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List of works by Marc Pellegrini

A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

scientific article published on 7 March 2016

ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system

scientific journal article

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

scientific article published on September 2016

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies

scientific article published on 26 April 2009

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

scholarly article

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.

scientific article

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

scientific article (publication date: 21 February 2002)

Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region.

scientific article published on February 2003

Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins

scientific article published on 15 August 2014

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

scholarly article

CRISPR/Cas9-The ultimate weapon to battle infectious diseases?

scientific article

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles

scientific article published on 3 August 2016

Cellular FLICE-inhibitory protein is required for T cell survival and cycling

scientific article

Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.

scientific article

Changing treatment paradigms for patients with plasma cell myeloma: impact upon immune determinants of infection

scientific article published on 10 February 2014

Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice

scientific article (publication date: 3 October 2016)

Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia

scientific article published on 08 September 2018

Current and emerging therapies to combat persistent intracellular pathogens

scientific article published on 30 April 2019

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

scientific article published on 18 October 2017

Editorial overview: Offence is the best defense: host-pathogen interactions driving evolution of human immunity and the germs we live with

scientific article published in October 2017

Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis.

scientific article published on 20 April 2015

Erratum: Corrigendum: The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

scholarly article published in Nature Immunology

FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells.

scientific article published on 19 May 2005

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

scientific article

Fas regulates neutrophil lifespan during viral and bacterial infection

scientific article

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

scientific article

Fighting cancers from within: augmenting tumor immunity with cytokine therapy

scientific article published on 17 June 2010

Granzyme K-deficient mice show no evidence of impaired antiviral immunity.

scientific article published on 21 April 2017

Guarding effector T-cell survival: all for one, Mcl-1 for all?

scientific article published in August 2013

Hematopoietic cell-derived interferon controls viral replication and virus-induced disease

scientific article published on 29 October 2008

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

scientific journal article

Host pathogen interactions at the coalface of immunity

scientific article

Hydrodynamic Injection as a Method of Gene Delivery in Mice: A Model of Chronic Hepatitis B Virus Infection

scientific article published on January 2016

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.

scientific article

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

scientific article published on 03 February 2011

Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?

scientific article

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

scientific article

Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection

scientific article published on 19 December 2011

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

scientific article published on 26 August 2020

Mycobacterium tuberculosis: Rewiring host cell signaling to promote infection.

scientific article published on 15 December 2017

Mycobacterium tuberculosis: prePPARing and Maintaining the Replicative Niche

scientific article published on 14 August 2018

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

scientific article published on 28 March 2016

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

scientific article

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

scientific article published on 11 December 2017

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

scientific article

Predicting Risk of Infection in Patients with Newly Diagnosed Multiple Myeloma: Utility of Immune Profiling

scientific article published on 5 October 2017

Promoting immunity during chronic infection--the therapeutic potential of common gamma-chain cytokines

scientific article published on 14 May 2013

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

scientific article

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

scientific article published on 13 April 2016

Role of proapoptotic BH3-only proteins in Listeria monocytogenes infection

scientific article published on 11 April 2016

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

scientific article published on 7 September 2017

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation

scientific article

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim ⬇️

scientific article published on November 17, 2003

T-lymphocyte death during shutdown of an immune response

scientific article published in November 2004

TB incidence and characteristics in the remote gulf province of Papua New Guinea: a prospective study

scientific article

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice

scientific article

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

scientific article published on 11 May 2022

The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

scientific article published on 22 September 2013

Therapeutic manipulation of host cell death pathways to facilitate clearance of persistent viral infections

scientific article published on 9 January 2018

Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection.

scientific article

Tumor immune therapy: lessons from infection and implications for cancer - can IL-7 help overcome immune inhibitory networks?

scientific article published on July 2010

Vaccines licensed and in clinical trials for the prevention of dengue

scientific article published on 14 February 2017

c-Rel but not NF-κB1 is important for T regulatory cell development

scientific article published on 01 March 2010

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