List of works by John Ioannidis

'Racial' differences in genetic effects for complex diseases

scientific article published on 14 November 2004

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

18F-FDG PET for evaluation of bone marrow infiltration in staging of lymphoma: a meta-analysis.

scientific article published in June 2005

18F-FDG PET for the diagnosis and grading of soft-tissue sarcoma: a meta-analysis.

scientific article published in May 2003

18F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma: a meta-analysis

scientific article published on 13 May 2008

A Comprehensive Analysis of Protocols for Deriving Dopaminergic Neurons from Human Pluripotent Stem Cells

scholarly article by Rebecca M. Marton & John Ioannidis published 10 December 2018 in Stem Cells Translational Medicine

A Genetic Marker Associated with De Quervain's Tenosynovitis

scientific article

A Genetic Marker Associated with Shoulder Dislocation.

scientific article published on 18 May 2017

A Genome-wide Association Study for Concussion Risk

scientific article published on 01 October 2020

A Universal Standard for the Validation of Blood Pressure Measuring Devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Stat

scientific article published on 31 January 2018

A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools

scientific article

A case study in model failure? COVID-19 daily deaths and ICU bed utilisation predictions in New York state

scientific article published on 11 August 2020

A comparison of bivariate, multivariate random-effects, and Poisson correlated gamma-frailty models to meta-analyze individual patient data of ordinal scale diagnostic tests

scientific article published on 10 July 2017

A compendium of genome-wide associations for cancer: critical synopsis and reappraisal

scientific article

A consensus-based transparency checklist ⬇️

scientific article published on 01 January 2020

A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility

scientific article

A generalized view of self-citation: direct, co-author, collaborative, and coercive induced self-citation

scientific article

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

scientific journal article

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

scientific article published on 16 December 2013

A heterogeneity-based genome search meta-analysis for autism-spectrum disorders

scientific article

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

scientific article

A limited number of medicines pragmatic trials had potential for waived informed consent following the 2016 CIOMS ethical guidelines

scientific article published on 15 June 2019

A list of highly influential biomedical researchers, 1996-2011.

scientific article

A manifesto for reproducible science ⬇️

scientific article (publication date: 10 January 2017)

A meta-analysis but not a systematic review: an evaluation of the Global BMI Mortality Collaboration

scientific article published on 20 April 2017

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

A meta-analysis of individual participant data constructed to align with prior expert views: comments on Bhupathiraju et al

scientific article

A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens

scientific article published on 01 January 1996

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

scientific article

A network of investigator networks in human genome epidemiology

scientific article

A nutrient-wide association study on blood pressure

scientific article

A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS.

scientific article

A road map for efficient and reliable human genome epidemiology

scientific article published on January 2006

A roadmap for successful applications of clinical proteomics

scientific article published on 27 April 2011

A simulation study of the strength of evidence in the recommendation of medications based on two trials with statistically significant results

scientific article

A standardized citation metrics author database annotated for scientific field

scientific article published on 12 August 2019

A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data

article

A systematic examination of preprint platforms for use in the medical and biomedical sciences setting

scientific article published on 28 April 2020

A systematic review of the genetic mechanisms of dolutegravir resistance

scientific article published on 01 November 2019

A test for reporting bias in trial networks: simulation and case studies

scientific article

A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Stat

scientific article

A user's guide to inflated and manipulated impact factors

scientific article published on 01 July 2019

A vision for chronic disease prevention intervention research: report from a workshop

scientific article published on 17 April 2014

A vision for the European journal of clinical investigation: note from the new editors

scientific article published on 01 January 2010

Academic criteria for appointment, promotion and rewards in medical research: where's the evidence?

scientific article published on 29 February 2016

Academic criteria for promotion and tenure in biomedical sciences faculties: cross sectional analysis of international sample of universities

scientific article published on 25 June 2020

Access to data from clinical trials in the COVID-19 crisis: open, flexible, and time-sensitive

scientific article published on 14 October 2020

Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis

scientific article

Accuracy of Smartphone Camera Applications for Detecting Atrial Fibrillation: A Systematic Review and Meta-analysis

scientific article published on 01 April 2020

Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus: an international meta-analysis

scientific article published on 01 January 2006

Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis

scientific article

Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis

scientific article

Achieving balance with power: lessons from the Balanced Anaesthesia Study

scientific article published on 20 January 2020

Acknowledging and Overcoming Nonreproducibility in Basic and Preclinical Research

scientific article published on 13 February 2017

Acute sinusitis in children: current treatment strategies

scientific article

Adherence Interventions to Improve Adherence to Antiretroviral Therapy in Low Income Settings: An Individual Patient Data Network Meta-Analysis

Adverse events in randomized trials: neglected, restricted, distorted, and silenced.

scientific article published in October 2009

Adverse events: the more you search, the more you find

scientific article published on 01 February 2006

Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study

scientific article published on 21 October 2019

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey

scientific article

Air pollution as cause of mental disease: Appraisal of the evidence

scientific article published on 20 August 2019

Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis.

scientific article published on 11 December 2004

All science should inform policy and regulation.

scientific article published on 3 May 2018

Allergens responsible for allergic contact dermatitis among children: a systematic review and meta-analysis

scientific article published on May 2011

Almost all articles on cancer prognostic markers report statistically significant results

scientific article published on 5 November 2007

Altmetric Scores, Citations, and Publication of Studies Posted as Preprints ⬇️

scientific article published in January 2018

An empirical assessment of research practices across 163 clinical trials of tumor-bearing companion dogs

scientific article published on 15 August 2019

An empirical assessment of transparency and reproducibility-related research practices in the social sciences (2014-2017)

scientific article published on 19 February 2020

An empirical assessment of validation practices for molecular classifiers

scientific article

An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses

scientific article published in March 2009

An empirical evaluation of multifarious outcomes in pharmacogenetics: beta-2 adrenoceptor gene polymorphisms in asthma treatment

scientific article published on 01 October 2006

An epidemic of false claims. Competition and conflicts of interest distort too many medical findings

scientific article

An exploratory test for an excess of significant findings

scientific article

An overview of methods for network meta-analysis using individual participant data: when do benefits arise?

scientific article

An overview of recommendations and translational milestones for genomic tests in cancer

scientific article

Anaemia in systemic lupus erythematosus: aetiological profile and the role of erythropoietin

scientific article published on March 2000

Analysis of fatality impact and seroprevalence surveys in a community sustaining a SARS-CoV-2 superspreading event

scientific article published in 2023

Anticipating consequences of sharing raw data and code and of awarding badges for sharing

scientific article

Anticonvulsants for alcohol withdrawal

scientific article

Anticonvulsants for alcohol withdrawal

scientific article (published 2005-07-20)

Antidepressants might work for people with major depression: where do we go from here?

scientific article published on 5 April 2018

Antiretroviral therapy for initial human immunodeficiency virus/AIDS treatment: critical appraisal of the evidence from over 100 randomized trials and 400 systematic reviews and meta-analyses

scientific article published on February 2014

Appendicectomies in Albanians in Greece: outcomes in a highly mobile immigrant patient population

scientific article

Application of credibility ceilings probes the robustness of meta-analyses of biomarkers and cancer risk

scientific article published on 26 November 2014

Appropriate vs clinically useful diagnostic tests

scientific article published on September 2013

Arabian nights-1001 tales of how pharmaceutical companies cater to the material needs of doctors: case report

scientific article published on December 2000

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa?

scientific article published on 14 April 2015

Are all mental disorders related to all other medical diseases and vice versa?

scientific article published on 29 January 2019

Are medical conferences useful? And for whom?

scientific article published on March 2012

Are mortality differences detected by administrative data reliable and actionable?

scientific article published in April 2013

Are randomized trials obsolete or more important than ever in the genomic era?

scientific article published on 18 April 2013

Are systematic reviews and meta-analyses still useful research? We are not sure.

scientific article published on 16 April 2018

Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies

scientific article published on 25 March 2020

Assessing Mandatory Stay-at-Home and Business Closure Effects on the Spread of COVID-19

scientific article published on 05 January 2021

Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal

scientific article

Assessing scientists for hiring, promotion, and tenure.

scientific article published on 29 March 2018

Assessing value in biomedical research: the PQRST of appraisal and reward

scientific article

Assessment of Pragmatism in Recently Published Randomized Clinical Trials

Assessment of claims of improved prediction beyond the Framingham risk score

scientific article

Assessment of cumulative evidence for the association between glutathione S-transferase polymorphisms and lung cancer: application of the Venice interim guidelines

scientific article

Assessment of cumulative evidence on genetic associations: interim guidelines

scientific article published on 26 September 2007

Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

scientific article

Assessment of systematic effects of methodological characteristics on candidate genetic associations

Assessment of transparency indicators across the biomedical literature: How open is open?

scientific article published on 01 March 2021

Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations

scientific article

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity

Association between Maternal and Infant Class I and II HLA Alleles and of Their Concordance with the Risk of Perinatal HIV Type 1 Transmission

article

Association between obesity and postoperative atrial fibrillation in patients undergoing cardiac operations: a systematic review and meta-analysis

scientific article published on 09 August 2013

Association between pediatric clinical trials and global burden of disease

scientific article published on 16 December 2013

Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis

scientific article

Association of GSTM1, GSTT1, and GSTP1 gene polymorphisms with the risk of prostate cancer: a meta-analysis

scientific article published in January 2005

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study ⬇️

scientific article published on 30 August 2011

Association of Leiden mutation in factor V gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis

scientific article published in July 2003

Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level ⬇️

scientific article

Association of collagen Ialpha 1 Sp1 polymorphism with the risk of prevalent fractures: a meta-analysis.

