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List of works by Paul A. Gleeson

A novel mammalian retromer component, Vps26B.

scientific article

A novel method for isolating mononuclear cells from the stomachs of mice with experimental autoimmune gastritis

scientific article published on 01 January 1995

A role for SNX5 in the regulation of macropinocytosis

scientific article

A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

scholarly article

Alpha and beta subunits of the gastric H+/K(+)-ATPase are concordantly targeted by parietal cell autoantibodies associated with autoimmune gastritis.

scientific article published on January 1993

Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway

scientific article published on 20 December 2016

Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis

scientific article published on 01 June 1996

Antigenic determinants of a plant proteoglycan, the Gladiolus style arabinogalactan-protein

scientific article

Application of flow cytometry to analyze intracellular location and trafficking of cargo in cell populations.

scientific article

Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.

scientific article published on 5 January 2012

Autoimmune gastritis: tolerance and autoimmunity to the gastric H+/K+ ATPase (proton pump)

scientific article published on January 1, 1992

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

scientific article

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

scientific article published on 10 August 2017

CD4+ CD25+ regulatory T cells modulate the T-cell and antibody responses in helicobacter-infected BALB/c mice

scientific article

CD4+CD25+ regulatory T cells inhibit the antigen-dependent expansion of self-reactive T cells in vivo

scientific article published on 01 February 2006

Carbohydrate composition of the oligosaccharide units of the haemagglutinin from the Hong Kong influenza virus A/Memphis/102/72.

scientific article published on September 1980

Carbohydrates and antigen recognition by T cells.

scientific article published on September 1997

Cargo Sorting at the trans-Golgi Network for Shunting into Specific Transport Routes: Role of Arf Small G Proteins and Adaptor Complexes

scientific article published on 03 June 2019

Cargo trafficking between endosomes and the trans-Golgi network.

scientific article published on 14 July 2013

Characterization of the hydroxyproline-rich protein core of an arabinogalactan-protein secreted from suspension-cultured Lolium multiflorum (Italian ryegrass) endosperm cells.

scientific article published on December 1989

Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration

scientific article

Conjugation of Transferrin to Azide-Modified CdSe/ZnS Core-Shell Quantum Dots using Cyclooctyne Click Chemistry

scientific article published on 20 September 2012

Diagnostic ELISA for parietal cell autoantibody using tomato lectin-purified gastric H+/K(+)-ATPase (proton pump).

scientific article published in January 1992

Domains of the TGN: coats, tethers and G proteins.

scientific article published on May 2004

Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions.

scientific article

Effect of glycosylation inhibitors on the structure and function of the murine transferrin receptor.

scientific article published on December 1989

Emerging Insights into the Roles of Membrane Tethers from Analysis of Whole Organisms: The Tip of an Iceberg?

scientific article

Endogenous H/K ATPase -Subunit Promotes T Cell Tolerance to the Immunodominant Gastritogenic Determinant

scientific article published on 01 September 2002

Endosome-to-Golgi transport pathways in physiological processes.

scientific article published on March 2011

Expression of a gastric autoantigen in pancreatic islets results in non-destructive insulitis after neonatal thymectomy

scientific article published on 01 September 1995

Expression of the gastric H/K-ATPase alpha-subunit in the thymus may explain the dominant role of the beta-subunit in the pathogenesis of autoimmune gastritis

scientific article published on 01 January 1997

Fast freeze-fixation/freeze-substitution reveals the secretory membranes of the gastric parietal cell as a network of helically coiled tubule. A new model for parietal cell transformation

scientific article published on 01 March 1995

FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages

scientific article published on 01 October 2019

Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling

scientific article published on 19 August 2019

From coiled tubules to a secretory canaliculus: a new model for membrane transformation and acid secretion by gastric parietal cells

scientific article published on 01 February 1996

GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.

scientific article published on 15 November 2017

GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network.

scientific article

Gastric H+, K+-adenosine triphosphatase β subunit is required for normal function, development, and membrane structure of mouse parietal cells

article

Gastric parietal cell acid secretion in mice can be regulated independently of H/K ATPase endocytosis.

scientific article published in July 2004

Gastric parietal cell development: expression of the H+/K+ ATPase subunits coincides with the biogenesis of the secretory membranes

scientific article published on 01 June 1993

Genetic defect in N-acetylglucosaminyltransferase I gene of a ricin-resistant baby hamster kidney mutant.

scientific article published on December 1998

Glycosylation defect in Lec1 Chinese hamster ovary mutant is due to a point mutation in N-acetylglucosaminyltransferase I gene.

