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List of works by Klaas Pjm van Gisbergen

A central role for Notch in effector CD8(+) T cell differentiation

scientific article

A non-canonical function of Ezh2 preserves immune homeostasis.

scientific article published on 21 February 2017

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

scientific article published on 08 July 2022

Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.

scientific article

Armed and Ready: Transcriptional Regulation of Tissue-Resident Memory CD8 T Cells

scientific article published on 30 July 2018

Author Correction: Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

scientific article published on 01 April 2019

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation.

scientific article published on 5 December 2011

Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans

scientific journal article

Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells

scientific article published on 16 August 2018

CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.

scientific article published on 10 April 2013

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

scientific article published on 26 March 2012

Circulating memory CD8+ T cells are limited in forming CD103+ tissue-resident memory T cells at mucosal sites after reinfection

scientific article published on 06 August 2020

Close encounters of neutrophils and DCs

scientific article published on 22 September 2005

Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin.

scientific article published on July 2005

Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation.

scientific article

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.

scientific article

Eosinophil differentiation in the bone marrow is inhibited by T cell-derived IFN-gamma.

scientific article published on 29 June 2010

GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo.

scientific article

Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia.

scientific article published on 24 June 2016

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

scientific journal article

Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells

scientific article

Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

scientific article published on 28 January 2019

Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity

scientific article

Molecular mechanisms that set the stage for DC-T cell engagement.

scientific article published on 2 December 2004

Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation

scientific journal article

Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. ⬇️

scientific article published on April 2005

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow

scientific article published on 02 April 2019

Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.

scientific article published on 31 December 2012

Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation.

scientific article published in May 2009

T RM maintenance is regulated by tissue damage via P2RX7

scientific article published on 01 December 2018

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells.

scientific article published on 11 May 2016

The Transcription Factor Hobit Identifies Human Cytotoxic CD4+ T Cells.

scientific article published on 24 March 2017

The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.

scientific article published on September 2012

The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes.

scientific article

Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses

scientific article published on 13 July 2020

Tissue-resident memory T cells at the center of immunity to solid tumors

scientific article published on 18 May 2018

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