scientific article published on September 2001

Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis

scientific article published on 01 November 2002

Association of polymorphisms of the oestrogen receptor alpha gene with the age of menarche

scientific article published on 01 April 2002

Association of the CYP17 gene polymorphism with the risk of prostate cancer: a meta-analysis.

scientific article

Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners

scientific article published on 31 December 2009

Atherosclerosis in premenopausal women with antiphospholipid syndrome and systemic lupus erythematosus: a controlled study.

scientific article published in May 2003

Attention to local health burden and the global disparity of health research

scientific article

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

Author Correction: A consensus-based transparency checklist

scientific article published on 01 January 2020

Author Reply to: The name of the game: Is preventive screening "cancer screening?"

scientific article published on 04 March 2019

Author's Reply

scientific article (publication date: 29 November 2005)

Authors' reply to Boucher

scientific article published in the British Medical Journal

Authors' reply to Foster and colleagues

scientific article published on 24 February 2015

Authors' reply to Pérol and colleagues

scientific article published on 16 December 2016

Authors' reply to Selvapatt and colleagues, Matthews and colleagues, Badrinath, and Ward and Lee

scientific article published on 24 February 2015

Authors' reply to editorial linked to their umbrella review of meta-analyses of observational studies on type 2 diabetes and cancer

scientific article published on 11 February 2015

Autoimmune hemolytic anemia in patients with systemic lupus erythematosus

scientific article

Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial

scientific article published on 21 August 2013

Availability of large-scale evidence on specific harms from systematic reviews of randomized trials

scientific article published in October 2004

Awareness of the side effects of possessed medications in a community setting ⬇️

scientific article published on 07 March 2003

B-Cell epitope mapping of DNA topoisomerase I defines epitopes strongly associated with pulmonary fibrosis in systemic sclerosis

scientific article published on 01 March 2000

Bayes factors for superiority, non-inferiority, and equivalence designs

Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium.

scientific article published in February 2007

Benzodiazepines for alcohol withdrawal

scientific article (published 2005-01-24)

Benzodiazepines for alcohol withdrawal

scientific article

Best Practices for Data Management and Sharing in Experimental Biomedical Research

scientific article published on 7 March 2024

Better reporting of harms in randomized trials: an extension of the CONSORT statement

scientific article

Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer

scientific article

Beyond genomics: understanding exposotypes through metabolomics

scientific article

Bias in associations of emerging biomarkers with cardiovascular disease

scientific article published on April 2013

Bias in uncontrolled therapeutic trials in rheumatology due to selection of populations with extreme characteristics.

scientific article published in August 2001

Biases in obesity research: Identify, correct, endorse, or abandon effort?

scientific article

Bibliometrics: Is your most cited work your best?

scientific article published in October 2014

Biologic agents in rheumatology: unmet issues after 200 trials and $200 billion sales

scientific article published on 03 September 2013

Biomarker failures

scientific article published on 20 September 2012

Biomedical Journals and Preprint Services: Friends or Foes?

scientific article

Biomedical research: increasing value, reducing waste

scientific article

COVID-19 Antibody Seroprevalence in Santa Clara County, California

scientific article published on 17 April 2020

CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis

scientific article

CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis.

scientific article published in March 2005

Calculating additive treatment effects from multiple randomized trials provides useful estimates of combination therapies

scientific article published on 13 September 2012

Calibrating the Scientific Ecosystem Through Meta-Research

scientific article published on 02 November 2019

Calibration of credibility of agnostic genome-wide associations

scientific article published on September 2008

Call to improve transparency of trials of non-regulated interventions

scientific article published on 27 March 2015

Can Lessons Learned from Genome-Wide Research be Applied to Nutrition-Wide and Exposure-Wide Evidence?

scientific article

Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses?

scientific article

Challenges in meta-analysis of randomized clinical trials for rare harmful cardiovascular events: the case of rosiglitazone

scientific article published on 05 May 2008

Changes of serum adhesion molecules and cytokines in post-ERCP pancreatitis: adhesion molecules and cytokines in acute pancreatitis

scientific article published on 17 May 2014

Circulating autoantibodies to erythropoietin are associated with human immunodeficiency virus type 1-related anemia

scientific article published in December 1999

Citation Metrics: A Primer on How (Not) to Normalize

scientific article

Citation Patterns Following a Strongly Contradictory Replication Result: Four Case Studies From Psychology

scientific article published on 22 September 2021

Citation impact and social media visibility of Great Barrington and John Snow signatories for COVID-19 strategy

scientific article published in 2022

Citation metrics for appraising scientists: misuse, gaming and proper use

scientific article published on 04 February 2020

Citation of randomized evidence in support of guidelines of therapeutic and preventive interventions

scientific article

Claims for improved survival from systemic corticosteroids in diverse conditions: an umbrella review

scientific article published on 31 August 2011

Claims of Sex Differences

scientific article published in The Journal of the American Medical Association

Clinical Genomics: From Pathogenicity Claims to Quantitative Risk Estimates

scientific article published on 29 February 2016

Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016

scientific article published on 02 November 2020

Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient data

scientific article

Clinical interpretation and implications of whole-genome sequencing

scientific article published in March 2014

Clinical outcome prediction by microRNAs in human cancer: a systematic review

scientific article

Clinical trials in sub-Saharan Africa and established standards of care: a systematic review of HIV, tuberculosis, and malaria trials

scientific article published in July 2004

Clinical trials: A transparent future for clinical trial reporting

scientific article published on 5 May 2015

Clinical trials: what a waste

scientific article published on 10 December 2014

Clinicopathologic predictors of death and ESRD in patients with pauci-immune necrotizing glomerulonephritis

scientific article published in January 2003

Cochrane crisis: Secrecy, intolerance and evidence-based values

article

Cochrane crisis: secrecy, in tolerance, and evidence-based values ⬇️

article

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

scientific article published in The Journal of the American Medical Association

Collaborative cancer epidemiology in the 21st century: the model of cancer consortia

scientific article

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture

scientific article

Combining molecular and genetic data from different sources

scientific article

Commentary: Adjusting for bias: a user's guide to performing plastic surgery on meta-analyses of observational studies

scientific article published on 13 January 2011

Commentary: Salt and the assault of opinion on evidence.

scientific article published on 17 February 2016

Commentary: grading the credibility of molecular evidence for complex diseases

scientific article

Commentary: meta-analysis of individual participants' data in genetic epidemiology

scientific article

Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects

scientific article published in October 2006

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

scientific article

Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis

scientific article published on 18 October 2018

Comparative Evidence on Harms in Pediatric RCTs from Less Developed versus More Developed Countries Is Limited

scientific article published on 27 November 2017

Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment

scientific article published on 12 February 2013

Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study

scientific article

Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study

scientific article (publication date: October 2013)

Comparative effectiveness of medical interventions in adults versus children

scientific article published in August 2010

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.

scientific article published on 20 February 2018

Comparative rates of harms in randomized trials from more developed versus less developed countries may be different

scientific article published on 5 April 2016

Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: multiple-treatments meta-analysis

scientific article

Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses

scientific article

Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies

scientific article

Comparison of large versus smaller randomized trials for mental health-related interventions

scientific article published in March 2005

Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis

scientific article published on 30 September 2019

Comparison of myocardial fractional flow reserve and intravascular ultrasound for the assessment of slotted-tube stents

scientific article published on 01 March 2001

Comparison of pandemic excess mortality in 2020–2021 across different empirical calculations

scientific article published in 2022

Comparison of viral load and human leukocyte antigen statistical and neural network predictive models for the rate of HIV-1 disease progression across two cohorts of homosexual men.

scientific article published in February 1999

Comparisons of established risk prediction models for cardiovascular disease: systematic review

scientific article

Completeness of main outcomes across randomized trials in entire discipline: survey of chronic lung disease outcomes in preterm infants

scientific article

Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma

scientific article

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

scientific article

Concentration of the most-cited papers in the scientific literature: analysis of journal ecosystems

scientific article

Concordance of effects of medical interventions on hospital admission and readmission rates with effects on mortality

scientific article

Concordance of functional in vitro data and epidemiological associations in complex disease genetics

scientific article

Concordance of sleep and pain outcomes of diverse interventions: an umbrella review

scientific article

Conduction delay within the coronary sinus in humans: implications for atrial arrhythmias

scientific article published on 01 September 2002

Confidence and precision increase with high statistical power

scientific article published on 3 July 2013

Conflict of Interest in Nutrition Research-Reply

scientific article published on 01 July 2018

Consent insufficient for data release-Response

scientific article published on 01 May 2019

Consideration of confounding was suboptimal in the reporting of observational studies in psychiatry: a meta-epidemiological study

scientific article published on 03 December 2019

Consistency of genome-wide associations across major ancestral groups

scientific article

Content area experts as authors: helpful or harmful for systematic reviews and meta-analyses?

scientific article

Contradicted and Initially Stronger Effects in Highly Cited Clinical Research

scientific article published in 2005

Contradicted and initially stronger effects in highly cited clinical research

scientific article (publication date: 13 July 2005)