scientific article published on November 1996

Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis

scientific article published on 17 June 2004

Half-life-extended recombinant coagulation factor IX-albumin fusion protein is recycled via the FcRn-mediated pathway.

scientific article published on 9 March 2018

Helios defines T cells being driven to tolerance in the periphery and thymus

scientific article published on 05 June 2014

High-throughput quantitation of intracellular trafficking and organelle disruption by flow cytometry.

scientific article published on 11 March 2014

Homing and adhesion molecules in autoimmune gastritis

scientific article published on 01 February 2000

Human autoantibodies as reagents to conserved Golgi components. Characterization of a peripheral, 230-kDa compartment-specific Golgi protein ⬇️

scientific article published on October 5, 1992

Identification of a Golgi-localised GRIP domain protein from Arabidopsis thaliana

scientific article published on 22 June 2004

Identification of a gastritogenic epitope of the H/K ATPase beta-subunit

scientific article published on 01 January 1999

Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling

scientific article published on 25 October 2011

Imaging and Quantitation Techniques for Tracking Cargo along Endosome-to-Golgi Transport Pathways

scientific article published on 22 February 2013

Immunization with gastric H+/K(+)-ATPase induces a reversible autoimmune gastritis

scientific article published on 01 September 1997

Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis

scientific article

Impact of glycans on T-cell tolerance to glycosylated self-antigens

scientific article published on 15 July 2008

Increased endogenous antigen presentation in the periphery enhances susceptibility to inflammation-induced gastric autoimmunity in mice.

scientific article published on 19 October 2016

Independent trafficking of the KCNQ1 K+ channel and H+-K+-ATPase in gastric parietal cells from mice.

scientific article published on 15 November 2012

Interferon-gamma is required during the initiation of an organ-specific autoimmune disease

scientific article published on 01 July 1996

Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture

scientific article published on 12 December 2018

Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis.

scientific article published on 8 July 2013

Intracellular sorting and transport of proteins

scientific article

Intracellular trafficking of the β-secretase and processing of amyloid precursor protein

scientific article published on 10 August 2011

Isolation of an arabinogalactan protein by lectin affinity chromatography on tridacnin-sepharose 4B

scientific article published on January 1, 1979

Isolation, culture and adenoviral transduction of parietal cells from mouse gastric mucosa

scientific article

Leishmania adaptor protein-1 subunits are required for normal lysosome traffic, flagellum biogenesis, lipid homeostasis, and adaptation to temperatures encountered in the mammalian host.

scientific article published on 30 May 2008

Macropinocytosis in Different Cell Types: Similarities and Differences

scientific article published on 03 August 2020

Mammalian GRIP domain proteins differ in their membrane binding properties and are recruited to distinct domains of the TGN.

scientific article

Membrane tethering

scientific article

Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia

scientific article published on 01 April 1991

N-linked oligosaccharides of the murine transferrin receptor from a plasmacytoma cell line. Comparison with total cellular N-glycans.

scientific article published on October 1990

New insights into membrane trafficking and protein sorting.

scientific article published on January 2007

Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia

scientific article published on 01 January 1995

Organ-specific autoimmunity induced by lymphopenia.

scientific article

Poly-N-acetyllactosamine-specific tomato lectin interacts with gastric parietal cells. Identification of a tomato-lectin binding 60-90 X 10(3) Mr membrane glycoprotein of tubulovesicles

scientific article published on 01 April 1990

Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules. Golgi localization involves active retention.

scientific article published on December 1994

Prevention of autoimmune gastritis in mice requires extra-thymic T-cell deletion and suppression by regulatory T cells

scientific article published on 02 June 2007

Promiscuous thymic expression of an autoantigen gene does not result in negative selection of pathogenic T cells

scientific article published on 01 November 2005

Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin.

scientific article

Rapamycin results in Bim-mediated loss of thymic regulatory T cells during development in organ culture.

scientific article published on 30 June 2016

Rapid purification of the gastric H+/K+-ATPase complex by tomato-lectin affinity chromatography ⬇️

scientific article published on April 1, 1992

Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation

scientific article published on 01 September 2005

Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages

scientific article published on 25 September 2012

Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction

scientific article published on 10 October 2008

Regulation of gastric epithelial cell development revealed in H+/K+-ATPase β-subunit- and gastrin-deficient mice

scientific article published on 01 December 2001

Renal expression of the gene encoding the gastric H(+)-K(+)-ATPase beta-subunit

scientific article published on 01 March 1995

Requirements for autoimmune responses to mouse gastric autoantigens

article

Reverse immunoaffinity chromatography: application to the purification of the 60- to 90-kDa gastric parietal cell autoantigen associated with autoimmune gastritis

scientific article published on 01 May 1991

SNX5 is essential for efficient macropinocytosis and antigen processing in primary macrophages

scientific article

Shaping the T cell repertoire to a bona fide autoantigen: lessons from autoimmune gastritis.

