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List of works by John Wahren

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A dye dilution method for the determination of brachial artery blood flow during rhythmic exercise

scientific article published in January 1967

A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans ⬇️

scientific article published on July 1, 1995

A versatile technique for multichannel, digital blood temperature recording in man.

scientific article

Amino Acid Metabolism in McArdle's Syndrome ⬇️

scientific article published on April 12, 1973

Amino acid metabolism during prolonged starvation

scientific article published on March 1969

Amino acid metabolism in exercising man ⬇️

scientific article published on December 1, 1971

Amino acids in liver disease ⬇️

scientific article published on September 1, 1983

Augmented thermic effect of amino acids under general anaesthesia: a mechanism useful for prevention of anaesthesia-induced hypothermia

scientific article published in May 1994

Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with Type 1 diabetes mellitus

scientific article

Brain Substrate Utilization during Prolonged Exercise ⬇️

scientific article published on January 1, 1972

Brain substrate utilisation during acute hypoglycaemia

scientific article

Branched-chain amino acids in the treatment of chronic hepatic encephalopathy

scientific article

C-Peptide is Relevant in Type 1 Diabetes and its Complications: Summary and Conclusions to the Special Issue

scientific article

C-Peptide: the missing link in diabetic nephropathy?

scientific article

C-peptide and its C-terminal fragments improve erythrocyte deformability in type 1 diabetes patients

scientific article

C-peptide and long-term complications of diabetes ⬇️

scientific article published on 05 December 2010

C-peptide binding to human cell membranes: importance of Glu27.

scientific article published in June 2001

C-peptide exerts beneficial effects on myocardial blood flow and function in patients with type 1 diabetes

scientific article published in October 2002

C-peptide fragments stimulate glucose utilization in diabetic rats

scientific article published in March 2004

C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients

scientific article published on 3 September 2003

C-peptide improves neuropathy in type 1 diabetic BB/Wor-rats

scientific article published in January 2007

C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

scientific article

C-peptide increases forearm blood flow in patients with type 1 diabetes via a nitric oxide-dependent mechanism

scientific article

C-peptide is a bioactive peptide

scientific article

C-peptide makes a comeback

scientific article published in September 2003

C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat.

scientific article

C-peptide prevents glomerular hypertrophy and mesangial matrix expansion in diabetic rats

scientific article

C-peptide revisited--new physiological effects and therapeutic implications

scientific article published on September 1996

C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells

scientific article published on 29 December 2004

C-peptide: a new potential in the treatment of diabetic nephropathy

scientific article

C-peptide: new findings and therapeutic implications in diabetes

scientific article

C-peptide: new findings and therapeutic possibilities

scientific article

Can C‐peptide mediated anti‐inflammatory effects retard the development of microvascular complications of type 1 diabetes? ⬇️

scientific article published on July 1, 2013

Cellular internalization of proinsulin C-peptide

scientific article published on February 2007

Cerebral effects of nicotine during cognition in smokers and non-smokers ⬇️

scientific article published on March 1, 1998

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

scientific article

Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting

scientific article published in February 1999

Contributions of gluconeogenesis to glucose production in the fasted state

scientific article published on July 1996

Degradation of proinsulin C-peptide in kidney and placenta extracts by a specific endoprotease activity

scientific article published in December 2004

Diet-induced thermogenesis in patients with liver cirrhosis.

scientific article

Diet-induced thermogenesis in well-trained subjects

scientific article

Diminished skin blood flow in Type I diabetes: evidence for non-endothelium-dependent dysfunction

scientific article

Direct measurements of the permeability surface area for insulin and glucose in human skeletal muscle

scientific article published in October 2003

Does C-peptide have a physiological role?

scientific article published on September 1994

Early microvascular dysfunction in healthy normal-weight males with heredity for type 2 diabetes

scientific article published in June 2005

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes

scientific article published in September 1994

Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus ⬇️

scientific article published on April 1, 1976

Effects of C-peptide on blood flow, capillary diffusion capacity and glucose utilization in the exercising forearm of type 1 (insulin-dependent) diabetic patients

scientific article published on December 1, 1992

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

scientific article

Effects of nutrition and diabetes mellitus on the regulation of metabolic fuels during exercise

scientific article published on May 1989

Effects of pancreas transplantation on metabolic and hormonal profiles in IDDM patients

scientific article published in January 1989

Effects of proinsulin C-peptide in experimental diabetic neuropathy: vascular actions and modulation by nitric oxide synthase inhibition

scientific article

Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na+,K+-ATPase activity in diabetes mellitus type I.