Controversy and debate on credibility ceilings. Paper 2: Using credibility ceilings to explore skepticism about observational evidence

scientific article published in November 2020

Controversy and debate on credibility ceilings. Paper 4: Credibility ceilings da capo

scientific article published in November 2020

Coronavirus disease 2019: The harms of exaggerated information and non-evidence-based measures

scientific article published on 01 April 2020

Coronavirus disease 2019: the harms of exaggerated information and non-evidence-based measures

scientific article published on 23 March 2020

Correction of phenotype misclassification based on high-discrimination genetic predictive risk models

scientific article published in November 2012

Correction to: Industry-funded versus non-profit-funded critical care research: a meta-epidemiological overview

scientific article published on 01 December 2018

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

scientific article

Correction: Multiple Citation Indicators and Their Composite across Scientific Disciplines

scientific article published on 22 August 2016

Correction: Why Most Published Research Findings Are False

scientific article published on 25 August 2022

Correlation of biochemical response to interferon alfa with histological improvement in hepatitis C: a meta-analysis of diagnostic test characteristics

scientific article published on 01 October 1997

Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials

scientific article published on 01 June 2002

Correspondence to Sand et al. “Critical Reappraisal of a Catechol-O-Methyltransferase Transversion Variant in Schizophrenia”

article by Christina M. Lill et al published April 2010 in Biological Psychiatry

Corrigendum to “A genome-wide association study identifies a common variant near the GPR22 gene as a new locus involved in prevalence and progression of osteoarthritis” [Bone. 44S2 (2009) S224]

article

Corrigendum to “STrengthening the Reporting of OBservational studies in Epidemiology — Molecular Epidemiology (STROBE-ME): An extension of the STROBE statement” [Prev. Med. 53 (2011) 377–387]

scholarly article by Valentina Gallo et al published May 2012 in Preventive Medicine

Corrigendum: Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

scientific article published on 7 July 2015

Corrigendum: Systematic reviews: guidance relevant for studies of older people

scientific article published on 2 December 2017

Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term

scientific article (published 2009-10-07)

Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term

scientific article

Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term

scientific article published on 03 August 2018

Creatine kinase-MB elevation following stent implantation

scientific article published in June 2005

Critical interpretation of Cochran's Q test depends on power and prior assumptions about heterogeneity

scientific article

Curbing Unnecessary and Wasted Diagnostic Imaging

scientific article published on 01 January 2019

Current use of routinely collected health data to complement randomized controlled trials: a meta-epidemiological survey

scientific article

Cyclophosphamide in systemic sclerosis: light and shadows

scientific article published on 01 September 2004

Cyclophosphamide with low or high dose prednisolone for systemic sclerosis lung disease.

scientific article published in February 2002

Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis

scientific article

DIETFITS study (diet intervention examining the factors interacting with treatment success) - Study design and methods

scientific article

Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics?

scientific article

Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full data sharing policy: survey of studies published in The BMJ and PLOS Medicine

scientific article published on 13 February 2018

Declaring competing interests. Types of competing interests would be of interest

Defending Biomedical Science in an Era of Threatened Funding

scientific article published on May 2017

Demystifying trial networks and network meta-analysis

scientific article published on 14 May 2013

Dental Research Waste in Design, Analysis, and Reporting: A Scoping Review

scientific article published on 15 October 2020

Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis

scientific article published on 22 October 2020

Depression prevalence using the HADS-D compared to SCID major depression classification: An individual participant data meta-analysis

scientific article published on 23 September 2020

Design and Analysis for Studying microRNAs in Human Disease: A Primer on -Omic Technologies

scientific article

Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies

scientific article published on 24 June 2014

Design and quality considerations for randomized controlled trials in systemic sclerosis

scientific article published on 01 February 2002

Design, quality, and bias in randomized controlled trials of systemic lupus erythematosus

scientific article published on May 1, 2003

Determinants of economic growth: Different time different answer?

scientific article published in March 2020

Determinants of patient recruitment in a multicenter clinical trials group: trends, seasonality and the effect of large studies

scientific article

Development of a combined database for meta-epidemiological research

scientific article

Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses

scientific article published on 1 August 2020

Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies

scientific article

Diagnosis and Treatment of Hypertension in the 2017 ACC/AHA Guidelines and in the Real World

scientific article published on 14 December 2017

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

scientific article

Diagnosis of sensorineural hearing loss with neural networks versus logistic regression modeling of distortion product otoacoustic emissions

scientific article published in March 2004

Diagnostic accuracy of the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses

scientific article

Diagnostic accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for detecting major depression in pregnant and postnatal women: protocol for a systematic review and individual patient data meta-analyses

scientific article

Diagnostic accuracy of the Geriatric Depression Scale-30, Geriatric Depression Scale-15, Geriatric Depression Scale-5 and Geriatric Depression Scale-4 for detecting major depression: protocol for a systematic review and individual participant data me

Diagnostic performance of coronary magnetic resonance angiography as compared against conventional X-ray angiography: a meta-analysis

scientific article

Diagnostic performance of intracardiac echogenic foci for Down syndrome: a meta-analysis*1 ⬇️

scientific article published on May 1, 2003

Diagnostic tests often fail to lead to changes in patient outcomes

scientific article published on 27 March 2014

Diet, body size, physical activity and risk of prostate cancer: An umbrella review of the evidence.

scientific article

Different black box warning labeling for same-class drugs

scientific article

Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes

scientific article published in The Journal of the American Medical Association

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

scientific article published in December 2004

Disclosures Can Always Be Improved-Reply

scientific article published on 01 December 2018

Disclosures in Nutrition Research: Why It Is Different

scientific article

Discontinuation of Pneumocystis carinii prophylaxis in patients infected with human immunodeficiency virus: a meta-analysis and decision analysis

scientific article published on 22 October 2001

Discovery properties of genome-wide association signals from cumulatively combined data sets

scientific article

Discussion: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false

scientific article

Dissenting Opinions in Nutrition Research-Reply

scientific article published on 01 March 2020

Distinguishing true from false positives in genomic studies: p values

scientific article

Doctors' versus patients' global assessments of treatment effectiveness: empirical survey of diverse treatments in clinical trials

scientific article published on 21 May 2008

Does evidence-based hearsay determine the use of medical treatments?

scientific article published on 6 February 2017

Does screening for disease save lives in asymptomatic adults? Systematic review of meta-analyses and randomized trials

scientific article

Does the COVID-19 pandemic provide an opportunity to eliminate the tobacco industry?

scientific article published on 23 October 2020

Double versus single stenting for coronary bifurcation lesions: a meta-analysis

scientific article published on 22 September 2009

Drivers of poor medical care

scientific article published on 6 January 2017

Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication.

scientific article published in July 2000

Dynamics of co-authorship and productivity across different fields of scientific research

scientific article published on 10 January 2018

EULAR points to consider for conducting clinical trials in systemic lupus erythematosus

scientific article published on 03 April 2008

EULAR points to consider for conducting clinical trials in systemic lupus erythematosus: literature based evidence for the selection of endpoints

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EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs

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EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics

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EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

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Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials

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Early or deferred zidovudine therapy in HIV-infected patients without an AIDS-defining illness

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Editorial: Updated guidance on human genome epidemiology (HuGE) reviews and meta-analyses of genetic associations

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Effect Sizes Reported in Highly Cited Emotion Research Compared With Larger Studies and Meta-Analyses Addressing the Same Questions

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Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: a meta-analysis

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Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial

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Effect of diastolic dysfunction on postoperative outcomes after cardiovascular surgery: A systematic review and meta-analysis

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Effect of formal statistical significance on the credibility of observational associations

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Effect of left ventricular ejection fraction and QRS duration on the survival benefit of implantable cardioverter-defibrillators: meta-analysis of primary prevention trials

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Effect of low-dose aspirin on health outcomes: An umbrella review of systematic reviews and meta-analyses

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Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time.

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Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 meta-analyses

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Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials?

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Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study

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Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection

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Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis

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Effects of different chemotherapy regimens on survival for advanced cervical cancer: systematic review and meta-analysis

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Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses

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Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups

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Efficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis

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Electrocardiogram-gated single-photon emission computed tomography versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction: a meta-analysis.

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Emergence of large treatment effects from small trials--reply

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Empirical assessment of bias in machine learning diagnostic test accuracy studies

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Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature

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Empirical evaluation of age groups and age-subgroup analyses in pediatric randomized trials and pediatric meta-analyses

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Empirical evaluation of very large treatment effects of medical interventions

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Empirical evidence for low reproducibility indicates low pre-study odds

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Endgame: engaging the tobacco industry in its own elimination

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Engaging patients and stakeholders in research proposal review: the patient-centered outcomes research institute

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Enhancing reproducibility for computational methods

scientific article published in December 2016

Enhancing the usability of systematic reviews by improving the consideration and description of interventions.

scientific article published on 20 July 2017

Ensuring the integrity of clinical practice guidelines: a tool for protecting patients

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Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses

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Environmental risk factors and interventions for obesity

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Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses

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Environmental risk factors and nonpharmacological and nonsurgical interventions for obesity: An umbrella review of meta-analyses of cohort studies and randomized controlled trials

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Epidemiologic design and analysis for proteomic studies: a primer on -omic technologies

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Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis

scientific article published on 12 July 2019

Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis - ERRATUM

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Erratum to: Methods for evaluating medical tests and biomarkers

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Erratum to: STrengthening the reporting of OBservational studies in Epidemiology—Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement

scholarly article by Valentina Gallo et al published February 2012 in European Journal of Epidemiology

Errors (my very own) and the fearful uncertainty of numbers

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Establishment of genetic associations for complex diseases is independent of early study findings

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Estimates of the continuously publishing core in the scientific workforce

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Estimating the contribution of genetic variants to difference in incidence of disease between population groups

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Ethics and Epistemology in Big Data Research

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Evaluating health system processes with randomized controlled trials

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Evaluating novel agent effects in multiple-treatments meta-regression

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Evaluation of Data Sharing After Implementation of the International Committee of Medical Journal Editors Data Sharing Statement Requirement

Evaluation of Evidence of Statistical Support and Corroboration of Subgroup Claims in Randomized Clinical Trials

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Evaluation of Wellness Determinants and Interventions by Citizen Scientists

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Evaluation of a suggested novel method to adjust BMI calculated from self-reported weight and height for measurement error

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies

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Evaluation of cluster randomized controlled trials in sub-Saharan Africa

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Evaluation of confounding in epidemiologic studies assessing alcohol consumption on the risk of ischemic heart disease

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Evaluation of excess significance bias in animal studies of neurological diseases

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Evaluation of excess statistical significance in meta-analyses of 98 biomarker associations with cancer risk.

scientific article published on 22 October 2012

Evaluation of guidelines for initiation of highly active antiretroviral therapy in a longitudinal cohort of HIV-infected individuals

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Evaluation of networks of randomized trials

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Evaluation of the association of autoantibodies with mortality in the very elderly: a cohort study

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Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease

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Evidence Based Medicine and Big Genomic Data.