scientific article

Shaping the T-cell repertoire in the periphery

scientific article published on 16 November 2010

Signal dependent transport of a membrane cargo from early endosomes to recycling endosomes

scientific article published on 17 June 2017

Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation

scientific article

Sorting nexin 5 selectively regulates dorsal-ruffle-mediated macropinocytosis in primary macrophages

scientific article published on 12 October 2015

Stable expression of the human immunodeficiency virus type 1 envelope glycoprotein in transfected L cells.

scientific article published on December 1992

Steady-state localization of a medial-Golgi glycosyltransferase involves transit through the trans-Golgi network

scientific article

Structural studies on the major component of Gladiolus style mucilage, an arabinogalactan-protein.

scientific article published on September 1979

TGN golgins, Rabs and cytoskeleton: regulating the Golgi trafficking highways.

scientific article published on 12 March 2010

Targeting of proteins to the Golgi apparatus

article

Targeting of the GRIP domain to the trans-Golgi network is conserved from protists to animals.

scientific article published in September 2002

The Function of the Golgi Ribbon Structure - An Enduring Mystery Unfolds!

scientific article published on 6 October 2017

The GRIP domain is a specific targeting sequence for a population of trans-Golgi network derived tubulo-vesicular carriers.

scientific article published in May 2001

The Golgi apparatus in the endomembrane-rich gastric parietal cells exist as functional stable mini-stacks dispersed throughout the cytoplasm

scientific article published on December 2011

The Golgi architecture and cell sensing.

scientific article

The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity.

scientific article published on 28 December 2017

The Golgi-targeting sequence of the peripheral membrane protein p230

scientific article published on 01 June 1999

The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network

scientific article

The localization of the Golgin GCC185 is independent of Rab6A/A' and Arl1

scientific article published on 01 August 2009

The mouse gastric H,K-ATPase beta subunit. Gene structure and co-ordinate expression with the alpha subunit during ontogeny ⬇️

scientific article published on January 15, 1992

The nature of callose produced during self-pollination inSecale cereale.

scientific article published in October 1980

The parietal cell autoantigens recognized in neonatal thymectomy-induced murine gastritis are the alpha and beta subunits of the gastric proton pump [corrected]

scientific article published on 01 August 1991

The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation

scientific article (publication date: 13 December 2002)

The regulation of endosome-to-Golgi retrograde transport by tethers and scaffolds.

scientific article published on 08 April 2011

The role of CD4+ CD25+ immunoregulatory T cells in the induction of autoimmune gastritis

article by Karen L Laurie et al published December 2002 in Immunology & Cell Biology

The role of endosomes in innate and adaptive immunity

scientific article published on 12 March 2014

The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease

scientific article published on 11 January 2019

The role of natural killer cells in the induction of autoimmune gastritis

scientific article published on 01 January 2001

The signal for Golgi retention of bovine beta 1,4-galactosyltransferase is in the transmembrane domain

scientific article published on 01 June 1992

The sweet side of immunology: glycobiology of the immune system

scientific article published on 01 October 2008

The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers

scientific article

The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure

scientific article

The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons

scientific article published on 13 December 2018

The transmembrane and flanking sequences of beta 1,2-N-acetylglucosaminyltransferase I specify medial-Golgi localization.

scientific article published on December 1992

Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells

scientific article published in May 2004

Tolerance and autoimmunity to a gastritogenic peptide in TCR transgenic mice

scientific article published on 01 March 2000

Tracking protein aggregation and mislocalization in cells with flow cytometry

scientific article

Transient Treg-cell depletion in adult mice results in persistent self-reactive CD4(+) T-cell responses

scientific article published on 02 November 2014

Transient systemic inflammation does not alter the induction of tolerance to gastric autoantigens by migratory dendritic cells

scientific article published on 23 April 2014

Visualisation of macropinosome maturation by the recruitment of sorting nexins

scientific article published on 12 September 2006

p230 is associated with vesicles budding from the trans-Golgi network

scientific article

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