformations of Meropenem in SHV-1

scientific article

Inhibition of OXA-1 beta-lactamase by penems

scientific article

Interlaboratory reproducibility of DiversiLab rep-PCR typing and clustering of Acinetobacter baumannii isolates

scientific article

Leading Antibacterial Laboratory Research by Integrating Conventional and Innovative Approaches: The Laboratory Center of the Antibacterial Resistance Leadership Group

scientific article published on March 2017

Longitudinal analysis of the temporal evolution of Acinetobacter baumannii strains in Ohio, USA, by using rapid automated typing methods

scientific article (publication date: 2012)

Longitudinal epidemiology of multidrug-resistant (MDR) Acinetobacter species in a tertiary care hospital

scientific article published on 11 August 2011

Molecular analysis of the simultaneous production of two SHV-type extended-spectrum beta-lactamases in a clinical isolate of Enterobacter cloacae by using single-nucleotide polymorphism genotyping

scientific article published on November 2005

Multi-drug-resistant Klebsiella pneumoniae pancreatitis: a new challenge in a serious surgical infection

scientific article

Multicenter evaluation of a new DNA microarray for rapid detection of clinically relevant bla genes from beta-lactam-resistant gram-negative bacteria

scientific article

Multidrug Resistant Pseudomonas aeruginosa Causing Prosthetic Valve Endocarditis: A Genetic-Based Chronicle of Evolving Antibiotic Resistance

scientific article

Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme

scientific article published on July 2009

NDM-5 and OXA-181 Beta-Lactamases, a Significant Threat Continues To Spread in the Americas

scientific article published on May 2017

Occupational transmission of Acinetobacter baumannii from a United States serviceman wounded in Iraq to a health care worker

scientific article

Occurrence, distribution, and origins of Streptococcus pneumoniae Serotype 6C, a recently recognized serotype

scientific article published on 29 October 2008

OqxAB, a quinolone and olaquindox efflux pump, is widely distributed among multidrug-resistant Klebsiella pneumoniae isolates of human origin

scientific article published on July 2013

Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan

scientific article

Outcomes and genetic relatedness of carbapenem-resistant enterobacteriaceae at Detroit medical center

scientific article

Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae

scientific article

Penicillin sulfone inhibitors of class D beta-lactamases

scientific article

Population structure of KPC-producing Klebsiella pneumoniae isolates from midwestern U.S. hospitals

scientific article

Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

scientific article published on 21 April 2008

Pseudo-outbreak of Klebsiella oxytoca spontaneous bacterial peritonitis attributed to contamination of multidose vials of culture medium supplement

scientific article published on 23 December 2013

Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II.

scientific article

Rapid determination of quinolone resistance in Acinetobacter spp.

scientific article published on 18 March 2009

Rapid identification of bla KPC-possessing Enterobacteriaceae by PCR/electrospray ionization-mass spectrometry

scientific article published on 10 June 2010

Reply to Lesho and Clifford

scientific article published on 25 May 2016

Role of Asp104 in the SHV beta-lactamase

scientific article

SHV-type extended-spectrum beta-lactamase production is associated with Reduced cefepime susceptibility in Enterobacter cloacae

scientific article

Salvage microbiology: opportunities and challenges in the detection of bacterial pathogens following initiation of antimicrobial treatment

scientific article

Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase

scientific article published on 2 April 2007

Strategic Design of an Effective  -Lactamase Inhibitor: LN-1-255, A 6-ALKYLIDENE-2'-SUBSTITUTED PENICILLIN SULFONE

scientific article

Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates

scientific article published in December 2004

Structure-activity relationships of different beta-lactam antibiotics against a soluble form of Enterococcus faecium PBP5, a type II bacterial transpeptidase

scientific article published on February 2005

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase

scientific article

Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure

scientific article

Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition

scientific article

The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant

article

The role of OXA-1 beta-lactamase Asp(66) in the stabilization of the active-site carbamate group and in substrate turnover

scientific article published on March 2008

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme

scientific article (publication date: 18 April 2003)

Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.

scientific article published on 8 October 2003

Unexpected advanced generation cephalosporinase activity of the M69F variant of SHV beta-lactamase

scientific article published on 26 September 2002

Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa

scientific article

Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients

scientific article

Using nucleic acid microarrays to perform molecular epidemiology and detect novel β-lactamases: a snapshot of extended-spectrum β-lactamases throughout the world

scientific article

What's new in antibiotic resistance? Focus on beta-lactamases

scientific article published on June 2006

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