scientific article

Efficacy of a long-acting C-peptide analogue against peripheral neuropathy in streptozotocin-diabetic mice

scientific article published on 23 April 2015

Enhanced insulin action following subcutaneous co-administration of insulin and C-peptide in rats

scientific article published on February 2014

Ernst-Friedrich-Pfeiffer Memorial Lecture. New aspects of C-peptide physiology

scientific article published in January 1998

Estimates of Krebs cycle activity and contributions of gluconeogenesis to hepatic glucose production in fasting healthy subjects and IDDM patients

scientific article

Evanescent effects of hypo- and hyperglucagonemia on blood glucose homeostasis

scientific article published on November 1, 1976

Evidence of inter-organ amino-acid transport by blood cells in humans

scientific article

Free Fatty Acid Metabolism of Leg Muscles during Exercise in Patients with Obliterative Iliac and Femoral Artery Disease before and after Reconstructive Surgery ⬇️

scientific article published on December 1, 1972

Free fatty acid metabolism in leg muscles during work in patients with intermittent claudication

scientific article published in August 1970

Free fatty acid metabolism of the human heart at rest

scientific article published on July 1969

Fructose-6-phosphate cycling and the pentose cycle in hyperthyroidism

scientific article published in February 1990

Glucose absorption and production following oral glucose: comparison of compartmental and arteriovenous-difference methods

scientific article published in November 1994

Glucose and amino acid metabolism during recovery after exercise ⬇️

scientific article published on June 1, 1973

Glucose homeostasis during prolonged suppression of glucagon and insulin secretion by somatostatin ⬇️

scientific article published on January 1, 1977

Glucose metabolism during leg exercise in man ⬇️

scientific article published on December 1, 1971

Glucose production and gluconeogenesis in adults with uncomplicated falciparum malaria ⬇️

scientific article published on June 1, 1997

Glucose turnover during exercise in man ⬇️

scientific article published on January 1, 1977

Glutamine and Glutamate Metabolism in Normal and Diabetic Subjects ⬇️

scientific article published on August 1, 1973

Gut exchange of glucose and lactate in basal state and after oral glucose ingestion in postoperative patients

scientific article published on June 1990

Heat leakage across the abdominal wall and meal-induced thermogenesis in normal-weight and obese subjects

scientific article published in January 1992

Hepatic disposal of endogenous growth hormone and prolactin in man ⬇️

scientific article published on August 1, 1979

Hepatic extraction and renal production of 3,3'-diiodothyronine and 3',5'-diiodothyronine in man.

scientific article

Hepatic glucose and amino acid metabolism in diabetes

scientific article published on June 1, 1972

Hormonal Interactions in the Regulation of Blood Glucose

scientific article published on January 1, 1979

Human Forearm Muscle Metabolism during Exercise II Uptake, release and oxidation of individual FFA and glycerol ⬇️

scientific article published in January 1968

Human Forearm Muscle Metabolism during Exercise VI. Substrate Utilization in Prolonged Fasting ⬇️

scientific article published on June 1, 1971

Human Forearm Muscle Metabolism during Exercise: V. Quantitative Aspects of Glucose Uptake and Lactate Production during Prolonged Exercise ⬇️

scientific article published on August 1, 1970

Hypoxemia cured by liver transplantation.

scientific article published in February 1990

In vivo biodistribution and pharmacokinetics of (18)F-labeled human C-peptide: evaluation in monkeys using positron emission tomography

scientific article

Influence of Age on the Local Circulatory Adaptation to Leg Exercise ⬇️

scientific article published on February 1, 1974

Influence of Arginine on Splanchnic Glucose Metabolism in Man ⬇️

scientific article published on February 1, 1979

Influence of C-peptide on early glomerular changes in diabetic mice

scientific article published in July 2006

Influence of Endogenous Insulin Secretion on Splanchnic Glucose and Amino Acid Metabolism in Man ⬇️

scientific article published on August 1, 1971

Influence of Oral Glucose Ingestion on Splanchnic Glucose and Gluconeogenic Substrate Metabolism in Man ⬇️

scientific article published on May 1, 1975

Influence of beta-adrenergic blockade on glucose-induced thermogenesis in man ⬇️

scientific article published on September 1, 1983

Influence of contraceptive steroids on the turnover of plasma free arachidonic and oleic acids

scientific article published on January 1, 1977

Influence of growth hormone on splanchnic glucose production in man ⬇️

scientific article published on December 1, 1977

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange ⬇️

scientific article published on October 1, 1978

Influence of hyperthyroidism on splanchnic exchange of glucose and gluconeogenic precursors

scientific article published on April 1981

Influence of lactate infusion on glucose and FFA metabolism in man

scientific article published on March 1, 1976

Influence of physiologic hyperglucagonemia on basal and insulin-inhibited splanchnic glucose output in normal man ⬇️