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Evidence Relating Health Care Provider Burnout and Quality of Care

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Evidence Relating Health Care Provider Burnout and Quality of Care: A Systematic Review and Meta-analysis

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Evidence generation and reproducibility in cell and gene therapy research: A call to action

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Evidence of reporting biases in voxel-based morphometry (VBM) studies of psychiatric and neurological disorders

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Evidence report on the treatment of pain in cancer patients

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Evidence-based de-implementation for contradicted, unproven, and aspiring healthcare practices

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Evidence-based medicine has been hijacked: a report to David Sackett

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Evolution and translation of research findings: from bench to where?

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Evolution of Reporting P Values in the Biomedical Literature, 1990-2015.

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Evolution of treatment effects over time: empirical insight from recursive cumulative metaanalyses

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Examining the readiness of best evidence in medical education guides for integration into educational practice: A meta-synthesis

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Examining the robustness of observational associations to model, measurement and sampling uncertainty with the vibration of effects framework

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Excess Significance Bias in Repetitive Transcranial Magnetic Stimulation Literature for Neuropsychiatric Disorders

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Excess Significance Bias in the Literature on Brain Volume Abnormalities

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Exclusion of Elderly People from Randomized Clinical Trials of Drugs for Ischemic Heart Disease

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Expectant, medical, or surgical management of first-trimester miscarriage: a meta-analysis

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Expectations and challenges stemming from genome-wide association studies

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Expectations, validity, and reality in omics

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Exploration, Inference, and Prediction in Neuroscience and Biomedicine

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Exploring the geometry of treatment networks.

scientific article published in April 2008

Exposure-wide epidemiology: revisiting Bradford Hill

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Expressing death risk as condensed life experience and death intensity

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Expression of immunomodulatory genes in human monocytes induced by voriconazole in the presence of Aspergillus fumigatus

scientific article published on 18 December 2006

Extended-interval aminoglycoside administration for children: a meta-analysis

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External validation of new risk prediction models is infrequent and reveals worse prognostic discrimination

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Extrapolating from animals to humans

scientific article published in September 2012

Extreme between-study homogeneity in meta-analyses could offer useful insights

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Extremely large outlier treatment effects may be a footprint of bias in trials from less developed countries: randomized trials of gabapentinoids

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Failure to Replicate: Sound the Alarm

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Falsified papers in high-impact journals were slow to retract and indistinguishable from nonfraudulent papers

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Family History-Wide Association Study to Identify Clinical and Environmental Risk Factors for Common Chronic Diseases

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Family-based versus unrelated case-control designs for genetic associations

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Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specifications

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Fifty-year fate and impact of general medical journals

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Finding the power to reduce publication bias

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First-Trimester Ductus Venosus Screening for Cardiac Defects

First-trimester ductus venosus screening for cardiac defects: a meta-analysis

scientific article published on 14 June 2011

Flawed methods and inappropriate conclusions for health policy on overweight and obesity: the Global BMI Mortality Collaboration meta-analysis

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Footprint of publication selection bias on meta‐analyses in medicine, environmental sciences, psychology, and economics

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Forecasting for COVID-19 has failed

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Gene expression profiling for individualized breast cancer chemotherapy: success or not?

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Gene-environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta-analyses of observational studies

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Generating comparative evidence on new drugs and devices after approval

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Generic versus brand-name drugs used in cardiovascular diseases

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Genetic and molecular epidemiology

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Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis

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Genetic associations in large versus small studies: an empirical assessment

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Genetic associations: false or true? ⬇️

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Genetic effects versus bias for candidate polymorphisms in myocardial infarction: case study and overview of large-scale evidence

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Genetic predisposition to asthma and atopy

scientific article published on January 2007

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy ⬇️

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Genome-wide association studies for complex traits: consensus, uncertainty and challenges

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Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

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Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

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Genome-wide association study identifies a locus associated with rotator cuff injury

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review

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Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

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Geometry of the randomized evidence for treatments of pulmonary hypertension

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Global assessment of C-reactive protein and health-related outcomes: an umbrella review of evidence from observational studies and Mendelian randomization studies

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Global estimates of high-level brain drain and deficit

scientific article published in June 2004

Global perspective of COVID-19 epidemiology for a full-cycle pandemic

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Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial

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Greece: Crisis, smoking and tobacco conflicts in social media

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Guidelines Do Not Entangle Practitioners With Unavoidable Conflicts as Authors, and When There Is No Evidence, Just Say So

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Guidelines for cardiovascular risk assessment and cholesterol treatment--reply

scientific article published in June 2014

Guidelines for translational research in heart failure

scientific article published on 21 January 2015

Guidelines on chemotherapy in advanced stage gynecological malignancies: an evaluation of 224 professional societies and organizations

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HEGESMA: genome search meta-analysis and heterogeneity testing

scientific article published on 14 June 2005

HELOW: a program for testing extreme homogeneity in meta-analysis

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HIV lipodystrophy case definition using artificial neural network modelling.

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HIV: opportunistic infections

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HIV: prevention of opportunistic infections

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HIV: prevention of opportunistic infections

scientific article published in January 2006

HIV: prevention of opportunistic infections.

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Handling the fragile vase of scientific practices

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Hardy–Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations and power

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Harms reported by patients in rheumatology drug trials: a systematic review of randomized trials in the cochrane library from an OMERACT working group

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Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor

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Health outcomes during the 2008 financial crisis in Europe: systematic literature review

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Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes

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Heterogeneity in meta-analyses of genome-wide association investigations

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Heterogeneity of the baseline risk within patient populations of clinical trials: a proposed evaluation algorithm

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Heterogeneity testing in meta-analysis of genome searches

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Heterogeneity-based genome search meta-analysis for preeclampsia

scientific article published on 26 July 2006

Heterogeneous views on heterogeneity

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High quality of the evidence for medical and other health-related interventions was uncommon in Cochrane systematic reviews

scientific article published on 28 March 2016

Hijacked evidence-based medicine: stay the course and throw the pirates overboard

scientific article published in April 2017

Home blood pressure as a cardiovascular outcome predictor: it's time to take this method seriously

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Homeopathy can offer empirical insights on treatment effects in a null field

Homophily and co-occurrence patterns shape randomized trials agendas: illustration in antifungal agents

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How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and medication effects on systolic blood pressure

scientific article published on 18 December 2018

How good is "evidence" from clinical studies of drug effects and why might such evidence fail in the prediction of the clinical utility of drugs?

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How many contemporary medical practices are worse than doing nothing or doing less?

scientific article published on 18 July 2013

How often can meta-analyses of individual-level data individualize treatment? A meta-epidemiologic study

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How significant is sensorineural hearing loss in primary Sjögren's syndrome? An individually matched case-control study.

scientific article published in April 2001

How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation

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How to increase value and reduce waste when research priorities are set.

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How to make more published research true

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How to read a systematic review and meta-analysis and apply the results to patient care: users' guides to the medical literature

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How to survive the medical misinformation mess

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How to use a subgroup analysis: users' guide to the medical literature

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How to use an article about genetic association: A: Background concepts

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How to use an article about genetic association: B: Are the results of the study valid?

scientific article published on January 2009

How to use an article about genetic association: C: What are the results and will they help me in caring for my patients?

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How to use an article reporting a multiple treatment comparison meta-analysis.

scientific article published in September 2012

Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis.

scientific article published in October 2017

Hundreds of thousands of zombie randomised trials circulate among us

scientific article published on 30 October 2020

Hypnotic depth and postoperative death: a Bayesian perspective and an Independent Discussion of a clinical trial

Hypothesis, analysis and synthesis, it's all Greek to me

scientific article published on 20 February 2019

Identification and evaluation of risk of generalizability biases in pilot versus efficacy/effectiveness trials: a systematic review and meta-analysis

scientific article published on 11 February 2020

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

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Immunogenicity and adverse events of avian influenza A H5N1 vaccine in healthy adults: multiple-treatments meta-analysis.

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Immunogenicity and safety of the multicomponent meningococcal B vaccine (4CMenB) in children and adolescents: a systematic review and meta-analysis

scientific article published on 19 January 2018

Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors

scientific article published on 14 July 2008

Impact of Violations and Deviations in Hardy-Weinberg Equilibrium on Postulated Gene-Disease Associations

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Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study

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Impact of epidemic and individual heterogeneity on the population distribution of disease progression rates. An example from patient populations in trials of human immunodeficiency virus infection

scientific article published in December 1996

Impact of phenotype definition on genome-wide association signals: empirical evaluation in human immunodeficiency virus type 1 infection

scientific article published on 13 April 2011

Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level.

scientific article published on 6 March 2007

Impact of vaccine herd-protection effects in cost-effectiveness analyses of childhood vaccinations. A quantitative comparative analysis

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Implausible results in human nutrition research.

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Implementation of proteomic biomarkers: making it work

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Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases.

