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List of works by Gemma Fabrias

19F NMR analyses of some cyclopropane derivatives

3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.

scientific article published on 6 April 2012

3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.

scientific article published on March 2016

A Convenient and Stereoselective Synthesis of (3Z,5Z)-5-Fluorotetrade Cadien-1-yl Acetate, A Fluorinated Analog of the sex Pheromone of the CarpenterwormPrionoxistus robiniae(Peck)

A Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor

scientific article published on 03 January 2020

A new member of the PBAN family in Spodoptera littoralis: molecular cloning and immunovisualisation in scotophase hemolymph

scientific article published on August 2002

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.

scientific article published on 24 September 2010

Acid ceramidase as a therapeutic target in metastatic prostate cancer.

scientific article published on 19 February 2013

Action of PBAN and related peptides on pheromone biosynthesis in isolated pheromone glands of the redbanded leafroller moth, Argyrotaenia velutinana

scientific article published on 01 July 1994

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.

scientific article published on 18 August 2015

Activity-Based Imaging of Acid Ceramidase in Living Cells

scientific article published on 02 May 2019

Analogs of sex pheromone of processionary moth,Thaumetopoea pityocampa: Synthesis and biological activity

scientific article published on 01 May 1988

Anomalous formation of 1,1,4-tribromohex-1-en-3-one in the wittig reaction of 2-halopent-2-enals with dibromomethylene triphenylphosphorane

Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis.

scientific article

Azide-tagged sphingolipids: new tools for metabolic flux analysis

scientific article

C6-Ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth ⬇️

scientific article published on September 21, 2011

Cellular changes that accompany shedding of human corneocytes.

scientific article

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

scientific article

Click and count: specific detection of acid ceramidase activity in live cells

scientific article published in 2020

Comparative sex pherome biosynthesis in Thaumetopoea pityocampa and T. processionea: a rationale for the phenotypic variation in the sex pherome within the genus Thaumetopoea

scientific article published on February 2003

Control of the biosynthetic pathway of Sesamia nonagrioides sex pheromone by the pheromone biosynthesis activating neuropeptide

scientific article published on June 2000

Coordinated regulation of the orosomucoid-like gene family expression controls de novo ceramide synthesis in mammalian cells.

scientific article published on 17 December 2014

De novo ceramide synthesis is involved in acute inflammation during labor

scientific article published on 01 January 2016

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

scientific article published on 16 September 2016

Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms.

scientific article published on 25 November 2016

Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains

article

Effect of prenatal steroidal inhibition of sPLA2 in a rat model of preterm lung.

scientific article published on 15 December 2015

Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis

scientific journal article

Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis ⬇️

scientific article published on April 2, 2012

Fluorinated analogs of insect sex pheromones

article by F. Camps et al published September 1984 in Cellular and Molecular Life Sciences

From the configurational preference of dihydroceramide desaturase-1 towards Δ6-unsaturated substrates to the discovery of a new inhibitor.

scientific article

Identification and biosynthesis of (E,E)-10,12-tetradecadienyl acetate in Spodoptera littoralis female sex pheromone gland

scientific article published on July 1997

Inhibition of acid ceramidase by a 2‐substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N‐(4‐hydroxyphenyl) retinamide ⬇️

scientific article published on December 28, 2010

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.

scientific article published on 29 May 2014

Introduction to the special issue: Inhibitors of enzymes involved in lipid metabolism

scientific article published on 17 August 2015

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile

scientific article

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

scientific article

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: new insights into the pathogenesis of Krabbe's disease

scientific article published on 24 January 2014

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis

scientific article published on 2 November 2015

Natural grape extracts regulate colon cancer cells malignancy.

scientific article

Natural products as platforms for the design of sphingolipid-related anticancer agents

scientific article published on January 2013

New fluorogenic probes for neutral and alkaline ceramidases

scientific article published on 29 March 2019

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna

scientific article published on 24 March 2015

On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.

scientific article

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1

scientific article

Sila-pheromones: Silicon analogues of the female sex pheromone of the processionary moth thaumetopoea pityocampa

article by Gemma Arsequell et al published January 1990 in Tetrahedron Letters

Specific sphingolipid content decrease in Cerkl knockdown mouse retinas

scientific journal article

Stereospecificity of the (Z)-9 desaturase that converts (E)-11-tetradecenoic acid into (Z,E)-9,11-tetradecadienoic acid in the biosynthesis of Spodoptera littoralis sex pheromone

scientific article published on June 2001

Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.

scientific article published on 30 May 2013

Synthesis of [14,14,14-2H3] 12-hydroxytetradecanoic acid and [13,14-2H2] 11-hydroxytetradecanoic acid useful as tracers to study a (11E)-desaturation reaction in Spodoptera littoralis

scientific article published on March 1996

Synthesis of a fluorinated analog of the sex pheromone of the processionary moth thaumetopoea. pityocampa(denis and schiff.)

article by Francisco Camps et al published January 1986 in Tetrahedron

Synthesis of dienic fluorinated analogs of insect sex pheromones

article by Francisco Camps et al published January 1984 in Tetrahedron

Synthesis of gem-Dideuterated Tetradecanoic Acids and Their Use in Investigating the Enzymatic Transformation of (Z)-11-Tetradecenoic Acid into (E,E)-10,12-Tetradecadienoic Acid ⬇️

scientific article published on November 30, 2001

Systemic ceramide accumulation leads to severe and varied pathological consequences.

scientific article published on 16 May 2013

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

scientific article published on 13 May 2020

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells

scientific article published in May 2017

Thiafatty acids as tracers to investigate biosynthetic pathways of lepidopteran sex pheromones

scientific article

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions

scientific article

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