scientific article published on September 1, 1976

Influence of somatostatin on carbohydrate disposal and absorption in diabetes mellitus ⬇️

scientific article published on December 4, 1976

Influence of somatostatin on splanchnic glucose metabolism in postabsorptive and 60-hour fasted humans ⬇️

scientific article published on February 1, 1977

Infusion of ornithine-alpha-ketoglutarate in healthy subjects: effects on protein metabolism

scientific article published in May 1985

Insulin binding monitored by fluorescence correlation spectroscopy

scientific article

Insulin resistance in uremia

scientific article published on February 1981

Insulin, glucagon, and somatostatin in normal physiology and diabetes mellitus

scientific article published on December 1, 1976

Intravenous and subcutaneous administration of a long-acting somatostatin analogue: effects on glucose metabolism and splanchnic haemodynamics in healthy subjects

scientific article published in April 1989

Intravenous infusion of alpha-oxoisocaproate: influence on amino acid and nitrogen metabolism in patients with liver cirrhosis

scientific article published in March 1982

Is intravenous administration of branched chain amino acids effective in the treatment of hepatic encephalopathy? A multicenter study.

scientific article

Lack of a gastrointestinal mediator of insulin action in maturity-onset diabetes ⬇️

scientific article published on November 18, 1978

Large-surface biosensor technology for enhanced recovery in protein characterization

scientific article

Leg Blood Flow during Exercise in Man ⬇️

scientific article published on November 1, 1971

Leg blood flow during exercise in patients with occlusion of the iliac artery: pre- and postoperative studies

scientific article published in November 1973

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose

scientific article published in May 1998

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose

scientific article

Liver and kidney metabolism during prolonged starvation ⬇️

scientific article published in March 1969

Loss of Pulsatile Insulin Secretion: A Factor in the Pathogenesis of Type 2 Diabetes? ⬇️

scientific article published on September 1, 2012

Meal-induced rise in resting energy expenditure in patients with complete cervical spinal cord lesions

scientific article published in July 1993

Molecular and cellular effects of C-peptide--new perspectives on an old peptide

scientific article published on January 2004

Molecular effects of proinsulin C-peptide

scientific article

Muscle Fiber Characteristics in Healthy Men and Patients with Juvenile Diabetes ⬇️

scientific article published on January 1, 1979

Muscle metabolism during exercise in patients with Parkinson's disease.

scientific article

New tricks by an old dog.

scientific article published on January 2008

Nitrogen metabolism of the human brain

scientific article published on November 1983

Noninvasive tracing of Krebs cycle metabolism in liver

scientific article published in April 1991

Normalization of hepatic glucose regulation despite systemic insulin delivery. Studies in patients with pancreatic transplantation for Type 1 (insulin-dependent) diabetes mellitus ⬇️

scientific article published on May 1, 1991

Normalization of ventilation/perfusion relationships after liver transplantation in patients with decompensated cirrhosis: evidence for a hepatopulmonary syndrome.

scientific article published in December 1990

Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism

scientific article published on 29 May 2007

Onset of Angina Pectoris in Relation to Circulatory Adaptation during Arm and Leg Exercise ⬇️

scientific article published on September 1, 1971

Origins of the hydrogen bound to carbon 1 of glucose in fasting: significance in gluconeogenesis quantitation

scientific article published in October 1999

Paroxysmal ventricular tachycardia without organic heart disease. A case report describing its provocation and five-year follow-up

scientific article published on July 1, 1971

Pentose pathway in human liver

scientific article

Physiological effects and therapeutic potential of proinsulin C-peptide

scientific article

Plasma glucagon levels in exercising man.

scientific article published in July 1972

Plasma lipolytic activity and substrate oxidation after intravenous administration of heparin and a low molecular weight heparin fragment

scientific article published in November 1990

Precise determination of glucose-d(2)/glucose ratio in human serum and plasma by APCI LC-MS/MS.

scientific article

Proinsulin C-peptide and its C-terminal pentapeptide: degradation in human serum and Schiff base formation with subsequent CO2 incorporation

scientific article

Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects

scientific article published on August 2006

Proinsulin C-peptide--a consensus statement

scientific article

Protein and amino acid metabolism during early starvation as reflected by excretion of urea and methylhistidines

scientific article

Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients

scientific article

Protein synthesis in skeletal muscle during starvation and refeeding: Comparison of data from intact muscle and muscle biopsy material ⬇️

scientific article published on November 1, 1990

Protein turnover and amino acid metabolism in the regulation of gluconeogenesis

scientific article published on April 1, 1974

Quantification of the pathways followed in hepatic glycogen formation from glucose.