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Important drug safety information on the internet: assessing its accuracy and reliability

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Improving Disclosure of Financial Conflicts of Interest for Research on Psychosocial Interventions.

scientific article published on 11 April 2018

Improving safety reporting from randomised trials

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Improving the drug development process: more not less randomized trials

scientific article published in January 2014

Improving the integrity of published science: an expanded taxonomy of retractions and corrections

scientific article published on 25 January 2018

Improving validation practices in "omics" research

scientific article published on December 2011

In reply II-reversal of medical practices

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In the Era of Precision Medicine and Big Data, Who Is Normal?

scientific article published on 01 May 2018

Inadequacies of Physical Examination as a Cause of Medical Errors and Adverse Events: A Collection of Vignettes

scientific article published on 02 July 2015

Inconsistent Guideline Recommendations for Cardiovascular Prevention and the Debate About Zeroing in on and Zeroing LDL-C Levels With PCSK9 Inhibitors

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Increasing efficiency of preclinical research by group sequential designs

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Increasing value and reducing waste in research design, conduct, and analysis

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Independent and joint effects of the MAPT and SNCA genes in Parkinson disease

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Independent discussion sections for improving inferential reproducibility in published research

Indirect comparisons: the mesh and mess of clinical trials.

scientific article published in October 2006

Individualized cost-effectiveness analysis

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Industry involvement and baseline assumptions of cost-effectiveness analyses: diagnostic accuracy of the Papanicolaou test

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Industry sponsorship and selection of comparators in randomized clinical trials

scientific article published on 27 December 2009

Industry-funded versus non-profit-funded critical care research: a meta-epidemiological overview

scholarly article by Perrine Janiaud et al published 1 October 2018 in Intensive Care Medicine

Infection fatality rate of COVID-19 inferred from seroprevalence data

scientific article published on 14 October 2020

Inferior vena cava filters and postoperative outcomes in patients undergoing bariatric surgery: a meta-analysis

scientific article published on 18 April 2014

Inflated numbers of authors over time have not been just due to increasing research complexity

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Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials

scientific article published in September 2012

Infographic. How does exercise treatment compare with antihypertensive medications?

scientific article published on 19 December 2019

Informed consent, big data, and the oxymoron of research that is not research

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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

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Insomnia From Drug Treatments: Evidence From Meta-analyses of Randomized Trials and Concordance With Prescribing Information

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Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses

scientific article published on 04 August 2009

Intent to share Annals of Internal Medicine's trial data was not associated with data re-use

scientific article published in 2021

International collaboration, funding and association with burden of disease in randomized controlled trials in Africa

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International ranking systems for universities and institutions: a critical appraisal

scientific article published on 25 October 2007

Interpretation of epidemiologic studies very often lacked adequate consideration of confounding

scientific article published on 21 September 2017

Interpretation of research results: an indispensable mission impossible?

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Interpretation of tests of heterogeneity and bias in meta-analysis

scientific article published on October 2008

Interventions to improve cardiopulmonary resuscitation: a review of meta-analyses and future agenda

scientific article published on 07 June 2019

Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions

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Invited commentary-Genetic prediction for common diseases

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Is It Possible to Recognize a Major Scientific Discovery?

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Is everything we eat associated with cancer? A systematic cookbook review

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Is molecular profiling ready for use in clinical decision making?

scientific article published on March 2007

Is society caught up in a Death Spiral? Modeling societal demise and its reversal ⬇️

journal article from 'Frontiers in Sociology' published in 2024

Is there a glass ceiling for highly cited scientists at the top of research universities?

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Is there a glass ceiling for highly cited scientists at the top of research universities?

scientific article published in 2010

Is vitamin C superior to diltiazem for radial artery vasodilation in patients awaiting coronary artery bypass grafting?

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Is widespread screening for hepatitis C justified?

scientific article published on 13 January 2015

Isolated intraparotid Kaposi sarcoma in human immunodeficiency virus type 1 infection

scientific article published on December 2003

John Ioannidis: Uncompromising gentle maniac

scientific article published on 24 September 2015

John P. A. Ioannidis

scientific article published on 22 April 2014

Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis

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Journals should publish all "null" results and should sparingly publish "positive" results.

scientific article

Just fast keying

Khoury et al. Respond to "The Epicenter of Translational Science": Crossing All the T's

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Kinetics of antibody concentration and avidity for the assessment of immune response to pneumococcal vaccine among children with bone marrow transplants

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Knowledge Integration in Cancer: Current Landscape and Future Prospects

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Korean National Health Insurance Database--Reply

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Laboratory mouse models for the human genome-wide associations

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Lack of evidence to favor specific preventive interventions in psychosis: a network meta-analysis.

scientific article published in June 2018

Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study

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Large scale evidence and replication: insights from rheumatology and beyond ⬇️

scientific article published on 30 September 2004

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study

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Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

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Large-scale replication and heterogeneity in Parkinson disease genetic loci

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Larger effect sizes in non-randomized studies are associated with higher rates of EMA licensing approval

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Late-starter sites in randomized controlled trials

scientific article published in May 2003

Lethal news: The dexterous infiltration of news media by the tobacco industry agenda

scientific article published on 18 May 2019

Levels of absolute survival benefit for systemic therapies of advanced cancer. a call for standards

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Limitations and Misinterpretations of E-Values for Sensitivity Analyses of Observational Studies

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Limitations are not properly acknowledged in the scientific literature

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Limitations of medical research and evidence at the patient-clinician encounter scale

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Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis.

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Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature

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Long noncoding RNAs as novel predictors of survival in human cancer: a systematic review and meta-analysis

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Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome

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Lost Evidence From Registered Large Long-Unpublished Randomized Controlled Trials: A Survey

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Lowering the P Value Threshold-Reply

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METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE.

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METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.

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METRADISC-XL: a program for meta-analysis of multidimensional ranked discovery oriented datasets including microarrays

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MINIMAR (MINimum Information for Medical AI Reporting): Developing reporting standards for artificial intelligence in health care

scientific article published on 28 June 2020

Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness

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Magnitude of effects in clinical trials published in high-impact general medical journals

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Making Optimal Use of and Extending beyond Polygenic Additive Liability Models

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Making Prospective Registration of Observational Research a Reality

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Management of clinically inapparent adrenal mass

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Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies

Mapping the expanded often inappropriate use of the Framingham Risk Score in the medical literature

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Mapping the universe of registered reports

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Marginal structural models and other analyses allow multiple estimates of treatment effects in randomized clinical trials: Meta-epidemiological analysis

scientific article published in March 2019

Massive citations to misleading methods and research tools: Matthew effect, quotation error and citation copying

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Massive covidization of research citations and the citation elite

scientific article published in 2022

Materializing research promises: opportunities, priorities and conflicts in translational medicine

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Maternal cell-free viremia in the natural history of perinatal HIV-1 transmission: a meta-analysis

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Maternal viral load and rate of disease progression among vertically HIV-1-infected children: an international meta-analysis

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Measuring co-authorship and networking-adjusted scientific impact

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Media and social media attention to retracted articles according to Altmetric

scientific article published in 2021

Medical journal requirements for clinical trial data sharing: Ripe for improvement

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Medicine. Big data meets public health

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Medicine. Life cycle of translational research for medical interventions

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Mega-randomized clinical trials for blockbuster drugs--reply

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Mega-trials for blockbusters

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Meta-Analysis Comparing Established Risk Prediction Models (EuroSCORE II, STS Score, and ACEF Score) for Perioperative Mortality During Cardiac Surgery

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Meta-analyses Can Be Credible and Useful: A New Standard

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Meta-analyses identify differentially expressed micrornas in Parkinson's disease

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Meta-analyses in environmental and occupational health.

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Meta-analyses of hydroxyethyl starch for volume resuscitation

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Meta-analyses with industry involvement are massively published and report no caveats for antidepressants

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Meta-analysis comparing drug-eluting stents with bare metal stents

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Meta-analysis for ranked discovery datasets: theoretical framework and empirical demonstration for microarrays.

scientific article published on 14 September 2007

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

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Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease

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Meta-analysis in genome-wide association studies

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Meta-analysis in hematology and oncology

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Meta-analysis methods

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Meta-analysis methods for genome-wide association studies and beyond

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Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)

scientific article published on 27 November 2019

Meta-analysis of fractional flow reserve versus quantitative coronary angiography and noninvasive imaging for evaluation of myocardial ischemia

scientific article published on 20 December 2006

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

scientific article

Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass

scientific article

Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections

scientific article published on November 2001

Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections

scientific article published in November 2001

Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes

scientific article published on 01 May 2005

Meta-analysis of the association of the cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: a HuGE gene-disease association review

scientific article published on March 2004

Meta-analysis of the immunogenicity and tolerability of pandemic influenza A 2009 (H1N1) vaccines

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Meta-analysis: test performance of ultrasonography for giant-cell arteritis

scientific article published on 01 March 2005

Meta-assessment of bias in science

scientific article (publication date: 20 March 2017)

Meta-research: Evaluation and Improvement of Research Methods and Practices

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Meta-research: The art of getting it wrong

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Meta-research: Why research on research matters.

scientific article published on 13 March 2018

Meta-research: bird's eye views of primary care research

scientific article published on 19 May 2020

Metformin does not affect cancer risk: a cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial

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Methods for Evaluating Medical Tests and Biomarkers

article by Gowri Gopalakrishna et al published February 2017 in Diagnostic and Prognostic Research

Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls

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Methods to increase reproducibility in differential gene expression via meta-analysis

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Microarrays and molecular research: noise discovery?

scientific article published on 01 February 2005

Minimal and null predictive effects for the most popular blood biomarkers of cardiovascular disease

