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List of works by John E. Casida

5-Azidoepibatidine: an exceptionally potent photoaffinity ligand for neuronal alpha 4 beta 2 and alpha 7 nicotinic acetylcholine receptors

scientific article

6'-Methylpyrido[3,4-b]norhomotropane: synthesis and outstanding potency in relation to the alpha4beta2 nicotinic receptor pharmacophore model

scientific article

A brain detoxifying enzyme for organophosphorus nerve poisons

scientific article

Activation of the endocannabinoid system by organophosphorus nerve agents

scientific article

Activity-Based Protein Profiling of Organophosphorus and Thiocarbamate Pesticides Reveals Multiple Serine Hydrolase Targets in Mouse Brain ⬇️

scientific article published on July 21, 2010

Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes

scientific article published in 2011

Acute toxicity, bioconcentration, elimination and antioxidant effects of fluralaner in zebrafish, Danio rerio

scientific article published on 15 September 2017

Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease ⬇️

scientific article published on December 24, 2012

Aldehyde oxidase importance in vivo in xenobiotic metabolism: imidacloprid nitroreduction in mice

scientific article

Alpha-nitro ketone as an electrophile and nucleophile: synthesis of 3-substituted 2-nitromethylenetetrahydrothiophene and -tetrahydrofuran as drosophila nicotinic receptor probes

scientific article published in February 2004

Anticholinesterase insecticide retrospective ⬇️

scientific article published on August 16, 2012

Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors

scientific article published in October 2003

Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore

scientific article

Atypical nicotinic agonist bound conformations conferring subtype selectivity

scholarly article

Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease

scientific article

Bis-neonicotinoid insecticides: Observed and predicted binding interactions with the nicotinic receptor.

scientific article published on 9 May 2009

Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants

scientific article

Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides

scientific article published in September 2002

Cartap hydrolysis relative to its action at the insect nicotinic channel

scientific article

Cellular function of neuropathy target esterase in lysophosphatidylcholine action

scientific article published on 25 July 2008

Characterization of the transient oxaphosphetane BChE inhibitor formed from spontaneously activated ethephon

scientific article published on 13 August 2013

Chloropyridinyl neonicotinoid insecticides: diverse molecular substituents contribute to facile metabolism in mice.

scientific article published in July 2006

Chlorpyrifos Oxon Potentiates Diacylglycerol-Induced Extracellular Signal-Regulated Kinase (ERK 44/42) Activation, Possibly by Diacylglycerol Lipase Inhibition ⬇️

scientific article published on January 1, 2002

Cloning, expression, and catalytic triad of recombinant arylformamidase

scientific article published in November 2005

Comparative metabolism and pharmacokinetics of seven neonicotinoid insecticides in spinach

scientific article

Complete spectral assignments of cevadine and veratridine by 2D NMR techniques

Curious about pesticide action

scientific article published on 11 August 2010

Cycloxaprid insecticide: nicotinic acetylcholine receptor binding site and metabolism

scientific article published on 7 August 2013

Defining nicotinic agonist binding surfaces through photoaffinity labeling

scientific article published on 06 July 2007

Desnitro-imidacloprid activates the extracellular signal-regulated kinase cascade via the nicotinic receptor and intracellular calcium mobilization in N1E-115 cells

scientific article published in November 2002

Diamide insecticide target site specificity in the Heliothis and Musca ryanodine receptors relative to toxicity

scientific article published on 24 April 2014

Drosophila nicotinic receptors: evidence for imidacloprid insecticide and alpha-bungarotoxin binding to distinct sites

scientific article published in November 2004

Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification

scientific article published on 3 December 2007

Each lipase has a unique sensitivity profile for organophosphorus inhibitors

scientific article

Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype

scientific journal article

Enzymes and inhibitors in neonicotinoid insecticide metabolism

scientific article published on June 2009

Evidence that mouse brain neuropathy target esterase is a lysophospholipase

scientific article

Fiprole insecticide resistance of Laodelphax striatellus: electrophysiological and molecular docking characterization of A2'N RDL GABA receptors

scientific article published on 04 July 2018

Fluorescent probes for insect ryanodine receptors: candidate anthranilic diamides.