scientific article published on May 1988

Quantifying gluconeogenesis during fasting

scientific article published in December 1997

Quantitation of the pathways of hepatic glycogen formation on ingesting a glucose load

scientific article published on December 1987

Renal Substrate Exchange in Human Diabetes Mellitus ⬇️

scientific article published on August 1, 1975

Renoprotective Effects of C-Peptide on Type 1 Diabetes

Results following anterior levator-plasty

scientific article published in April 1988

Role of C-peptide in human physiology

scientific article

Role of basal glucagon levels in the regulation of splanchnic glucose output and ketogenesis in insulin-deficient humans ⬇️

scientific article published on June 1, 1984

Role of cyclic AMP in glucagon-induced stimulation of hepatic glucose output in man ⬇️

scientific article published on December 1, 1979

Sensitivity of insulin secretion to feedback inhibition by hyperinsulinaemia.

scientific article published in September 1981

Separate functional features of proinsulin C-peptide

scientific article published on August 2005

Specific binding of proinsulin C-peptide to human cell membranes

scientific article published on November 1999

Specific binding of proinsulin C-peptide to intact and to detergent-solubilized human skin fibroblasts

scientific article

Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus ⬇️

scientific article published on June 1, 1975

Splanchnic and peripheral glucose and amino acid metabolism in diabetes mellitus ⬇️

scientific article published on July 1, 1972

Splanchnic and peripheral glucose and lactate metabolism during and after prolonged arm exercise

scientific article

Splanchnic and renal exchange of infused fructose in insulin-deficient type 1 diabetic patients and healthy controls

scientific article published on January 1989

Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease

scientific article published on 27 June 2010

Splanchnic blood flow and oxygen uptake during cardiopulmonary bypass

scientific article

Splanchnic glucose and amino acid metabolism in obesity

scientific article

Splanchnic glucose and muscle glycogen metabolism after glucose feeding during postexercise recovery

scientific article published on September 1, 1978

Splanchnic regulation of glucose production

scientific article published on January 2007

Substance P: a pioneer amongst neuropeptides

scientific article

Substrate Utilization in Paretic Human Forearm Muscle during Electrically Induced Exercise ⬇️

scientific article published on October 1, 1971

Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids

scientific article published in April 1974

Substrate utilization of the lower arm muscles at rest and during work in long term fasting

scientific article published on August 26, 1971

Symposium I: hormone-fuel interactions in normal and diabetic man. The liver as site of insulin and glucagon action in normal, diabetic and obese humans

scientific article published on June 1, 1975

Synergistic interaction between exercise and insulin on peripheral glucose uptake

scientific article published on December 1981

The Clinical Potential of C-Peptide Replacement in Type 1 Diabetes ⬇️

scientific article published on April 1, 2012

The Contrasting Responses of Splanchnic and Renal Glucose Output to Gluconeogenic Substrates and to Hypoglucagonemia in 60-h-fasted Humans ⬇️

scientific article published on August 1, 1980

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans

scientific article published in May 2005

The effect of local anaesthetics on the central circulation and respiration in man and dog ⬇️

scientific article published in January 1968

The effect of mepivacaine and lidocaine on forearm resistance and capacitance vessels in man ⬇️

scientific article published in January 1970

The influence of human C-peptide on renal function and glucose utilization in type 1 (insulin-dependent) diabetic patients

scientific article published in February 1992

The relevance of C-Peptide in diabetes and its complications: an introduction to the special issue

scientific article published on 10 November 2009

The structure, molecular interactions and bioactivities of proinsulin C-peptide correlate with a tripartite molecule

scientific article

Thermic effect of glucose in man. Obligatory and facultative thermogenesis

scientific article published on November 1984

Thermogenic response to intravenous nutrition in patients with cirrhosis

scientific article published on September 1, 1992

Total and net muscle protein breakdown in infection determined by amino acid effluxes

scientific article

Triglyceride, Free Fatty Acid and Carbohydrate Metabolism in Hyperlipaemic (Type IV) and Normolipaemic Subjects on Carbohydrate- or Fat-Rich Diets ⬇️

scientific article published on April 1, 1975

Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise

scientific article

Turnover and splanchnic metabolism of free fatty acids in hyperthyroid patients ⬇️

scientific article published on June 1, 1981

Uptake of individual amino acids by the human brain

scientific article published in January 1973

Uptake of individual free fatty acids by skeletal muscle and liver in man ⬇️

scientific article published on September 1, 1972

Use of 14CO2 in estimating rates of hepatic gluconeogenesis

scientific article published on July 1, 1992

Use of 2H2O for estimating rates of gluconeogenesis. Application to the fasted state

scientific article

Ventilation-perfusion inequality in patients with non-alcoholic liver cirrhosis

scientific article published on June 1991

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