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Modeling Science Trustworthiness Under Publish Or Perish Pressure

Modeling and research on research

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Modelling of escalating outpatient antibiotic expenditures ⬇️

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Modelling science trustworthiness under publish or perish pressure

scientific article published on 10 January 2018

Modern health care as a game theory problem

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Modern health care as a game theory problem: reply

scientific article published on 01 April 2015

Molecular bias

scientific article published in January 2005

Molecular evidence-based medicine: evolution and integration of information in the genomic era.

scientific article published on May 2007

More than a billion people taking statins?: Potential implications of the new cardiovascular guidelines

scientific article published in February 2014

More time for research: Fund people not projects

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Mortality and Paclitaxel-Coated Devices: An Individual Patient Data Meta-Analysis

scientific article published on 06 May 2020

Mortality in persons with mental disorders is substantially overestimated using inpatient psychiatric diagnoses

scientific article published on 25 June 2013

Mortality in systemic sclerosis

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Mortality in systemic sclerosis: an international meta-analysis of individual patient data

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Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials ⬇️

journal article from 'Nature Communications' published in 2021

Mortality risk conferred by small elevations of creatine kinase-MB isoenzyme after percutaneous coronary intervention ⬇️

scientific article published on October 15, 2003

Most UK scientists who publish extremely highly-cited papers do not secure funding from major public and charity funders: A descriptive analysis

scientific article published on 27 February 2019

Most meta-analyses of drug interventions have narrow scopes and many focus on specific agents

scientific article published on 04 February 2013

Most psychotherapies do not really work, but those that might work should be assessed in biased studies

scientific article published on 08 March 2016

Most recommended medical interventions reach P<0.005 for their primary outcomes in meta-analyses

scientific article published on 25 November 2019

Mother-to-child transmission of HIV: developing integration of healthcare programmes with clinical, social and basic research studies. Report of the International Workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003.

scientific article published on November 2003

Multiple Citation Indicators and Their Composite across Scientific Disciplines

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Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer

scientific article published on 09 December 2008

Multivariate models of self-reported health often neglected essential candidate determinants and methodological issues

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NIH funding: The critics respond

scientific article published in January 2013

Narrow band imaging to differentiate neoplastic and non-neoplastic colorectal polyps in real time: a meta-analysis of diagnostic operating characteristics

scientific article published on 07 January 2013

Nationwide Population Science: Lessons From the Taiwan National Health Insurance Research Database

scientific article published on 20 July 2015

Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer

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Neglected tropical diseases: survey and geometry of randomised evidence

scientific article published on 22 October 2012

Neglecting Major Health Problems and Broadcasting Minor, Uncertain Issues in Lifestyle Science

scientific article published on 18 October 2019

Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis

scientific article published on 01 February 2005

Nested randomized trials in large cohorts and biobanks: studying the health effects of lifestyle factors

scientific article published in January 2008

Network geometry shows evidence sequestration for medical vs. surgical practices: treatments for basal cell carcinoma

scientific article published on 31 January 2014

Network meta-analyses performed by contracting companies and commissioned by industry

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Network meta-analysis of antidepressants - Authors' reply

scientific article published on 20 September 2018

Neurosurgical Randomized Controlled Trials-Distance Travelled

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New clinical trial designs in the era of precision medicine: An overview of definitions, strengths, weaknesses, and current use in oncology

scientific article published on 11 December 2018

New prognostic markers for outcome of acute pancreatitis: overview of reporting in 184 studies

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Next-generation systematic reviews: prospective meta-analysis, individual-level data, networks and umbrella reviews

scientific article published on 21 February 2017

Ninth international congress on peer review and scientific publication: call for research

scientific article published on 16 September 2019

Non-inferiority versus superiority trial design for new antibiotics in an era of high antimicrobial resistance: the case for post-marketing, adaptive randomised controlled trials

scientific article published on 23 August 2019

Non-publication and delayed publication of randomized trials on vaccines: survey.

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Non-randomised Ebola trials--lessons for optimal outbreak research

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Non-replication and inconsistency in the genome-wide association setting

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Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study

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Noninferiority is almost certain with lenient noninferiority margins

scientific article published on 19 November 2015

Nonrandomized studies using causal-modeling may give different answers than RCTs: a meta-epidemiological study

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Nonreproducibility of Preclinical Research-Reply

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Not-so-surprising findings.

scientific article published in July 2006

Nuchal translucency and fetal cardiac defects: a pooled analysis of major fetal echocardiography centers

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Number of published systematic reviews and global burden of disease: database analysis ⬇️

scientific article published on November 8, 2003

Nutrition and Health: Setting Realistic Expectations and Changing Research Targets

scientific article published in December 2020

Observational studies often make clinical practice recommendations: an empirical evaluation of authors' attitudes

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Obtaining evidence by a single well-powered trial or several modestly powered trials

scientific article published on 14 October 2012

Off-label prescription: experience is a gloomy lantern that does not even illuminate its bearer. Author response

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Off-label treatments were not consistently better or worse than approved drug treatments in randomized trials

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Online randomized controlled experiments at scale: lessons and extensions to medicine

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Open letter to the leader of academic medicine

scientific article published on January 2007

Opportunistic infections and HIV.

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Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling

scientific article published on 14 December 2012

Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review

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Optimal timing of coronary angiography and potential intervention in non-ST-elevation acute coronary syndromes

scientific article published on 13 August 2010

Optimal type I and type II error pairs when the available sample size is fixed

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Options for publishing research without any P-values

scientific article published on 01 August 2019

Origin and funding of the most frequently cited papers in medicine: database analysis

scientific article published on 17 March 2006

Osteomyelitis: antigranulocyte scintigraphy with 99mTC radiolabeled monoclonal antibodies for diagnosis-- meta-analysis

scientific article published on 26 September 2007

Outcome reporting bias in clinical trials: why monitoring matters

scientific article published on 14 February 2017

Overall and COVID-19-specific citation impact of highly visible COVID-19 media experts: bibliometric analysis

scientific article published in 2021

Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis

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Overinterpretation of clinical applicability in molecular diagnostic research

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Overlapping meta-analyses on the same topic: survey of published studies

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Overlapping network meta-analyses on the same topic: survey of published studies

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P values in display items are ubiquitous and almost invariably significant: A survey of top science journals.

scientific article published on 15 May 2018

PREDIMED trial of Mediterranean diet: retracted, republished, still trusted?

scientific article published on 07 February 2019

PRISMA harms checklist: improving harms reporting in systematic reviews

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Pancreatitis potentially associated drugs as a risk factor for post-endoscopic retrograde cholangiopancreatography pancreatitis: a prospective cohort study

scientific article published in May 2013

Partisan perspectives in the medical literature: a study of high frequency editorialists favoring hormone replacement therapy

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Pathways for inappropriate dispensing of antibiotics for rhinosinusitis: a randomized trial

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Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis

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Patient outcomes with teaching versus nonteaching healthcare: a systematic review

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Patient safety strategies targeted at diagnostic errors: a systematic review

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Patterns of patient enrollment in randomized controlled trials

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Pediatric versus adult drug trials for conditions with high pediatric disease burden

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Perceived information gain from randomized trials correlates with publication in high-impact factor journals

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Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients

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Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis.

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Perfect study, poor evidence: interpretation of biases preceding study design

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Perinatal transmission of human immunodeficiency virus type 1 by pregnant women with RNA virus loads <1000 copies/ml.

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Persistence of contradicted claims in the literature

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Persistent reservations against contradicted percutaneous coronary intervention indications: citation content analysis

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Personalized and longitudinal electronic informed consent in clinical trials: How to move the needle?

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Personalized genetic prediction: too limited, too expensive, or too soon?

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Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives

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Perspective: Limiting Dependence on Nonrandomized Studies and Improving Randomized Trials in Human Nutrition Research: Why and How

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Petitions in scientific argumentation: Dissecting the request to retire statistical significance

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Pharmacogenetics of the response to beta 2 agonist drugs: a systematic overview of the field

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Physical activity and cancer: an umbrella review of the literature including 22 major anatomical sites and 770 000 cancer cases

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Placing epidemiological results in the context of multiplicity and typical correlations of exposures

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Plea for routinely presenting prediction intervals in meta-analysis

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Pneumococcal aortitis in the antibiotic era

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Polymorphisms in the 5' flank of COL1A1 gene and osteoporosis: meta-analysis of published studies

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Poor performance of clinical prediction models: the harm of commonly applied methods

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Populating the Data Ark: An attempt to retrieve, preserve, and liberate data from the most highly-cited psychology and psychiatry articles ⬇️

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Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters

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Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters

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Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium

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Population-wide generalizability of genome-wide discovered associations

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Post-publication critique at top-ranked journals across scientific disciplines: a cross-sectional assessment of policies and practice

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Potential Reporting Bias in Neuroimaging Studies of Sex Differences.

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Potential increased risk of cancer from commonly used medications: an umbrella review of meta-analyses

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Potential reporting bias in fMRI studies of the brain

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Power failure: why small sample size undermines the reliability of neuroscience

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Power failure: why small sample size undermines the reliability of neuroscience

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Practices and impact of primary outcome adjustment in randomized controlled trials: meta-epidemiologic study

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Precision medicine for individual patients should use population group averages and larger, not smaller, groups

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Predicting death: an empirical evaluation of predictive tools for mortality

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Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score

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Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)-rationale and design for an international collaborative study

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Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers

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Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment ⬇️

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Predictive modeling and heterogeneity of baseline risk in meta-analysis of individual patient data

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Predictive value of viral load measurements in asymptomatic untreated HIV-1 infection: a mathematical model.

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Predictors and impact of patients lost to follow-up in a long-term randomized trial of immediate versus deferred antiretroviral treatment.