scientific article published on 2 April 2014

GABA receptor antagonists and insecticides: common structural features of 4-alkyl-1-phenylpyrazoles and 4-alkyl-1-phenyltrioxabicyclooctanes

scientific article

GABAA receptor open-state conformation determines non-competitive antagonist binding ⬇️

scientific article published on November 25, 2010

GABAA receptor target of tetramethylenedisulfotetramine

scientific article

Glufosinate binds N-methyl-D-aspartate receptors and increases neuronal network activity in vitro

scientific article published on 28 September 2014

Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives

scientific article published on 21 July 2007

Golden age of RyR and GABA-R diamide and isoxazoline insecticides: common genesis, serendipity, surprises, selectivity, and safety

scientific article published on 26 February 2015

Identification of aldehyde oxidase as the neonicotinoid nitroreductase

scientific article

Imidacloprid insecticide metabolism: human cytochrome P450 isozymes differ in selectivity for imidazolidine oxidation versus nitroimine reduction

scientific article published in June 2002

Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists

scientific article published on 24 February 2007

Insect nicotinic acetylcholine receptors: neonicotinoid binding site specificity is usually but not always conserved with varied substituents and species

scientific article published in May 2006

Insect nicotinic receptor interactions in vivo with neonicotinoid, organophosphorus, and methylcarbamate insecticides and a synergist

scientific article published on 09 October 2013

Insect ryanodine receptor: distinct but coupled insecticide binding sites for [N-C(3)H(3)]chlorantraniliprole, flubendiamide, and [(3)H]ryanodine

scientific article

Insect γ-aminobutyric acid receptors and isoxazoline insecticides: toxicological profiles relative to the binding sites of [³H]fluralaner, [³H]-4'-ethynyl-4-n-propylbicycloorthobenzoate, and [³H]avermectin

scientific article

Insecticidal activity of various 3-acyl and other derivatives of veracevine relative to the veratrum alkaloids veratridine and cevadine

scholarly article by Istvan Ujvary et al published October 1991 in Journal of Agricultural and Food Chemistry

Insecticides in Chinese Medicinal Plants: Survey Leading to Jacaranone, A Neurotoxicant and Glutathione-Reactive Quinol ⬇️

scientific article published on April 23, 2003

Interaction of Imidacloprid Metabolites and Analogs with the Nicotinic Acetylcholine Receptor of Mouse Brain in Relation to Toxicity

article

Kynurenine formamidase: determination of primary structure and modeling-based prediction of tertiary structure and catalytic triad

scientific journal article

Lipases and their inhibitors in health and disease

scientific article published on 8 April 2016

Liquid chromatography-tandem mass spectrometric ion-switching determination of chlorantraniliprole and flubendiamide in fruits and vegetables

scientific article published on 9 August 2008

Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity

scientific article (publication date: April 2003)

Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes, and brain: sensitive targets of conserved specificity for organophosphorus delayed neurotoxicants

scientific article

Lysophospholipase inhibition by organophosphorus toxicants

scientific article published in May 2004

Major intermediates in organophosphate synthesis (PCl3, POCl3, PSCl3, and their diethyl esters) are anticholinesterase agents directly or on activation

scientific article published in March 2003

Mapping the elusive neonicotinoid binding site

scholarly article

Melatonin reduces phosphine-induced lipid and DNA oxidation in vitro and in vivo in rat brain

scientific article published in January 2002

Michael Elliott's billion dollar crystals and other discoveries in insecticide chemistry

scientific article

Molecular features of neonicotinoid pharmacophore variants interacting with the insect nicotinic receptor

scientific article published in March 2009

Molecular recognition of neonicotinoid insecticides: the determinants of life or death

scientific article published on February 2009

Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice

scientific article published on 28 November 2005

Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels

scientific article published on 06 August 2008

Neo-nicotinoid metabolic activation and inactivation established with coupled nicotinic receptor-CYP3A4 and -aldehyde oxidase systems.

scientific article published on 8 September 2005

Neonicotinoid Insecticides: Highlights of a Symposium on Strategic Molecular Designs ⬇️

scientific article published on November 15, 2010

Neonicotinoid Metabolism: Compounds, Substituents, Pathways, Enzymes, Organisms, and Relevance ⬇️

scientific article published on August 23, 2010

Neonicotinoid formaldehyde generators: Possible mechanism of mouse-specific hepatotoxicity/hepatocarcinogenicity of thiamethoxam ⬇️

scientific article published on December 7, 2012

Neonicotinoid insecticide toxicology: mechanisms of selective action

scientific article (publication date: 2005)

Neonicotinoid insecticides induce salicylate-associated plant defense responses.