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Predictors of sustained amenorrhea from pulsed intravenous cyclophosphamide in premenopausal women with systemic lupus erythematosus

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Preoperative prediction of long-term survival after coronary artery bypass grafting in patients with low left ventricular ejection fraction.

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Preprint Servers' Policies, Submission Requirements, and Transparency in Reporting and Research Integrity Recommendations

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Preserving equipoise and performing randomized trials for COVID-19 social distancing interventions

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Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials

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Prevalence and outcomes of incidental imaging findings: umbrella review

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Prevalence and significance of race and ethnicity subgroup analyses in Cochrane intervention reviews

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Preventing tooth loss with biannual dental visits and genetic testing: does it work?

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Prevention and Management of Non-Communicable Disease: The IOC Consensus Statement, Lausanne 2013

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Prevention and control of neglected tropical diseases: overview of randomized trials, systematic reviews and meta-analyses

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Prevention and management of non-communicable disease: the IOC consensus statement, Lausanne 2013.

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Prevention and management of noncommunicable disease: the IOC Consensus Statement, Lausanne 2013.

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Primary open angle glaucoma due to T377M MYOC: Population mapping of a Greek founder mutation in Northwestern Greece

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Primary study authors of significant studies are more likely to believe that a strong association exists in a heterogeneous meta-analysis compared with methodologists

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Probability of Major Depression Classification Based on the SCID, CIDI, and MINI Diagnostic Interviews: A Synthesis of Three Individual Participant Data Meta-Analyses

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Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 p

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Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews

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Proceedings of the 4th World Conference on Research Integrity

Professional Societies Should Abstain From Authorship of Guidelines and Disease Definition Statements

scientific article published on 01 October 2018

Prognostic effect size of cardiovascular biomarkers in datasets from observational studies versus randomised trials: meta-epidemiology study

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Prognostic factors and clustering of serious clinical outcomes in antiphospholipid syndrome

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Prognostic factors and outcomes for osteosarcoma: An international collaboration

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Prognostic significance of TP53 tumor suppressor gene expression and mutations in human osteosarcoma: a meta-analysis.

scientific article published in September 2004

Prognostic significance of vascular endothelial growth factor immunohistochemical expression in head and neck squamous cell carcinoma: a meta-analysis

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Prosthesis infection: diagnosis after total joint arthroplasty with antigranulocyte scintigraphy with 99mTc-labeled monoclonal antibodies--a meta-analysis

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Protect us from poor-quality medical research

scientific article published on 01 May 2018

Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants

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Protein conjugate pneumococcal vaccines

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Public availability of published research data in high-impact journals

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Publication and other reporting biases in cognitive sciences: detection, prevalence, and prevention

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Publication delay of randomized trials on 2009 influenza A (H1N1) vaccination

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Published articles should not be dead and buried: introducing research updates

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Publishing research with P-values: Prescribe more stringent statistical significance or proscribe statistical significance?

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Quality of reporting of cancer prognostic marker studies: association with reported prognostic effect

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Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset

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Quantifying selective reporting and the Proteus phenomenon for multiple datasets with similar bias

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Quantitative synthesis in systematic reviews

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Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-Analysis of Quality of Life, Morbidity, and Mortality

scientific article published on 10 November 2015

Radiotherapy vs. nonsteroidal anti-inflammatory drugs for the prevention of heterotopic ossification after major hip procedures: a meta-analysis of randomized trials

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Randomised trials comparing chemotherapy regimens for advanced non-small cell lung cancer: biases and evolution over time

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Randomized controlled trials: Often flawed, mostly useless, clearly indispensable: A commentary on Deaton and Cartwright

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Randomized evidence on chemotherapy and hormonal therapy regimens for advanced endometrial cancer: an overview of survival data

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Randomized trial of personal genomics for preventive cardiology: design and challenges

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Randomized trials are frequently fragmented in multiple secondary publications

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Randomized trials of neurosurgical interventions: a systematic appraisal

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Ranking antidepressants.

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Raw data from clinical trials: within reach?

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Re-rethinking the article by Thombs and colleagues.

scientific article published in March 2012

Re: Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition

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Real-world effectiveness of pharmacological treatments in schizophrenia

scholarly article by Jari Tiihonen et al published March 2007 in European Psychiatry

Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic?

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Reanalyses of randomized clinical trial data

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Reanalyses of trial results--reply

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Reasons or excuses for avoiding meta-analysis in forest plots

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Recent randomized controlled trials in otolaryngology

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Recommendations and Practical Guidance for performing and reporting validation studies according to the Universal Standard for the validation of blood pressure measuring devices by the Association for the Advancement of Medical Instrumentation/Europe

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Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans

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Recommendations for biomarker identification and qualification in clinical proteomics

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Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

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Recurrent pregnancy loss and autoantibody profile in autoimmune diseases

scientific article published in December 1999

Recursive cumulative meta-analysis: a diagnostic for the evolution of total randomized evidence from group and individual patient data

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Redefine statistical significance

article by Daniel J Benjamin et al published January 2018 in Nature Human Behaviour

Redundant meta-analyses are common in genetic epidemiology

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Reforming Nutritional Epidemiologic Research-Reply

scientific article published on 01 January 2019

Registered Randomized Trials Comparing Generic and Brand-Name Drugs: A Survey

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Registering diagnostic and prognostic trials of tests: is it the right thing to do?

scientific article published on 22 May 2014

Registration practices for observational studies on ClinicalTrials.gov indicated low adherence

scientific article published on 16 September 2015

Relation between burden of disease and randomised evidence in sub-Saharan Africa: survey of research

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Relative citation impact of various study designs in the health sciences

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Remission, relapse, and re-remission of proliferative lupus nephritis treated with cyclophosphamide

scientific article published on 01 January 2000

Repeatability of published microarray gene expression analyses

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Replication and meta-analysis of TMEM132D gene variants in panic disorder

scientific article published on 4 September 2012

Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study

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Replication in Genome-Wide Association Studies

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Replication of genome-wide discovered breast cancer risk loci in the Cypriot population

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Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies

scientific article published on 17 March 2010

Replication validity of genetic association studies

scientific article (publication date: November 2001)

Replication, Duplication, and Waste in a Quarter Million Systematic Reviews and Meta-Analyses

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Reply to Badri et al. on 'Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis'.

scientific article published in August 2005

Reply to Nuijten et al.: Reanalyses actually confirm that US studies overestimate effects in softer research

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Reply to letter by Ferrante di Ruffano et al.: Patient outcomes in randomized comparisons of diagnostic tests are still the ultimate judge

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Reply to the Letter to the Editor: "Mixing Apples and Oranges in Assessing Outcomes of Repetitive Transcranial Stimulation Meta-Analyses"

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Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review

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Reporting of conflicts of interest in guidelines of preventive and therapeutic interventions

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Reporting of demographic data and representativeness in machine learning models using electronic health records

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Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment

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Reporting of systematic reviews: the challenge of genetic association studies

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Reproducibility concerns

Reproducibility in science: improving the standard for basic and preclinical research

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Reproducibility: Has Cancer Biology Failed beyond Repair?

Reproducible Research Practices and Transparency across the Biomedical Literature

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Reproducible pharmacokinetics

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Reproducible research practices and transparency in reproductive endocrinology and infertility articles

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Reproducible research practices, transparency, and open access data in the biomedical literature, 2015-2017

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Research accomplishments that are too good to be true

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Research accomplishments that are too good to be true: reply to Ting

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Research authors' reply to Barlow and Barr and Taylor-Robinson

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Research grants: Conform and be funded

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Research needs grants, funding and money--missing something?

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Research: increasing value, reducing waste - Authors' reply.

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Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification

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Response to Therapy in Antiretroviral Therapy-Naive Patients With Isolated Nonnucleoside Reverse Transcriptase Inhibitor-Associated Transmitted Drug Resistance

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Response to letter by Forike et al.: more rigorous, not less, external validation is needed

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Rethink Funding

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Retiring statistical significance would give bias a free pass

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Reversals of Established Medical Practices

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Right ventricular diastolic dysfunction in patients with anticardiolipin antibodies and antiphospholipid syndrome

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Risk and protective factors for anxiety and obsessive-compulsive disorders: an umbrella review of systematic reviews and meta-analyses

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Risk factors and interventions with statistically significant tiny effects

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Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational studies

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Risk factors for central nervous system involvement in systemic lupus erythematosus

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Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses

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Risk of myelotoxicity with intravenous cyclophosphamide in patients with systemic lupus erythematosus

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Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease

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Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis

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Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis

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SRD5A2 gene polymorphisms and the risk of prostate cancer: a meta-analysis.

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STrengthening the REporting of Genetic Association Studies (STREGA)-an extension of the STROBE statement

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STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement

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STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement

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STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement

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STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

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STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): An extension of the STROBE statement

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STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): An extension of the STROBE statement

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STrengthening the Reporting of OBservational studies in Epidemiology – Molecular Epidemiology STROBE-ME: an extension of the STROBE statement

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STrengthening the Reporting of OBservational studies in Epidemiology — Molecular Epidemiology (STROBE-ME): An extension of the STROBE statement

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STrengthening the Reporting of OBservational studies in Epidemiology — Molecular Epidemiology STROBE-ME: an extension of the STROBE statement [J Clin Epidemiol 2011;64(12):1350–1363]

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STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE Statement

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STrengthening the Reporting of OBservational studies in Epidemiology: Molecular Epidemiology STROBE-ME. An extension of the STROBE statement

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STrengthening the reporting of OBservational studies in Epidemiology—Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement

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Safety of medical interventions in children versus adults

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Safety reporting in randomized trials of mental health interventions.

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Sample size evolution in neuroimaging research: an evaluation of highly-cited studies (1990-2012) and of latest practices (2017-2018) in high-impact journals

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Science mapping analysis characterizes 235 biases in biomedical research.

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Scientific inbreeding and same-team replication: type D personality as an example

Scientific petitions and open letters in the era of covid-19

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Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement

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Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis

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Selection and presentation of imaging figures in the medical literature

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Selection in reported epidemiological risks: an empirical assessment

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Selective discussion and transparency in microarray research findings for cancer outcomes

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Selective reporting biases in cancer prognostic factor studies

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Self-reported health in high and very high incomes

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Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation.

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Seven new loci associated with age-related macular degeneration

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Sex based subgroup differences in randomized controlled trials: empirical evidence from Cochrane meta-analyses

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Sex-specific differences in effect size estimates at established complex trait loci

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Shared epitopes and rheumatoid arthritis: disease associations in Greece and meta-analysis of Mediterranean European populations

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Short-term economic impact of the Zika virus outbreak

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Shortening self-report mental health symptom measures through optimal test assembly methods: Development and validation of the Patient Health Questionnaire-Depression-4

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Should governments continue lockdown to slow the spread of covid-19?

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Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets

Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

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Single or multiple daily doses of aminoglycosides

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Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies

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Small studies are more heterogeneous than large ones: a meta-meta-analysis

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Solutions to Reduce Unnecessary Imaging-Reply

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Some main problems eroding the credibility and relevance of randomized trials

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Sources of funding for Nobel Prize-winning work: public or private?

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Spin, Bias, and Clinical Utility in Systematic Reviews of Diagnostic Studies

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Standard 6: age groups for pediatric trials

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Standardized retrieval of side effects data for meta-analysis of safety outcomes. A feasibility study in acute sinusitis

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State of the evidence: current status and prospects of meta-analysis in infectious diseases

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Statins and Multiple Noncardiovascular Outcomes

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Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) study

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Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop

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Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects

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Stealth Research and Theranos: Reflections and Update 1 Year Later

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Stealth research: Lack of peer-reviewed evidence from healthcare unicorns

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Stealth research: Lack of peer‐reviewed evidence from healthcare unicorns

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Stealth research: is biomedical innovation happening outside the peer-reviewed literature?

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Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration

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Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

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Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

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Strengthening the reporting of Genetic Risk Prediction Studies: The GRIPS statement

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Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

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Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

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Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

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Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.

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Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.

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Study design and the drug development process--reply

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Studying the elusive environment in large scale

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Suitable monitoring approaches to antiretroviral therapy in resource-poor settings: setting the research agenda

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Survival Benefits With Diverse Chemotherapy Regimens for Ovarian Cancer: Meta-analysis of Multiple Treatments

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Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis

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Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis

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Susceptibility to HIV infection--disentangling host genetics and host behavior

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Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis

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Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene).

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Synthesis of observational studies should consider credibility ceilings

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Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study

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Systematic assessment of the correlations of household income with infectious, biochemical, physiological, and environmental factors in the United States, 1999-2006

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Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey

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Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels

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Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses.

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Systematic examination of preprint platforms for use in the medical and biomedical sciences setting

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Systematic identification of correlates of HIV infection: an X-wide association study

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Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus

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Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus.

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Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

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Systematic review of the empirical evidence of study publication bias and outcome reporting bias

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Systematic reviews: guidance relevant for studies of older people

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Technical aspects and inter-laboratory variability in native peptide profiling: the CE-MS experience

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Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview

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Ten (not so) simple rules for clinical trial data-sharing

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Testing Clinical Prediction Models-Reply

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The 10-Item Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) for Functional and Cosmetic Rhinoplasty.

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The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis

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The Cancer Epidemiology Descriptive Cohort Database: A Tool to Support Population-Based Interdisciplinary Research

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The Challenge of Reforming Nutritional Epidemiologic Research

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The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs

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The Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments

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The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

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The Decameron of poor research

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The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

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The Gini coefficient as a measure for understanding accrual inequalities in multicenter clinical studies

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The Importance of Predefined Rules and Prespecified Statistical Analyses: Do Not Abandon Significance

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The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses

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The Ninth International Congress on Peer Review and Scientific Publication: A Call for Research

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The Obesity Paradox: A Misleading Term That Should Be Abandoned.

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The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations

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The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement

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The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement: Explanation and Elaboration

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The Proposal to Lower P Value Thresholds to .005.

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The Reply

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The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

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The credibility crisis in research: Can economics tools help?

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The diagnostic accuracy of the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-8 (PHQ-8), and Patient Health Questionnaire-9 (PHQ-9) for detecting major depression: protocol for a systematic review and individual patient [...]

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The role of meta-analyses and umbrella reviews in assessing the harms of psychotropic medications: beyond qualitative synthesis

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The use of older studies in meta-analyses of medical interventions: a survey.

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The value of meta-analysis in rheumatology research

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The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days

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There is nothing personal-reply

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This I believe in genetics: discovery can be a nuisance, replication is science, implementation matters

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Timing and Characteristics of Cumulative Evidence Available on Novel Therapeutic Agents Receiving Food and Drug Administration Accelerated Approval

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To Correct or Not to Correct-and How

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To replicate or not to replicate: the case of pharmacogenetic studies: Have pharmacogenomics failed, or do they just need larger-scale evidence and more replication?

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Total and cause-specific mortality before and after the onset of the Greek economic crisis: an interrupted time-series analysis

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Toward a paradigm shift in treatment and research of mental disorders

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Toward unrestricted use of public genomic data:

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Transforming Epidemiology for 21st Century Medicine and Public Health

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Translation of highly promising basic science research into clinical applications ⬇️

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Translational research may be most successful when it fails

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Transparency and reproducibility in artificial intelligence

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Transparent Communication of Radiology Research: Reporting Guidelines and Beyond

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Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration.

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Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial

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Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study

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Treatment options for acute sinusitis in children

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Trends in citations to books on epidemiological and statistical methods in the biomedical literature

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True and false positive rates for different criteria of evaluating statistical evidence from clinical trials

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Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

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Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

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Two Genetic Variants Associated with Plantar Fascial Disorders

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Two genetic loci associated with ankle injury

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Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies

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UCHL1 is a Parkinson's disease susceptibility gene

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US Food and Drug Administration Approvals of Drugs and Devices Based on Nonrandomized Clinical Trials: A Systematic Review and Meta-analysis

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US studies may overestimate effect sizes in softer research

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Unavailability of online supplementary scientific information from articles published in major journals

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Uncertainty in heterogeneity estimates in meta-analyses

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Uncontrolled pearls, controlled evidence, meta-analysis and the individual patient.

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Underlying genetic models of inheritance in established type 2 diabetes associations

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Underperforming Big Ideas in Biomedical Research-Reply

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Understanding and harnessing the health effects of rapid urbanization in China

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Undue industry influences that distort healthcare research, strategy, expenditure and practice: a review

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Unreformed nutritional epidemiology: a lamp post in the dark forest

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Unscientific beliefs about scientific topics in nutrition

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Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database

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Updated science-wide author databases of standardized citation indicators

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Use and reporting of Bland-Altman analyses in studies of self-reported versus measured weight and height

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Use of E-values for addressing confounding in observational studies-an empirical assessment of the literature

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Use of neural networks to model complex immunogenetic associations of disease: human leukocyte antigen impact on the progression of human immunodeficiency virus infection

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Use of reclassification for assessment of improved prediction: an empirical evaluation

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Using Big Data to Determine Reference Values for Laboratory Tests-Reply

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Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty

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Vaccination in adult patients with auto-immune inflammatory rheumatic diseases: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory

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Validating, augmenting and refining genome-wide association signals

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Validation and Utility Testing of Clinical Prediction Models: Time to Change the Approach

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Validation of the Greek translation of the Dundee Ready Education Environment Measure (DREEM).

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Validation protocols for blood pressure measuring devices: the impact of the European Society of Hypertension International Protocol and the development of a Universal Standard

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Very large treatment effects in randomised trials as an empirical marker to indicate whether subsequent trials are necessary: meta-epidemiological assessment

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Vibration of effects from diverse inclusion/exclusion criteria and analytical choices: 9216 different ways to perform an indirect comparison meta-analysis

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Vibration of effects in epidemiologic studies of alcohol consumption and breast cancer risk

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Viral load and response to treatment of HIV

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Visualizing the invisible: The effect of asymptomatic transmission on the outbreak dynamics of COVID-19

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Visualizing the invisible: The effect of asymptomatic transmission on the outbreak dynamics of COVID-19

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Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials

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Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: A meta-analysis

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Vitamin D receptor gene polymorphisms and risk of prostate cancer: a meta-analysis.

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Waste, Leaks, and Failures in the Biomarker Pipeline

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We need more randomized trials in nutrition-preferably large, long-term, and with negative results.

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What Other Countries Can Learn From Italy During the COVID-19 Pandemic

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What causes psychosis? An umbrella review of risk and protective factors

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What did COVID‐19 really teach us about science, evidence and society?

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What is wrong with clinical proteomics?

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What makes a good predictor?: the evidence applied to coronary artery calcium score.

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What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations

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When Null Hypothesis Significance Testing Is Unsuitable for Research: A Reassessment

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When to replicate systematic reviews of interventions: consensus checklist

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Why Cochrane should prioritise sharing data

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Why Most Discovered True Associations Are Inflated

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Why Science Is Not Necessarily Self-Correcting

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Why current publication practices may distort science

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Why most published research findings are false ⬇️

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Why replication has more scientific value than original discovery

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p-Curve and p-Hacking in Observational Research

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