scientific article

Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition

scientific article published on 15 April 2011

Neonicotinoid insecticides: reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes

scientific article published in September 2002

Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives

scientific article published in September 2005

Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor

scientific article published in March 2009

Neonicotinoids and Other Insect Nicotinic Receptor Competitive Modulators: Progress and Prospects

scientific article published in January 2018

Nereistoxin and Cartap Neurotoxicity Attributable to Direct Block of the Insect Nicotinic Receptor/Channel ⬇️

scientific article published on April 23, 2003

Neuroactive insecticides: targets, selectivity, resistance, and secondary effects

scientific article

New GABA/glutamate receptor target for [³H]isoxazoline insecticide

scientific article published on 12 March 2013

Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor

scientific article published on March 2013

Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling

scientific article published on June 2009

Nitroso-imidacloprid irreversibly inhibits rabbit aldehyde oxidase

scientific article

Novel Bioactive Cubé Insecticide Constituents: Isolation and Preparation of 13-homo-13-Oxa-6a,12a-dehydrorotenoids ⬇️

scientific article published on January 24, 1997

Novel GABA receptor pesticide targets

scientific article

Novel irreversible butyrylcholinesterase inhibitors: 2-chloro-1-(substituted-phenyl)ethylphosphonic acids

scientific article published in May 2002

Novel nicotinic action of the sulfoximine insecticide sulfoxaflor ⬇️

scientific article published on February 4, 2011

Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets

scientific article published in August 2004

Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids

scientific article

Organophosphorus Xenobiotic Toxicology

scientific article published on January 2017

Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins

scientific article

Pest toxicology: the primary mechanisms of pesticide action

scientific article published on April 2009

Pesticide Chemical Research in Toxicology: Lessons from Nature

scientific article

Pesticide Detox by Design

scientific article published on 31 August 2018

Pesticide Interactions: Mechanisms, Benefits, and Risks.

scientific article

Pharmacological profiles of recombinant and native insect nicotinic acetylcholine receptors

scientific article published on 15 September 2005

Phenylpyrazole Insecticide Photochemistry, Metabolism, and GABAergic Action: Ethiprole Compared with Fipronil ⬇️

scientific article published on November 19, 2003

Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates

scientific article published on 11 November 2004

Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche

scientific article

Radioligand Recognition of Insecticide Targets.

scientific article published on 9 March 2018

Receptor structure-guided neonicotinoid design

scientific article published on 27 September 2010

Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease

scientific article

Ryanodine receptor genes of the rice stem borer, Chilo suppressalis: Molecular cloning, alternative splicing and expression profiling

scientific article published on 8 June 2016

S-Arachidonoyl-2-thioglycerol synthesis and use for fluorimetric and colorimetric assays of monoacylglycerol lipase

scientific article published on 18 January 2010

Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: toxicological implications

scientific article published in February 2002

Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptors

scientific article (publication date: 2003)

Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions

scientific article published on September 2006

Serine hydrolase targets of organophosphorus toxicants

scientific article

Species differences in chlorantraniliprole and flubendiamide insecticide binding sites in the ryanodine receptor

scientific article published on 27 September 2013

Specificity of ethephon as a butyrylcholinesterase inhibitor and phosphorylating agent

scientific article published in December 2002

Spontaneous mobility of GABAA receptor M2 extracellular half relative to noncompetitive antagonist action

scientific article published on 18 October 2006

Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors

scientific article

Structural model for gamma-aminobutyric acid receptor noncompetitive antagonist binding: widely diverse structures fit the same site

scholarly article

Substrate specificity of rabbit aldehyde oxidase for nitroguanidine and nitromethylene neonicotinoid insecticides

scientific article published on January 2006

Synthesis of a Tritium-Labeled, Fipronil-Based, Highly Potent, Photoaffinity Probe for the GABA Receptor ⬇️

scientific article published on October 17, 2003

The ABCs of pesticide toxicology: amounts, biology, and chemistry

scientific article published on 22 August 2017

The Greening of Pesticide–Environment Interactions: Some Personal Observations ⬇️

scientific article published on January 18, 2012

The neonicotinoid electronegative pharmacophore plays the crucial role in the high affinity and selectivity for the Drosophila nicotinic receptor: an anomaly for the nicotinoid cation--pi interaction model

scientific article

Toxicological and structural features of organophosphorus and organosulfur cannabinoid CB1 receptor ligands

scientific article published on 27 August 2003

Unexpected Metabolic Reactions and Secondary Targets of Pesticide Action

scientific article published on 18 May 2016

Unique Neonicotinoid Binding Conformations Conferring Selective Receptor Interactions ⬇️

scientific article published on July 15, 2010

Unique and common metabolites of thiamethoxam, clothianidin, and dinotefuran in mice

scientific article published in November 2006

Unique insecticide specificity of human homomeric rho 1 GABA(C) receptor

scientific article published in March 2002

Why Prodrugs and Propesticides Succeed

scientific article published on 23 March 2017

Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.

scientific article published on 25 September 2008

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